| 1 |
2022 |
|
poly |
| 2 |
2022 |
1-Deoxynojirimycin attenuates septic cardiomyopathy by regulating oxidative stress, apoptosis, and inflammation via the JAK2/STAT6 signaling pathway. |
JAK/STAT, LPS |
| 3 |
2022 |
5-C-Branched Deoxynojirimycin: Strategy for Designing a 1-Deoxynojirimycin-Based Pharmacological Chaperone with a Nanomolar Affinity for Pompe Disease. |
GAA, rhGAA, Tm |
| 4 |
2022 |
Antiviral effects of deoxynojirimycin (DNJ)-based iminosugars in dengue virus-infected primary dendritic cells. |
DCs, DENV, DGJ, ER, imDCs, MDMphis |
| 5 |
2022 |
Bambus[4,6]urils as Dual Scaffolds for Multivalent Iminosugar Presentation and Ion Transport: Access to Unprecedented Glycosidase-Directed Anion Caging Agents. |
CuAAC |
| 6 |
2022 |
Effect of 1-Deoxynojirimycin on insulin resistance in prediabetic mice based on next-generation sequencing and intestinal microbiota study. |
ELISA, IL-6, ITT, LPS, NGS, OGTT, STZ, T2DM, TLR4, TNF-alpha |
| 7 |
2022 |
Hepatoprotective effects of different mulberry leaf extracts against acute liver injury in rats by alleviating oxidative stress and inflammatory response. |
D-GalN, LPS, MEE |
| 8 |
2022 |
Metabolomic Profiling and Identification of Antioxidant and Antidiabetic Compounds from Leaves of Different Varieties of Morus alba Linn Grown in Kashmir. |
--- |
| 9 |
2022 |
Mixed Mulberry Fruit and Mulberry Leaf Fermented Alcoholic Beverages: Assessment of Chemical Composition, Antioxidant Capacity In Vitro and Sensory Evaluation. |
GABA |
| 10 |
2022 |
Molecular cloning, expression, and functional analysis of copper amine oxidase gene from mulberry (Morus alba L.). |
--- |
| 11 |
2022 |
Mulberry-Derived 1-Deoxynojirimycin Prevents Type 2 Diabetes Mellitus Progression via Modulation of Retinol-Binding Protein 4 and Haptoglobin. |
Drp1, HDHD-3 |
| 12 |
2022 |
Novel active compounds and the anti-diabetic mechanism of mulberry leaves. |
ADORA1, AKT1, FA, GSK-3beta, MLF, MLP, PPARgamma, T2DM |
| 13 |
2022 |
Rapid Screening of Nonalkaloid α-Glucosidase Inhibitors from a Mulberry Twig Extract Using Enzyme-Functionalized Magnetic Nanoparticles Coupled with UPLC-MS/MS. |
--- |
| 14 |
2022 |
Structure of an iminosugar complex of a glycoside hydrolase family 5 lichenase provides insights into the active site. |
GH5_36 |
| 15 |
2021 |
An overview of therapeutic potential of N-alkylated 1-deoxynojirimycin congeners. |
--- |
| 16 |
2021 |
Development and evaluation of 1-deoxynojirimycin sustained-release delivery system: In vitro and in vivo characterization studies. |
Cmax, Tmax |
| 17 |
2021 |
Evaluation and development of a novel pre-treatment method for mulberry leaves to enhance their bioactivity via enzymatic degradation of GAL-DNJ to DNJ. |
GAL-DNJ |
| 18 |
2021 |
Genome Analysis of Streptomyces nojiriensis JCM 3382 and Distribution of Gene Clusters for Three Antibiotics and an Azasugar across the Genus Streptomyces. |
NJ |
| 19 |
2021 |
Hybrid Multivalent Jack Bean alpha-Mannosidase Inhibitors: The First Example of Gold Nanoparticles Decorated with Deoxynojirimycin Inhitopes. |
JBalpha-man |
| 20 |
2021 |
In Vivo Functional Verification of Four Related Genes Involved in the 1-Deoxynojirimycin Biosynthetic Pathway in Mulberry Leaves. |
--- |
| 21 |
2021 |
Morus alba L. (Sangzhi) alkaloids (SZ-A) exert anti-inflammatory effects via regulation of MAPK signaling in macrophages. |
Arg, BMDM, DAB, ELISA, FAG, LPS |
| 22 |
2021 |
Mulberry leaves ameliorate diabetes via regulating metabolic profiling and AGEs/RAGE and p38 MAPK/NF-κB pathway. |
FBG, HK, PK, T2DM, TCHO, TG |
| 23 |
2021 |
Pb contaminated soil influence on aboveground biomass and bioactive compounds in leaves of mulberry. |
PRD |
| 24 |
2021 |
Study on the Synthesis and Biological Activities of N-Alkylated Deoxynojirimycin Derivatives with a Terminal Tertiary Amine. |
--- |
| 25 |
2021 |
Synthesis and Structural Revision of Glyphaeaside C. |
--- |
| 26 |
2021 |
[1-deoxynojirimycin alleviates liver fibrosis induced by type 2 diabetes in mice]. |
BW, ColA2, DHE, PSC, SOD, TC, TG |
| 27 |
2020 |
1-Deoxynojirimycin from mulberry leaves changes gut digestion and microbiota composition in geese. |
--- |
| 28 |
2020 |
A randomized controlled study of dose-finding, efficacy, and safety of mulberry leaves on glycemic profiles in obese persons with borderline diabetes. |
FPG |
| 29 |
2020 |
Comparative Transcriptome Analysis of Key Reductase Genes Involved in the 1-Deoxynojirimycin Biosynthetic Pathway in Mulberry Leaves and Cloning, Prokaryotic Expression, and Functional Analysis of MaSDR1 and MaSDR2. |
--- |
| 30 |
2020 |
Iminosugars With Endoplasmic Reticulum alpha-Glucosidase Inhibitor Activity Inhibit ZIKV Replication and Reverse Cytopathogenicity in vitro. |
ER-AGI, hpi, ZIKV |
| 31 |
2020 |
Intestinal Absorption and Tissue Distribution of Aza-Sugars from Mulberry Leaves and Evaluation of Their Transport by Sugar Transporters. |
GAL-DNJ, GLUT |
| 32 |
2020 |
Mulberry leaf attenuates atherosclerotic lesions in patients with coronary heart disease possibly via 1-Deoxynojirimycin: A placebo-controlled, double-blind clinical trial. |
CHD, HPLC, IMT, MLD, MLD |
| 33 |
2020 |
N-Nonyloxypentyl-l-Deoxynojirimycin Inhibits Growth, Biofilm Formation and Virulence Factors Expression of Staphylococcus aureus. |
l-NPDNJ, MIC |
| 34 |
2020 |
Strategy for Designing Selective Lysosomal Acid alpha-Glucosidase Inhibitors: Binding Orientation and Influence on Selectivity. |
ER, GAA, LAB |
| 35 |
2020 |
Supplementation of Bacillus amyloliquefaciens AS385 culture broth powder containing 1-deoxynojirimycin in a high-fat diet altered the gene expressions related to lipid metabolism and insulin signaling in mice epididymal white adipose tissue. |
CBP, HFD |
| 36 |
2020 |
Suppression of N-glycan processing enzymes by deoxynojirimycin in tomato (Solanum lycopersicum) fruit. |
--- |
| 37 |
2020 |
Synthesis and Glycosidase Inhibition Properties of Calix[8]arene-Based Iminosugar Click Clusters. |
CuAAC, JBalpha-man |
| 38 |
2020 |
The Gut Microbiota-Produced Indole-3-Propionic Acid Confers the Antihyperlipidemic Effect of Mulberry-Derived 1-Deoxynojirimycin. |
IPA, MLE, TCM |
| 39 |
2020 |
Total flavonoids, total phenolics, 1-deoxynojirimycin content and alpha-glucosidase inhibitory activity of Thai silkworm races (Bombyx mori Linn.). |
--- |
| 40 |
2019 |
1-Deoxynojirimycin improves high fat diet-induced nonalcoholic steatohepatitis by restoring gut dysbiosis. |
HFD, NASH |
| 41 |
2019 |
1-Deoxynojirimycin in Mulberry (Morus indica L.) Leaves Ameliorates Stable Angina Pectoris in Patients With Coronary Heart Disease by Improving Antioxidant and Anti-inflammatory Capacities. |
BSS, CHD, CRP, HAMD, IkBalpha, IKK, IL-6, MDA, NF-kappaB, SAP, SAS, SOD, TNF-alpha |
| 42 |
2019 |
1-Deoxynojirimycin modulates glucose homeostasis by regulating the combination of IR-GlUT4 and ADIPO-GLUT4 pathways in 3T3-L1 adipocytes. |
ADIPO, AMP, GLUT4, IR, PI3K, T2DM |
| 43 |
2019 |
A Novel Strategy to Regulate 1-Deoxynojirimycin Production Based on Its Biosynthetic Pathway in Streptomyces lavendulae. |
--- |
| 44 |
2019 |
Alpha-glucosidase inhibitor 1-Deoxynojirimycin promotes beige remodeling of 3T3-L1 preadipocytes via activating AMPK. |
PPARgamma, PRDM16, Pref-1, TMEM26, UCP1 |
| 45 |
2019 |
An overview of the biological production of 1-deoxynojirimycin: current status and future perspective. |
--- |
| 46 |
2019 |
Effect of 1-Deoxynojirimycin Isolated from Mulberry Leaves on Glucose Metabolism and Gut Microbiota in a Streptozotocin-Induced Diabetic Mouse Model. |
--- |
| 47 |
2019 |
Iminosugars: Effects of Stereochemistry, Ring Size, and N-Substituents on Glucosidase Activities. |
MARV |
| 48 |
2019 |
Physiological Effects and Organ Distribution of Bacillus amyloliquefaciens AS385 Culture Broth Powder Containing 1-Deoxynojirimycin in C57BL/6J Mice. |
CBP |
| 49 |
2019 |
Synthesis and glycosidase inhibition of conformationally locked DNJ and DMJ derivatives exploiting a 2-oxo-C-allyl iminosugar. |
DMJ |
| 50 |
2019 |
Use of a deoxynojirimycin-fluorophore conjugate as a cell-specific imaging probe targeting alpha-glucosidase on cell membranes. |
--- |
| 51 |
2018 |
1-Deoxynojirimycin (DNJ) Ameliorates Indomethacin-Induced Gastric Ulcer in Mice by Affecting NF-kappaB Signaling Pathway. |
CAT, CG, GU, MDA, MOT, SOD, SP, SS, VIP |
| 52 |
2018 |
A toxicological, metabonomic and transcriptional analysis to investigate the property of mulberry 1-deoxynojirimycin against the growth of Samia cynthia ricini. |
LDH, NMR, PCA, RT-qPCR, TCA, THL |
| 53 |
2018 |
Characterization of the PLP-dependent transaminase initiating azasugar biosynthesis. |
--- |
| 54 |
2018 |
Cloning, expression, and functional analysis of lysine decarboxylase in mulberry (Morus alba L.). |
MaLDC |
| 55 |
2018 |
Coating rice with mulberry leaves rich in deoxynojirimycin ameliorates hyperglycemia and dyslipidemia in C57BL/KsJ db/db mice. |
ML, NC |
| 56 |
2018 |
Comparative transcriptome analysis reveals significant metabolic alterations in eri-silkworm (Samia cynthia ricini) haemolymph in response to 1-deoxynojirimycin. |
ddH2O, DEGs, RT-qPCR |
| 57 |
2018 |
d-Fagomine Attenuates High Glucose-Induced Endothelial Cell Oxidative Damage by Upregulating the Expression of PGC-1alpha. |
GR, HUVECs, MDA, ROS, SOD |
| 58 |
2018 |
Evaluation of the anti-hyperglycemic effect and safety of microorganism 1-deoxynojirimycin. |
CSE |
| 59 |
2018 |
Functional analysis of a triplet deletion in the gene encoding the sodium glucose transporter 3, a potential risk factor for ADHD. |
ADHD, hSGLT3, SGLT, WES |
| 60 |
2018 |
Improvement Activity of 1-Deoxynojirimycin in the Growth of Dairy Goat Primary Mammary Epithelial Cell through Upregulating LEF-1 Expression. |
--- |
| 61 |
2018 |
Integrated multi-spectroscopic and molecular docking techniques to probe the interaction mechanism between maltase and 1-deoxynojirimycin, an alpha-glucosidase inhibitor. |
--- |
| 62 |
2018 |
Mulberry leaf extract reduces the glycemic indexes of four common dietary carbohydrates. |
GI, MLE |
| 63 |
2018 |
Mulberry leaves and their potential effects against cardiometabolic risks: a review of chemical compositions, biological properties and clinical efficacy. |
CVD |
| 64 |
2018 |
Neuroprotective effect of 1-Deoxynojirimycin on cognitive impairment, beta-amyloid deposition, and neuroinflammation in the SAMP8 mice. |
BDNF, IL-1beta, IL-6, SAMP8, SAMR1, TNF-alpha |
| 65 |
2018 |
Probing the Inhibitor versus Chaperone Properties of sp-Iminosugars towards Human beta-Glucocerebrosidase: A Picomolar Chaperone for Gaucher Disease. |
GCase |
| 66 |
2018 |
Proteomic-Based Approach to the Proteins Involved in 1-Deoxynojirimycin Accumulation in Silkworm Bombyx mori (Lepidoptera: Bombycidae). |
Ser, TPx |
| 67 |
2018 |
Seasonal variations of iminosugars in mulberry leaves detected by hydrophilic interaction chromatography coupled with tandem mass spectrometry. |
FAG, Gal-DNJ, Glu-FAG |
| 68 |
2018 |
Spectroscopic techniques investigation on the interaction of glucoamylase with 1-deoxynojirimycin: Mechanistic and conformational study. |
--- |
| 69 |
2018 |
Transcriptome analysis and identification of key genes involved in 1-deoxynojirimycin biosynthesis of mulberry (Morus alba L.). |
--- |
| 70 |
2017 |
A UPLC-MS/MS method for simultaneous determination of 1-deoxynojirimycin and N-methyl-1-deoxynojirimycin in rat plasma and its application in pharmacokinetic and absolute bioavailability studies. |
IS, MRM |
| 71 |
2017 |
Central Administration of 1-Deoxynojirimycin Attenuates Hypothalamic Endoplasmic Reticulum Stress and Regulates Food Intake and Body Weight in Mice with High-Fat Diet-Induced Obesity. |
CNS, i.c.v, JAK2, STAT3 |
| 72 |
2017 |
Metabolic changes in the midgut of Eri silkworm after Oral administration of 1-deoxynojirimycin: A 1H-NMR-based metabonomic study. |
NMR, TCA |
| 73 |
2017 |
Metabolic Effect of 1-Deoxynojirimycin from Mulberry Leaves on db/db Diabetic Mice Using Liquid Chromatography-Mass Spectrometry Based Metabolomics. |
--- |
| 74 |
2017 |
Pharmacokinetics, Tissue Distribution, and Elimination of Three Active Alkaloids in Rats after Oral Administration of the Effective Fraction of Alkaloids from Ramulus Mori, an Innovative Hypoglycemic Agent. |
AUC, DAB, FGM |
| 75 |
2016 |
1-Deoxynojirimycin Alleviates Liver Injury and Improves Hepatic Glucose Metabolism in db/db Mice. |
AST, G6Pase, GP, GS, GSK-3beta, HK, IL-1, IL-6, LDL-C, PEPCK, PI3K, PK, PKB, TC, TG, TNF-alpha |
| 76 |
2016 |
A 28-Day Repeated Dose Toxicological Study of an Aqueous Extract of Morus Alba L. |
BW |
| 77 |
2016 |
An Evaluation of 1-Deoxynojirimycin Oral Administration in Eri Silkworm through Fat Body Metabolomics Based on (1) H Nuclear Magnetic Resonance. |
TCA |
| 78 |
2016 |
Comparison of Regulation Mechanisms of Five Mulberry Ingredients on Insulin Secretion under Oxidative Stress. |
C3G, C3R, GK, GLP-1R, OXY, RES |
| 79 |
2016 |
CuAAC click chemistry with N-propargyl 1,5-dideoxy-1,5-imino-D-gulitol and N-propargyl 1,6-dideoxy-1,6-imino-D-mannitol provides access to triazole-linked piperidine and azepane pseudo-disaccharide iminosugars displaying glycosidase inhibitory properties. |
--- |
| 80 |
2016 |
Decreased formation of branched-chain short fatty acids in Bacillus amyloliquefaciens by metabolic engineering. |
BCFAs, ptb |
| 81 |
2016 |
Effect of solar radiation on the functional components of mulberry (Morus alba L.) leaves. |
--- |
| 82 |
2016 |
Evaluation of monovalent and multivalent iminosugars to modulate Candida albicans beta-1,2-mannosyltransferase activities. |
DMJ |
| 83 |
2016 |
Identification and Determination of the Polyhydroxylated Alkaloids Compounds with alpha-Glucosidase Inhibitor Activity in Mulberry Leaves of Different Origins. |
ELSD, HPLC |
| 84 |
2016 |
One pot oxidative dehydration - oxidation of polyhydroxyhexanal oxime to polyhydroxy oxohexanenitrile: A versatile methodology for the facile access of azasugar alkaloids. |
--- |
| 85 |
2016 |
Study of the Aminoglycoside Subsistence Phenotype of Bacteria Residing in the Gut of Humans and Zoo Animals. |
CFU |
| 86 |
2016 |
Synthesis and characterization of novel, conjugated, fluorescent DNJ derivatives for alpha-glucosidase recognition. |
--- |
| 87 |
2016 |
Use of Bacillus amyloliquefaciens HZ-12 for High-Level Production of the Blood Glucose Lowering Compound, 1-Deoxynojirimycin (DNJ), and Nutraceutical Enriched Soybeans via Fermentation. |
alpha-GI, TN, TRS |
| 88 |
2015 |
1-Deoxynojirimycin Alleviates Insulin Resistance via Activation of Insulin Signaling PI3K/AKT Pathway in Skeletal Muscle of db/db Mice. |
AKT, GLUT4, IR-beta, IRS-1, PI3K |
| 89 |
2015 |
A 1H-NMR Based Study on Hemolymph Metabolomics in Eri Silkworm after Oral Administration of 1-Deoxynojirimycin. |
NMR, PCA |
| 90 |
2015 |
Azetidine- and N-carboxylic azetidine-iminosugars as amyloglucosidase inhibitors: synthesis, glycosidase inhibitory activity and molecular docking studies. |
--- |
| 91 |
2015 |
Chronic adjunction of 1-deoxynojirimycin protects from age-related behavioral and biochemical changes in the SAMP8 mice. |
--- |
| 92 |
2015 |
Inhibition of alpha-glucosidase activity by N-deoxynojirimycin analogs in several insect phloem sap feeders. |
NB-DNJ, NN-DNJ |
| 93 |
2015 |
Isolation and SAR studies of bicyclic iminosugars from Castanospermum australe as glycosidase inhibitors. |
--- |
| 94 |
2015 |
Mulberry 1-Deoxynojirimycin Inhibits Adipogenesis by Repression of the ERK/PPARgamma Signaling Pathway in Porcine Intramuscular Adipocytes. |
IMF, RSG |
| 95 |
2015 |
Multiple Comparisons of Glucokinase Activation Mechanisms of Five Mulberry Bioactive Ingredients in Hepatocyte. |
C3G, C3R, GK, GKRP, OXY, RES |
| 96 |
2015 |
Rapid determination of 1-deoxynojirimycin in Morus alba L. leaves by direct analysis in real time (DART) mass spectrometry. |
DART, LOD, SIM |
| 97 |
2015 |
Simultaneous quantification of three active alkaloids from a traditional Chinese medicine Ramulus Mori (Sangzhi) in rat plasma using liquid chromatography-tandem mass spectrometry. |
DAB, ESI, LLOQs, MRM |
| 98 |
2015 |
Synthetic deoxynojirimycin derivatives bearing a thiolated, fluorinated or unsaturated N-alkyl chain: identification of potent alpha-glucosidase and trehalase inhibitors as well as F508del-CFTR correctors. |
--- |
| 99 |
2014 |
1-Deoxynojirimycin attenuates high glucose-accelerated senescence in human umbilical vein endothelial cells. |
HUVECs |
| 100 |
2014 |
1-deoxynojirimycin isolated from Bacillus subtilis improves hepatic lipid metabolism and mitochondrial function in high-fat-fed mice. |
--- |
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