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Abbreviation : DNP
Long Form : diabetic neuropathic pain
No. Year Title Co-occurring Abbreviation
2022 Alleviative effect of microRNA-497 on diabetic neuropathic pain in rats in relation to decreased USP15. miR-497
2022 Dorsal root ganglia P2X4 and P2X7 receptors contribute to diabetes-induced hyperalgesia and the downregulation of electroacupuncture on P2X4 and P2X7. DRG, STZ
2022 Effect of Riluzole on the Expression of HCN2 in Dorsal Root Ganglion Neurons of Diabetic Neuropathic Pain Rats. DRG, HCN2, PWMT, PWTL
2022 Glucagon-like peptide-1 receptor agonist attenuates diabetic neuropathic pain via inhibition of NOD-like receptor protein 3 inflammasome in brain microglia. GLP-RA, NLRP3
2022 GPR177 in A-fiber sensory neurons drives diabetic neuropathic pain via WNT-mediated TRPV1 activation. CSF, DRG, GPR177, TRPV1
2022 Inhibition of phosphorylated calcium/calmodulin-dependent protein kinase IIα relieves streptozotocin-induced diabetic neuropathic pain through regulation of P2X3 receptor in dorsal root ganglia. DRG, PWLs, PWTs, STZ
2022 LncRNA-UC.25 + shRNA Alleviates P2Y14 Receptor-Mediated Diabetic Neuropathic Pain via STAT1. lncRNA, p38 MAPK, STAT1
2022 Long non-coding RNA MSTRG.81401 short hairpin RNA relieves diabetic neuropathic pain and behaviors of depression by inhibiting P2X4 receptor expression in type 2 diabetic rats. lncRNA, MDD, shRNA
2022 Lower / upper extremity F-wave ratio for detecting early diabetic neuropathy. ---
10  2022 Novel Nanotechnological Approaches for Targeting Dorsal Root Ganglion (DRG) in Mitigating Diabetic Neuropathic Pain (DNP). DFU, DPN, DRG, GABA
11  2022 Reactive Oxygen Species Contributes to Type 2 Diabetic Neuropathic Pain via the Thioredoxin-Interacting Protein-NOD-Like Receptor Protein 3-N-Methyl-D-Aspartic Acid Receptor 2B Pathway. caspase-1, IL-1beta, ROS, tNR2B
12  2022 Tannins in the Treatment of Diabetic Neuropathic Pain: Research Progress and Future Challenges. ---
13  2022 The Effect of Yiqi Huoxue Tongluo Decoction on Spinal Cord Microglia Activation and ASK1-MKK3-p38 Signal Pathway in Rats with Diabetic Neuropathic Pain. DM, STZ, YQHX
14  2022 [Effect of electroacupuncture and pretreatment of electroacupuncture on pain sensitization and expression of P2X7R in spinal dorsal horn in rats with diabetic neuropathic pain]. EA, FBG, STZ
15  2022 [Tetrahydropalmatine alleviated diabetic neuropathic pain by inhibiting activation of microglia via p38 MAPK signaling pathway]. ELISA, FBG, FINS, IL-10, IL-1beta, IL-6, iNOS, LPS, MWT, NO, THP, TNF-alpha, TWL
16  2021 Analgesic effect of duloxetine compared to nortryptiline in patients with painful neuropathy: A randomized, double-blind, placebo-controlled trial. VAS
17  2021 cAMP-PKA signaling is involved in regulation of spinal HCN channels function in diabetic neuropathic pain. cAMP-PKA, HCN, MWT
18  2021 Decreased amino acids in the brain might contribute to the progression of diabetic neuropathic pain. DE metabolites, STZ
19  2021 Diabetic neuropathic pain induced by streptozotocin alters the expression profile of non-coding RNAs in the spinal cord of mice as determined by sequencing analysis. circRNAs, DE, lncRNAs, miRNAs, ncRNAs, nt, STZ
20  2021 Fluorocitrate and neurotropin confer analgesic effects on neuropathic pain in diabetic rats via inhibition of astrocyte activation in the periaqueductal gray. FC, GFAP, i.p, MWT, vlPAG
21  2021 Jinmaitong Alleviates Diabetic Neuropathic Pain Through Modulation of NLRP3 Inflammasome and Gasdermin D in Dorsal Root Ganglia of Diabetic Rats. DRG, GSDMD, JMT, MWT, NLRP3, STZ, TFL
22  2021 Koumine modulates spinal microglial M1 polarization and the inflammatory response through the Notch-RBP-Jkappa signaling pathway, ameliorating diabetic neuropathic pain in rats. KM, NP, STZ
23  2021 Novel Mechanism for Memantine in Attenuating Diabetic Neuropathic Pain in Mice via Downregulating the Spinal HMGB1/TRL4/NF-kB Inflammatory Axis. DM, ELISA, HMGB1, IL-1beta, NF-kB, NMDAR1, TLR4, TNF-alpha
24  2021 Reduced Gut Microbiome Diversity in People With HIV Who Have Distal Neuropathic Pain. PD, PWH, PWoH
25  2021 Role of Matrix Metalloproteinases in Myelin Abnormalities and Mechanical Allodynia in Rodents with Diabetic Neuropathy. STZ
26  2021 Serum brain-derived neurotrophic factor levels in patients with diabetic neuropathic pain. BDNF, DN4
27  2021 Small Fiber Functionality in Patients with Diabetic Neuropathic Pain. IENFDs, IGT, LASCA
28  2021 Streptozotocin-Induced Hyperglycemia Affects the Pharmacokinetics of Koumine and its Anti-Allodynic Action in a Rat Model of Diabetic Neuropathic Pain. KM
29  2021 The implication of transient receptor potential canonical 6 in BDNF-induced mechanical allodynia in rat model of diabetic neuropathic pain. BDNF, DRG, PWMT, PWTL, STZ, TRPC6, TRPC6-AS
30  2021 The Modulatory Effect of Motor Cortex Astrocytes on Diabetic Neuropathic Pain. MCx, STZ
31  2021 The P2X7 Receptor Is Involved in Diabetic Neuropathic Pain Hypersensitivity Mediated by TRPV1 in the Rat Dorsal Root Ganglion. DRG, MWT, NPP, P2X7, SGCs, TRPV1, TWL
32  2021 Whole Genomic DNA Methylation Profiling of CpG Sites in Promoter Regions of Dorsal Root Ganglion in Diabetic Neuropathic Pain Mice. DRGs, KEGG, STZ, WGBS
33  2020 Activation of CaMKII and GluR1 by the PSD-95-GluN2B Coupling-Dependent Phosphorylation of GluN2B in the Spinal Cord in a Rat Model of Type-2 Diabetic Neuropathic Pain. CaMKII, PSD-95
34  2020 Acupuncture for diabetic neuropathic pain: A protocol for systematic review and meta analysis. GRADE
35  2020 Caveolin-1 in spinal cord modulates type-2 diabetic neuropathic pain through the Rac1/NOX2/NR2B signaling pathway. NOX, STZ
36  2020 Electroacupuncture alleviates diabetic neuropathic pain in rats by suppressing P2X3 receptor expression in dorsal root ganglia. DRG, EA, P2X3R
37  2020 Hydrogen sulfide attenuates diabetic neuropathic pain through NO/cGMP/PKG pathway and mu-opioid receptor. ---
38  2020 IL-35 promotes microglial M2 polarization in a rat model of diabetic neuropathic pain. HAPI, IL, LPS, MWT, rIL-35, TWL
39  2020 Kalirin-7 contributes to type 2 diabetic neuropathic pain via the postsynaptic density-95/N-methyl-D-aspartate receptor 2B-dependent N-methyl-D-aspartate receptor 2B phosphorylation in the spinal cord in rats. DM
40  2020 Long non coding RNAs involved in MAPK pathway mechanism mediates diabetic neuropathic pain. lncRNAs
41  2020 Predictors of worsening neuropathy and neuropathic pain after 12 years in people with HIV. BMI, DSP, QoL
42  2020 Relationship between diabetic neuropathic pain and comorbidity. Their impact on pain intensity, diabetes complications and quality of life in patients with type-2 diabetes mellitus. ---
43  2020 SIRT3 alleviates neuropathic pain by deacetylating FoxO3a in the spinal dorsal horn of diabetic model rats. CAT, FoxO3a, MnSOD, SIRT3, T2DM
44  2020 Sleep Characteristics in Diabetic Patients Depending on the Occurrence of Neuropathic Pain and Related Factors. DN4
45  2020 Spinal cannabinoid CB1 or CB2 receptors activation attenuates mechanical allodynia in streptozotocin-induced diabetic rats. ACEA
46  2020 Systematic Administration of B Vitamins Alleviates Diabetic Pain and Inhibits Associated Expression of P2X3 and TRPV1 in Dorsal Root Ganglion Neurons and Proinflammatory Cytokines in Spinal Cord in Rats. DRG, STZ
47  2020 TNF-alpha mediated upregulation of NaV1.7 currents in rat dorsal root ganglion neurons is independent of CRMP2 SUMOylation. CRMP2, DRG, TNF-alpha, TTX-S
48  2020 Upregulation of miR-133a-3p in the Sciatic Nerve Contributes to Neuropathic Pain Development. DM, mi, STZ
49  2019 Activation of GABAB Receptor Suppresses Diabetic Neuropathic Pain through Toll-Like Receptor 4 Signaling Pathway in the Spinal Dorsal Horn. GABAB, PWT, PWTL, TLR4
50  2019 Anxiety, depression and sleep disorders in patients with diabetic neuropathic pain: a systematic review. ---
51  2019 Catechol-O-methyltransferase polymorphism Val158Met is associated with distal neuropathic pain in HIV-associated sensory neuropathy. COMT, HIV-SN
52  2019 Cav-1 participates in the development of diabetic neuropathy pain through the TLR4 signaling pathway. Cav-1, NR2B, TLR4
53  2019 Dexmedetomidine attenuates P2X4 and NLRP3 expression in the spine of rats with diabetic neuropathic pain. DEX, DNP group, MNCV, MWT, N group, STZ, TEM
54  2019 Dexmedetomidine Reduces Diabetic Neuropathy Pain in Rats through the Wnt 10a/beta-Catenin Signaling Pathway. DEX, STZ
55  2019 Dihydromyricetin affects BDNF levels in the nervous system in rats with comorbid diabetic neuropathic pain and depression. BDNF, DHM, DP, TrkB
56  2019 Dihydromyricetin Alleviates Diabetic Neuropathic Pain and Depression Comorbidity Symptoms by Inhibiting P2X7 Receptor. DHM, DRGs, MDD
57  2019 Efficacy-Based Perspective to Overcome Reduced Opioid Analgesia of Advanced Painful Diabetic Neuropathy in Rats. 14-O-MeM6SU, MOR, NAL-M
58  2019 Identification of the Genome-wide Expression Patterns of Long Non-coding RNAs and mRNAs in Mice with Streptozotocin-induced Diabetic Neuropathic Pain. DE, lncRNA
59  2019 IL-35 alleviates inflammation progression in a rat model of diabetic neuropathic pain via inhibition of JNK signaling. DMSO, IL, ISI, JNK, qRT-PCR, STZ
60  2019 Infiltration of Blood-Derived Macrophages Contributes to the Development of Diabetic Neuropathy. MDMs
61  2019 Minocycline attenuates the development of diabetic neuropathy by modulating DREAM and BDNF protein expression in rat spinal cord. ---
62  2019 Progressive Increase of Inflammatory CXCR4 and TNF-Alpha in the Dorsal Root Ganglia and Spinal Cord Maintains Peripheral and Central Sensitization to Diabetic Neuropathic Pain in Rats. DRG, PWL, PWT
63  2019 Sirtuin 1 alleviates diabetic neuropathic pain by regulating synaptic plasticity of spinal dorsal horn neurons. GAP43, PSD-95, SIRT1
64  2019 Topical treatments for diabetic neuropathic pain. ---
65  2019 [Research Advances in Mitogen-activated Protein Kinases in Central and Peripheral Sensitization of Diabetic Neuropathic Pain]. ERK, MAPKs
66  2019 [The relationship between autophagy activation in spinal cord and type 2 diabetic neuropathic pain in rats]. LC3, MWT, STZ, TWL
67  2018 Activation of spinal dorsal horn P2Y13 receptors can promote the expression of IL-1β and IL-6 in rats with diabetic neuropathic pain. IL, STZ
68  2018 Ammoxetine attenuates diabetic neuropathic pain through inhibiting microglial activation and neuroinflammation in the spinal cord. JNK, MAPK, SNRIs, STZ, TCAs
69  2018 Effects of baicalin on diabetic neuropathic pain involving transient receptor potential vanilloid 1 in the dorsal root ganglia of rats. STZ, TRPV1
70  2018 Effects of palmatine on rats with comorbidity of diabetic neuropathic pain and depression. DP, IMFST, MWT, OFT, SPT, TWL
71  2018 Nanoparticle-Encapsulated Curcumin Inhibits Diabetic Neuropathic Pain Involving the P2Y12 Receptor in the Dorsal Root Ganglia. Cx43, DM, DRG, IL-1beta, p-Akt, SGCs
72  2018 Neuroprotective effect of tanshinone IIA against neuropathic pain in diabetic rats through the Nrf2/ARE and NF-kappaB signaling pathways. GSH-Px, HO-1, IkappaB, MDA, MWT, NCV, SOD, TSN, TWL
73  2018 Osthole alleviated diabetic neuropathic pain mediated by the P2X4 receptor in dorsal root ganglia. BDNF, DM, DRG, GFAP, IL-1beta, MWT, SGCs, TNF-alpha, TWL
74  2018 Safety and tolerability of lacosamide monotherapy in the elderly: A subgroup analysis from lacosamide trials in diabetic neuropathic pain. AEs
75  2018 The Effects of Agrin Isoforms on Diabetic Neuropathic Pain in a Rat Streptozotocin Model. ---
76  2017 Decreased spinal endomorphin-2 contributes to mechanical allodynia in streptozotocin-induced diabetic rats. EM2
77  2017 Effects of Duloxetine on the Toll-Like Receptor 4 Signaling Pathway in Spinal Dorsal Horn in a Rat Model of Diabetic Neuropathic Pain. ---
78  2017 Effects of electroacupuncture at 2 and 100 Hz on rat type 2 diabetic neuropathic pain and hyperalgesia-related protein expression in the dorsal root ganglion. CGRP, DRG, EA, FBG, FINS, ISI, PWL, STZ
79  2017 Effects of hyperbaric factors on lidocaine-induced apoptosis in spinal neurons and the role of p38 mitogen-activated protein kinase in rats with diabetic neuropathic pain. p38 MAPK
80  2017 Effects of LncRNA BC168687 siRNA on Diabetic Neuropathic Pain Mediated by P2X7 Receptor on SGCs in DRG of Rats. lncRNA, MWT, NO, TWL
81  2017 Effects of lncRNA uc.48+ siRNA on the release of CGRP in the spinal cords of rats with diabetic neuropathic pain. CGRP, FBG, lncRNA, MWT, SCs, TWL
82  2017 Endomorphin-2 Inhibition of Substance P Signaling within Lamina I of the Spinal Cord Is Impaired in Diabetic Neuropathic Pain Rats. DRG, EM2, IHC, MOR, NK1R, SDH, SP, WB
83  2017 Minocycline attenuates the development of diabetic neuropathy by inhibiting spinal cord Notch signaling in rat. i.p, MWT, STZ, TWL
84  2017 Nanoparticle-encapsulated emodin decreases diabetic neuropathic pain probably via a mechanism involving P2X3 receptor in the dorsal root ganglia. DM, DPN, DRG, mRNA, MWT, nano emodin, P2X3, T2DM, TWL
85  2017 The effect of sinomenine in diabetic neuropathic pain mediated by the P2X3 receptor in dorsal root ganglia. DM, DRG, MWT, T2DM, TWL
86  2017 The role of miR-190a-5p contributes to diabetic neuropathic pain via targeting SLC17A6. ---
87  2017 The Therapeutic Effect of Dexmedetomidine on Rat Diabetic Neuropathy Pain and the Mechanism. ELISA, IL, MWT, STZ, TNF, TWL
88  2017 [Current status of ion channels as drug targets for diabetic neuropathic pain]. ---
89  2017 [The mechanism of RvD1 alleviates type 2 diabetic neuropathic pain by influencing microglia polarization in rats]. Arg1, iNOS, MWT, STZ, T2DM, TWL
90  2016 Activation of ephrinB-EphB receptor signalling in rat spinal cord contributes to maintenance of diabetic neuropathic pain. IL, STZ, TNF
91  2016 Effects of curcumin on sodium currents of dorsal root ganglion neurons in type 2 diabetic neuropathic pain rats. DRG, T2DM, VGSCs
92  2016 lncRNA NONRATT021972 siRNA Decreases Diabetic Neuropathic Pain Mediated by the P2X3 Receptor in Dorsal Root Ganglia. DM, DRG, lncRNAs, mRNA, MWT, siRNA, T2DM, TNF-alpha, TWL
93  2016 LncRNA NONRATT021972 siRNA regulates neuropathic pain behaviors in type 2 diabetic rats through the P2X7 receptor in dorsal root ganglia. DM, DRG, lncRNAs, MWT, SGCs, siRNA, SNCV, TWL
94  2016 Pain modulation from the brain during diabetic neuropathy: Uncovering the role of the rostroventromedial medulla. RVM, TRPV1
95  2016 [The influence of lumbar sympathetic ganglion radiofrequency thermocoagulation on the activation of microglia in rats with diabetic neuropathic pain]. PWT, STZ
96  2015 Effects of curcumin on TTX-R sodium currents of dorsal root ganglion neurons in type 2 diabetic rats with diabetic neuropathic pain. DRG, T2DM, VGSCs
97  2015 Inhibition of spinal 5-HT3R reverted diabetes-induced mechanical hypersensitivity in a GABAAR-mediated neurotransmission-dependent manner. 5-HT3R, ERKs, GFAP, i.t, IBA-1, STZ
98  2015 LncRNA uc.48+ is involved in diabetic neuropathic pain mediated by the P2X3 receptor in the dorsal root ganglia. DM, DRG, lncRNAs, mRNA, MWT, RT-PCR, siRNA, TWL
99  2015 Predictors of new-onset distal neuropathic pain in HIV-infected individuals in the era of combination antiretroviral therapy. CHARTER
100  2015 Reduction of spinal glycine receptor-mediated miniature inhibitory postsynaptic currents in streptozotocin-induced diabetic neuropathic pain. GlyR, mIPSC, STZ