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Abbreviation : DXR
Long Form : doxorubicin
No. Year Title Co-occurring Abbreviation
2022 A mouse model for studying the effect of blood anti-PEG IgMs levels on the in vivo fate of PEGylated liposomes. i.p, PEG
2022 Circular RNA_ANKIB1 accelerates chemo-resistance of osteosarcoma via binding microRNA-26b-5p and modulating enhancer of zeste homolog 2. circ, EZH2, LRP, miR, MRP1
2022 Duration and dose of chemotherapy and dental development. ActD, CP, IF, VCR
2022 Effects of combined administration of doxorubicin and chloroquine on lung pathology in mice with solid Ehrlich ascites carcinoma. CAT, CQ, EAC, GPx, IHC, iNOS, MDA, NGAL, SOD
2022 Nano-Resveratrol: A Promising Candidate for the Treatment of Renal Toxicity Induced by Doxorubicin in Rats Through Modulation of Beclin-1 and mTOR. Card, KIM-1, N-Resv, RESV
2022 Oral administration of sodium bicarbonate can enhance the therapeutic outcome of Doxil® via neutralizing the acidic tumor microenvironment. ---
2022 Phytochemical Composition and Protective Effect of Vernonanthura polyanthes Leaf against In Vivo Doxorubicin-Mediated Toxicity. MN, NBF, VpLAE
2022 Prolonged oral antimicrobial administration prevents doxorubicin-induced loss of active intestinal stem cells. GF
2022 Rutin and Quercetin Counter Doxorubicin-Induced Liver Toxicity in Wistar Rats via Their Modulatory Effects on Inflammation, Oxidative Stress, Apoptosis, and Nrf2. ---
10  2022 Supplementing Soy-Based Diet with Creatine in Rats: Implications for Cardiac Cell Signaling and Response to Doxorubicin. ACC, AMPK, Cr, LVDP, SOY
11  2022 Systemic Anticancer Therapy Details and Dental Adverse Effects in Children. ActD, CP, VCR
12  2022 Toxicological and chemoprevention studies of Dalbergia ecastaphyllum (L.) Taub. stem, the botanical source of Brazilian red propolis. DEHE, DMH
13  2021 A Comparison of Doxorubicin-Resistant Colon Cancer LoVo and Leukemia HL60 Cells: Common Features, Different Underlying Mechanisms. ---
14  2021 Anti-inflammatory effects of saxagliptin and vildagliptin against doxorubicin-induced nephrotoxicity in rats: attenuation of NLRP3 inflammasome up-regulation and tubulo-interstitial injury. DPP4, IL-1beta, iNOS, NLRP3, SAX, TNF-alpha, VIL
15  2021 Betulinic acid exerts antigenotoxic and anticarcinogenic activities via inhibition of COX-2 and PCNA in rodents. BA, MN
16  2021 Cell surface Nucleolin represents a novel cellular target for neuroblastoma therapy. BM, NB, NCL
17  2021 Chemotherapy agents reduce protein synthesis and ribosomal capacity in myotubes independent of oxidative stress. CAs, Mzb, PTX, ROS
18  2021 CircPRDM2 Contributes to Doxorubicin Resistance of Osteosarcoma by Elevating EZH2 via Sponging miR-760. CCK-8, circPRDM2, circRNAs, EZH2, miR-760, OS, qRT-PCR, RIP
19  2021 CircSAMD4A contributes to cell doxorubicin resistance in osteosarcoma by regulating the miR-218-5p/KLF8 axis. circSAMD4A, KLF8, miR
20  2021 Circular RNA circPVT1 Contributes to Doxorubicin (DXR) Resistance of Osteosarcoma Cells by Regulating TRIAP1 via miR-137. ABCC1, Bcl-2, CCK-8, circRNA, miR-137, MRP-1, RIP, RT-qPCR, TRIAP1
21  2021 Circ_0001721 enhances doxorubicin resistance and promotes tumorigenesis in osteosarcoma through miR-758/TCF4 axis. CCK-8, OS, TCF4
22  2021 Down-regulation of circITCH promotes osteosarcoma development and resistance to doxorubicin via the miR-524/RASSF6 axis. circRNAs, OS, RASSF6
23  2021 Down-Regulation of Claudin-2 Expression by Cyanidin-3-Glucoside Enhances Sensitivity to Anticancer Drugs in the Spheroid of Human Lung Adenocarcinoma A549 Cells. C3G, CLDN2, P3G
24  2021 Doxorubicin Combined With Ifosfamide for Sarcoma Induces Muscle Atrophy and Sleep Disruption. IFM, STS
25  2021 Doxorubicin Embedded into Nanofibrillated Bacterial Cellulose (NFBC) Produces a Promising Therapeutic Outcome for Peritoneally Metastatic Gastric Cancer in Mice Models via Intraperitoneal Direct Injection. CMC, NFBC, PTX
26  2021 Epithelial Regeneration After Doxorubicin Arises Primarily From Early Progeny of Active Intestinal Stem Cells. DDR, IR
27  2021 Evaluation for pharmacokinetic exposure of cytotoxic anticancer drugs in elderly patients receiving (R-)CHOP therapy. AUCs, CPA, VCR
28  2021 Externally triggered smart drug delivery system encapsulating idarubicin shows superior kinetics and enhances tumoral drug uptake and response. IDA, SDDS
29  2021 HPLC with fluorescence detection for the bioanalysis and pharmacokinetic study of Doxorubicin and Prodigiosin loaded on eco-friendly casein nanomicelles in rat plasma. PDG
30  2021 Hsa_circ_0004674 promotes osteosarcoma doxorubicin resistance by regulating the miR-342-3p/FBN1 axis. circRNA, FBN1, OS
31  2021 Identification and characterization of a subpopulation of CD133+ cancer stem-like cells derived from SK-UT-1 cells. CSCs, ULMS
32  2021 Influence of Asiatic acid on cell proliferation and DNA damage in vitro and in vivo systems. AA
33  2021 LncRNA SNHG15 contributes to doxorubicin resistance of osteosarcoma cells through targeting the miR-381-3p/GFRA1 axis. GFRA1, SNHG15
34  2021 Loperamide potentiates doxorubicin sensitivity in triple-negative breast cancer cells by targeting MDR1 and JNK and suppressing mTOR and Bcl-2: In vitro and molecular docking study. DRI, LPR, MDR, TNBC
35  2021 Manool, a diterpene from Salvia officinalis, exerts preventive effects on chromosomal damage and preneoplastic lesions. NO
36  2021 MnSOD Lysine 68 acetylation leads to cisplatin and doxorubicin resistance due to aberrant mitochondrial metabolism. Ac, MEFs, MnSOD
37  2021 Modulating effect of DL-kavain on the mutagenicity and carcinogenicity induced by doxorubicin in Drosophila melanogaster. ETT, HB, SMART, ST
38  2021 Plasma proteome profiling of cardiotoxicity in patients with diffuse large B-cell lymphoma. CVD, DLBCL, IL-1RT1, SPON-1
39  2021 Potential of sperm small non-coding RNAs as biomarkers of testicular toxicity in a doxorubicin-induced mouse model. sncRNAs
40  2021 Preclinical toxicological study of long-circulating and fusogenic liposomes co-encapsulating paclitaxel and doxorubicin in synergic ratio. PTX
41  2021 Preventive activity of Copaifera langsdorffii Desf. leaves extract and its major compounds, afzelin and quercitrin, on DNA damage in in vitro and in vivo models. CLE, MMS
42  2021 Screening for Anticancer Activity of Leaf Ethanolic Extract of Alpinia elegans ("tagbak") on Human Cancer Cell Lines. 5-FU
43  2021 Selective anticancer effects of Serjania marginata Casar. extract in gastric cells are mediated by antioxidant response. ---
44  2021 Study Protocol: Phase I Dose Escalation Study of Oxaliplatin, Cisplatin and Doxorubicin Applied as PIPAC in Patients with Peritoneal Metastases. DLT, OXA, PIPAC
45  2021 Successful treatment of advanced pancreatic leiomyosarcoma treated with gemcitabine plus nab-paclitaxel: a case report and literature review. DOC, GEM, PLMS, PTX
46  2021 The Enhanced Efficacy of Intracellular Delivery of Doxorubicin/C6-Ceramide Combination Mediated by the F3 Peptide/Nucleolin System Is Supported by the Downregulation of the PI3K/Akt Pathway. CSC
47  2021 The role of exogenous epidermal growth factor on Ki-67 proliferation marker expression in the submandibular salivary gland of albino rats receiving doxorubicin. EGF
48  2021 The Utility of Intraventricular Pressure Gradient for Early Detection of Chemotherapy-Induced Subclinical Cardiac Dysfunction in Dogs. IVPG
49  2021 Transcription factor ELK1 accelerates aerobic glycolysis to enhance osteosarcoma chemoresistance through miR-134/PTBP1 signaling cascade. ---
50  2021 Upregulation of Chemoresistance by Mg2+ Deficiency through Elevation of ATP Binding Cassette Subfamily B Member 1 Expression in Human Lung Adenocarcinoma A549 Cells. ABCB1, ROS
51  2021 WNT/beta-Catenin Pathway in Soft Tissue Sarcomas: New Therapeutic Opportunities? STS
52  2020 Adjuvant Antitumor Immunity Contributes to the Overall Antitumor Effect of Pegylated Liposomal Doxorubicin (Doxil) in C26 Tumor-Bearing Immunocompetent Mice. ---
53  2020 Cancer During Pregnancy: The Role of Vascular Toxicity in Chemotherapy-Induced Placental Toxicity. EPI, PCNA, PW
54  2020 Chemotherapy-Induced Upregulation of Small Extracellular Vesicle-Associated PTX3 Accelerates Breast Cancer Metastasis. sEV
55  2020 Circular RNA hsa_circ_0003496 Contributes to Tumorigenesis and Chemoresistance in Osteosarcoma Through Targeting (microRNA) miR-370/Krüppel-Like Factor 12 Axis. CCK-8, circRNAs, KLF12, OS, qRT-PCR, RIP
56  2020 Decrease of the DXR-induced genotoxicity and nongenotoxic effects of Theobroma cacao revealed by micronucleus assay. MNPCEs, NEU, TCL
57  2020 Doxorubicin increases permeability of murine small intestinal epithelium and cultured T84 monolayers. ---
58  2020 Doxorubicin Inhibits Phosphatidylserine Decarboxylase and Modifies Mitochondrial Membrane Composition in HeLa Cells. PE, PS, PSD
59  2020 Effect of continuous saline bladder irrigation with concomitant single instillation of chemotherapy after transurethral resection on intravesical recurrence in patients with non-muscle-invasive bladder cancer. CSBI, IVR, NMIBC, SIC, TURBT
60  2020 Enhanced Expression of ABCB1 and Nrf2 in CD133-Positive Cancer Stem Cells Associates with Doxorubicin Resistance. CSCs
61  2020 In vitro hematotoxicity of Vernonanthura polyanthes leaf aqueous extract and its fractions. VpLAE
62  2020 Increase in Toxicity of Anticancer Drugs by PMTPV, a Claudin-1-Binding Peptide, Mediated via Down-Regulation of Claudin-1 in Human Lung Adenocarcinoma A549 Cells. CLDN1, LY
63  2020 Intravital imaging of liposome behavior upon repeated administration: A step towards the development of liposomal companion diagnostic for cancer nanotherapy. ML, NP
64  2020 Isolation and identification of adipose-derived stromal/stem cells from breast cancer patients after exposure neoadjuvant chemotherapy. 5-FU, ASCs, NAC
65  2020 Licochalcone A, a licorice flavonoid: antioxidant, cytotoxic, genotoxic, and chemopreventive potential. CHO, DMH, LicoA, MMS
66  2020 Mitofusin-2 mediates doxorubicin sensitivity and acute resistance in Jurkat leukemia cells. ETC, Mfn-2, OXPHOS, RCR
67  2020 MMP inhibitors attenuate doxorubicin cardiotoxicity by preventing intracellular and extracellular matrix remodelling. MMP-2
68  2020 Modulating effect of vitamin D3 on the mutagenicity and carcinogenicity of doxorubicin in Drosophila melanogaster and in silico studies. EcR, VD3
69  2020 Overcoming Wnt-beta-catenin dependent anticancer therapy resistance in leukaemia stem cells. LSCs
70  2020 Protective role of chrysin on doxorubicin-induced oxidative stress and DNA damage in rat testes. CAT, CR, MDA
71  2020 Resveratrol attenuates doxorubicin-induced meiotic failure through inhibiting oxidative stress and apoptosis in mouse oocytes. RES, ROS
72  2020 Sensitization of drug resistant sarcoma tumors by membrane modulation via short chain sphingolipid-containing nanoparticles. P-gp, SCSs
73  2020 Specific cellular internalization and pH-responsive behavior of doxorubicin loaded PLGA-PEG nanoparticles targeted with anti EGFRvIII antibody. DLE, EE, NPs, PVA, TEM
74  2020 TFAP2C-mediated LINC00922 signaling underpins doxorubicin-resistant osteosarcoma. lncRNAs, OS, TFAP2C
75  2020 The effects of melatonin and thymoquinone on doxorubicin-induced cardiotoxicity in rats. ---
76  2019 Anti-Tumor Effect of Inhibition of DNA Damage Response Proteins, ATM and ATR, in Endometrial Cancer Cells. ATM-Chk2, ATR-Chk1, DDR
77  2019 Chrysin enhances anticancer drug-induced toxicity mediated by the reduction of claudin-1 and 11 expression in a spheroid culture model of lung squamous cell carcinoma cells. CLDNs, PDK1, SCC
78  2019 Development of Long-Circulating and Fusogenic Liposomes Co-encapsulating Paclitaxel and Doxorubicin in Synergistic Ratio for the Treatment of Breast Cancer. CI, IC50, PTX
79  2019 Different sensitivities of senescent breast cancer cells to immune cell-mediated cytotoxicity. ---
80  2019 Increased myocardial 18F-FDG uptake as a marker of Doxorubicin-induced oxidative stress. H6PD, NB
81  2019 Isolation of senescent cells by iodixanol (OptiPrep) density gradient-based separation. HCC
82  2019 Levosimendan prevents doxorubicin-induced cardiotoxicity in time- and dose-dependent manner: implications for inotropy. BC, eNOS, L-NAME, LEVO, PLN
83  2019 Liposomes targeted to MHC-restricted antigen improve drug delivery and antimelanoma response. MAGE-A1, TCR
84  2019 Modification of fliposomes with a polycation can enhance the control of pH-induced release. ---
85  2019 Short and Long-Term Effects of the Exposure of Breast Cancer Cell Lines to Different Ratios of Free or Co-Encapsulated Liposomal Paclitaxel and Doxorubicin. BC, PTX
86  2019 Silymarin Enriched Extract (Silybum marianum) Additive Effect on Doxorubicin-Mediated Cytotoxicity in PC-3 Prostate Cancer Cells. SEE
87  2019 Synergistically Enhanced Inhibitory Effects of Pullulan Nanoparticle-Mediated Co-Delivery of Lovastatin and Doxorubicin to Triple-Negative Breast Cancer Cells. DS, FTIR, LV, PLV, TNBC
88  2019 Ten-year follow-up results of perioperative chemotherapy with doxorubicin and ifosfamide for high-grade soft-tissue sarcoma of the extremities: Japan Clinical Oncology Group study JCOG0304. IFM, PFS, STS
89  2019 Therapeutic effect of valsartan against doxorubicin-induced renal toxicity in rats. BUN, GPx, MDA, NO, NOS, SCr, SD, SOD
90  2019 Therapeutic Effects of Liraglutide, Oxytocin and Granulocyte Colony-Stimulating Factor in Doxorubicin-Induced Cardiomyopathy Model: An Experimental Animal Study. i.p
91  2018 Caffeic acid phenethyl ester potentiates gastric cancer cell sensitivity to doxorubicin and cisplatin by decreasing proteasome function. CAPE
92  2018 Chemoprotective effects of curcumin on doxorubicin-induced nephrotoxicity in wistar rats: by modulating inflammatory cytokines, apoptosis, oxidative stress and oxidative DNA damage. CMN
93  2018 Cocoplum (Chrysobalanus icaco L.) decreases doxorubicin-induced DNA damage and downregulates Gadd45a, Il-1beta, and Tnf-alpha in vivo. ---
94  2018 Complete genome sequence of Streptomyces peucetius ATCC 27952, the producer of anticancer anthracyclines and diverse secondary metabolites. DNR, NRPS
95  2018 Curcumin ameliorates doxorubicin-induced cardiotoxicity by abrogation of inflammation, apoptosis, oxidative DNA damage, and protein oxidation in rats. ---
96  2018 Decrease in paracellular permeability and chemosensitivity to doxorubicin by claudin-1 in spheroid culture models of human lung adenocarcinoma A549 cells. CLDN1, PI3K, ZO
97  2018 Disulfiram reduces metastatic osteosarcoma tumor burden in an immunocompetent Balb/c or-thotopic mouse model. DSF, Hi DSF, ICG, Lo DSF, OS
98  2018 Dose-dependent effects of frutalin on in vitro maturation and fertilization of pig oocytes. COCs, FTL, IVM
99  2018 Doxorubicin Expands in Vivo Secretion of Circulating Exosome in Mice. ---
100  2018 Doxorubicin-induced renal inflammation in rats: Protective role of Plantago major. MCP-1, P. major, TNF-alpha