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Abbreviation : DoE
Long Form : design of experiments
No. Year Title Co-occurring Abbreviation
2022 2,5-Diisopropenylthiophene by Suzuki-Miyaura cross-coupling reaction and its exploitation in inverse vulcanization: a case study. DIT, IVPs, MLR, S-r-DIT, SMCCR
2022 3D bioprinted microparticles: Optimizing loading efficiency using advanced DoE technique and machine learning modeling. 6-TG, DLE, DT, MP, PLpro, SMART
2022 A colloidal route to semiconducting tungsten disulfide nanosheets with monolayer thickness. TMDs
2022 A Convenient and Stable Heterogeneous Nickel Catalyst for Hydrodehalogenation of Aryl Halides Using Molecular Hydrogen. PBDE
2022 A Design of Experiments (DoE) Approach to Optimize Cryogel Manufacturing for Tissue Engineering Applications. ATP, ECM, RSM
2022 A high-resolution multi-attribute method for product characterization, process characterization, and quality control of therapeutic proteins. CEX, CQAs, DMB, MAM, QC, rCE-SDS
2022 A Multilayered, Lesion-Embedded Ultrasound Breast Phantom with Realistic Visual and Haptic Feedback for Needle Biopsy. TMMs
2022 A multivariate formulation and process development platform for direct compression. API, DC, T-PLS
2022 A new nanosuspension prepared with wet milling method for oral delivery of highly variable drug Cyclosporine A: development, optimization and in vivo evaluation. CsA, HPMC, PDI, PS, SDS, WM, ZP
10  2022 A proof of concept to define the parameters affecting poly-L-lactide-co-poly-ε-caprolactone shape memory electrospun nanofibers for biomedical applications. min, PLA, SEM
11  2022 A Response Surface Model to Predict and Experimentally Tune the Chemical, Magnetic and Optoelectronic Properties of Oxygen-Doped Boron Nitride. BN
12  2022 A Ribonucleotide ↔ Phosphoramidate Reaction Network Optimized by Computer-Aided Design. CLSM, cryo-TEM, DLS, EtIm
13  2022 An Optimalization Study on the Surface Texture and Machining Parameters of 60CrMoV18-5 Steel by EDM. ANOVA, GRA, MRR, SQ, TMRR, TWR, WL
14  2022 Application and Multi-Stage Optimization of Daylight Polymer 3D Printing of Personalized Medicine Products. API
15  2022 Application of Chemometry and Design of Experiments to Green HPTLC Method for Synchronous Estimation of Multiple FDCs of Cilnidipine. AQbD, AZL, CAAs, CIL, CLT, CMVs, FDCs, HPTLC, RP-HPLC
16  2022 Application of prediction intervals to the interpretation of the robustness study of a UHPLC method for the separation of cannabinoids. ---
17  2022 Application of Transmission Raman Spectroscopy in Combination with Partial Least-Squares (PLS) for the Fast Quantification of Paracetamol. API, PLS, RSD, TRS
18  2022 Artificial neural network (ANN) and response surface methodology (RSM) algorithm-based improvement, kinetics and isotherm studies of electrocoagulation of oily wastewater. ANN, ANOVA, RSM
19  2022 Artificial Neural Networks Elucidated the Essential Role of Mineral Nutrients versus Vitamins and Plant Growth Regulators in Achieving Healthy Micropropagated Plants. ANNs, PGRs
20  2022 Assessing the Relationships between Interdigital Geometry Quality and Inkjet Printing Parameters. DOD
21  2022 Assessment of Lipopeptide Mixtures Produced by Bacillus subtilis as Biocontrol Products against Apple Scab (Venturia inaequalis). ---
22  2022 Assessment of the Influence of Additives on the Mechanical Properties and Machinability of Al-11%Si Cast Alloys: Application of DOE and ANOVA Methods. ANOVA
23  2022 Automated Data Generation for Raman Spectroscopy Calibrations in Multi-Parallel Mini Bioreactors. CHO, mAb
24  2022 Bio-Herbicidal Potential of Nanoemulsions with Peppermint Oil on Barnyard Grass and Maize. PNs
25  2022 Bioactive Hydrolysates from Chlorella vulgaris: Optimal Process and Bioactive Properties. ---
26  2022 Chemometry and Green Chemistry-Based Chromatographic Analysis of Azilsartan Medoxomil, Cilnidipine and Chlorthalidone in Human Plasma Using Analytical Quality by Design Approach. AZM, CDP, CTD, FDCs, FFD, HPTLC
27  2022 Chitosan as a Functional Carrier for the Local Delivery Anti-Inflammatory Systems Containing Scutellariae baicalensis radix Extract. ---
28  2022 Chromatography Conditions Development by Design of Experiments for the Chemotype Differentiation of Four Bauhinia Species. PCA
29  2022 Critical factors influence on acidogenesis towards volatile fatty acid, biohydrogen and methane production from the molasses-spent wash. DOA, HAc, OL, VFAs
30  2022 Cubosomal Betamethasone-Salicylic Acid Nano Drug Delivery System for Enhanced Management of Scalp Psoriasis. BD, GMO, OF, PDI, SA, SCMC
31  2022 Degradation kinetics of artesunate for the development of an ex-tempore intravenous injection. alpha-DHA, beta-DHA, i.v, WHO
32  2022 Degradation of Benzotriazole UV Stabilizers in PAA/d-Electron Metal Ions Systems-Removal Kinetics, Products and Mechanism Evaluation. BUVs, UV-P
33  2022 Design and Investigation of a Photocatalytic Setup for Efficient Biotransformations Within Recombinant Cyanobacteria in Continuous Flow. ---
34  2022 Design and optimization of pH-sensitive Eudragit nanoparticles for improved oral delivery of triclabendazole. NPs
35  2022 Design of a novel switchable antibody display system in Pichia pastoris. PSD, scFvs, YSD
36  2022 Design of Experiment Approach to Modeling the Effects of Formulation and Drug Loading on the Structure and Properties of Therapeutic Nanogels. PDI
37  2022 Design of experiment techniques for the optimization of chromatographic analysis conditions: A review. ---
38  2022 Design of experiments approach to developing a robust ink for bioprinting. DMA, ECM
39  2022 Design of experiments as a decision tool for cell therapy manufacturing. AAV, IPEX, MOI, sgRNA
40  2022 Design of Experiments as a Tool to Optimize the Process of Coating Minitablets with Commercial Gastro-Resistant Coating Mixtures. MT, QbD
41  2022 Design of experiments meets immersive environment: Optimising eating atmosphere using artificial neural network. ANN, CCD, LUFS, PSO, RSM, VR
42  2022 Design of Experiments-Based Optimization of Flavonoids Extraction from Daphne genkwa Flower Buds and Flavonoids Contents at Different Blooming Stages. OPLS-DA, UHPLC-PDA-MS
43  2022 Design of Molecules with Low Hole and Electron Reorganization Energy Using DFT Calculations and Bayesian Optimization. DFT, GPR
44  2022 Design of Novel Nanoemulsion Formulations for Topical Ocular Delivery of Itraconazole: Development, Characterization and In Vitro Bioassay. BB, ITZ
45  2022 Design Space Approach for the Optimization of Green Fluidized Bed Granulation Process in the Granulation of a Poorly Water-Soluble Fenofibrate Using Design of Experiment. CQAs, DS, GFBG, QbD
46  2022 Destructive fibrotic teamwork: how both microenvironment stiffness and profibrotic interleukin 13 impair alveolar macrophage phenotype and function. IL-13
47  2022 Determination and Removal of Selected Pharmaceuticals and Total Organic Carbon from Surface Water by Aluminum Chlorohydrate Coagulant. ACH, AMO, COD, COL, DIC, EE, ERY, FLX, RSM, TOC, TSS
48  2022 Development and Optimization of Chitosan Nanoparticle-Based Intranasal Vaccine Carrier. BSA
49  2022 Development of a fibrin-mediated gene delivery system for the treatment of cystinosis via design of experiment. ---
50  2022 Development of a perfusion process for serum-free adenovirus vector herpes zoster vaccine production. CPPs, CQAs, CSVY, dpi, Fold, MOI, TOI, VZV
51  2022 Development of a solid phase microextraction gas chromatography tandem mass spectrometry methodology for the analysis of sixty personal care products in hydroalcoholic gels - hand sanitizers - in the context of COVID-19 pandemic. PCPs, RSD, SPME, WHO
52  2022 Development of alginate-spermidine micro/nanogels as potential antioxidant and anti-inflammatory tool in peripheral nerve injuries. Formulation studies and physico-chemical characterization. ALG, FTIR, PNI, SEM, SP
53  2022 Development of an animal component free production process for Sabin inactivated polio vaccine. ACF
54  2022 Development of Extended-Release Mini-Tablets Containing Metoprolol Supported by Design of Experiments and Physiologically Based Biopharmaceutics Modeling. BCS, FO, MS, PBBM, VBE
55  2022 Dissolution of Silk Fibroin in Mixtures of Ionic Liquids and Dimethyl Sulfoxide: On the Relative Importance of Temperature and Binary Solvent Composition. ILs, SF
56  2022 DoE-Based Analytical Failure Modes Critical Effect Analysis (AFMCEA) to a Multipurpose-RP-HPLC Method for the Estimation of Multiple FDC Products of Metformin Hydrochloride Using an Analytical Quality by Design Approach. AFMCEA, AQbD, FDCs, FMCEA, ICH, MODR, RP-HPLC, RPN
57  2022 DoE-derived continuous and robust process for manufacturing of pharmaceutical-grade wide-range LNPs for RNA-vaccine/drug delivery. LNP
58  2022 Dual-action of colloidal ISCOMs: an optimized approach using Box-Behnken design for the management of breast cancer. ISCOMs, NPY
59  2022 Effects of Graphene Oxide and Crumb Rubber on the Fresh Properties of Self-Compacting Engineered Cementitious Composite Using Response Surface Methodology. CR, EFNARC, GO-RECC, RSM, SC
60  2022 Efficiency of Tool Steel Cutting by Water Jet with Recycled Abrasive Materials. AWJ
61  2022 Electrospinning of Poly (Acrylamide), Poly (Acrylic Acid) and Poly (Vinyl Alcohol) Nanofibers: Characterization and Optimization Study on the Effect of Different Parameters on Mean Diameter Using Taguchi Design of Experiment Method. PAAm
62  2022 Establishment of Level a In Vitro-In Vivo Correlation (IVIVC) via Extended DoE-IVIVC Model: A Donepezil Case Study. AUC, IR, IVIVC, IVIVC, SR, Vmax
63  2022 Evaluation of extraction parameters in authentic hair reference material using statistical design of experiments. HRM
64  2022 Evaluation of Pretreatment and Extraction Parameters for the Analysis of Fentanyl in Hair Using Statistical Design of Experiments (DoE). HRM, SDS
65  2022 Exploring the Potential of Lactic Acid Fermentation for the Recovery of Exhausted Vanilla Beans. LAB
66  2022 Formation of Ciprofloxacin-Isonicotinic Acid Cocrystal Using Mechanochemical Synthesis Routes-An Investigation into Critical Process Parameters. APIs, CIP, HME, INCA
67  2022 Formulation Approaches for Improving the Dissolution Behavior and Bioavailability of Tolvaptan Using SMEDDS. BCS, PEG 200, QbD, SMEDDS
68  2022 Formulation design and optimization of cationic-charged liposomes of brimonidine tartrate for effective ocular drug delivery by design of experiment (DoE) approach. BRT, CDR, CQAs, PDI, PS, ZP
69  2022 Formulation Development of Doxycycline-Loaded Lipid Nanocarriers using Microfluidics by QbD Approach. DOXY, LN, RSM
70  2022 Formulation of a Gastroretentive In Situ Oral Gel Containing Metformin HCl Based on DoE. HEC, Met HCl, Sod ALG
71  2022 Fused Deposition Modeling Parameter Optimization for Cost-Effective Metal Part Printing. AM, FDM
72  2022 Fused-Filament Fabrication of Short Carbon Fiber-Reinforced Polyamide: Parameter Optimization for Improved Performance under Uniaxial Tensile Loading. FFF, ML
73  2022 Green Liquid Chromatography Method for the Determination of Related Substances Present in Olopatadine HCl Nasal Spray Formulation, Robustness by Design Expert. AGREE, GAPI, NMEI, OPT, QbD
74  2022 Highly Efficient One-Step Protein Immobilization on Polymer Membranes Supported by Response Surface Methodology. BSA, FTIR, PVDF, RSM, SEM, XPS
75  2022 Imipramine and olanzapine block apoE4-catalyzed polymerization of Aβ and show evidence of improving Alzheimer's disease cognition. AD, APOE, BBB, NACC
76  2022 Impact of Select Geometric and Operational Parameters on Hydrodynamics in Dissolution Apparatus 2 (Paddle Apparatus): A Design of Experiments Analysis Based on Computational Fluid Dynamics Simulations. CFD
77  2022 Impact of Vertical Blender Unit Parameters on Subsequent Process Parameters and Tablet Properties in a Continuous Direct Compression Line. BCH, CBD, EF, EV, FD, FRI, HUM, IMP, TBP, THR, TL, TL SD, TS, TT, TW
78  2022 Implementation of a Design of Experiments to Improve Periplasmic Yield of Functional ScFv Antibodies in a Phage Display Platform. ---
79  2022 Implementation of QbD Approach to the Analytical Method Development and Validation for the Estimation of Metformin Hydrochloride in Tablet Dosage Forms by HPLC. CAAs, CCD, CMPs, M-HCl, QbD
80  2022 Implementing the Design of Experiments (DoE) Concept into the Development Phase of Orodispersible Minitablets (ODMTs) Containing Melatonin. CQAs, ODMTs
81  2022 Importance of Build Design Parameters to the Fatigue Strength of Ti6Al4V in Electron Beam Melting Additive Manufacturing. LoF, PBF, XCT
82  2022 Improved Artificial Neural Network Training Based on Response Surface Methodology for Membrane Flux Prediction. ANN, FFNN, FFNN, GDM, LM, RSM
83  2022 Indirect optimization of staphylokinase expression level in dicistronic auto-inducible system. SAK
84  2022 Insights into selective hydrogenation of levulinic acid using copper on manganese oxide octahedral molecular sieves. GVL, LA
85  2022 Investigation and Optimization of Vacuum Plasma Treatment of PA66 Fabric for Reduced Fire Retardant Consumption. FR, LOI, MW
86  2022 Investigation of an artifact during non-reduced capillary electrophoresis with sodium dodecyl sulfate analysis utilizing N-ethylmaleimide as an alkylation reagent. NEM, nrCE-SDS
87  2022 Is It Possible to Improve the Bioavailability of Resveratrol and Polydatin Derived from Polygoni cuspidati Radix as a Result of Preparing Electrospun Nanofibers Based on Polyvinylpyrrolidone/Cyclodextrin? ---
88  2022 Luliconazole Nail Lacquer for the Treatment of Onychomycosis: Formulation, Characterization and In Vitro and Ex Vivo Evaluation. AFM, DSC, LCZ-NL, SEM, XRD
89  2022 Maximization of the Minicircle DNA Vaccine Production Expressing SARS-CoV-2 RBD. LB, mcDNA, PP, RBD, SARS-CoV-2, TB
90  2022 Maximizing the recovery of the native p28 bacterial peptide with improved activity and maintained solubility and stability in Escherichia coli BL21 (DE3). CPP, RSM
91  2022 Mechanisms, toxicity and optimal conditions - research on the removal of benzotriazoles from water using Wolffia arrhiza. 1H-BTR, 4MBTR, 5Cl-BTR, 5M-BTR, BTRs
92  2022 Mediating bio-fate of polymeric cholecalciferol nanoparticles through rational size control. FNP
93  2022 Melatonin loaded hybrid nanomedicine: DoE approach, optimization and in vitro study on diabetic retinopathy model. MEL, mel-LPHNs
94  2022 Metronidazole nanosuspension loaded dissolving microarray patches: An engineered composite pharmaceutical system for the treatment of skin and soft tissue infection. MAPs, MTZ, MTZ-NS, SSTI
95  2022 Microfluidic Manufacturing of Liposomes: Development and Optimization by Design of Experiment and Machine Learning. AI, ANN, FRR, PDI, TFR
96  2022 Microfluidic Paper-Based Blood Plasma Separation Device as a Potential Tool for Timely Detection of Protein Biomarkers. BPS, PAD, SEM
97  2022 Micrometric DNA/PEI polyplexes correlate with higher transient gene expression yields in HEK 293 cells. PEI
98  2022 Microwave-Assisted Extraction of Polyphenols from Blackcurrant By-Products and Possible Uses of the Extracts in Active Packaging. ANOVA, CCO
99  2022 Model-Based Product Temperature and Endpoint Determination in Primary Drying of Lyophilization Processes. ---
100  2022 Modelling the Compaction Step of a Platform Direct Compression Process. ---