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Abbreviation : EHs
Long Form : epoxide hydrolases
No. Year Title Co-occurring Abbreviation
2021 EPHX1 mutations cause a lipoatrophic diabetes syndrome due to impaired epoxide hydrolysis and increased cellular senescence. KO
2021 Relative Importance of Soluble and Microsomal Epoxide Hydrolases for the Hydrolysis of Epoxy-Fatty Acids in Human Tissues. EH3, EpFAs, mEH, sEH
2020 An epoxide hydrolase from endophytic Streptomyces shows unique structural features and wide biocatalytic activity. ---
2020 Identification and catalytic properties of new epoxide hydrolases from the genomic data of soil bacteria. LEHs
2020 Mutation of an atypical oxirane oxyanion hole improves regioselectivity of the α/β-fold epoxide hydrolase Alp1U. ---
2020 Nearly perfect kinetic resolution of racemic o-nitrostyrene oxide by AuEH2, a microsomal epoxide hydrolase from Aspergillus usamii, with high enantio- and regio-selectivity. ---
2020 The Multifaceted Role of Epoxide Hydrolases in Human Health and Disease. ---
2019 The molecular structure of an epoxide hydrolase from Trichoderma reesei in complex with urea or amide-based inhibitors. TrEH
2018 New Thermophilic alpha/beta Class Epoxide Hydrolases Found in Metagenomes From Hot Environments. ---
10  2018 Substrate and inhibitor selectivity, and biological activity of an epoxide hydrolase from Trichoderma reesei. ---
11  2017 Arabidopsis thaliana EPOXIDE HYDROLASE1 (AtEH1) is a cytosolic epoxide hydrolase involved in the synthesis of poly-hydroxylated cutin monomers. AtEH1, EGFP
12  2017 Enantioconvergent hydrolysis of racemic styrene oxide at high concentration by a pair of novel epoxide hydrolases into (R)-phenyl-1,2-ethanediol. aTOF, rac-SO, VrEH3
13  2017 In Vitro Metabolism of Oprozomib, an Oral Proteasome Inhibitor: Role of Epoxide Hydrolases and Cytochrome P450s. DDIs, mEH, sEH
14  2017 Structure of a soluble epoxide hydrolase identified in Trichoderma reesei. TrEH
15  2016 Data set of optimal parameters for colorimetric red assay of epoxide hydrolase activity. ---
16  2016 Epoxide hydrolase of Trichoderma reesei: Biochemical properties and conformational characterization. ---
17  2016 Exported Epoxide Hydrolases Modulate Erythrocyte Vasoactive Lipids during Plasmodium falciparum Infection. EETs, PfEH1, RBCs
18  2016 Ingestion of the epoxide hydrolase inhibitor AUDA modulates immune responses of the mosquito, Culex quinquefasciatus during blood feeding. ---
19  2016 Rational Design of Potent and Selective Inhibitors of an Epoxide Hydrolase Virulence Factor from Pseudomonas aeruginosa. CFTR
20  2015 Discovery and characterization of thermophilic limonene-1,2-epoxide hydrolases from hot spring metagenomic libraries. LEH
21  2015 Efficient kinetic resolution of phenyl glycidyl ether by a novel epoxide hydrolase from Tsukamurella paurometabola. PGE
22  2015 Gene-environment interactions in esophageal cancer. EC, GSTs, NATs, SULTs, UGTs
23  2015 Optimization of translation profiles enhances protein expression and solubility. ---
24  2015 Polycyclic aromatic hydrocarbons: from metabolism to lung cancer. AhR, AKRs, NQOs, PAHs
25  2014 Expression and characterization of an epoxide hydrolase from Anopheles gambiae with high activity on epoxy fatty acids. 14,15-EET, AgEH, JHEHs
26  2014 Trigger factor assisted folding of the recombinant epoxide hydrolases identified from C. pelagibacter and S. nassauensis. BGE, e.e.p, MSO, TF
27  2013 Cloning and characterization of a microsomal epoxide hydrolase from Heliothis virescens. JHEHs, JHs
28  2013 Cross-linked enzyme aggregates of Mung bean epoxide hydrolases: a highly active, stable and recyclable biocatalyst for asymmetric hydrolysis of epoxides. CLEAs
29  2013 Heterologous overexpression of Vigna radiata epoxide hydrolase in Escherichia coli and its catalytic performance in enantioconvergent hydrolysis of p-nitrostyrene oxide into (R)-p-nitrophenyl glycol. pNPG, pNSO, RACE
30  2013 Predictive model for epoxide hydrolase-generated stereochemistry in the biosynthesis of nine-membered enediyne antitumor antibiotics. KED, NCS
31  2011 QM/MM study of the mechanism of enzymatic limonene 1,2-epoxide hydrolysis. LEH, QM/MM
32  2009 Biochemical characterization and transcriptional analysis of the epoxide hydrolase from white-rot fungus Phanerochaete chrysosporium. ---
33  2008 A cell-based adrenaline assay for automated high-throughput activity screening of epoxide hydrolases. ---
34  2008 An epoxide hydrolase involved in the biosynthesis of an insect sex attractant and its use to localize the production site. HDL
35  2008 Multi-copy expression and fed-batch production of Rhodotorula araucariae epoxide hydrolase in Yarrowia lipolytica. EH
36  2007 Biosynthesis of (R)-phenyl-1,2-ethanediol from racemic styrene oxide by using bacterial and marine fish epoxide hydrolases. ---
37  2006 Cloning of an epoxide hydrolase-encoding gene from Rhodotorula mucilaginosa and functional expression in Yarrowia lipolytica. ---
38  2005 Comparative metabolism of methacrylonitrile and acrylonitrile to cyanide using cytochrome P4502E1 and microsomal epoxide hydrolase-null mice. AN, MAN, WT
39  2005 EHPred: an SVM-based method for epoxide hydrolases recognition and classification. AAC, DPC, MCC, PAAC, SVMs
40  2005 Epoxide hydrolases: mechanisms, inhibitor designs, and biological roles. ---
41  2005 Epoxide hydrolases: their roles and interactions with lipid metabolism. ---
42  2003 Characterization and cDNA cloning of a clofibrate-inducible microsomal epoxide hydrolase in Drosophila melanogaster. DmEH
43  2002 Stereochemical features of the hydrolysis of 9,10-epoxystearic acid catalysed by plant and mammalian epoxide hydrolases. ---
44  2001 Monitoring expression of genes involved in drug metabolism and toxicology using DNA microarrays. 3-MC, GSTs, STs, UGTs
45  2000 Development of phase II xenobiotic metabolizing enzymes in differentiating murine clara cells. GSTs
46  1997 The role of human glutathione transferases and epoxide hydrolases in the metabolism of xenobiotics. GSTs, mEH, sEH
47  1995 Improved radiolabeled substrates for soluble epoxide hydrolase. sEH, TSO
48  1985 Interindividual variations in the activities of cytosolic and microsomal epoxide hydrolase in human liver. EHm
49  1983 Radiometric assays for mammalian epoxide hydrolases and glutathione S-transferase. ---