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Abbreviation : FDX1
Long Form : ferredoxin 1
No. Year Title Co-occurring Abbreviation
2023 EREG is the core onco-immunological biomarker of cuproptosis and mediates the cross-talk between VEGF and CD99 signaling in glioblastoma. CCK-8, CuAS, EdU, EREG, GBM, IF, IHC, Olig1, PCA, PD-L1, qRT-PCR, scRNA-seq, VEGFA, WB
2023 Ferredoxin 1 regulates granulosa cell apoptosis and autophagy in polycystic ovary syndrome. PCOS
2023 Multi-omics pan-cancer study of cuproptosis core gene FDX1 and its role in kidney renal clear cell carcinoma. GTEx, KIRC, MSI, TCA, TIDE, TMB
2023 SP1 impacts the primordial to primary follicle transition by regulating cholesterol metabolism in granulosa cells. GCs, PPT
2022 A Novel Cuprotosis-Related Gene FDX1 Signature for Overall Survival Prediction in Clear Cell Renal Cell Carcinoma Patients. IHC, qRT-PCR, WB
2022 Characterization of the functional effects of ferredoxin 1 as a cuproptosis biomarker in cancer. GTEx
2022 Cuproptosis, the novel therapeutic mechanism for heart failure: a narrative review. HF
2022 Cuproptosis-related gene FDX1 expression correlates with the prognosis and tumor immune microenvironment in clear cell renal cell carcinoma. ccRCC, GSEA, OS
2022 Cuproptosis-Related Risk Score Predicts Prognosis and Characterizes the Tumor Microenvironment in Hepatocellular Carcinoma. AUC, BRCA1, CRRS, CTNNB1, HCC, LASSO, OS, TACE, TP53
10  2022 FDX1 expression predicts favourable prognosis in clear cell renal cell carcinoma identified by bioinformatics and tissue microarray analysis. ccRCC
11  2022 Ferredoxin 1 is a cuproptosis-key gene responsible for tumor immunity and drug sensitivity: A pan-cancer analysis. MMR, MSI, TMB, TME
12  2021 Identification of novel genes and pathways regulated by the orphan nuclear receptor COUP-TFII in mouse MA-10 Leydig cells†. Cyp11a1, GST-a3, HSD3B1, INHA, INSL3, PRLR, Scarb1
13  2021 Phosphorylated protein modification analysis on normal liver and Exo-celiac liver of Glyptosternum maculatum. DDX51, DEPs, LIMCH1, PPI
14  2020 Calcitriol increases frataxin levels and restores mitochondrial function in cell models of Friedreich Ataxia. FA
15  2020 FDXR regulates TP73 tumor suppressor via IRP2 to modulate aging and tumor suppression. FDXR, IRP2, MEFs, WT
16  2017 Evolution of Chlamydomonas reinhardtii ferredoxins and their interactions with [FeFe]-hydrogenases. ---
17  2017 Role of protein-glutathione contacts in defining glutaredoxin-3 [2Fe-2S] cluster chirality, ligand exchange and transfer chemistry. Grx
18  2017 Transcription factors SF1 and cJUN cooperate to activate the Fdx1 promoter in MA-10 Leydig cells. ---
19  2016 Human Mitochondrial Ferredoxin 1 (FDX1) and Ferredoxin 2 (FDX2) Both Bind Cysteine Desulfurase and Donate Electrons for Iron-Sulfur Cluster Biosynthesis. ACP, FDX2
20  2015 Ferredoxin 1b (Fdx1b) Is the Essential Mitochondrial Redox Partner for Cortisol Biosynthesis in Zebrafish. Fdx1b
21  2013 Transcriptional regulation of human ferredoxin 1 in ovarian granulosa cells. hMSCs, SF-1
22  2011 Both human ferredoxins 1 and 2 and ferredoxin reductase are important for iron-sulfur cluster biogenesis. ---
23  1998 Assignment of ferredoxin 1 (FDX1) to bovine chromosome 15 with somatic cell hybrids. ---