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Abbreviation : FTH
Long Form : ferritin heavy chain
No. Year Title Co-occurring Abbreviation
2022 1,3-Dichloro-2-propanol induced ferroptosis through Nrf2/ARE signaling pathway in hepatocytes. 1,3-DCP, ACSL4, FPN, GPX4, HO-1, MDA, Nrf2, ROS
2022 Artemether attenuates renal tubular injury by regulating iron metabolism in mice with streptozotocin-induced diabetes. FTL, STZ, T1D
2022 Counteraction of Myocardial Ferritin Heavy Chain Deficiency by Heme Oxygenase-1. HO-1
2022 Dexmedetomidine post-conditioning alleviates myocardial ischemia-reperfusion injury in rats by ferroptosis inhibition via SLC7A11/GPX4 axis activation. COX-2, DEX, GPX4, IRI, ROS
2022 Effect of iron overload on endothelial cell calcification and its mechanism. Bad, Bax, BMP-2, DFO, DMT1, FTL, MDA, MGP, qPCR, ROS
2022 Enhanced ROS-Boosted Phototherapy against Pancreatic Cancer via Nrf2-Mediated Stress-Defense Pathway Suppression and Ferroptosis Induction. Ce6, GPX4, HSPs, Nrf2, PDA, PDT, PEG-FA, PTT, ROS
2022 Exosomes derived from pericardial adipose tissues attenuate cardiac remodeling following myocardial infarction by Adipsin-regulated iron homeostasis. MI, TFRC
2022 Exposure to low-dose cadmium induces testicular ferroptosis. Cd, MDA
2022 Functional consequence of myeloid ferritin heavy chain on acute and chronic effects of rhabdomyolysis-induced kidney injury. AKI
10  2022 Ginsenoside Rg1 ameliorates sepsis-induced acute kidney injury by inhibiting ferroptosis in renal tubular epithelial cells. AKI, BUN, CLP, FSP1, FTL, GPX4, MDA, SCr, SI-AKI, TECs
11  2022 Hepcidin Alleviates LPS-Induced ARDS by Regulating the Ferritin-Mediated Suppression of Ferroptosis. ARDS, Fer-1, LPS, TfR1
12  2022 High Iron Exposure from the Fetal Stage to Adulthood in Mice Alters Lipid Metabolism. ---
13  2022 Inhibition of CISD2 promotes ferroptosis through ferritinophagy-mediated ferritin turnover and regulation of p62-Keap1-NRF2 pathway. CISD2, HO-1, Nrf2, ROS
14  2022 Interplay of Ferritin Accumulation and Ferroportin Loss in Ageing Brain: Implication for Protein Aggregation in Down Syndrome Dementia, Alzheimer's, and Parkinson's Diseases. AD, DMT1, DS, HD, PD
15  2022 Neurofilament Light Chain (NF-L) Stimulates Lipid Peroxidation to Neuronal Membrane through Microglia-Derived Ferritin Heavy Chain (FTH) Secretion. NfL
16  2022 PM2 .5 exposure-induced ferroptosis in neuronal cells via inhibiting ERK/CREB pathway. Fer-1, FTL, GPX4, N2a, TFRC
17  2022 Self-recovery study of fluoride-induced ferroptosis in the liver of zebrafish (Danio rerio). dpf, FPN, GPX4, MDA, ROS, slc7a11, Tf, TfR
18  2021 Ferritin disorder in the plasma and hippocampus associated with major depressive disorder. BDNF, FTL, HC, MDD
19  2021 FTH promotes the proliferation and renders the HCC cells specifically resist to ferroptosis by maintaining iron homeostasis. HCC, MMP, ROS
20  2021 Fusaricide is a Novel Iron Chelator that Induces Apoptosis through Activating Caspase-3. FCD, NSCLC, TfR1
21  2021 New Insights into the Role of Ferritin in Iron Homeostasis and Neurodegenerative Diseases. AD, FTL, NF, PD
22  2021 Transcriptional Repression of Ferritin Light Chain Increases Ferroptosis Sensitivity in Lung Adenocarcinoma. 4-HNE, FOXA1, FTL, LUAD, TFCP2, TFRC, YAP
23  2020 Amentoflavone suppresses cell proliferation and induces cell death through triggering autophagy-dependent ferroptosis in human glioma. AF, LDH
24  2020 Dual-Effect of Magnetic Resonance Imaging Reporter Gene in Diagnosis and Treatment of Hepatocellular Carcinoma. AFP, HCC, T2WI, Tf-LP, TfR
25  2020 Exercise Training and Vitamin C Supplementation Affects Ferritin mRNA in Leukocytes without Affecting Prooxidative/Antioxidative Balance in Elderly Women. FTL
26  2020 FtH-Mediated ROS Dysregulation Promotes CXCL12/CXCR4 Axis Activation and EMT-Like Trans-Differentiation in Erythroleukemia K562 Cells. EMT, NAC, ROS
27  2020 Heme oxygenase 1 protects human colonocytes against ROS formation, oxidative DNA damage and cytotoxicity induced by heme iron, but not inorganic iron. CRC, HCEC, HO-1, ROS
28  2020 Hypoxia inhibits ferritinophagy, increases mitochondrial ferritin, and protects from ferroptosis. JNK, NCOA4
29  2020 Impaired Postnatal Myelination in a Conditional Knockout Mouse for the Ferritin Heavy Chain in Oligodendroglial Cells. OPCs
30  2020 Knockdown of ferritin heavy chain (FTH) inhibits the migration of prostate cancer through reducing S100A4, S100A2, and S100P expression. GO, iTRAQ, PCa
31  2020 Peritumoral administration of IFNbeta upregulated mesenchymal stem cells inhibits tumor growth in an orthotopic, immunocompetent rat glioma model. IFNbeta-FTH-MSCs, MSCs
32  2019 Disrupted Iron Storage in Dental Fluorosis. ---
33  2019 Ferritin Light Chain Confers Protection Against Sepsis-Induced Inflammation and Organ Injury. CLP
34  2019 Ferritin: A potential serum marker for lymph node metastasis in head and neck squamous cell carcinoma. FTL, GEO, HNSCC, SF
35  2019 Iron and Ferritin Modulate MHC Class I Expression and NK Cell Recognition. MEFs, MHC, NK
36  2019 Iron Dyshomeostasis Participated in Rat Hippocampus Toxicity Caused by Aluminum Chloride. Al, DMT1, FPN1, IRP2
37  2019 Iron Metabolism in the Peripheral Nervous System: The Role of DMT1, Ferritin, and Transferrin Receptor in Schwann Cell Maturation and Myelination. DMT1, SC, SCs, Tfr1
38  2019 Screening, identification of prostate cancer urinary biomarkers and verification of important spots. BPH, FTL, MS, PCa, PSA, sh
39  2018 Ferritin H Deficiency in Myeloid Compartments Dysregulates Host Energy Metabolism and Increases Susceptibility to Mycobacterium tuberculosis Infection. Mtb
40  2017 Association of ferritin with prostate cancer. BPH, FCR, FTL, PCa, PSA
41  2017 Expression of Iron-Related Proteins Differentiate Non-Cancerous and Cancerous Breast Tumors. BMP6, CD74, ELISA, FPN, FTL, HMGB1, INHA, MyD88, RPPA, STAT3, STAT5, TFRC
42  2017 In Vivo Long-Term Tracking of Neural Stem Cells Transplanted into an Acute Ischemic Stroke model with Reporter Gene-Based Bimodal MR and Optical Imaging. EGFP, FLI, MRI, NSCs
43  2017 In vivo tracking of the tropism of mesenchymal stem cells to malignant gliomas using reporter gene-based MR imaging. EGFP, FTH-MSCs, MRI, MSCs
44  2017 Protoporphyrin IX regulates peripheral benzodiazepine receptor associated protein 7 (PAP7) and divalent metal transporter 1 (DMT1) in K562 cells. DMT1, IRE, PAP7, PAP7, PBR, PpIX, TfR1
45  2017 Reabsorption of iron into acutely damaged rat liver: A role for ferritins. FTL, TAA
46  2016 Ferroportin mRNA is down-regulated in granulosa and cervical cells from infertile women. FTL, TFRC
47  2016 Influence of the availability of iron during hypoxia on the genes associated with apoptotic activity and local iron metabolism in rat H9C2cardiomyocytes and L6G8C5skeletal myocytes. AFC, DFO, FPN1
48  2016 MR molecular imaging of tumours using ferritin heavy chain reporter gene expression mediated by the hTERT promoter. hTERT
49  2016 The Effects of Dietary Fat and Iron Interaction on Brain Regional Iron Contents and Stereotypical Behaviors in Male C57BL/6J Mice. ---
50  2015 Cytoprotective effects of ferritin on doxorubicin-induced breast cancer cell death. FTL, ROS
51  2015 In vivo Tracking of Dendritic Cell using MRI Reporter Gene, Ferritin. DCs, GFP, LNs, MRI
52  2014 Noninvasive MRI and multilineage differentiation capability of ferritin-transduced human mesenchymal stem cells. GFP, hMSCs, IL-5, OCT4, TNF-alpha
53  2014 Significance of ferritin expression in formation of malignant phenotype of human breast cancer cells. BC, ROS, SOD
54  2014 The effect of anti-inflammatory properties of ferritin light chain on lipopolysaccharide-induced inflammatory response in murine macrophages. FTL, IL-1beta, LIP, LPS, NF-kappaB, NO, PGE2, ROS, TNF-alpha
55  2013 Iron deposition and ferritin heavy chain (Fth) localization in rodent teeth. ---
56  2013 Noninvasive identification of viable cell populations in docetaxel-treated breast tumors using ferritin-based magnetic resonance imaging. BCSCs, CSCs, EGFP, MRI
57  2013 Proximal tubule H-ferritin mediates iron trafficking in acute kidney injury. AKI, FPN
58  2012 Ferritin heavy chain is the host factor responsible for HCV-induced inhibition of apoB-100 production and is required for efficient viral infection. HCV, HCVcc
59  2012 Regulation of iron-related molecules in the rat hippocampus: sex- and age-associated differences. ASN, F344BN, HO1, IRP1
60  2010 Evaluation of ferritin-overexpressing brain in newly developed transgenic mice. Tg
61  2010 Iron state in association with retinoid metabolism in non-alcoholic fatty liver disease. ADH1, CYP26A1, FPN, HEPC, HJV, NAFLD, NEO, ROS, SS
62  2009 Noninvasive monitoring of embryonic stem cells in vivo with MRI transgene reporter. ES, mES, MRI, TFRC
63  2008 HBx modulates iron regulatory protein 1-mediated iron metabolism via reactive oxygen species. HBx, Huh7-HBx, IRP1, LIP, NAc, ROS, TfR1
64  2006 Oxidative stress in the aging murine olfactory bulb: redox proteomics and cellular localization. ALDO1, OBs
65  2002 PLIF, a novel human ferritin subunit from placenta with immunosuppressive activity. ---
66  1993 Differential processing of the ferritin heavy chain mRNA in human liver and adult human brain. ---