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Abbreviation : Fis1
Long Form : fission 1
No. Year Title Co-occurring Abbreviation
2022 Hyperglycemia aggravates ischemic brain damage via ERK1/2 activated cell autophagy and mitochondrial fission. DM, I/R, STZ
2022 Long-term cadmium exposure impairs cognitive function by activating lnc-Gm10532/m6A/FIS1 axis-mediated mitochondrial fission and dysfunction. ATP, Cd, lnc-Gm10532, METTL14, ROS
2022 Lycopene alleviates multiple-mycotoxin-induced toxicity by inhibiting mitochondrial damage and ferroptosis in the mouse jejunum. AFB1, DON, FTH1, GPX4, LYC, MDA, Mfn1, ROS, SLC3A2, T-AOC, TfR1, ZEN, ZO-1
2022 Paeoniflorin Alleviates Skeletal Muscle Atrophy in Ovariectomized Mice through the ERalpha/NRF1 Mitochondrial Biogenesis Pathway. ERalpha, Mfn1, Mfn2, MYH3, MyoG, NRF1, PNF, TNF-alpha
2022 PRDX1 Influences The Occurrence and Progression of Liver Cancer by Inhibiting Mitochondrial Apoptosis Pathway. Bcl-2, Drp1, Dyn2, qRT-PCR
2022 The Role of Mitochondrial Dynamic Dysfunction in Age-Associated Type 2 Diabetes. Drp1, Mfn1, Mfn2, mtDNA, OPA1
2021 Abnormal Mitochondria-Endoplasmic Reticulum Communication Promotes Myocardial Infarction. BAP31, JNK, mtROS
2021 Abscisic acid suppresses the activation of NLRP3 inflammasome and oxidative stress in murine allergicairwayinflammation. ABA, Drp1, Mfn2, OPA1
2020 Apolipoprotein E negatively regulates murine allergic airway inflammation via suppressing the activation of NLRP3 inflammasome and oxidative stress. AHR, APOE, BALF, Drp1, HDM, Mfn2, OPA1, OVA, WT
10  2020 Cdk5-mediated Drp1 phosphorylation drives mitochondrial defects and neuronal apoptosis in radiation-induced optic neuropathy. Cdk5, Drp1, EBRT, RION, ROS
11  2020 Deletion of Bmal1 Impairs Pancreatic beta-Cell Function via Mitochondrial Signaling Pathway. BMAL1, Mfn1, Mfn2, siRNA
12  2020 Heat stress induces apoptosis through disruption of dynamic mitochondrial networks in dairy cow mammary epithelial cells. Cyto-c, DCMECs, Drp1, Opa-1
13  2020 Impact of neural stem cell-derived extracellular vesicles on mitochondrial dysfunction, sirtuin 1 level, and synaptic deficits in Alzheimer's disease. AD, EVs, GAP43, MAP2, NRF1 and 2, NSC, PGC1alpha, PSD-95, SIRT1, SYP, Tg
14  2019 Ablation of TMEM126B protects against heart injury via improving mitochondrial function in high fat diet (HFD)-induced mice. Drp1, HFD, Mfn1, PA, ROS, TMEM126B, WT
15  2019 Drp1/Fis1 interaction mediates mitochondrial dysfunction in septic cardiomyopathy. Drp1, EM, LPS
16  2019 Interval and continuous exercise overcome memory deficits related to beta-Amyloid accumulation through modulating mitochondrial dynamics. CAT, Drp1, HIIT, MDA, Mfn1, Mfn2, MICT, OPA1, ROS, SOD
17  2019 Selective brain hypothermia-induced neuroprotection against focal cerebral ischemia/reperfusion injury is associated with Fis1 inhibition. ---
18  2019 [Effects of uncoupling protein 2 overexpression on myocardial mitochondrial dynamics in sepsis rats]. AAV, ATP, CLP, Drp1, LVAWd, LVAWs, LVEDd, LVEDs, LVEDV, LVEF, LVESV, LVFS, LVM, LVPWd, LVPWs, OPA1, SD, Sham group, SV, UCP2, UCP2 group
19  2019 [The role of abnormal mitochondrial fusion and fission in PBDE-47-induced change in mitochondrial mass in PC12 cells]. Mfn1, NAO
20  2018 Activation of protein kinase C-alpha/heme oxygenase-1 signaling pathway improves mitochondrial dynamics in lipopolysaccharide-activated NR8383 cells. Drp1, HO-1, LPS, Mfn1, Mfn2, OPA1, PKCalpha, RCR, ROS
21  2018 Benfotiamine, a Lipid-Soluble Analog of Vitamin B1, Improves the Mitochondrial Biogenesis and Function in Blunt Snout Bream (Megalobrama amblycephala) Fed High-Carbohydrate Diets by Promoting the AMPK/PGC-1beta/NRF-1 Axis. AMP, AMPK, ATP, ATP-6, COX-2, cytb, Drp1, FCR, HC, MFF, Mfn1, NRF1, OPA1, PGC-1beta, RFI, SGR, WGR
22  2018 Cocoa beans improve mitochondrial biogenesis via PPARgamma/PGC1alpha dependent signalling pathway in MPP+ intoxicated human neuroblastoma cells (SH-SY5Y). Mfn2, PD
23  2018 Dynamin-related protein 1-mediated mitochondrial fission contributes to IR-783-induced apoptosis in human breast cancer cells. ATP, Cyto C, Drp1, MFF, Mfn1, MMP, mPTP, OPA1
24  2018 Irisin alleviates liver ischemia-reperfusion injury by inhibiting excessive mitochondrial fission, promoting mitochondrial biogenesis and decreasing oxidative stress. drp-1, I/R, PPARgamma, UCP
25  2018 Protective role of STVNa in myocardial ischemia reperfusion injury by inhibiting mitochondrial fission. Drp1, IR
26  2018 [Effects of fluoride exposure on thyroid hormone level and intelligence in rats]. Mfn1
27  2017 Effect of Mahuang Gancao Ganjiang Decoction on Fusion and Fission of Mitochondria and Apoptosis of Lymphocytes in Mice under Cold Stress. Drp1, Mfn1, Mfn2, MGGD, Opa-1
28  2017 Mitochondrial dynamics in type 2 diabetes: Pathophysiological implications. Drp1, mdivi-1, MFF, Mfn1, Mfn2, PINK1, ROS
29  2017 Neuroprotective Effect and Mechanism of Thiazolidinedione on Dopaminergic Neurons In Vivo and In Vitro in Parkinson's Disease. Mfn2, NRF1, PGC-1alpha
30  2017 Pro-Inflammatory CXCR3 Impairs Mitochondrial Function in Experimental Non-Alcoholic Steatohepatitis. Drp1, Mfn1, NASH, ROS, TEM, WT
31  2017 Removal of a consensus proline is not sufficient to allow tetratricopeptide repeat oligomerization. TPR
32  2016 Mitochondrial Dynamics and Mitochondrial Dysfunction in Diabetes. Drp1, ERRs, MFF, Mfn1, Mfn2, NRFs, OPA1, PGC-1alpha, PINK1, PPARs, PTEN, ROS
33  2016 The Effect of Propofol on Mitochondrial Fission during Oxygen-Glucose Deprivation and Reperfusion Injury in Rat Hippocampal Neurons. AIF, CaN, Cyt C, Drp1, I/R, OGD/R
34  2016 The role of Drp1 adaptor proteins MiD49 and MiD51in mitochondrial fission: implications for human disease. Drp1, MFF, OMM, OPA1, PAH
35  2015 Acetyl-L-carnitineameliorates mitochondrial damage and apoptosis following spinal cord injury in rats. ALC, Bax, Drp1, Mfn1, SCI
36  2015 Allicin Protects PC12 Cells Against 6-OHDA-Induced Oxidative Stress and Mitochondrial Dysfunction via Regulating Mitochondrial Dynamics. Drp1, LDH, MMP, OPA1, PD, ROS
37  2015 Neural stem cell transplantation enhances mitochondrial biogenesis in a transgenic mouse model of Alzheimer's disease-like pathology. AD, APP, Drp1, Mfn1, NSC, OPA1
38  2015 Retinol binding protein 4 induces mitochondrial dysfunction and vascular oxidative damage. Drp1, HAECs, Mfn, PI3K, RBP4, ROS
39  2014 The decreased expression of mitofusin-1 and increased fission-1 together with alterations in mitochondrial morphology in the kidney of rats with chronic fluorosis may involve elevated oxidative stress. MDA, Mfn1, SD, T-AOC
40  2014 The relationship between mitochondrial fusion/fission and apoptosis in the process of adipose-derived stromal cells differentiation into astrocytes. ADSCs, Caspase-3, GFAP, Mfn2, TEM
41  2013 Adaptability to hypobaric hypoxia is facilitated through mitochondrial bioenergetics: an in vivo study. DEX, Drp1, ERRalpha, HAPE, HH, Mfn2, mtDNA, NN, PGC-1alpha
42  2013 Hyperglycemia alters mitochondrial fission and fusion proteins in mice subjected to cerebral ischemia and reperfusion. Drp1, LC3, MCAO, Mfn2, NRF1, OPA1, PGC-1alpha
43  2012 Dynamic changes of mitochondrial fission proteins after transient cerebral ischemia in mice. p-DRP1, tMCAO, TUNEL
44  2012 The influence of chronic fluorosis on mitochondrial dynamics morphology and distribution in cortical neurons of the rat brain. Drp1, Mfn1
45  2012 [Alteration of mitochondrial distribution and gene expression of fission 1 protein in cortical neurons of rats with chronic fluorosis]. ---
46  2010 Dynamin-related protein 1 and mitochondrial fragmentation in neurodegenerative diseases. Drp1
47  2009 Evidence for conformational heterogeneity of fission protein Fis1 from Saccharomyces cerevisiae. ---
48  2009 Response of mitochondrial fusion and fission protein gene expression to exercise in rat skeletal muscle. Mfn, ROS