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Abbreviation : GEC
Long Form : glomerular epithelial cells
No. Year Title Co-occurring Abbreviation
2022 Exosomal circTAOK1 contributes to diabetic kidney disease progression through regulating SMAD3 expression by sponging miR-520h. CCK-8, circRNA, DN, EdU, EMT, GMC, GMCs, HG, miR-520h, PCNA, RIP, RT-qPCR, SMAD3
2022 The unfolded protein response transducer IRE1α promotes reticulophagy in podocytes. ER, IRE1alpha, KO, RTN3L
2021 Extracellular Vesicles Derived from Endothelial Progenitor Cells Protect Human Glomerular Endothelial Cells and Podocytes from Complement- and Cytokine-Mediated Injury. CK, EPC, EVs, GFB, IL-6, TNF-alpha
2021 Glomerular Endothelial Cell-Derived microRNA-192 Regulates Nephronectin Expression in Idiopathic Membranous Glomerulonephritis. GBM, GFB, IMGN, miRs, NPNT
2020 Glomerular endothelial cell heterogeneity in Alport syndrome. AS, WT
2020 Glomerular endothelial cells and podocytes can express CD80 in patients with minimal change disease during relapse. INS, MCD
2020 Hirudin reduces nephropathy microangiopathy in STZ-induced diabetes rats by inhibiting endothelial cell migration and angiogenesis. ---
2020 Role of IRE1alpha in podocyte proteostasis and mitochondrial health. ER, IRE1alpha, UPR
2020 Single cell transcriptomics identifies focal segmental glomerulosclerosis remission endothelial biomarker. A2M, ERCB, FSGS
10  2020 The diabetic microenvironment causes mitochondrial oxidative stress in glomerular endothelial cells and pathological crosstalk with podocytes. DKD, HG, MitoSOX
11  2019 CD8+CD103+ iTregs inhibit the progression of lupus nephritis by attenuating glomerular endothelial cell injury. qRT-PCR
12  2019 Increased urinary excretion of hedgehog interacting protein (uHhip) in early diabetic kidney disease. Cr, DKD, HHIP, UACR, uHhip, uHhip
13  2019 Metabolomic analysis of Shiga toxin 2a-induced injury in conditionally immortalized glomerular endothelial cells. ciGEnC, Stx2a
14  2018 Gene expression profiles of glomerular endothelial cells support their role in the glomerulopathy ofdiabetic mice. DN, STZ-WT
15  2018 Kruppel-like factor 4 is a negative regulator of STAT3-induced glomerular epithelial cell proliferation. FSGS, KLF4, RPGN
16  2018 Preeclampsia serum induces human glomerular vascular endothelial cell hyperpermeability via the HMGB1-Caveolin-1 pathway. CAV-1, GA, HMWP, MBCD, NPS, PE, PES, rHMGB1
17  2017 Exosomes from high glucose-treated glomerular endothelial cells trigger the epithelial-mesenchymal transition and dysfunction of podocytes. DN, EMT, EndoMT, HG, NG
18  2017 LY333531, a PKCbeta inhibitor, attenuates glomerular endothelial cell apoptosis in the early stage of mouse diabetic nephropathy via down-regulating swiprosin-1. DN, HRGECs
19  2016 Glomerular Epithelial Cells-Targeted Heme Oxygenase-1 Over Expression in the Rat: Attenuation of Proteinuria in Secondary But Not Primary Injury. Ab, GBM, GN, HO-1, PAN, WT
20  2016 Role of the deubiquitinating enzyme ubiquitin-specific protease-14 in proteostasis in renal cells. ER, USP14
21  2015 Expression and regulation of scavenger receptor class B type 1 in the rat ovary and uterus during the estrous cycle. CL, CM, GC, IC, IHC, LEC, SC, SR-B1, T-I
22  2015 Presence of an HO-1 expression threshold in renal glomeruli. HO
23  2014 Expression of Ser729 phosphorylated PKCepsilon in experimental crescentic glomerulonephritis: an immunohistochemical study. CGN
24  2014 Glomerular endothelial cell injury and cross talk in diabetic kidney disease. DKD, ESRD, VEGF
25  2013 Role of guanine nucleotide exchange factor-H1 in complement-mediated RhoA activation in glomerular epithelial cells. PHN
26  2012 Complement modulates the function of the ubiquitin-proteasome system and endoplasmic reticulum-associated degradation in glomerular epithelial cells. ER, ERAD, UPS
27  2012 Complement-mediated activation of calcium-independent phospholipase A2gamma: role of protein kinases and phosphorylation. EGF, ERK, JNK, MAPKs, MEK1, MNK1
28  2012 Mizoribine suppresses proliferation of rat glomerular epithelial cells in culture and inhibits increase of monocyte chemoattractant protein-1 and macrophage inflammatory protein-2 stimulated by thrombin. ELISA, MCP-1, MIP-2, MZR, RT-PCR
29  2012 PR3 and elastase alter PAR1 signaling and trigger vWF release via a calcium-independent mechanism from glomerular endothelial cells. PARs, PR3, vWF
30  2011 Stem cells from foreign body granulation tissue accelerate recovery from acute kidney injury. AKI, GTSC
31  2010 Cytochrome P450 2B1 mediates complement-dependent sublytic injury in a model of membranous nephropathy. CYP2B1
32  2010 Endoplasmic reticulum stress in glomerular epithelial cell injury. ECM, eIF2alpha, ER, FSGS
33  2009 GEC-targeted HO-1 expression reduces proteinuria in glomerular immune injury. Ab, GBM, HO
34  2009 Glomerular epithelial cell injury associated with mutant alpha-actinin-4. CHOP, ER, FSGS
35  2009 Human glomerular endothelium: interplay among glucose, free fatty acids, angiotensin II, and oxidative stress. COX-2, DN, eNOS, FFA, PGs, ROS
36  2009 Resveratrol ameliorates high glucose-induced protein synthesis in glomerular epithelial cells. AMPK
37  2009 The cytoprotective role of Ras in complement-mediated glomerular epithelial cell injury. ---
38  2008 Abnormal glomerular permeability characteristics in diabetic nephropathy: implications for the therapeutic use of low-molecular weight heparin. GBM
39  2008 Glomerular angiotensinogen protein is enhanced in pediatric IgA nephropathy. AGT, Ang II, IgAN, MGA, mRNA, RAS, RT-PCR, TGF-beta
40  2008 Role of apoptosis signal-regulating kinase 1 in complement-mediated glomerular epithelial cell injury. ASK1, JNK, PHN, ROS
41  2008 Role of calcium-independent phospholipase A2 in complement-mediated glomerular epithelial cell injury. AA, BEL
42  2008 The expression and ovarian steroid regulation of endometrial micro-RNAs. ECE, miRNAs, NE
43  2008 The role of type V collagen fibril as an ECM that induces the motility of glomerular endothelial cells. ---
44  2007 Role of Rho-GTPases in complement-mediated glomerular epithelial cell injury. CA, DN, PHN
45  2007 The expression profile of micro-RNA in endometrium and endometriosis and the influence of ovarian steroids on their expression. ESC, miRNAs
46  2006 Prostaglandin E2 promotes cell survival of glomerular epithelial cells via the EP4 receptor. COX, PAN, PG
47  2005 Actin cytoskeleton regulates extracellular matrix-dependent survival signals in glomerular epithelial cells. ERK, FAK
48  2005 Activation of the extracellular signal-regulated kinase by complement C5b-9. ERK, MEK, PHN
49  2005 Analysis of the guinea-pig estrogen-regulated gec1/GABARAPL1 gene promoter and identification of a functional ERE in the first exon. Inr
50  2005 Experimental membranous nephropathy redux. HN, MN
51  2005 Role of the endoplasmic reticulum unfolded protein response in glomerular epithelial cell injury. eIF2alpha, ER
52  2004 A hemodynamically mediated mechanism of renal disease progression in severe glomerulonephritides or nephrosis. ---
53  2004 Aggregated IgG bind to glomerular epithelial cells to stimulate urokinase release through an endocytosis-independent process. AgIgG, uPA
54  2004 Onset of direct 17-beta estradiol effects on proliferation and c-fos expression during oncogenesis of endometrial glandular epithelial cells. IGEC
55  2004 SRC-family kinase Fyn phosphorylates the cytoplasmic domain of nephrin and modulates its interaction with podocin. ---
56  2003 Activation of the TGF-beta/Smad signaling pathway in focal segmental glomerulosclerosis. ECM, FSGS, GLEPP1, TGF-beta, TGF-betaIIR, TSP-1, WT1
57  2003 Extracellular matrix regulates glomerular epithelial cell survival and proliferation. FAK, PAN
58  2003 Improved TRAP-silver staining versus conventional radioactive TRAP assays: quantification of telomerase activity during immortalization and in pathological human endometrium. TRAP
59  2003 p38 mitogen-activated protein kinase protects glomerular epithelial cells from complement-mediated cell injury. MAPKAPK2, PHN, TAK1
60  2003 Rat glomerular epithelial cells produce and bear factor H on their surface that is up-regulated under complement attack. PCR, PHN, RT
61  2003 Role of cytochrome P450 2B1 in puromycin aminonucleoside-induced cytotoxicity to glomerular epithelial cells. NS, PAN
62  2003 Role of oxidative stress and heme oxygenase activity in morphine-induced glomerular epithelial cell growth. HO
63  2003 The actin cytoskeleton facilitates complement-mediated activation of cytosolic phospholipase A2. AA, DAG
64  2003 The localization of adrenomedullin in rat kidney tissue and its inhibitory effect on the growth of cultured rat mesangial cells. AM, MsC
65  2003 Third-generation beta-blockers stimulate nitric oxide release from endothelial cells through ATP efflux: a novel mechanism for antihypertensive action. ---
66  2003 [Effects of lysophosphatidylcholine on expression of monocyte chemoattractant protein-1 in glomerular endothelial cells]. lysoPC, MCP-1, ox-LDL, PKC, TK
67  2002 Complement activates the c-Jun N-terminal kinase/stress-activated protein kinase in glomerular epithelial cells. AA, JNK
68  2002 Complement C5b-9 membrane attack complex increases expression of endoplasmic reticulum stress proteins in glomerular epithelial cells. ER, PHN
69  2002 Detection of mRNA for alpha-3 chain of type IV collagen in the glomerular epithelium, and the effect of perfused elastase on its expression. GBM
70  2002 Effects of peripheral blood mononuclear cells from idiopathic nephrotic children on cultured rat glomerular epithelial and mesangial cells. ECM, PBMC, PBMC-CM
71  2002 Isolation and characterization of a novel rat factor H-related protein that is up-regulated in glomeruli under complement attack. FHR, SCR
72  2002 Shiga toxin-2 triggers endothelial leukocyte adhesion and transmigration via NF-kappaB dependent up-regulation of IL-8 and MCP-1. HUS, HUVEC, IL-8, MCP-1, NF-kappaB, Stx
73  2002 VEGF-induced mobilization of caveolae and increase in permeability of endothelial cells. VEGF
74  2001 Altering glomerular epithelial function in vitro using transient and stable transfection. ---
75  2001 Combinatorial model of chemokine involvement in glomerular monocyte recruitment: role of CXC chemokine receptor 2 in infiltration during nephrotoxic nephritis. GRO, MCP
76  2001 Complement C5b-9 induces cyclooxygenase-2 gene transcription in glomerular epithelial cells. COX, MEKK, PKC, PMA
77  2001 Cultured rat glomerular epithelial cells show gene expression and production of transforming growth factor-beta: expression is enhanced by thrombin. RT-PCR, TGF-beta
78  2001 Cytochrome P-450 as a source of catalytic iron in minimal change nephrotic syndrome in rats. CYP, MCNS, PAN
79  2001 Expression of adhesion molecules by cultured human glomerular endothelial cells in response to cytokines: comparison to human umbilical vein and dermal microvascular endothelial cells. IFN-gamma, MVE, TNF-alpha
80  2001 In vitro decrease of glomerular heparan sulfate by lymphocytes from idiopathic nephrotic syndrome patients. GAGs, HS, INS, PBL, PBMCs
81  2001 Interleukin-1beta is an autocrine growth factor of rat glomerular epithelial cells in culture. ELISA, IFN-gamma, IL-1beta, RT-PCR
82  2001 Morphological differences between glomerular epithelial cells (GEC) excreted during chemotherapy with antineoplastic drugs and GEC excreted in renal diseases. ---
83  2001 Puromycin aminonucleoside induces glomerular epithelial cell apoptosis. DMTU, PAN, SOD
84  2001 Shiga toxin-1 regulation of cytokine production by human glomerular epithelial cells. CHX, IL-1, IL-6, LPS, Stx, TNF
85  2000 Characterization and localization of the neonatal Fc receptor in adult human kidney. ---
86  2000 Complement C5b-9-mediated arachidonic acid metabolism in glomerular epithelial cells : role of cyclooxygenase-1 and -2. COX, PG, PHN
87  2000 Complement-induced phospholipase A2 activation in experimental membranous nephropathy. AA, cPLA2, PHN, PLA2, sPLA2
88  2000 Identification, cellular distribution and potential function of the metalloprotease-disintegrin MDC9 in the kidney. ---
89  1999 Complement C5b-9 induces receptor tyrosine kinase transactivation in glomerular epithelial cells. EGFR, ERK2, PHN
90  1999 Complement-mediated injury reversibly disrupts glomerular epithelial cell actin microfilaments and focal adhesions. ---
91  1999 Detection of WT1 mRNA in urine from patients with kidney diseases. CGN, DM, GBM
92  1999 HIV-1 gp120 envelope protein modulates proliferation of human glomerular epithelial cells. HIV, PCNA
93  1999 Identification of soluble interleukin-4 receptor in rat glomerular epithelial cells(1). IL, mIL-4R, sIL-4R
94  1999 Role of extracellular matrix and Ras in regulation of glomerular epithelial cell proliferation. ECM, EGF, HGF, MAP
95  1999 TNF-alpha induces actin cytoskeleton reorganization in glomerular epithelial cells involving tyrosine phosphorylation of paxillin and focal adhesion kinase. GBM, TNF-alpha
96  1998 Complement activates phospholipases and protein kinases in glomerular epithelial cells. AA, cPLA2, cPLA2-SA505, MAPK, PKC, WT
97  1998 Differential regulation of matrix metalloproteinases and their inhibitors in human glomerular epithelial cells in vitro. IL-1beta, MMP, TGF-beta1, TIMP-I
98  1998 Effect of glycated proteins on the matrix of glomerular epithelial cells. FBS
99  1998 Enhanced expression of the cytoskeletal-associated protein, paxillin, in experimental nephrotic syndrome. FAK
100  1998 ERE environment- and cell type-specific transcriptional effects of estrogen in normal endometrial cells. ERE