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Abbreviation : HDAC1
Long Form : histone deacetylase 1
No. Year Title Co-occurring Abbreviation
2023 Histone Deacetylase 1 Expression and Regulatory Network in Lung Adenocarcinoma Based on Data Mining and Implications for Targeted Treatment. LUAD
2023 Histone deacetylation-regulated cell surface Siglec-7 expression promoted megakaryocytic maturation and enhanced platelet-like particle release. MK, PLPs, Siglec-7
2023 Proteomics-based trapping with single or multiple inactive mutants reproducibly profiles histone deacetylase 1 substrates. CARNMT1, HDAC
2022 Altered Cellular Immunity and Differentially Expressed Immune-Related Genes in Patients With Systemic Sclerosis-Associated Pulmonary Arterial Hypertension. CTD, DEGs, EGFR, GEO, GO, GSEA, IL-7R, IRGs, KEGG, PAH, PBMCs, PPI, SSc
2022 Anti-Colon Cancer Activity of Novel Peptides Isolated from In Vitro Digestion of Quinoa Protein in Caco-2 Cells. RT-qPCR
2022 Butyrate Attenuates Hepatic Steatosis Induced by a High-Fat and Fiber-Deficient Diet via the Hepatic GPR41/43-CaMKII/HDAC1-CREB Pathway. CaMKII, GPR41, WT
2022 Cannabidiol-rich non-psychotropic Cannabis sativa L. oils attenuate peripheral neuropathy symptoms by regulation of CB2-mediated microglial neuroinflammation. Delta9 -THC, IL-10, MAPKs, NP
2022 Chromatin Remodeling Induced by ARID1A Loss in Lung Cancer Promotes Glycolysis and Confers JQ1 Vulnerability. BET, HIF1alpha, PKM, SWI/SNF
2022 CREB inactivation by HDAC1/PP1gamma contributes to dopaminergic neurodegeneration in Parkinson's disease. PD, PP1gamma
10  2022 CREPT Disarms the Inhibitory Activity of HDAC1 on Oncogene Expression to Promote Tumorigenesis. ChIP
11  2022 Downregulation of Sp1 Inhibits the Expression of HDAC1/SOX10 to Alleviate Neuropathic Pain-like Behaviors after Spinal Nerve Ligation in Mice. NeuN, NP, PWL, PWT, SNL, SOX10, Sp1
12  2022 E3 ubiquitin ligase NEURL3 promotes innate antiviral response through catalyzing K63-linked ubiquitination of IRF7. IFN, IRF7, ISGs, NEURL3
13  2022 Enhancer recruitment of a RUNX1, HDAC1 and TLE3 co-repressor complex by mis-expressed FOXC1 blocks differentiation in acute myeloid leukemia. FOXC1, TLE3
14  2022 Exosomal lncRNA HOTAIR Promotes the Progression and Angiogenesis of Endometriosis via the miR-761/HDAC1 Axis and Activation of STAT3-Mediated Inflammation. ESCs, HOTAIR, HUVECs, lncRNA, miR, siRNA, STAT3
15  2022 Expression of Protein Acetylation Regulators During Peripheral Nerve Development, Injury, and Regeneration. ---
16  2022 Ferulic Acid and P-Coumaric Acid Synergistically Attenuate Non-Alcoholic Fatty Liver Disease through HDAC1/PPARG-Mediated Free Fatty Acid Uptake. FA, FABP, HFD, NAFLD, OA, p-CA, PA, PPARG
17  2022 HAUSP Is a Key Epigenetic Regulator of the Chromatin Effector Proteins. DNMT1, PHD
18  2022 HDAC1 expression is positively correlated with NADPH oxidase 4-mediated oxidative stress in a mouse model of traumatic brain injury. LFPI, MDA, mNSS, NOX4, SOD, TBI
19  2022 HDAC1 overexpression promoted by METTL3-IGF2BP2 inhibits FGF21 expression in metabolic syndrome-related liver injury. FGF21, m6A, MetS, METTL3
20  2022 HDAC1 PREDICTOR: a simple and transparent application for virtual screening of histone deacetylase 1 inhibitors. QSAR
21  2022 HDAC1 regulates inflammation and osteogenic differentiation of ankylosing spondylitis fibroblasts through the Wnt-Smad signaling pathway. AAV, ALP, AS
22  2022 Hepatic RACK1 deficiency protects against fulminant hepatitis through myeloid-derived suppressor cells. FH, IKK, MDSCs, RACK1, S100A9
23  2022 Histone deacetylase 1 in patients with alopecia areata and acne vulgaris: An epigenetic alteration. AA
24  2022 Histone deacetylase 1, Sirtuin 1, and Sirtuin 3 single-nucleotide polymorphisms and the risk of endometriosis in South Indian women. SIRT1, SIRT3, SNPs
25  2022 Hsa-microRNA-370-3p targeting Snail and Twist1 suppresses IL-8/STAT3-driven hepatocellular carcinoma metastasis. HCC, IL-8, miR, STAT3
26  2022 KTN1-AS1, a SOX2-mediated lncRNA, activates epithelial-mesenchymal transition process in esophageal squamous cell carcinoma. EMT, ESCC, KTN1-AS1, lncRNA, RBBP4
27  2022 LKB1 on POMC neurons affect the formation of diet-induced obesity by regulating the expression of HDAC1. LKB1, PPARgamma
28  2022 LRF Promotes Indirectly Advantageous Chromatin Conformation via BGLT3-lncRNA Expression and Switch from Fetal to Adult Hemoglobin. DNMT3, HbF
29  2022 MARCKSL1-2 reverses docetaxel-resistance of lung adenocarcinoma cells by recruiting SUZ12 to suppress HDAC1 and elevate miR-200b. DTX, LAD, lncRNAs, MARCKSL1-2, miR-200b, SUZ12
30  2022 Melatonin decreases androgen-sensitive prostate cancer growth by suppressing SENP1 expression. AR, IHC, MTT, PLA, qRT-PCR, SUMO
31  2022 Molecular networks of hepatoblastoma predisposition and oncogenesis in Beckwith-Wiedemann syndrome. BWS, FOXO3, HB, MAPK, PI3K
32  2022 Novel antimyeloma therapeutic option with inhibition of the HDAC1-IRF4 axis and PIM kinase. MM
33  2022 Perivascular Fibrosis Is Mediated by a KLF10-IL-9 Signaling Axis in CD4+ T Cells. KLF10, TF
34  2022 PFKM inhibits doxorubicin-induced cardiotoxicity by enhancing oxidative phosphorylation and glycolysis. DOX, HF, OXPHOS, RT-PCR
35  2022 Predicting Glioma Cell Differentiation-inducing Drugs Using a Drug Repositioning Strategy. DEGs
36  2022 Quantitative Phosphoproteomics of the Angiotensin AT2-Receptor Signaling Network Identifies HDAC1 (Histone-Deacetylase-1) and p53 as Mediators of Antiproliferation and Apoptosis. ---
37  2022 Roseburia hominis Alleviates Neuroinflammation via Short-Chain Fatty Acids through Histone Deacetylase Inhibition. GF, R. hominis
38  2022 SNHG25 facilitates SNORA50C accumulation to stabilize HDAC1 in neuroblastoma cells. NB, SNHG25, SNORA50C, snoRNAs, snoRNP
39  2022 Suberoylanilide hydroxamic acid suppresses axonal damage and neurological dysfunction after subarachnoid hemorrhage via the HDAC1/HSP70/TDP-43 axis. HSP70, SAH, SAHA
40  2022 Suppression of Allergic Asthma by Loss of Function of Miz1-mediated Th1 Skewing. ---
41  2022 Temporal, spatial and molecular pattern of dopaminergic neurodegeneration in the AAV-A53T alpha-synuclein rat model of Parkinson's disease. PD, SN
42  2022 The CtIP-CtBP1/2-HDAC1-AP1 transcriptional complex is required for the transrepression of DNA damage modulators in the pathogenesis of osteosarcoma. AP-1, BRCA1, CDKN1A, ChIP, CtBP, MLH1, MSH3
43  2022 The Effect of Ginger and Its Sub-Components on Pain. DRG, NMDA, SP, TRPV1
44  2022 The emerging role of histone deacetylase 1 in allergic diseases. IL-10, Th2, TREK-1
45  2022 The Potential Mechanism of HDAC1-Catalyzed Histone Crotonylation of Caspase-1 in Nonsmall Cell Lung Cancer. NSCLC, PEM, RNA Pol II
46  2022 The Potential Role of Nigella sativa Seed Oil as Epigenetic Therapy of Cancer. BSO, DNMT1, PHD, TQ
47  2022 TOPK Affects Autophagy of Skin Squamous Cell Carcinoma by Regulating NF-KB Pathway through HDAC1. cSCC, LC3, NF-kappaB p65, p-IkappaBalpha, TOPK
48  2022 Vaccarin alleviates endothelial inflammatory injury in diabetes by mediating miR-570-3p/HDAC1 pathway. HUVECs, STZ
49  2022 Yi-Xin-Shu capsule ameliorates cardiac hypertrophy by regulating RB/HDAC1/GATA4 signaling pathway based on proteomic and mass spectrometry image analysis. CH, CHF, DEP, GATA4, HE, Rb, RTQ, YXS
50  2022 Zonula occludens-1 expression is reduced in nasal epithelial cells of allergic rhinitis patients. AR, HDMs, ZO-1
51  2021 8a, a New Acridine Antiproliferative and Pro-Apoptotic Agent Targeting HDAC1/DNMT1. DNMT1, HDAC
52  2021 Aging-related hyperphosphatemia impairs myogenic differentiation and enhances fibrosis in skeletal muscle. BGP, MEF2C, Myf5, MyoG, Pax7
53  2021 Apoptotic effects of valproic acid on miR-34a, miR-520h and HDAC1 gene in breast cancer. VPA
54  2021 Application of machine learning to large in-vitro databases to identify cancer cell characteristics: telomerase reverse transcriptase (TERT) expression. TERT
55  2021 BAP1 forms a trimer with HMGB1 and HDAC1 that modulates gene environment interaction with asbestos. HMGB1
56  2021 Bipartite regulation of cellular communication network factor 2 and fibroblast growth factor 1 genes by fibroblast growth factor 1 through histone deacetylase 1 and fork head box protein A1. CCN2, FGF1, FOXA1
57  2021 Cadmium disturbs epigenetic modification and induces DNA damage in mouse preimplantation embryos. ROS
58  2021 CHD4 as an important mediator in regulating the malignant behaviors of colorectal cancer. CHD4, CRC
59  2021 Chronic Exposure to Alcohol Inhibits New Myelin Generation in Adult Mouse Brain. OPCs
60  2021 CircRNA RSF1 regulated ox-LDL induced vascular endothelial cells proliferation, apoptosis and inflammation through modulating miR-135b-5p/HDAC1 axis in atherosclerosis. AS, Bax, Bcl-2, HUVECs, ICAM-1, VCAM-1
61  2021 Combination Treatment of CI-994 With Etoposide Potentiates Anticancer Effects Through a Topoisomerase II-Dependent Mechanism in Atypical Teratoid/Rhabdoid Tumor (AT/RT). AT/RT, CI, RT-qPCR, topo
62  2021 Correction: Death domain-associated protein 6 (Daxx) selectively represses IL-6 transcription through histone deacetylase 1 (HDAC1)-mediated histone deacetylation in macrophages. ---
63  2021 Differential MUC22 expression by epigenetic alterations in human lung squamous cell carcinoma and adenocarcinoma. LUAD, MUC22, MUC22Low, MUCs, NSCLC, TSA
64  2021 Discovery of quinazolinyl-containing benzamides derivatives as novel HDAC1 inhibitors with in vitro and in vivo antitumor activities. ---
65  2021 Ellagic Acid Alleviates Rheumatoid Arthritis in Rats through Inhibiting MTA1/HDAC1-Mediated Nur77 Deacetylation. CIA, EA, FLS, MTA1, RA
66  2021 Epigenetic regulation of p62/SQSTM1 overcomes the radioresistance of head and neck cancer cells via autophagy-dependent senescence induction. DNMT1
67  2021 Epigenetic targeting of SLC30A3 by HDAC1 is related to the malignant phenotype of glioblastoma. ChIP-seq, GBM, SE, SLC30A3
68  2021 Epigenetic therapy combination of UNC0638 and CI-994 suppresses breast cancer via epigenetic remodeling of BIRC5 and GADD45A. BC, ChIP-qPCR, EHMT2, GSEA
69  2021 Exendin-4 promotes bone formation in diabetic states via HDAC1-Wnt/beta-catenin axis. BMSCs, T2DM
70  2021 Extracellular Vesicle-Derived microRNA-410 From Mesenchymal Stem Cells Protects Against Neonatal Hypoxia-Ischemia Brain Damage Through an HDAC1-Dependent EGR2/Bcl2 Axis. Bcl2, EGR2, EVs, HIBD, HUC, miR, mNSS, MSCs, OGD
71  2021 HDAC1 deregulation promotes neuronal loss and deficit of motor function in stroke pathogenesis. ---
72  2021 HDAC1 regulates the chemosensitivity of laryngeal carcinoma cells via modulation of interleukin-8 expression. 5-FU, IL-8, LSCC
73  2021 HDAC1-mediated deacetylation of HIF1alpha prevents atherosclerosis progression by promoting miR-224-3p-mediated inhibition of FOSL2. EC, FOSL2, HAECs, HIF1alpha, miR, ox-LDL, ROS
74  2021 HDAC6 Substrate Discovery Using Proteomics-Based Substrate Trapping: HDAC6 Deacetylates PRMT5 to Influence Methyltransferase Activity. HDAC6, PRMT5
75  2021 Histone deacetylase 1 controls cardiomyocyte proliferation during embryonic heart development and cardiac regeneration in zebrafish. bal, ENU
76  2021 Histone deacetylase 1 controls CD4+ T cell trafficking in autoinflammatory diseases. EAE
77  2021 Histone deacetylase 1 facilitates aerobic glycolysis and growth of endometrial cancer. ---
78  2021 HOXA10 promotion of HDAC1 underpins the development of lung adenocarcinoma through the DNMT1-KLF4 axis. DNMT1, HOXA10, KLF4, LAD
79  2021 Inhibition of Epigenetic Modifiers LSD1 and HDAC1 Blocks Rod Photoreceptor Death in Mouse Models of Retinitis Pigmentosa. LSD1, RP
80  2021 Inhibition of HDAC1 alleviates monocrotaline-induced pulmonary arterial remodeling through up-regulation of miR-34a. ECM, MCT, MMP-9, PAH, RVHI, RVSP, TIMP-1
81  2021 Inhibition of hsa_circ_0003489 shifts balance from autophagy to apoptosis and sensitizes multiple myeloma cells to bortezomib via miR-874-3p/HDAC1 axis. BTZ, circRNAs, MM
82  2021 Interfering microRNA-410 attenuates atherosclerosis via the HDAC1/KLF5/IKBalpha/NF-kappaB axis. CCK-8, coIP, miR, NF-kappaB, ox-LDL, RIP
83  2021 Involvement of 5-HT1A receptor-mediated histone acetylation in the regulation of depression. HDAC, HDAC2, HDAC4, HDAC5
84  2021 JAK-STAT Pathway Inhibition Partially Restores Intestinal Homeostasis in Hdac1- and Hdac2-Intestinal Epithelial Cell-Deficient Mice. IEC, MHC
85  2021 KCTD19 and its associated protein ZFP541 are independently essential for meiosis in male mice. ZFP541
86  2021 Lactational polychlorinated biphenyls exposure induces epigenetic alterations in the Leydig cells of progeny rats. PND
87  2021 Long noncoding RNA NEAT1 inhibits the acetylation of PTEN through the miR-524-5p /HDAC1 axis to promote the proliferation and invasion of laryngeal cancer cells. ---
88  2021 Marek's disease virus Meq oncoprotein interacts with chicken HDAC 1 and 2 and mediates their degradation via proteasome dependent pathway. bZIP, chHDAC1, MDV
89  2021 MCM5 Aggravates the HDAC1-Mediated Malignant Progression of Lung Cancer. EMT, MCM5
90  2021 Mesenchymal Stem Cell-Derived Exosomes Carry MicroRNA-125a to Protect Against Diabetic Nephropathy by Targeting Histone Deacetylase 1 and Downregulating Endothelin-1. AD-MSCs, Col I, DN, ET-1, FN, GMC, HG, IL-6, miRNA, MSC, UACR
91  2021 MicroRNA-146a-3p/HDAC1/KLF5/IKBalpha signal axis modulates plaque formation of atherosclerosis mice. AS, IkBalpha, KLF5, miR-146a-3p
92  2021 MicroRNA-449 targets histone deacetylase 1 to regulate the proliferation, invasion, and apoptosis of synovial fibroblasts in rheumatoid arthritis. miR, OA, OASFs, RA, RASFs
93  2021 Multi-Systemic Alterations by Chronic Exposure to a Low Dose of Bisphenol A in Drinking Water: Effects on Inflammation and NAD+-Dependent Deacetylase Sirtuin1 in Lactating and Weaned Rats. BPA, SIRT1
94  2021 Oroxylin A inhibits the migration of hepatocellular carcinoma cells by inducing NAG-1 expression. EMT, HCC, NAG-1, TGF-beta1
95  2021 Physalin B attenuates liver fibrosis via suppressing LAP2alpha-HDAC1-mediated deacetylation of the transcription factor GLI1 and hepatic stellate cell activation. GLI1, LAP2alpha, pHSCs, qRT-PCR
96  2021 Positive Reciprocal Feedback of lncRNA ZEB1-AS1 and HIF-1alpha Contributes to Hypoxia-Promoted Tumorigenesis and Metastasis of Pancreatic Cancer. HIF-1alpha, HRE, lncRNAs, PC, ZEB1
97  2021 POU2AF1 promotes MSCs adipogenesis by inhibiting HDAC1 expression. MSCs, POU2AF1
98  2021 Prenatal Iron Deficiency and Choline Supplementation Interact to Epigenetically Regulate Jarid1b and Bdnf in the Rat Hippocampus into Adulthood. BDNF, H3K9, ID, JARID1B, pCREB
99  2021 Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation. BioID, CoREST, ES, LSD1
100  2021 Recombinant human bone morphogenetic protein 2 and 7 inhibit the degeneration of intervertebral discs by blocking the Puma-dependent apoptotic signaling. IDD, NP, rhBMPs