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Abbreviation : HEK293
Long Form : human embryonic kidney 293
No. Year Title Co-occurring Abbreviation
2022 A quantitative high-throughput screen identifies compounds that lower expression of the SCA2-and ALS-associated gene ATXN2. 17-DMAG, ATXN2, HSP990, SCA2, STAU1
2022 Autophagy and mitochondrial dynamics contribute to the protective effect of diosgenin against 3-MCPD induced kidney injury. 3-MA, DIO, SD
2022 Development of a p72 trimer-based colloidal gold strip for detection of antibodies against African swine fever virus. ASFV, ELISA
2022 Effect of FKBP12-Derived Intracellular Peptides on Rapamycin-Induced FKBP-FRB Interaction and Autophagy. ATG5, FKBP, InPeps, MEF, mTORC1, PPI
2022 Effects of Lycium barbarum glycopeptide on renal and testicular injury induced by di(2-ethylhexyl) phthalate. DEHP, FOXO3a, HK-2, LbGp, p38 MAPK, SIRT1
2022 Exploring ITM2A as a new potential target for brain delivery. BBB, COMPACT, IMI, ITM2A, NHP
2022 Exploring the Therapeutic Potentials of Exopolysaccharides Derived From Lactic Acid Bacteria and Bifidobacteria: Antioxidant, Antitumor, and Periodontal Regeneration. Bb, EPS, hPDLFCs, HPLC, LAB, LDH, RT
2022 Immunosuppressive calcineurin inhibitor cyclosporine A induces proapoptotic endoplasmic reticulum stress in renal tubular cells. ATF6, CsA, ER, PT, TAC, UPR
2022 Investigations on Anticancer Potentials by DNA Binding and Cytotoxicity Studies for Newly Synthesized and Characterized Imidazolidine and Thiazolidine-Based Isatin Derivatives. ---
10  2022 JBP485, A Dual Inhibitor of Organic Anion Transporters (OATs) and Renal Dehydropeptidase-I (DHP-I), Protects Against Imipenem-Induced Nephrotoxicity. AUC, DDIs, DHP-I, HK-2, IMP, OATs
11  2022 Multipathway In Vitro Pharmacological Characterization of Specialized Proresolving G Protein-Coupled Receptors. ERK, fMLP, FPR2, GPCRs, RvE1, SPMs
12  2022 Multiple mechanisms underlie reduced potassium conductance in the p.T1019PfsX38 variant of hERG. ---
13  2022 Physiological Characterization of the Transporter-Mediated Uptake of the Reversible Male Contraceptive H2-Gamendazole Across the Blood-Testis Barrier. BTB, CHO, H2-GMZ, MDCK, SCs
14  2022 Reduction of photoswitched, nitrogen bridged N-acetyl diazocines limits inhibition of 17βHSD3 activity in transfected human embryonic kidney 293 cells. ---
15  2022 Synthesis and characterization of novel combretastatin analogues of 1,1-diaryl vinyl sulfones, with antiproliferative potential via in-silico and in-vitro studies. ---
16  2022 Ultrasound assisted chitosan coated iron oxide nanoparticles: Influence of ultrasonic irradiation on the crystallinity, stability, toxicity and magnetization of the functionalized nanoparticles. CS-SPIONs, EDX, FTIR, Ms, TEM, VSM, XRD, zeta
17  2021 Antibody Responses to SARS-CoV-2 After Infection or Vaccination in Children and Young Adults With Inflammatory Bowel Disease. ACE2, IBD, S-RBD
18  2021 Antineoplastic effectiveness of silver nanoparticles synthesized from Onopordum acanthium L. extract (AgNPs-OAL) toward MDA-MB231 breast cancer cells. AO/EB, FESEM, qRT-PCR, XRD
19  2021 Cell engineering for the production of hybrid-type N-glycans in HEK293 cells. ---
20  2021 Decrease in membrane fluidity and traction force induced by silica-coated magnetic nanoparticles. ATP
21  2021 Effect of Quercetin on Injury to Indomethacin-Treated Human Embryonic Kidney 293 Cells. NSAIDs
22  2021 Enhanced Stability of Long-Living Immobilized Recombinant beta-d-N-Acetyl-Hexosaminidase A on Polylactic Acid (PLA) Films for Potential Biomedical Applications. GALNAc, GlcNAc, HexA, PLA
23  2021 Enhancement of Transgene Expression by Mild Hypothermia Is Promoter Dependent in HEK293 Cells. TFs
24  2021 Evaluating an In-House Cell-Based Assay for Detecting Antibodies Against Muscle-Specific Tyrosine Kinase in Myasthenia Gravis. CBA, ELISA, MG, RIPA
25  2021 Expression profiles of interferon-related genes in cells infected with influenza A viruses or transiently transfected with plasmids encoding viral RNA polymerase. ---
26  2021 Fermented Gamma Aminobutyric Acid Improves Sleep Behaviors in Fruit Flies and Rodent Models. EEG, LB-GABA, NREM
27  2021 Functional Interaction Between Caveolin 1 and LRRC8-Mediated Volume-Regulated Anion Channel. Cav-1, Cav-3, LRRC8, VRAC
28  2021 Gallic Acid Alleviates Neuropathic Pain Behaviors in Rats by Inhibiting P2X7 Receptor-Mediated NF-kappaB/STAT3 Signaling Pathway. ATP, CCI
29  2021 Genetic defects are common in myopathies with tubular aggregates. TAs
30  2021 Glyco-engineered HEK 293-F cell lines for the production of therapeutic glycoproteins with human N-glycosylation and improved pharmacokinetics. ASGPR, MR
31  2021 Hairpin Transfer-Independent Parvovirus DNA Replication Produces Infectious Virus. HBoV1, nt, OriR, REH, WT
32  2021 Heterogeneous Subcellular Origin of Exosome-Mimetic Nanovesicles Engineered from Cells. CNVs, NTA
33  2021 Identification of loss-of-function RyR2 mutations associated with idiopathic ventricular fibrillation and sudden death. CPVT, EST, GOF, IVF, LOF, WT
34  2021 Impact of lipopolysaccharides on cultivation and recombinant protein expression in human embryonal kidney (HEK-293) cells. LPS, OM
35  2021 Improving the Translation of Organic Anion Transporting Polypeptide Substrates using HEK293 Cell Data in the Presence and Absence of Human Plasma via Physiologically Based Pharmacokinetic Modeling. OATP, PBPK, PK
36  2021 Installation of O-glycan sulfation capacities in human HEK293 cells for display of sulfated mucins. ---
37  2021 Integrin alphavbeta6-targeted MR molecular imaging of breast cancer in a xenograft mouse model. LSCM, MR, MRI, RGD
38  2021 Interaction Profiles of Central Nervous System Active Drugs at Human Organic Cation Transporters 1-3 and Human Plasma Membrane Monoamine Transporter. MDMA, R- and S-alpha-PVP, SERT, SLC22A1-3, SLC6
39  2021 Invitro renal toxicity evaluation of copper-based metal-organic framework HKUST-1 on human embryonic kidney cells. ---
40  2021 Isoforskolin, an adenylyl cyclase activator, attenuates cigarette smoke-induced COPD in rats. AC, BALF, COPD, CS, ISOF
41  2021 LKB1/AMPKalpha signaling pathway and mitochondrial fission/fusion dynamics regulate apoptosis induced by 3-chlorpropane-1,2-diol in HEK293cells. Mdivi-1
42  2021 Long Non-Coding PROX1-AS1 Expression Correlates with Renal Cell Carcinoma Metastasis and Aggressiveness. lncRNAs, PROX1-AS1, RCC
43  2021 Marine Bile Natural Products as Agonists of the TGR5 Receptor. DCA, TGR5, UDCA
44  2021 Membrane activity detection in cultured cells using phase-sensitive plasmonics. ---
45  2021 Microfluidic Formulation of DNA-Loaded Multicomponent Lipid Nanoparticles for Gene Delivery. HaCaT, LNPs, TE, TFR
46  2021 Mode-selective inhibitory effects of eugenol on the mouse TRPV1 channel. TRPV1
47  2021 Modulation of the rat angiotensin type 1a receptor by an upstream short open reading frame. Ang, AT1aR, GPCR, PKC, SII, sORF
48  2021 Optimized Recombinant Production of Secreted Proteins Using Human Embryonic Kidney (HEK293) Cells Grown in Suspension. ---
49  2021 Permeabilized Cryopreserved Human Hepatocytes as an Exogenous Metabolic System in a Novel Metabolism-Dependent Cytotoxicity Assay for the Evaluation of Metabolic Activation and Detoxification of Drugs Associated with Drug-Induced Liver Injuries: Results with Acetaminophen, Amiodarone, Cyclophosphamide, Ketoconazole, Nefazodone, and Troglitazone. GST, MDCA, PAPS, SULT, UDPGA, UGT
50  2021 Persian Gulf Snail Crude Venom (Conus textile): A Potential Source of Anti-Cancer Therapeutic Agents for Glioblastoma through Mitochondrial-Mediated Apoptosis. MMP, ROS, SDH
51  2021 Pharmacological Characterization of Veldoreotide as a Somatostatin Receptor 4 Agonist. CgA, SSTR
52  2021 Plant miR171 modulates mTOR pathway in HEK293 cells by targeting GNA12. GNA12
53  2021 Relationship between phosphorylamine-modification and molecular weight on transfection efficiency of chitosan. CHI, DChi, o-PEA, PDI
54  2021 Selection of the First 99mTc-Labelled Somatostatin Receptor Subtype 2 Antagonist for Clinical Translation-Preclinical Assessment of Two Optimized Candidates. p.i, sst2
55  2021 Selective Toxicity Effect of Fatty Acids Omega-3, 6 and 9 Combination on Glioblastoma Neurons through their Mitochondria. GBM, MMP, ROS, SDH
56  2021 Signal Transduction Mechanisms for Glucagon-Induced Somatolactin Secretion and Gene Expression in NileTilapia (Oreochromis niloticus) Pituitary Cells. AC, CaM, cAMP, CRE, GCG, NIL, PKA, PLC
57  2021 Streamlined Human Cell-Based Recombinase-Mediated Cassette Exchange Platform Enables Multigene Expression for the Production of Therapeutic Proteins. RMCE
58  2021 Structural and Functional Characterization of SARS-CoV-2 RBD Domains Produced in Mammalian Cells. ACE2, CHO, RBD, SARS-CoV-2
59  2021 The nephrotoxic potential of polystyrene microplastics at realistic environmental concentrations. MPs, PS-MPs
60  2021 Up-regulation of gasdermin C in mouse small intestine is associated with lytic cell death in enterocytes in worm-induced type 2 immunity. IL-13
61  2021 Would 20 nm Filtered Fetal Bovine Serum-Supplemented Media Support Growth of CHO and HEK-293 Cells? CHO, FBS
62  2020 3D bioprinting of cell-laden electroconductive MXene nanocomposite bioinks. ---
63  2020 3D printing of cell-laden electroconductive bioinks for tissue engineering applications. PEDOT
64  2020 Annexin A4 N-terminal peptide inhibits adenylyl cyclase 5 and limits beta-adrenoceptor-mediated prolongation of cardiac action potential. A4N1-22, AC, ANXA4, APD, beta-AR, cAMP, ICaL
65  2020 Anti-cancer effects of recombinant arazyme from Serratia Proteomaculans. r-arazyme, RT-PCR
66  2020 Assessment of Statin Interactions With the Human NTCP Transporter Using a Novel Fluorescence Assay. CDCA-NBD, OATP1B1 and OATP1B3
67  2020 beta-blockers Reverse Agonist-Induced beta2-AR Downregulation Regardless of Their Signaling Profile. beta-AR, ELISA
68  2020 Comprehensive characterization of dihydrofolate reductase-mediated gene amplification for the establishment of recombinant human embryonic kidney 293 cells producing monoclonal antibodies. DHFR/MTX, HP, mAb
69  2020 Cu/Zn Superoxide Dismutase (Sod1) regulates the canonical Wnt signaling pathway. CK1gamma, Wnt
70  2020 Drp1-mediated mitochondrial fission induced autophagy attenuates cell apoptosis caused by 3-chlorpropane-1,2-diol in HEK293 cells. Drp1
71  2020 Effect of amniotic fluid stem cell transplantation on the recovery of bladder dysfunction in spinal cord-injured rats. hAFSC, SCI
72  2020 Endothelin receptor heteromerization inhibits beta-arrestin function in HEK293 cells. BRET2, ERK, ET-1, ETA, ETB
73  2020 Ethylmalonic encephalopathy 1 initiates overactive autophagy in depleted uranium-induced cytotoxicity in the human embryonic kidney 293 cells. DU, ETHE1
74  2020 Food Additives as Inhibitors of Intestinal Drug Transporter OATP2B1. OATP2B1
75  2020 Glucokinase in stellate ganglia cooperates with P2X3 receptor to develop cardiac sympathetic neuropathy in type 2 diabetes rats. ATP, GCK, SG, shRNA, T2DM, TNF-alpha
76  2020 Glutathione depletion induces oxidative injury and apoptosis via TRPM2 channel activation in renal collecting duct cells. BSO, OS
77  2020 GRP Receptor Regulates Depression Behavior via Interaction With 5-HT2a Receptor. 5-HT2aR, CUMS, GRPR
78  2020 Haploinsufficiency of the Primary Familial Brain Calcification Gene SLC20A2 Mediated by Disruption of a Regulatory Element. Cas9, CRISPR, PFBC, RT-ddPCR
79  2020 Heterogeneous expression of plasma-membrane-localised OsOSCA1.4 complements osmotic sensing based on hyperosmolality and salt stress in Arabidopsis osca1 mutant. ---
80  2020 Heteromeric Kv7.2 current changes caused by loss-of-function of KCNQ2 mutations are correlated with long-term neurodevelopmental outcomes. BFNC, EE
81  2020 Human Bocavirus 1 Infection of Well-Differentiated Human Airway Epithelium. HAE-ALI, HBoV1
82  2020 Identification of Transient Receptor Potential Vanilloid 3 Antagonists from Achillea alpina L. and Separation by Liquid-Liquid-Refining Extraction and High-Speed Counter-Current Chromatography. 2-APB, HSCCC, TRPV3
83  2020 Imidazolium-based ionic liquid functionalized mesoporous silica nanoparticles as a promising nano-carrier: response surface strategy to investigate and optimize loading and release process for Lapatinib delivery. Lap
84  2020 Interplay Between Angiotensin II Type 1 Receptor and Thrombin Receptor Revealed by Bioluminescence Resonance Energy Transfer Assay. Ang II, AT1R, BRET, GPCRs, PAR1, RAS
85  2020 Japanese Herbal Medicine Ninjinyoeito Mediates Its Orexigenic Properties Partially by Activating Orexin 1 Receptors. GHS-R, GPCRs, NPY1R, NYT, OX1R
86  2020 Large-Scale Production of Recombinant Noggin and R-Spondin1 Proteins Required for the Maintenance of Stem Cells in Intestinal Organoid Cultures. IMAC, mNoggin, mNoggin-His, mRSpo1, mRSpo1-Fc, PEI, VPA
87  2020 Light-Mediated Control over TRPC3-Mediated NFAT Signaling. NFAT, TRPC
88  2020 Loss of calpains-1 and -2 prevents repair of plasma membrane scrape injuries, but not small pores, and induces a severe muscular dystrophy. CAPN3
89  2020 Molecular Interaction Between Butorphanol and kappa-Opioid Receptor. KOR, N2A-mKOR-tdT
90  2020 Novel pathogenic mutations in minichromosome maintenance complex component 9 (MCM9) responsible for premature ovarian insufficiency. MCM9, POI
91  2020 Novel Pt-Ag3PO4/CdS/Chitosan Nanocomposite with Enhanced Photocatalytic and Biological Activities. HeLa
92  2020 Nuclear Factor-kappaB Pathway Mediates the Molecular Pathogenesis of LMNA-Related Muscular Dystrophies. NF-kappaB
93  2020 OATP1B3 Expression and Function is Modulated by Coexpression with OCT1, OATP1B1, and NTCP. CCK-8, NTCP, OATP, OCT
94  2020 Peptide hormone sensors using human hormone receptor-carrying nanovesicles and graphene FETs. FETs, GCG, GCGR, GPCRs, PTH, PTHR
95  2020 pH-dependent pyridoxine transport by SLC19A2 and SLC19A3: Implications for absorption in acidic microclimates. MDCKII, THTR
96  2020 Pharmacological characterization of mono-, dual- and tri-peptidic agonists at GIP and GLP-1 receptors. GIP, GIPR, GLP-1, GLP-1R
97  2020 Pharmacological Premature Termination Codon Readthrough of ABCB11 in Bile Salt Export Pump Deficiency: An In Vitro Study. 4-PB, BSEP, NTCP, PFIC2
98  2020 Platycodin D suppresses cisplatin-induced cytotoxicity by suppressing ROS-mediated oxidative damage, apoptosis, and inflammation in HEK-293 cells. PD
99  2020 Preparation, Physicochemical Properties, and In Vitro Toxicity towards Cancer Cells of Novel Types of Arsonoliposomes. ARS, ARSL, DOX, LLC
100  2020 Protective effect of ginsenoside Rk1, a major rare saponin from black ginseng, on cisplatin-induced nephrotoxicity in HEK-293 cells. HO-1, MDA, Nrf2