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Abbreviation : HK
Long Form : hexokinase
No. Year Title Co-occurring Abbreviation
2021 A control theoretic three timescale model for analyzing energy management in mammalian cancer cells. ATP, glut1, HIF-1 alpha, SVR
2021 A hexokinase from the oyster Crassostrea gigas is involved in immune recognition as a pattern recognition receptor. ATP, LPS, ORF, PAMPs, PGN, PRR, rCgHK
2021 A Mechanistic Probe into the Dual Inhibition of T. cruzi Glucokinase and Hexokinase in Chagas Disease Treatment - A Stone Killing Two Birds? glk, Tc
2021 Diclofenac impairs the proliferation and glucose metabolism of triple-negative breast cancer cells by targeting the c-Myc pathway. CCK-8, GLUT1, TNBC
2021 Dose-dependent responses of metabolism and tissue injuries in clam Ruditapes philippinarum after subchronic exposure to cadmium. BMD, Cd, CS, NMR, SDH, TCA
2021 Early glycolytic reprogramming controls microglial inflammatory activation. 2-DG, 3-BPA, ELISA, GLUT1, IKKbeta, LPS, MPTP, mTOR, NF-kappaB, PD, RT-PCR, SIRT1, TH
2021 Effect of Increased IL-1β on Expression of HK in Alzheimer's Disease. AD, IL-1beta, LND, LPS, NIG, NLRP3, PET
2021 Effects of Microwave 10 GHz Radiation Exposure in the Skin of Rats: An Insight on Molecular Responses. CS, G6PD, LDH, MW
2021 Environmentally relevant concentrations of tralopyril affect carbohydrate metabolism and lipid metabolism of zebrafish (Danio rerio) by disrupting mitochondrial function. ATP, SDH, TP
10  2021 Exploring the Mechanism of the miRNA-145/Paxillin Axis in Cell Metabolism During VEGF-A-Induced Corneal Angiogenesis. GLUT1, HUVECs, mTOR, PI3K, PXN, VEGFA
11  2021 Expression of Hexokinase in the Proteome Profile of Leishmania major and Crithidia CL, PCR
12  2021 Extracellular Vesicle Transmission of Chemoresistance to Ovarian Cancer Cells Is Associated with Hypoxia-Induced Expression of Glycolytic Pathway Proteins, and Prediction of Epithelial Ovarian Cancer Disease Recurrence. 6PGL, MRM, OvCar
13  2021 Functions of Forkhead Box O on Glucose Metabolism in Abalone Haliotis discus hannai and Its Responses to High Levels of Dietary Lipid. FH, FOXO, G6Pase, PK
14  2021 GLUT5 (SLC2A5) enables fructose-mediated proliferation independent of ketohexokinase. KHK
15  2021 Hepatitis B virus rigs the cellular metabolome to avoid innate immune recognition. HBV, RIG-I
16  2021 Impact of Hypoxic Exercise Recovery on Skeletal Muscle Glycogen and Gene Expression. COX, FIS1, HIF, Mfn-2, OPA-1, PFK, PGC-1alpha
17  2021 Infrequent metadynamics study of rare-event electrostatic channeling. G6P, InMetaD, KMC, US
18  2021 Key Regulators of Sucrose Metabolism Identified through Comprehensive Comparative Transcriptome Analysis in Peanuts. CIN, CWIN, DEGs, FBA, FBP, PGI, RILs, SPP, SUS, SWEETs, TFs, VIN, WGCNA
19  2021 Nutritional Effects of the Enteral Nutritional Formula on Regulation of Gut Microbiota and Metabolic Level in Type 2 Diabetes Mellitus Mice. EN, Glut2, PK, SPG, STZ/HFD, T2DM
20  2021 Production of Glucose 6-Phosphate From a Cellulosic Feedstock in a One Pot Multi-Enzyme Synthesis. PPK2
21  2021 Proteomics analysis as an approach to understand the formation of pale, soft, and exudative (PSE) pork. CK, LDH, PK, PSE
22  2021 Soybean protein concentrate as a protein source for totoaba (Totoaba macdonaldi) juveniles: Effect on intermediary metabolism and liver histological organization. FM, GK, RD, SPC
23  2021 Transcriptional response of key metabolic and stress response genes of a nuculanid bivalve, Lembulus bicuspidatus from an oxygen minimum zone exposed to hypoxia-reoxygenation. OMZ, PEPCK
24  2021 Trehalose alleviates high-temperature stress in Pleurotus ostreatus by affecting central carbon metabolism. G6PDH, NADPH, OCR, PFK, PK, PPP, TPS1
25  2021 [Study on malignant transformation of MeT-5A cells induced by chrysotile]. LDH, PFK, PK
26  2020 A pan-cancer analysis of molecular characteristics and oncogenic role of hexokinase family genes in human tumors. ---
27  2020 alpha-Lipoic Acid Maintains Brain Glucose Metabolism via BDNF/TrkB/HIF-1alpha Signaling Pathway in P301S Mice. AD, BDNF, GLUT3, HIF-1alpha, HO-1, LA, PGC-1alpha, TrkB, VEGF
28  2020 C16:0 ceramide effect on melanoma malignant behavior and glycolysis depends on its intracellular or exogenous location. LDH, PK
29  2020 Cardiac expression and location of hexokinase changes in a mouse model of pure creatine deficiency. AGAT, AK, CK, GAMT, KO
30  2020 Characterization, Knockdown and Parental Effect of Hexokinase Gene of Cnaphalocrocis medinalis (Lepidoptera: Pyralidae) Revealed by RNA Interference. ---
31  2020 Chronic exposure to environmental cadmium affects growth and survival, cellular stress, and glucose metabolism in juvenile channel catfish (Ictalurus punctatus). G6P, GAPDH, HSP, MT, SF-1, StAR
32  2020 Copper-Induced Activation of MAPKs, CDPKs and CaMKs Triggers Activation of Hexokinase and Inhibition of Pyruvate Kinase Leading to Increased Synthesis of ASC, GSH and NADPH in Ulva compressa. ASC, G6PDH, GS, HP, PK, SA
33  2020 Effect of long-term treatment of Carvacrol on glucose metabolism in Streptozotocin-induced diabetic mice. ALP, AST, BW, CS, i.p, LDH, PFK, STZ, TC, TG
34  2020 Effects and mechanisms of fatty acid metabolism‑mediated glycolysis regulated by betulinic acid‑loaded nanoliposomes in colorectal cancer. ACSL, BA, CPT, CRC, PK, PKM2
35  2020 Effects of different dietary carbohydrate-to-lipid ratios on growth, plasma biochemical indexes, digestive, and immune enzymes activities of sub-adult orange-spotted grouper Epinephelus coioides. ACP, AKP, CHO, Chol, FCR, G6PDH, GLU, LYZ, PER, SGR, SOD, TG, WGR
36  2020 Effects of nanoplastics on energy metabolism in the oriental river prawn (Macrobrachium nipponense). ACBP, ACC, FABP 10, G-6-Pase, LDH, PK
37  2020 Glucose metabolism pattern of peripheral blood immune cells in myasthenia gravis patients. DCs, MG, PBMCs, PFK, PK, Th
38  2020 Hemocyte extracellular traps of Manila clam Ruditapes philippinarum: Production characteristics and antibacterial effects. ERK, ETs, GLUT, MPO, NADPH, PI3K, PK, ROS, SEM
39  2020 Hexokinase 2 Promotes Cell Growth and Tumor Formation Through the Raf/MEK/ERK Signaling Pathway in Cervical Cancer. HK2, SCC
40  2020 High Carbon Dioxide Treatment Modulates Sugar Metabolism and Maintains the Quality of Fresh-Cut Pear Fruit. AI, FK, NAD-SDH, NI, SOX, SPS, SS, TSS
41  2020 Human haptoglobin contributes to breast cancer oncogenesis through glycolytic activity modulation. GPI, Hp
42  2020 Hydrogen cyanamide induces grape bud endodormancy release through carbohydrate metabolism and plant hormone signaling. ABA, AM, BM, CAT, DEGs, FK, GBSS, GO, GSH-Px, IAA, INV, KEGG, PAO, PAOX, POD, SOD, SPS, SS, SUS, ZT
43  2020 Impact of Two Different Reference Measurement Procedures on Apparent System Accuracy of 18 CE-Marked Current-Generation Blood Glucose Monitoring Systems. BGMS, GOD, MARD
44  2020 IRS-1/PI3K/Akt pathway and miRNAs are involved in whole grain highland barley (Hordeum vulgare L.) ameliorating hyperglycemia of db/db mice. G6Pase, GS, GSK-3beta, GSP, IRS-1, miRNA, PI3K, WGH
45  2020 Linker residues regulate the activity and stability of hexokinase 2, a promising anticancer target. CTD, HK2, NTD
46  2020 Metabolic responses of adult lion's paw scallops Nodipecten subnodosus exposed to acute hyperthermia in relation to seasonal reproductive effort. AEC, AK, ArgP, HX, IMP
47  2020 Newcastle disease virus suppress glycolysis pathway and induce breast cancer cells death. MOI, NDV
48  2020 Oxymatrine Inhibits Colorectal Cancer Metastasis via Attenuating PKM2-Mediated Aerobic Glycolysis. CRC, ECR, GLUT1, OCR, PFK, PKM2
49  2020 Protein synthesis inhibitors stimulate MondoA transcriptional activity by driving an accumulation of glucose 6-phosphate. ATP, G6P, mtATP, PDxO, RocA, TNBC, TXNIP, VDAC
50  2020 Regulatory Role of Hexokinase 2 in Modulating Head and Neck Tumorigenesis. HNSCC, OXPHOS
51  2020 Synergistic Effect of 3-Bromopyruvate in Combination with Rapamycin Impacted Neuroblastoma Metabolism by Inhibiting Autophagy. 3-BrPA, CCK-8, NB, q-PCR, WB
52  2020 The effect of candesartan on chronic stress induced imbalance of glucose homeostasis. G6P, GK, GLUT2, GR, GS, ISR, LDH, RAS, SDH
53  2020 Toxicity and metabolism of 3-bromopyruvate in Caenorhabditis elegans. 3-BrPA, NGM, qPCR, RNAi
54  2020 VDAC upregulation and αTAT1‑mediated α‑tubulin acetylation contribute to tanespimycin‑induced apoptosis in Calu‑1 cells. alphaTAT1, ANT, GSK-3beta, IP, MOM, VDAC1
55  2020 Warmer temperature increases mercury toxicity in a marine copepod. GPx, HSP70, MSF, MT-1, PK, SOD
56  2019 A potential probiotic Chromobacterium aquaticum with bacteriocin-like activity enhances the expression of indicator genes associated with nutrient metabolism, growth performance and innate immunity against pathogen infections in zebrafish (Danio rerio). G6Pase, GHR, GK, IGF-1
57  2019 A Tumor Agnostic Therapeutic Strategy for Hexokinase 1-Null/Hexokinase 2-Positive Cancers. ---
58  2019 A Warburg effect targeting vector designed to increase the uptake of compounds by cancer cells demonstrates glucose and hypoxia dependent uptake. ---
59  2019 Ca2+-Calcineurin-NFAT pathway mediates the effect of thymol on oxidative metabolism and fiber-type switch in skeletal muscle. LDH, SDH
60  2019 Continuous Inking Affects the Biological and Biochemical Responses of Cuttlefish Sepia pharaonis. AK, MDA, PK, SOD
61  2019 Deoxyelephantopin suppresses hepatic stellate cells activation associated with inhibition of aerobic glycolysis via hedgehog pathway. ASMA, DET, GLUT4, Hh, HSCs, PFK-2
62  2019 Effects of Centella asiatica on skeletal muscle structure and key enzymes of glucose and glycogen metabolism in type 2 diabetic rats. CA, FBPase, GP, GS, PFK, T2DM
63  2019 Effects of copper toxicity at different pH and temperatures on the in vitro enzyme activity in blood and liver of fish, Prochilodus lineatus. G6PDH, LDH, PFK, PK
64  2019 Effects of short-term fasting on the resistance of Nile tilapia (Oreochromis niloticus) to Streptococcus agalactiae infection. CAT, IL-1beta, PEPCK, PK, SOCS1, SOD
65  2019 Effects of stanniocalcin hormones on rat brown adipose tissue metabolism under fed and fasted conditions. BAT, Stc1, STC2
66  2019 EGF receptor stimulation shifts breast cancer cell glucose metabolism toward glycolytic flux through PI3 kinase signaling. EGF, FDG, GLUT1, MAPK, PI3K
67  2019 Emerging roles of aerobic glycolysis in breast cancer. AMPK, BC, GLUTs, mTOR, PFK, PK
68  2019 Enzymatic and Structural Characterization of the Naegleria fowleri Glucokinase. Glck, NfGlck
69  2019 Exposure to ambient fine particles causes abnormal energy metabolism and ATP decrease in lung tissues. CS, MDH
70  2019 Glucose Utilization in the Regulation of Chitin Synthesis in Brown Planthopper. G6Pase
71  2019 Hexokinase-II Inhibition Synergistically Augments the Anti-tumor Efficacy of Sorafenib in Hepatocellular Carcinoma. 3-BP, HCC
72  2019 MicroRNA-124 regulates lactate transportation in the muscle of largemouth bass (micropterus salmoides) under hypoxia by targeting MCT1. DO, LDH, PEPCK, PFK, PK
73  2019 Mitochondria-coupled glucose phosphorylation develops after birth to modulate H2 O2 release and calcium handling in rat brain. ---
74  2019 Neuronostatin promotes soluble Abeta1-42 oligomers -induced spatial learning and memory impairments in mice. i.c.v, NST, SST
75  2019 Porphyromonas gingivalis triggers inflammatory responses in periodontal ligament cells by succinate-succinate dehydrogenase-HIF-1alpha axis. HIF-1alpha, IDH, SDH, TCA
76  2019 Rapid radiochemical filter paper assay for determination of hexokinase activity and affinity for glucose-6-phosphate. 2-DG, G6P, G6P
77  2019 Response of sugar metabolism in apple leaves subjected to short-term drought stress. A6PR, CWINV, FK, NINV, SDH, SPS, SuSy
78  2019 Responses of hemocyanin and energy metabolism to acute nitrite stress in juveniles of the shrimp Litopenaeus vannamei. FAS, LDH, PFK, PK, SDH, TG
79  2019 Seawater acidification increases copper toxicity: A multi-biomarker approach with a key marine invertebrate, the Pacific Oyster Crassostrea gigas. AChE, CI, CR, GST, IBR, LPO, OA, PK, RR, SOD
80  2019 Selenium impedes cadmium and arsenic toxicity in potato by modulating carbohydrate and nitrogen metabolism. AI, Cd, FK, GS, NI, nirA, NRA, PFK, PK, Se, SPS, SS, TSSC
81  2019 Structure and in vitro hypoglycemic activity of a homogenous polysaccharide purified from Sargassum pallidum. GLUT4, GS, IRS-1, PI3K, PK
82  2019 Sustained substrate cycles between hexose phosphates and free sugars in phosphate-deficient potato (Solanum tuberosum) cell cultures. ---
83  2019 Synergy between Auranofin and Celecoxib against Colon Cancer In Vitro and In Vivo through a Novel Redox-Mediated Mechanism. AF, CE, FDA
84  2019 Toxic effects of boscalid in adult zebrafish (Danio rerio) on carbohydrate and lipid metabolism. ACC, FAS, G6Pase, INS, SDH, SDHI, TG
85  2019 Type 2 diabetes differentially affects the substrate saturation kinetic attributes of erythrocyte hexokinase and phosphofructokinase. ATP, PFK
86  2019 [Lewis tumor cell conditioned medium enhances immunosuppressive function of mouse myeloid-derived suppressor cells by regulating glycolytic pathway]. Arg1, CFSE, GLUT1, HIF-1alpha, iNOS, LDHA, MDSCs, TCCM
87  2018 A precision therapeutic strategy for hexokinase 1-null, hexokinase 2-positive cancers. ---
88  2018 Amelioration by quercetin of insulin resistance and uterine GLUT4 and ERalpha gene expression in rats with polycystic ovary syndrome (PCOS). DHEA, ERalpha, GK, GLUT4, HOMA-IR, IR, PCOS
89  2018 Atrazine hinders PMA-induced neutrophil extracellular traps in carp via the promotion of apoptosis and inhibition of ROS burst, autophagy and glycolysis. ATR, Bax, Bcl-2, LC3B, MPO, mTOR, NETs, PFK, PMA, ROS
90  2018 cAMP Receptor Protein of Salmonella enterica Serovar Typhimurium Modulate Glycolysis in Macrophages to Induce Cell Apoptosis. S. Typhimurium
91  2018 Changes in secondary metabolites, organic acids and soluble sugars during the development of plum fruit cv. 'Furongli' (Prunus salicina Lindl). ACO, NAD-MDH, NADP-ME, PEPC, PGI
92  2018 Changes in the sucrose metabolism in apple fruit following postharvest acibenzolar-S-methyl treatment. AI, ASM, FK, NI, SPS, SS-c, SS-s
93  2018 Classical NF-kappaB Metabolically Reprograms Sarcoma Cells Through Regulation of Hexokinase 2. NF-kappaB, OS, RMS
94  2018 Effect of HK2, PKM2 and LDHA on Cetuximab efficacy in metastatic colorectal cancer. DCR, LDH, mCRC, ORR, OS, PFS, PKM
95  2018 Glycolysis inhibition via mTOR suppression is a key step in cardamonin-induced autophagy in SKOV3 cells. AMPK, LC3-II, LDH, MDC
96  2018 Hepatic HKDC1 Expression Contributes to Liver Metabolism. GCK, HKDC1, NAFLD
97  2018 Hexokinase as a versatile molecular genetic marker for Microsporidia. ---
98  2018 Human cellular mitochondrial remodelling is governed by miR-2909 RNomics. Bcl-2, GLUT1, NRF1, PBMCs, PGC1alpha, PPARgamma
99  2018 Influence of SIRT6 regulation of cellular glycometabolism on radiosensitivity of non-small-cell lung cancer A549 cells. LDHA, NSCLC, SF
100  2018 Linked Hexokinase and Glucose-6-Phosphatase Activities Reflect Grade of Ovarian Malignancy. FDG6P, G6Pase, PET