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Abbreviation : HSPCs
Long Form : hematopoietic stem and progenitor cells
No. Year Title Co-occurring Abbreviation
2021 3D Engineering of Human Hematopoietic Niches in Perfusion Bioreactor. BM, MSCs
2021 A 3-D hydrogel based system for hematopoietic differentiation and its use in modeling down syndrome associated transient myeloproliferative disorder. iPSCs, TMD
2021 A connexin/ifi30 pathway bridges HSCs with their niche to dampen oxidative stress. ROS
2021 A histone modifier, ASXL1, interacts with NONO and is involved in paraspeckle formation in hematopoietic cells. IDR
2021 A single-cell resolution developmental atlas of hematopoietic stem and progenitor cell expansion in zebrafish. CHT
2021 ACE2 gene transfer ameliorates vasoreparative dysfunction in CD34+ cells derived from diabetic older adults. ACE, ACE2, DB, HLI, LV
2021 Activated factor X targeted stored in platelets as an effective gene therapy strategy for both hemophilia A and B. FXa, HA
2021 Adult-repopulating lymphoid potential of yolk sac blood vessels is not confined to arterial endothelial cells. HECs, scRNA-seq, YS
2021 Advances and Obstacles in Homology-Mediated Gene Editing of Hematopoietic Stem Cells. ---
10  2021 Alternative polyadenylation dysregulation contributes to the differentiation block of acute myeloid leukemia. 3'READS, AML, APA, CDS, PAS, UTR
11  2021 An Early Myelosuppression in the Acute Mouse Sepsis Is Partly Outcome-Dependent. CLP, HSC, P-DIE, P-SUR
12  2021 An IDH1-vitamin C crosstalk drives human erythroid development by inhibiting pro-oxidant mitochondrial metabolism. alpha-KG, IDH1, OXPHOS, ROS
13  2021 Answered and Unanswered Questions in Early-Stage Viral Vector Transduction Biology and Innate Primary Cell Toxicity for Ex-Vivo Gene Editing. ---
14  2021 Arhgef2 regulates mitotic spindle orientation in hematopoietic stem cells and is essential for productive hematopoiesis. HSCs, SDS
15  2021 Ascorbic acid supports ex vivo generation of plasmacytoid dendritic cells from circulating hematopoietic stem cells. HSPC-pDCs, pDCs
16  2021 Assessment of Cellular Bioenergetics in Mouse Hematopoietic Stem and Primitive Progenitor Cells using the Extracellular Flux Analyzer. ECAR, HSCs, OCR, OXPHOS
17  2021 Autologous Ex Vivo Lentiviral Gene Therapy for Adenosine Deaminase Deficiency. ADA
18  2021 Base editing of haematopoietic stem cells rescues sickle cell disease in mice. SCD
19  2021 Bone marrow mesenchymal stromal cells in chronic myelomonocytic leukaemia: overactivated WNT/β-catenin signalling by parallel RNA sequencing and dysfunctional phenotypes. BMMSCs, CMML, HMAs, MDS, MPNs
20  2021 Bone Marrow Transplantation Procedures in Mice to Study Clonal Hematopoiesis. TBI
21  2021 Bortezomib enhances G-CSF-induced hematopoietic stem cell mobilization by decreasing CXCL12 levels and increasing vascular permeability. BM, BTZ, G-CSF
22  2021 CD74 is a regulator of hematopoietic stem cell maintenance. BM, HSCs, MIF
23  2021 Chronic interleukin-1 exposure triggers selection for Cebpa-knockout multipotent hematopoietic progenitors. IL-1beta
24  2021 Chronic lymphocytic leukemia B-cell-derived TNFα impairs bone marrow myelopoiesis. BM, CLL
25  2021 Clastogenicity and Aneugenicity of 1,4-Benzoquinone in Different Lineages of Mouse Hematopoietic Stem/Progenitor Cells. 1,4-BQ, CA, CFC, HPCs, MBMCs, Rb
26  2021 Clonal hematopoiesis and associated diseases: A review of recent findings. CHIP, CVD
27  2021 Combination of lentiviral and genome editing technologies for the treatment of sickle cell disease. LVs, SCD, VCN
28  2021 Comparative Analysis of the Genetic Variants in Haematopoietic Stem/Progenitor and Mesenchymal Stem Cell Compartments in de novo Myelodysplastic Syndromes. BM, MDS, MSCs
29  2021 Comparative Transcriptomic Analysis of the Hematopoietic System between Human and Mouse by Single Cell RNA Sequencing. ---
30  2021 Comprehensive RNA editome reveals that edited Azin1 partners with DDX1 to enable hematopoietic stem cell differentiation. A-to-I, AZIN1, DDX1
31  2021 Connection between Periodontitis-Induced Low-Grade Endotoxemia and Systemic Diseases: Neutrophils as Protagonists and Targets. NET, SLGI
32  2021 Continuous NF-κB pathway inhibition promotes expansion of human phenotypical hematopoietic stem/progenitor cells through metabolism regulation. ROS
33  2021 Controlled induction of immune tolerance by mesenchymal stem cells transferred by maternal microchimerism. MSCs, NIMAs
34  2021 Correction of X-CGD patient HSPCs by targeted CYBB cDNA insertion using CRISPR/Cas9 with 53BP1 inhibition for enhanced homology-directed repair. ROS
35  2021 Correction of β-thalassemia by CRISPR/Cas9 editing of the α-globin locus in human hematopoietic stem cells. ---
36  2021 CRISPR-targeted MAGT1 insertion restores XMEN patient hematopoietic stem cells and lymphocytes. AAV, GE, NK
37  2021 Danger-associated molecular pattern molecules take unexpectedly a central stage in Nlrp3 inflammasome-caspase-1-mediated trafficking of hematopoietic stem/progenitor cells. BM, ComC, DAMPs, IL-18, IL-1beta
38  2021 Development of LT-HSC-Reconstituted Non-Irradiated NBSGW Mice for the Study of Human Hematopoiesis In Vivo. HIS, HSC, LT-HSCs, NBSGW
39  2021 Development of β-globin gene correction in human hematopoietic stem cells as a potential durable treatment for sickle cell disease. rAAV6, SCD
40  2021 Diabetes Induces a Transcriptional Signature in Bone Marrow-Derived CD34+ Hematopoietic Stem Cells Predictive of Their Progeny Dysfunction. BM, CV, DM, GO BP, GSEA
41  2021 Disruption of a GATA2, TAL1, ERG regulatory circuit promotes erythroid transition in healthy and leukemic stem cells. AML
42  2021 Dissecting ELANE neutropenia pathogenicity by human HSC gene editing. NMD, SCN
43  2021 Distinct developmental pathways from blood monocytes generate human lung macrophage diversity. ---
44  2021 Distinct effects of chondroitin sulfate on hematopoietic cells and the stromal microenvironment in bone marrow hematopoiesis. BM, CS, ECs, MSCs, T1KO, WT
45  2021 Distinct profile of CD34+ cells and plasma-derived extracellular vesicles from triple-negative patients with Myelofibrosis reveals potential markers of aggressive disease. EVs, GEP, IL, MF, TN, TNF
46  2021 DL4-μbeads induce T cell lineage differentiation from stem cells in a stromal cell-free system. proT, PSCs
47  2021 DOT1L inhibitors block abnormal self-renewal induced by cohesin loss. AML
48  2021 Effective control of large deletions after double-strand breaks by homology-directed repair and dsODN insertion. AAV, DSBs, HDR, iPSCs, ssODNs
49  2021 Evaluation of a clinical-grade, cryopreserved, ex vivo-expanded stem cell product from cryopreserved primary umbilical cord blood demonstrates multilineage hematopoietic engraftment in mouse xenografts. allo-HSCT, cGMP, UCB, VPA
50  2021 Evaluation of glycolytic rates in human hematopoietic stem/progenitor cells after target gene depletion. ---
51  2021 Excessive R-loops trigger an inflammatory cascade leading to increased HSPC production. DDX41
52  2021 Extracellular Adenosine Triphosphate (eATP) and Its Metabolite, Extracellular Adenosine (eAdo), as Opposing "Yin-Yang" Regulators of Nlrp3 Inflammasome in the Trafficking of Hematopoietic Stem/Progenitor Cells. BM, eAdo, eATP, PB
53  2021 Facilitative lysosomal transport of bile acids alleviates ER stress in mouse hematopoietic precursors. ENT3, ER, ROS, TBA
54  2021 FDA-Approved Drug Screening for Compounds That Facilitate Hematopoietic Stem and Progenitor Cells (HSPCs) Expansion in Zebrafish. HSCs
55  2021 Fenofibrate increases circulating haematopoietic stem cells in people with diabetic retinopathy: a randomised, placebo-controlled trial. ---
56  2021 Fetal sheep support the development of hematopoietic cells in vivo from human induced pluripotent stem cells. HEs, iPSC
57  2021 Gene replacement of α-globin with β-globin restores hemoglobin balance in β-thalassemia-derived hematopoietic stem and progenitor cells. ---
58  2021 Genetic pathways regulating hematopoietic lineage speciation: Factorial latent variable model analysis of single cell transcriptome. f-scLVM
59  2021 Genome editing to model and reverse a prevalent mutation associated with myeloproliferative neoplasms. LT-HSCs, MPNs
60  2021 Genome editing using CRISPR/Cas9 to treat hereditary hematological disorders. DSBs, iPSCs
61  2021 Glucose oxidase induces mobilization of long-term repopulating hematopoietic cells in mice. BM, G-CSF, GO, ROS
62  2021 Glutamate-cysteine ligase catalytic subunit as a therapeutic target in acute myeloid leukemia and solid tumors. AML, GCLC
63  2021 GPX4 and vitamin E cooperatively protect hematopoietic stem and progenitor cells from lipid peroxidation and ferroptosis. GPX4, HSCs
64  2021 Grape seed proanthocyanidin extract ameliorates ionizing radiation-induced hematopoietic stem progenitor cell injury by regulating Foxo1 in mice. CAT, GSPE, HSCs, IR, ROS, SOD1, SOD2
65  2021 Group 2 innate lymphoid cells support hematopoietic recovery under stress conditions. 5-FU, BM, GM-CSF
66  2021 Heat-inactivated Escherichia coli promotes hematopoietic regeneration after irradiation with IL-1β. BM, HIEC
67  2021 Helios represses megakaryocyte priming in hematopoietic stem and progenitor cells. ---
68  2021 Hematopoietic stem and progenitor cells are present in healthy gingiva tissue. ---
69  2021 Hematopoietic stem and progenitor cells directly participate in host immune response. ---
70  2021 Hematopoietic stem progenitor cells lacking HLA differ from those lacking GPI-anchored proteins in the hierarchical stage and sensitivity to immune attack in patients with acquired aplastic anemia. AA, PB
71  2021 Heterogeneous disease-propagating stem cells in juvenile myelomonocytic leukemia. JMML, LSCs
72  2021 Histone methyltransferase Ezh2 negatively regulates NK cell terminal maturation and function. ---
73  2021 HIV-1LAI Nef blocks the development of hematopoietic stem/progenitor cells into T lymphoid cells. ---
74  2021 HSPCs display within-family homogeneity in differentiation and proliferation despite population heterogeneity. ---
75  2021 Human Microglia Extensively Reconstitute in Humanized-BLT Mice With Human Interleukin-34 Transgene and Support HIV-1 Brain Infection. hIL34 Tg, hu-BLT
76  2021 Hypoxia-Induced Alpha-Globin Expression in Syncytiotrophoblasts Mimics the Pattern Observed in Preeclamptic Placentas. PE
77  2021 Identification of unique microRNA expression patterns in bone marrow hematopoietic stem and progenitor cells after hemorrhagic shock and multiple injuries in young and old adult mice. BAL, BM, PNA, PT
78  2021 IL-6 contributes to metastatic switch via the differentiation of monocytic-dendritic progenitors into prometastatic immune cells. BM, GFP, GMPs, IL-6, MDPs, scRNA-seq
79  2021 Immunotherapeutic Potential of m6A-Modifiers and MicroRNAs in Controlling Acute Myeloid Leukaemia. AML, m5C, m6A, RMD
80  2021 Impact of cholesterol on proinflammatory monocyte production by the bone marrow. BM, FH, LDL-C
81  2021 Improved collection of hematopoietic stem cells and progenitors from Fanconi anemia patients for gene therapy purposes. BM, FA
82  2021 Improved Genome Editing through Inhibition of FANCM and Members of the BTR Dissolvase Complex. AAV-HR, Blm, DSB, FANCM, rAAV, RMI1, TI
83  2021 In vitro expansion of fetal liver hematopoietic stem cells. EPO, FLT-3, GM-CSF, IL-6, SCF
84  2021 In Vivo Tracking of Hematopoietic Stem and Progenitor Cell Ontogeny by Cellular Barcoding. ---
85  2021 Induction of AML Preleukemic Fusion Genes in HSPCs and DNA Damage Response in Preleukemic Fusion Gene Positive Samples. ALL, AML, PFGs, ROS, UCB
86  2021 iPSC modeling of stage-specific leukemogenesis reveals BAALC as a key oncogene in severe congenital neutropenia. AML, CN, CN/AML
87  2021 Loss of a 7q gene, CUX1, disrupts epigenetically driven DNA repair and drives therapy-related myeloid neoplasms. t-MNs
88  2021 Low Plasma Citrate Levels and Specific Transcriptional Signatures Associated with Quiescence of CD34+ Progenitors Predict Azacitidine Therapy Failure in MDS/AML Patients. AML-MRC, AZA, IDH, MDS, PD, RD
89  2021 Luspatercept restores SDF-1-mediated hematopoietic support by MDS-derived mesenchymal stromal cells. BMME, MDS, MSCs
90  2021 Lymphohematopoietic graft-versus-host responses promote mixed chimerism in patients receiving intestinal transplantation. GVH, GVHD, HVG
91  2021 Macrophage morphological plasticity and migration is Rac signalling and MMP9 dependant. ECM, MMPs
92  2021 Manufacturing a Bone Marrow-On-A-Chip Using Maskless Photolithography. BM
93  2021 Metabolic Analysis of Mouse Hematopoietic Stem and Progenitor Cells. ---
94  2021 Metabolic dysfunction induced by a high-fat diet modulates hematopoietic stem and myeloid progenitor cells in brown adipose tissue of mice. BAT, cDCs, cPTIO, DCs, UVR
95  2021 Metabolic sensor O-GlcNAcylation regulates megakaryopoiesis and thrombopoiesis through c-Myc stabilization and integrin perturbation. HSCs, MBs, MK, OGT
96  2021 Micro-RNA-125a mediates the effects of hypomethylating agents in chronic myelomonocytic leukemia. AZA, CMML, DEC, HMAs, miRs
97  2021 Modeling and live imaging of mechanical instabilities in the zebrafish aorta during hematopoiesis. DA, ECs, EHT
98  2021 Modulation of APLNR Signaling Is Required during the Development and Maintenance of the Hematopoietic System. mESC
99  2021 Mutation of Gemin5 Causes Defective Hematopoietic Stem/Progenitor Cells Proliferation in Zebrafish Embryonic Hematopoiesis. ---
100  2021 Myelodysplastic Syndromes in the Postgenomic Era and Future Perspectives for Precision Medicine. MDS