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Abbreviation : IGF-1R
Long Form : IGF-1 receptor
No. Year Title Co-occurring Abbreviation
2022 Actively targeted delivery of SN38 by ultrafine iron oxide nanoparticle for treating pancreatic cancer. IGF-1, uIONP
2022 Atractylodes chinensis volatile oil up-regulated IGF-1 to improve diabetic gastroparesis in rats. ACVO, DGP, ICCs, IGF-1, SCF
2022 Cixutumumab reveals a critical role for IGF-1 in adipose and hepatic tissue remodelling during the development of diet-induced obesity. HFD, IGF-1, WAT
2022 Defective IGF-1 prohormone N-glycosylation and reduced IGF-1 receptor signaling activation in congenital disorders of glycosylation. CDG, CTR, ER, IGF-1, proIGF-1Ea
2022 Effects of the Isolated and Combined Ablation of Growth Hormone and IGF-1 Receptors in Somatostatin Neurons. GH, IGF-1, SST
2022 Epo-IGF1R crosstalk expands stress-specific progenitors in regenerative erythropoiesis and myeloproliferative neoplasm. EPO, EPOR
2022 Expression of IGF-1 receptor and GH receptor in hepatic tissue of patients with nonalcoholic fatty liver disease and nonalcoholic steatohepatitis. BMI, GEA, GHR, IHC, NAFLD, NASH, NLH
2022 Fine-Tuning Cardiac Insulin-Like Growth Factor 1 Receptor Signaling to Promote Health and Longevity. IGF1
2022 Flotillin-1 palmitoylation turnover by APT-1 and ZDHHC-19 promotes cervical cancer progression by suppressing IGF-1 receptor desensitization and proteostasis. APT-1, EMT, FLOT1, IGF-1, PM, ZDHHC-19
10  2022 IGF1R inhibition enhances the therapeutic effects of Gq/11 inhibition in metastatic uveal melanoma progression. IGF1, NSG, UM
11  2022 Increased GH Secretion and Body Growth in Mice Carrying Ablation of IGF-1 Receptor in GH-releasing Hormone Cells. GH, GHRH, IGF-1
12  2022 Increased O-GlcNAcylation promotes IGF-1 receptor/PhosphatidyI Inositol-3 kinase/Akt pathway in cervical cancer cells. O-GlcNAcylation, OGA, PI-3K
13  2022 Insulin-like growth factor 1 regulates excitatory synaptic transmission in pyramidal neurons from adult prefrontal cortex. AMPAR, EPSC, IGF1, mGluR1, PFC
14  2022 Mini Review: Molecular Interpretation of the IGF/IGF-1R Axis in Cancer Treatment and Stem Cells-Based Therapy in Regenerative Medicine. IGF
15  2022 Transcriptomic Regulation of Muscle Mitochondria and Calcium Signaling by Insulin/IGF-1 Receptors Depends on FoxO Transcription Factors. IR, M-QKO, PKA
16  2022 Various phenotypes of short stature with heterozygous IGF-1 receptor (IGF1R) mutations. SGA
17  2022 Wounding Therapies for Prevention of Photocarcinogenesis. IGF-1, NMSC, UVB
18  2021 +3179G/A Insulin-Like Growth Factor-1 Receptor Polymorphism: A Novel Susceptibility Contributor in Anti-Ro/SSA Positive Patients with Sjogren's Syndrome: Potential Clinical and Pathogenetic Implications. HC, IGF, IHC, MSGs, SCs, SS
19  2021 Aerobic exercise and resistance exercise alleviate skeletal muscle atrophy through IGF-1/IGF-1R-PI3K/Akt pathway in mice with myocardial infarction. AE, HF, IGF-1, MI, MI, MRFs, PI3K, RE
20  2021 Age and insulin-like growth factor-1 impact PCNA monoubiquitination in UVB-irradiated human skin. IGF-1, TLS, UV
21  2021 Assessment of a New Nanostructured Microemulsion System for Ocular Delivery of Sorafenib to Posterior Segment of the Eye. IGF1, NaMESys, NF-kappaB, VEGFR1
22  2021 Cardiomyocyte protective effects of thyroid hormone during hypoxia/reoxygenation injury through activating of IGF-1-mediated PI3K/Akt signalling. I/R
23  2021 Caveolin-1 increases glycolysis in pancreatic cancer cells and triggers cachectic states. Cav-1, IGF-1, IR
24  2021 CRTC1/MAML2 directs a PGC-1α-IGF-1 circuit that confers vulnerability to PPARγ inhibition. CRTC1, IGF-1, MAML2, MEC, PGC-1alpha, PPARgamma
25  2021 Distinct signaling by insulin and IGF-1 receptors and their extra- and intracellular domains. IGF-1, IR, mTORC1
26  2021 Dynamic Regulation of GH-IGF1 Signaling in Injury and Recovery in Hyperoxia-Induced Neonatal Lung Injury. BPD, GH, GHR, IGF, pLFs
27  2021 Feeding Saccharomyces cerevisiae fermentation products lessens the severity of a viral-bacterial coinfection in preweaned calves. BRSV, IGF-1, PM, SCFP
28  2021 Growth Hormone/Insulin Growth Factor Axis in Sex Steroid Associated Disorders and Related Cancers. AR, ER, IGF, IGFBP
29  2021 Gypenoside XLIX protects against acute kidney injury by suppressing IGFBP7/IGF1R-mediated programmed cell death and inflammation. AKI, Gyp XLIX, IGFBP7
30  2021 Igf signaling couples retina growth with body growth by modulating progenitor cell division. CMZ
31  2021 IGF1-driven induction of GPCR kinase 2 in the primary afferent neuron promotes resolution of acute hyperalgesia. DRG, GPCR, IGF1
32  2021 IGF1R, IGFALS, and IGFBP3 gene copy number variations in a group of non-syndromic Egyptian short children. CNVs, IGF-1, MLPA
33  2021 IGF2 Mediates Resistance to Isoform-Selective-Inhibitors of the PI3K in HPV Positive Head and Neck Cancer. IGF2, isiPI3K, PI3K
34  2021 Inceptor counteracts insulin signalling in β-cells to control glycaemia. IGF1, IGF2R, INSR
35  2021 Insulin and IGF-1 receptors regulate complex I-dependent mitochondrial bioenergetics and supercomplexes via FoxOs in muscle. FoxO, IR, M-QKO, STZ
36  2021 Insulin Receptor in Pancreatic Cancer-Crown Witness in Cross Examination. IR
37  2021 Insulin-Like Growth Factor 1 in the Preterm Rabbit Pup: Characterization of Cerebrovascular Maturation following Administration of Recombinant Human Insulin-Like Growth Factor 1/Insulin-Like Growth Factor 1-Binding Protein 3. IGF-1, IVH, rh
38  2021 Insulin-Like Growth Factor-1 (IGF-1) and Its Monitoring in Medical Diagnostic and in Sports. GH, IGF-1, IGFBP-rPs, IGFBPs
39  2021 Insulin-like growth factor-1 induces IRE1-XBP1-dependent endoplasmic reticulum biogenesis in bovine mammary epithelial cells. 4mu8C, CHKA, ER, IGF-1, MEC, Surf4, XBP1s
40  2021 LRP1 mediates the IGF-1-induced GLUT1 expression on the cell surface and glucose uptake in Müller glial cells. GLUT1, IGF-1, LRP1, MGCs, PM
41  2021 M2‑like tumour‑associated macrophage‑secreted IGF promotes thyroid cancer stemness and metastasis by activating the PI3K/AKT/mTOR pathway. ATC, EMT, IGF, IHC, IR, TAMs
42  2021 Myocardial expression of somatotropic axis, adrenergic signalling, and calcium handling genes in heart failure with preserved ejection fraction and heart failure with reduced ejection fraction. GHR, HF, HFpEF, HFrEF
43  2021 Physiologic IGFBP7 levels prolong IGF1R activation in acute lymphoblastic leukemia. ALL, ERK, IGFBP-rP, IGFBPs, IGFs, IRS-1
44  2021 Pregnancy-associated plasma protein A mRNA expression as a marker for differentiated thyroid cancer: results from a "surgical" and a "cytological" series. FNAC, IGF1, IGFBP4, PAPPA
45  2021 Sustained Release of Insulin-Like Growth Factor-1 from Bombyx mori L. Silk Fibroin Delivery for Diabetic Wound Therapy. IGF-1, SF
46  2021 Targeted Liposomes Encapsulating miR-603 Complexes Enhance Radiation Sensitivity of Patient-Derived Glioblastoma Stem-Like Cells. IGF1, IR, miR-603, miRNA, PEG, PEI
47  2021 The growth hormone and insulin-like growth factor 1 axis in cattle during the peri-ovulatory period activates the synthesis and release of oviductal contraction related substances. BOECs, GH, GHR, IGF1, LH, mRNA
48  2021 The IGF-1 Signaling Pathway in Viral Infections. ERK, IGF-1, IRS, MAPK, PI3K, Shc
49  2021 The prevalence of secondary neoplasms in acromegalic patients: possible preventive and/or protective role of metformin. GH, IGF-1
50  2021 The Role of IGF/IGF-1R Signaling in Hepatocellular Carcinomas: Stemness-Related Properties and Drug Resistance. HBV, HCC, IGF, TKI
51  2021 The Role of Insulin-like Growth Factor-1 (IGF-1) in the Control of Neuroendocrine Regulation of Growth. IGF-1
52  2021 TNF-α-stimulated nucleus pulposus cells induce cell apoptosis through the release of exosomal miR-16 targeting IGF-1 and IGF-1R in rats. 3'UTRs, IGF-1, miRNAs, NPCs, PI3K, qRT-PCR, TNF-alpha
53  2021 Vitamin D3 induces mesenchymal-to-endothelial transition and promotes a proangiogenic niche through IGF-1 signaling. MEndoT, MSCs, VitD3
54  2021 ZYG11A Is Expressed in Epithelial Ovarian Cancer and Correlates With Low Grade Disease. EOC, GHR, IGF
55  2021 [Insulin-like growth factor 1 (IGF-1) promotes phagocytic activity of mouse BV-2 microglial cells via activating PI3K/AKT signaling pathway]. IGF-1, LPS
56  2020 Activation of beta1 integrins and caveolin-1 by TF/FVIIa promotes IGF-1R signaling and cell survival. ---
57  2020 Allopregnanolone Promotes Neuronal and Oligodendrocyte Differentiation In Vitro and In Vivo: Therapeutic Implication for Alzheimer's Disease. ALLO, IGF-1, NSCs
58  2020 Anti-inflammatory effect of IGF-1 is mediated by IGF-1R cross talk with GPER in MPTP/MPP+-induced astrocyte activation. COX-2, GPER, IGF-1, iNOS, MAPKs, MPTP, PI3K
59  2020 Cathepsin G-Induced Insulin-Like Growth Factor (IGF) Elevation in MCF-7 Medium Is Caused by Proteolysis of IGF Binding Protein (IGFBP)-2 but Not of IGF-1. CG, IGF, IGFBP, IGFBPs, IRS, NE
60  2020 Crucial role of androgen receptor in resistance and endurance trainings-induced muscle hypertrophy through IGF-1/IGF-1R- PI3K/Akt- mTOR pathway. AR, IGF-1, mTOR
61  2020 Effects of an anti-IGF-1 receptor monoclonal antibody on laminitis induced by prolonged hyperinsulinaemia in Standardbred horses. ---
62  2020 Effects of insulin on IGF-1 receptors in equine lamellar tissue in vitro. INSR, mAb
63  2020 Endothelial deficiency of insulin-like growth factor-1 receptor reduces endothelial barrier function and promotes atherosclerosis in Apoe-deficient mice. APOE, IGF-1
64  2020 Exposure to a Glyphosate-based Herbicide Alters the Expression of Key Regulators of Mammary Gland Development on Pre-pubertal Male Rats. AR, AREG, CCND1, EDCs, EGFR, GBH, IGF1, PND60
65  2020 Fermented Oyster Extract Promotes Insulin-Like Growth Factor-1-Mediated Osteogenesis and Growth Rate. dpf, PPP, zigf-1
66  2020 Flotillin and AP2A1/2 Promote IGF-1 Receptor Association with Clathrin and Internalization in Primary Human Keratinocytes. FLOT1
67  2020 Glutamate Attenuates the Survival Property of IGFR through NR2B Containing N-Methyl-D-aspartate Receptors in Cortical Neurons. IGF-1, NMDARs
68  2020 Identification of monoclonal antibodies suitable for blocking IGF-1 receptors in the horse. INSR, mAb
69  2020 IGF-1 receptor activity in the Golgi of migratory cancer cells depends on adhesion-dependent phosphorylation of Tyr1250 and Tyr1251. IGF-1, IR
70  2020 IGF-1R/mTOR Targeted Therapy for Ewing Sarcoma: A Meta-Analysis of Five IGF-1R-Related Trials Matched to Proteomic and Radiologic Predictive Biomarkers. ES, MDACC, mTORi, PFS
71  2020 IGF1R constitutive activation expands luminal progenitors and influences lineage differentiation during breast tumorigenesis. IGF, MECs
72  2020 Inhibition of SNCG suppresses the proliferation of lung cancer cells induced by high glucose. IGF-1, RT-q, SNCG
73  2020 Insulin-Like Growth Factor 1 Increases GABAergic Neurotransmission to GnRH Neurons via Suppressing the Retrograde Tonic Endocannabinoid Signaling Pathway in Mice. GnRH, IGF-1, mPSCs
74  2020 Insulin-like growth factor 1-receptor signaling stimulates GRP78 expression through the PI3K/AKT/mTOR/ATF4 axis. ---
75  2020 Is there a role for insulin-like growth factor inhibition in the treatment of COVID-19-related adult respiratory distress syndrome? ARDS, BAL
76  2020 Linagliptin Ameliorates Hepatic Steatosis via Non-Canonical Mechanisms in Mice Treated with a Dual Inhibitor of Insulin Receptor and IGF-1 Receptor. CYP2B10, IR, MUP20, NNMT, PLIN2
77  2020 Maternal Methyl-Donor Micronutrient Supplementation During Pregnancy Promotes Skeletal Muscle Differentiation and Maturity in Newborn and Weaning Pigs. 5-MTHF, CON, fast MyHC, IGF-1, MET, SAH, SAM
78  2020 Radiation-induced extracellular vesicle (EV) release of miR-603 promotes IGF1-mediated stem cell state in glioblastomas. CSC, EV, IGF1, IR, miRNA, umMGMT, wtIDH
79  2020 Reduced Insulin-Like Growth Factor Family Member Expression Predicts Neurogenesis Marker Expression in the Subependymal Zone in Schizophrenia and Bipolar Disorder. BDNF, EGF, FGF, IGF, IGFBP-2
80  2020 Short-term starvation reduces IGF-1 levels to sensitize lung tumors to PD-1 immune checkpoint blockade. IGF-1
81  2020 The Melatonin and Enriched Environment Ameliorated Low Protein-Induced Intrauterine Growth Retardation by IGF-1 And mtor Signaling Pathway and Autophagy Inhibition in Rats. EE, eIF4E, GH, GHRH, GHRH-R, IGF-1, IGFBP-1, IUGR, MEL, mTOR, S6K1, SST
82  2020 Unconventional Secretion of PKCdelta Exerts Tumorigenic Function via Stimulation of ERK1/2 Signaling in Liver Cancer. ER, PKCdelta
83  2019 Addition of zoledronic acid to neoadjuvant chemotherapy is not beneficial in patients with HER2-negative stage II/III breast cancer: 5-year survival analysis of the NEOZOTAC trial (BOOG 2010-01). DFS, IGF-1, OS, ZA
84  2019 Arrestin-beta-1 Physically Scaffolds TSH and IGF1 Receptors to Enable Crosstalk. ARRB1, GO, GO, HA, TSHRs
85  2019 Aspartame supplementation in starter accelerates small intestinal epithelial cell cycle and stimulates secretion of glucagon-like peptide-2 in pre-weaned lambs. BW, CDK6, GCG, GLP-2, GLP-2R, IGF-1, MTT
86  2019 Bad to the Bone: The Role of the Insulin-Like Growth Factor Axis in Osseous Metastasis. IGF
87  2019 Ceritinib-Induced Regression of an Insulin-Like Growth Factor-Driven Neuroepithelial Brain Tumor. ATO, IGF, INSR, NOTCH1, SHH, Wnt
88  2019 Effects of branched-chain volatile fatty acids and fibrolytic enzyme on rumen development in pre- and post-weaned Holstein dairy calves. BCVFA, BW, FE, GH, GHR, IGF-1
89  2019 Effects of Xiaotan Tongfu decoction on hepatic metastasis in obesity-associated colorectal cancer. CRC, IGF-1, IGFBP-3, XTTF
90  2019 Establishment of a novel human CIC-DUX4 sarcoma cell line, Kitra-SRS, with autocrine IGF-1R activation and metastatic potential to the lungs. IGF-1
91  2019 Exendin-4 enhances proliferation of senescent osteoblasts through activation of the IGF-1/IGF-1R signaling pathway. GLP-1, GLP-1R
92  2019 G protein-coupled estrogen receptor is involved in the neuroprotective effect of IGF-1 against MPTP/MPP+-induced dopaminergic neuronal injury. GPER, IGF-1, MAPK, PI3K, SN
93  2019 Growth hormone (GH) receptor (GHR)-specific inhibition of GH-Induced signaling by soluble IGF-1 receptor (sol IGF-1R). bGH, GH, GHR, PRL, sol IGF-1R
94  2019 Growth Hormone Induces Colon DNA Damage Independent of IGF-1. GHR, PPP
95  2019 Human placental androgen receptor variants: Potential regulators of male fetal growth. AR, DHT, IGF-1, IGFBP-5, SGA
96  2019 Immunological Aspects of Graves' Ophthalmopathy. GAG, GD, TSHR
97  2019 Insulin-like growth factor 1 signaling in tenocytes is required for adult tendon growth. Scx
98  2019 Insulin-like growth factor 2 promotes the adipogenesis of hemangioma-derived stem cells. HemSC, IGF2, IH, p-Akt, PI3K
99  2019 Insulin-Like Growth Factor and SLC12A7 Dysregulation: A Novel Signaling Hallmark of Non-Functional Adrenocortical Carcinoma. ACC, CNV, IGF
100  2019 Insulin-like growth factor-1 directly mediates expression of mitochondrial uncoupling protein 3 via forkhead box O4. FOXO4, IGF-1, PI3, UCP3