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Abbreviation : IL-16
Long Form : interleukin-16
No. Year Title Co-occurring Abbreviation
2022 Association of a miRNA-binding site polymorphism in IL-16 gene with disease risk and clinical characteristics of rheumatoid arthritis and systemic lupus erythematosus. HRM, miRNAs, RA, SLE, SNPs
2022 Association of Sarcopenia and Expression of Interleukin-16 in Gastric Cancer Survival. CI, GC, HR, OS, RFS
2022 Changes in IL-16 Expression in the Ovary during Aging and Its Potential Consequences to Ovarian Pathology. FSH, miR
2022 CIITA expression is regulated by histone deacetylase enzymes and has a role in alpha-synuclein pre-formed fibril-induced antigen presentation in murine microglial cell line. CIITA, HDACi, MHC-II, PD, pFF alpha-synuclein
2022 Correlation of Serum Levels of Interleukine-16, CCL27, Tumor Necrosis Factor-related Apoptosis-inducing Ligand, and B-cell Activating Factor with Multiple Sclerosis Severity. EDSS, MS, TRAIL
2022 Electroacupuncture of the Baihui and Shenting acupoints for vascular dementia in rats through the miR-81/IL-16/PSD-95 pathway. EA, IHC, miR-81, non-AP, OGD/R, PSD-95, qRT-PCR, si, TUNEL, VaD
2022 Genetically Predicted Levels of Circulating Inflammatory Cytokines and the Risk and Age at Onset of Parkinson's Disease: A Two-Sample Mendelian Randomization Study. GWASs, IVW, MIP-1b, MR, MR-PRESSO, PD
2022 Novel model for chronic intestinal inflammation in chickens: (2) Immunologic mechanism behind the inflammatory response. CCL20, CNT, IFN-alpha, M-CSF, NSP, VEGF
2022 Role of Inflammatory Factors in Mediating the Effect of Lipids on Nonalcoholic Fatty Liver Disease: A Two-Step, Multivariable Mendelian Randomization Study. ApoA1, apoB, GWAS, HDL-C, IL-17, IL-18, IL-1beta, IL-6, IVW, LDL-C, MR, NAFLD, TGs
10  2022 The Increase in Circulating Levels of Pro-Inflammatory Chemokines, Cytokines, and Complement C5 in Canines with Impaired Kidney Function. CXCL5
11  2021 A Machine Learning Explanation of the Pathogen-Immune Relationship of SARS-CoV-2 (COVID-19), and a Model to Predict Immunity and Therapeutic Opportunity: A Comparative Effectiveness Research Study. AUROC, M-CSF, RT-PCR, SCGF-beta
12  2021 A teleost interleukin-16 is implicated in peripheral blood leukocytes recruitment and anti-bacterial immunity. PBLs, rCsIL-16
13  2021 Anti-Interleukin-16-Neutralizing Antibody Attenuates Cardiac Inflammation and Protects against Cardiac Injury in Doxorubicin-Treated Mice. cTnT, LDH, nAb
14  2021 Downregulation of miR-1184 serves as a diagnostic biomarker in neonatal sepsis and regulates LPS-induced inflammatory response by inhibiting IL-16 in monocytes. LPS, miR-1184, NS
15  2021 Evaluation of circulating levels of Interleukin-10 and Interleukin-16 and dietary inflammatory index in Lebanese knee osteoarthritis patients. DKOA, IL-10, KOA, UKOA
16  2021 Expanded antigen-experienced CD160+CD8+effector T cells exhibit impaired effector functions in chronic lymphocytic leukemia. CLL, EVs
17  2021 Serum Inflammatory Factor Profiles in the Pathogenesis of High-Altitude Polycythemia and Mechanisms of Acclimation to High Altitudes. cHAPC, CMS, eHAPC, HAPC, IL-1beta, IL-2, IL-3, MCP-1, PC, PUC, TNF-alpha
18  2021 Urine Proteomics and Renal Single-Cell Transcriptomics Implicate Interleukin-16 in Lupus Nephritis. LN
19  2021 [Expression and clinical significance of interleukin-16 in patients with primary biliary cholangitis]. PBC
20  2020 Association of functional IL16 polymorphisms with cancer and cardiovascular disease: a meta-analysis. CVD, SNPs
21  2020 Association of IL-16 gene polymorphisms with sporadic Parkinson's disease in a Han Chinese population. LOPD, PD, SNPs
22  2020 BIOMARKERS OF DISEASE ACTIVITY IN SYSTEMIC SCLEROSIS. BNP, Cp, FSTL3, HSP27, KL-6, SELENOP, SRC, SSc
23  2020 Chronic Oral Palmitoylethanolamide Administration Rescues Cognitive Deficit and Reduces Neuroinflammation, Oxidative Stress, and Glutamate Levels in A Transgenic Murine Model of Alzheimer's Disease. AD, PEA, ROS
24  2020 Interaction of Interleukin-16 Genotypes With Betel Quid Chewing Behavior on Oral Cancer in Taiwan. PCR-RFLP
25  2020 MicroRNA-96 is Downregulated in Sepsis Neonates and Attenuates LPSInduced Inflammatory Response by Inhibiting IL-16 in Monocytes. miR-96, NS
26  2020 Polymorphisms in proinflammatory cytokines genes and susceptibility to Multiple Sclerosis. AS-PCR, CNS, EDSS, MS, MSSS, PCR-RFLP, TNF-alpha
27  2020 Synovial Fluid Interleukin-16 Contributes to Osteoclast Activation and Bone Loss through the JNK/NFATc1 Signaling Cascade in Patients with Periprosthetic Joint Infection. JNK, LPS, MAPK, NFATc1, PJI, TRAP
28  2019 Association of IL-16 gene polymorphisms with the risk of developing type 2 diabetes mellitus in the Chinese Han population. BMI, CIs, ORs, PCR-RFLP, SNPs, T2DM
29  2019 High-Dose Dexamethasone Alters the Increase in Interleukin-16 Level in Adult Immune Thrombocytopenia. HD-DXM, ITP
30  2019 Interleukin-16 aggravates ovalbumin-induced allergic inflammation by enhancing Th2 and Th17 cytokine production in a mouse model. BALF, OVA
31  2019 Interleukin-16 inhibits sodium channel function and GluA1 phosphorylation via CD4- and CD9-independent mechanisms to reduce hippocampal neuronal excitability and synaptic activity. ---
32  2019 Intervention for early diabetic nephropathy by mesenchymal stem cells in a preclinical nonhuman primate model. DN, MSCs
33  2019 Molecular cloning, characterization and expression analysis of S- adenosyl- L-homocysteine hydrolase (SAHH) during the pathogenic infection of Litopenaeus vannamei by Vibrio alginolyticus. ADO, Hcy, pI, SAH, SAHH, TLR
34  2019 Preliminary observation of chemokine expression in patients with Stanford type A aortic dissection. ENA-78, FLT3, IP-10, MCP, MIP-1beta, OPN, TAAD
35  2018 Ablation of the CD9 receptor in human lung cancer cells using CRISPR/Cas alters migration to chemoattractants including IL-16. ---
36  2018 Computational comparison of two new fusion proteins for multiple sclerosis. CNS, MBP, MOG, MS
37  2018 Elevated IL-16 expression is associated with development of immune dysfunction in children with autism. ASD, PBMCs, TD
38  2018 Genetic association between a single nucleotide polymorphism in Interleukin-16 (rs4072111) and susceptibility to chronic HCV infection in an Iranian population. PCR-RFLP
39  2018 Prospective evaluation of serum IL-16 and risk of prostate cancer in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial. ---
40  2018 Rs12976445 Polymorphism Is Associated with Post-Ablation Recurrence of Atrial Fibrillation by Modulating the Expression of MicroRNA-125a and Interleukin-6R. AF, LRAF, PCR
41  2018 Validation of Raised Cord Blood Interleukin-16 in Perinatal Asphyxia and Neonatal Hypoxic-Ischaemic Encephalopathy in the BiHiVE2 Cohort. ELISA, HIE, PA
42  2018 [IL-16 aggravates dextran sulfate sodium (DSS)-induced mouse inflammatory bowel disease by promoting M1 polarization of macrophages]. DSS, IBD
43  2017 Activation of silent mating type information regulation 2 homolog 1 by human chorionic gonadotropin exerts a therapeutic effect on hepatic injury and inflammation. AIH, FOXO3a, hCG, SIRT1
44  2017 Correction: Correlation of serum cartilage oligometric matrix protein (COMP) and interleukin-16 (IL-16) levels with disease severity in primary knee osteoarthritis: A pilot study in a Malaysian population. COMP
45  2017 Correlation of serum cartilage oligomeric matrix protein (COMP) and interleukin-16 (IL-16) levels with disease severity in primary knee osteoarthritis: A pilot study in a Malaysian population. COMP, KL, KOA, WOMAC
46  2017 Oscillating expression of interleukin-16 in multiple myeloma is associated with proliferation, clonogenic growth, and PI3K/NFKB/MAPK activation. MM
47  2017 RETRACTED ARTICLE: The Association of Interleukin-16 Gene Polymorphisms with IL-16 Serum Levels and Risk of Multiple Sclerosis. CNS, ELISA, MS, PCR-RFLP, SNPs
48  2017 [Expression profiles and clinical implication of plasma chemokines in patients with Stanford type A aortic dissection]. AD, CRP, ENA-78, FLT3, IP-10, MIP-1beta
49  2016 A Study on Genetic Association of Interleukin-16 Single Nucleotide Polymorphism (rs1131445) With Chronic Hepatitis B Virus Infection in Iranian Patients. PCR-RFLP
50  2016 Assessment of Interleukin 16 Serum Levels and Skin Expression in Psoriasis Patients in Correlation with Clinical Severity of the Disease. ---
51  2016 Association of interleukin-16 polymorphisms with disease progression and susceptibility in endometriosis. ---
52  2016 Body mass index, inflammatory biomarkers and neurocognitive impairment in HIV-infected persons. BMI, SE
53  2016 Clinical Usefulness of Simultaneous Measurement of the Tear Levels of CCL17, CCL24, and IL-16 for the Biomarkers of Allergic Conjunctival Disorders. ACDs, CCL17, ECP, TARC
54  2016 Endarterectomy patients with elevated levels of circulating IL-16 have fewer cardiovascular events during follow-up. CEA, CV, HR, PEA
55  2016 IL-16 rs4778889 polymorphism contribution to the development of renal cell cancer in a Chinese population. RCC
56  2016 Levels of interleukin-16 in peripheral blood of 52 patients with multiple myeloma and its clinical significance. AML, beta2-MG, CysC, LDH, MM
57  2016 Structure of a Potential Therapeutic Antibody Bound to Interleukin-16 (IL-16): MECHANISTIC INSIGHTS AND NEW THERAPEUTIC OPPORTUNITIES. IRI
58  2015 An Association Study on IL16 Gene Polymorphisms with the Risk of Sporadic Alzheimer's Disease. AD, LOAD
59  2015 Elevated plasma levels of interleukin-12p40 and interleukin-16 in overweight adolescents. BMI
60  2015 Genetic polymorphisms of interleukin-16 and risk of knee osteoarthritis. OA
61  2015 Genetic polymorphisms of interleukin-16 are associated with susceptibility to primary knee osteoarthritis. HW, OA, PCR-RFLP, SNPs
62  2015 Human Carotid Plaques With High Levels of Interleukin-16 Are Associated With Reduced Risk for Cardiovascular Events. ---
63  2015 Interleukin 16- (IL-16-) Targeted Ultrasound Imaging Agent Improves Detection of Ovarian Tumors in Laying Hens, a Preclinical Model of Spontaneous Ovarian Cancer. OvCa, TVUS
64  2015 Interleukin-16 gene polymorphisms are considerable host genetic factors for patients' susceptibility to chronic hepatitis B infection. HBV, RFLP, SNPs
65  2015 p21WAF1 Is Required for Interleukin-16-Induced Migration and Invasion of Vascular Smooth Muscle Cells via the p38MAPK/Sp-1/MMP-9 Pathway. VSMCs
66  2015 [Increased expression of IL-16 in mouse skin allograft]. ---
67  2014 Association of interleukin-16 polymorphisms with graves' disease in a Taiwanese population. GD, OR, SNPs
68  2014 CCR4+T cell recruitment to the skin in mycosis fungoides: potential contributions by thymic stromal lymphopoietin and interleukin-16. MF, TSLP
69  2014 Clostridium difficile toxin B inhibits the secretory response of human mast cell line-1 (HMC-1) cells stimulated with high free-Ca⁺ and GTPgammaS. Cm, HMC-1
70  2014 Interferon beta-1a reduces increased interleukin-16 levels in multiple sclerosis patients. MOG, MS
71  2014 Positive association between IL-16 rs11556218 T/G polymorphism and cancer risk: a meta-analysis. OR
72  2014 Secretion of IL-16 through TNFR1 and calpain-caspase signaling contributes to MRSA pneumonia. SpA, TNFR
73  2013 Association between IL16 gene polymorphisms and susceptibility to alopecia areata in the Korean population. AA, SNPs
74  2013 Integrative omics approach identifies interleukin-16 as a biomarker of emphysema. COPD, eQTL, PBMC
75  2013 Interleukin-16 gene polymorphisms rs4778889, rs4072111, rs11556218, and cancer risk in Asian populations: a meta-analysis. CIs, HWE, ORs
76  2013 Interleukin-16 polymorphism is associated with an increased risk of ischemic stroke. PCR-RFLP
77  2013 Interleukin-16 promotes cardiac fibrosis and myocardial stiffening in heart failure with preserved ejection fraction. CHF, LV
78  2013 Normative levels of Interleukin 16 in umbilical cord blood. HIE, UCB
79  2013 Regulation of cellular processes by interleukin-16 in homeostasis and cancer. CTCL, MM
80  2012 Association of interleukin 16 with the development of ovarian tumor and tumor-associated neoangiogenesis in laying hen model of spontaneous ovarian cancer. OvCa, TAN
81  2012 Cellular sources of interleukin 16 in benign and malignant pleural effusions. FCM, FCS, MCAS, PE, PMC
82  2012 Crucial role of CD4+CD 25+ FOXP3+ T regulatory cell, interferon-gamma and interleukin-16 in malignant and tuberculous pleural effusions. IFN-gamma, Treg
83  2012 Depletion of tristetraprolin in breast cancer cells increases interleukin-16 expression and promotes tumor infiltration with monocytes/macrophages. Mo, mRNAs, TTP
84  2012 Elevated serum IL-16 and RANTES levels in patients with autoimmune thyroid diseases and modulation by methimazole therapy. AITD, GD, HT, NTMNG
85  2012 High interleukin-16 concentrations in the early second trimester amniotic fluid: an independent predictive marker for preterm birth. AF, IL-18
86  2012 Induction of protective immunity against Eimeria tenella, Eimeria maxima, and Eimeria acervulina infections using dendritic cell-derived exosomes. DCs
87  2012 Methodologic issues in the measurement of interleukin-16 in clinical blood samples using immunoassays. ---
88  2012 Role of interleukin 16 in multiple myeloma. CI
89  2012 Serum interleukin-16 levels in patients with nasal polyposis. NP
90  2012 Two PDZ binding motifs within NS5 have roles in Tick-borne encephalitis virus replication. CASK, GIPC, GRIP2, PBMs, TBEV, WNV, ZO-2
91  2011 Association between interleukin-16 polymorphisms and risk of coronary artery disease. CAD
92  2011 Correlations of serum Interleukin-16, total IgE, eosinophil cationic protein and total eosinophil counts with disease activity in children with atopic dermatitis. AD, ECP, IgE, TEC
93  2011 Interleukin-16 (IL-16) gene polymorphisms in Iranian patients with colorectal cancer. CRC
94  2011 Introduction of pro-interleukin-16 inhibits T-lymphoblastic leukemia growth in mice. pro-IL-16
95  2010 A homologous form of human interleukin 16 is implicated in microglia recruitment following nervous system injury in leech Hirudo medicinalis. CNS
96  2010 Association of an interleukin-16 gene polymorphism with the risk and pain phenotype of endometriosis. ---
97  2010 Genetic factors in contact allergy--review and future goals. ACE, GST, NAT, TNF
98  2010 IL-16 effects on A549 lung epithelial cells: dependence on CD9 as an IL-16 receptor? ---
99  2010 IL-16 polymorphism and risk of renal cell carcinoma: association in a Chinese population. CI, OR, RCC
100  2010 Neutralization of interleukin-16 protects nonobese diabetic mice from autoimmune type 1 diabetes by a CCL4-dependent mechanism. ---