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Abbreviation : IgH
Long Form : Ig heavy chain
No. Year Title Co-occurring Abbreviation
2022 RNA exosome drives early B cell development via noncoding RNA processing mechanisms. Ig, ncRNAs
2021 Access to ultra-long IgG CDRH3 bovine antibody sequences using short read sequencing technology. Ig
2021 Clonality assessment and detection of clonal diversity in classic Hodgkin lymphoma by next-generation sequencing of immunoglobulin gene rearrangements. cHL, FFPE, HRS, Ig, NGS
2021 Dermatan Sulfate Is a Potential Regulator of IgH via Interactions With Pre-BCR, GTF2I, and BiP ER Complex in Pre-B Lymphoblasts. autoAg, DS
2021 IgH 3' regulatory region increases ectopic class switch recombination. 3'RR, AID, c3'RR, CSR, SHM
2021 Panorama of stepwise involvement of the IgH 3' regulatory region in murine B cells. 3'CBEs, CSR, GLT, Ig, SHM
2021 Plasma cell immunoglobulin heavy chain repertoire dynamics before and after tetanus booster vaccination. Ig, PBMC, PC
2020 Charting a DNA Repair Roadmap for Immunoglobulin Class Switch Recombination. AID, CSR, DSBs, Ig
2019 Clonality testing as complementary tool in the assessment of different patient groups with canine chronic enteropathy. CCE, CIBDAI, CO, FRD, IBD, PLE/IBD, TCRG
10  2019 Human colorectal cancer cells frequently express IgG and display unique Ig repertoire. Ig
11  2019 Kappa-on-Heavy (KoH) bodies are a distinct class of fully-human antibody-like therapeutic agents with antigen-binding properties. IGK, KoH, MBG
12  2019 Next-generation sequencing of immunoglobulin gene rearrangements for clonality assessment: a technical feasibility study by EuroClonality-NGS. Ig, NGS
13  2019 PCR GeneScan and Heteroduplex Analysis of Rearranged Immunoglobulin or T-Cell Receptor Genes for Clonality Diagnostics in Suspect Lymphoproliferations. Ig, IGK, PCR, TR, TRB, TRG
14  2019 Standardized IMGT Nomenclature of Salmonidae IGH Genes, the Paradigm of Atlantic Salmon and Rainbow Trout: From Genomics to Repertoires. AIRRseq, Ig
15  2019 The Immunoglobulins: New Insights, Implications, and Applications. Igs
16  2019 Two modes of cis-activation of switch transcription by the IgH superenhancer. ---
17  2018 DNA double-strand break response factors influence end-joining features of IgH class switch and general translocation junctions. ATM, C-NHEJ, CSR, DSBR, DSBs, MHs
18  2018 Functionally Convergent B Cell Receptor Sequences in Transgenic Rats Expressing a Human B Cell Repertoire in Response to Tetanus Toxoid and Measles Antigens. HTS, Ig, MVA, TT
19  2018 Physiological and druggable skipping of immunoglobulin variable exons in plasma cells. ASOs, Ig, NAS, PC
20  2017 BRCT-domain protein BRIT1 influences class switch recombination. AID, CSR, DSBs
21  2017 IgH isotype-specific B cell receptor expression influences B cell fate. BCRs
22  2017 Primary central nervous system extranodal nasal-type natural killer/T-cell lymphoma with CD20 expression. ---
23  2016 Characterization of a PCR-based lymphocyte clonality assay as a complementary tool for the diagnosis of feline lymphoma. Ig, TCR, TCRG
24  2016 Molecular clonality assessment shows high performance to predict malignant B-cell non-Hodgkin's lymphoma using cytological smears. FNAC, IGK
25  2016 Novel IGH and MYC Translocation Partners in Diffuse Large B-Cell Lymphomas. DLBCL, Ig
26  2016 Regulated large-scale nucleosome density patterns and precise nucleosome positioning correlate with V(D)J recombination. RAG, RSS
27  2016 Sequential activation and distinct functions for distal and proximal modules within the IgH 3' regulatory region. KO
28  2015 CTCF-binding elements 1 and 2 in the Igh intergenic control region cooperatively regulate V(D)J recombination. CTCF, IGCR1
29  2015 Molecular Mechanisms of IgE Class Switch Recombination. C mu, CSR, Ig
30  2015 New roles for DNA cytosine modification, eRNA, anchors, and superanchors in developing B cell progenitors. CTCF
31  2015 The aryl hydrocarbon receptor regulates an essential transcriptional element in the immunoglobulin heavy chain gene. 3'IghRR, AhR, TCDD
32  2014 Expression and recruitment of uracil-DNA glycosylase are regulated by E2A during antibody diversification. AID, Ig
33  2014 Immunoglobulin expressions are only associated with MCPyV-positive Merkel cell carcinomas but not with MCPyV-negative ones: comparison of prognosis. Ig, MCC, MCPyV, Oct-2, PAX5, SOX11
34  2014 Immunoglobulin heavy variable (IGHV) genes and alleles: new entities, new names and implications for research and prognostication in chronic lymphocytic leukaemia. CLL, IGHV, IMGT, SHM
35  2014 Sequencing of the human IG light chain loci from a hydatidiform mole BAC library reveals locus-specific signatures of genetic diversity. Ig, IGK
36  2014 VH Replacement Footprint Analyzer-I, a Java-Based Computer Program for Analyses of Immunoglobulin Heavy Chain Genes and Potential VH Replacement Products in Human and Mouse. VHRFA-I
37  2014 Zinc-finger protein ZFP318 is essential for expression of IgD, the alternatively spliced Igh product made by mature B lymphocytes. ---
38  2013 PCR-based analysis of rearranged immunoglobulin or T-cell receptor genes by GeneScan analysis or heteroduplex analysis for clonality assessment in lymphoma diagnostics. Ig, IGK, PCR, TCR, TCRB, TCRG
39  2013 PCR-based clonality analysis in diffuse large B-cell lymphoma using BIOMED-2 primers of IgH (FR3) on formalin-fixed paraffin-embedded tissue. DLBCL, FFPE, FR3, Ig, PCR
40  2012 Reprogramming IgH isotype-switched B cells to functional-grade induced pluripotent stem cells. CSR, iPSCs
41  2012 Robust chromosomal DNA repair via alternative end-joining in the absence of X-ray repair cross-complementing protein 1 (XRCC1). A-EJ, C-NHEJ, CSR, DSB, LIG1, LIG3, LIG4, XRCC1
42  2011 Cross talk between immunoglobulin heavy-chain transcription and RNA surveillance during B cell development. Ig, NMD, RNAPII
43  2011 High-throughput VDJ sequencing for quantification of minimal residual disease in chronic lymphocytic leukemia and immune reconstitution assessment. CLL, HCT, HTS, MRD
44  2011 Hydrogen peroxide modulates immunoglobulin expression by targeting the 3'Igh regulatory region through an NFkappaB-dependent mechanism. 3'IghRR, Ig
45  2011 Somatic hypermutation leads to diversification of the heavy chain immunoglobulin repertoire in cattle. Ig
46  2011 Translocation of an antibody transgene requires AID and occurs by interchromosomal switching to all switch regions except the mu switch region. AID, CSR, Ig
47  2010 Downstream class switching leads to IgE antibody production by B lymphocytes lacking IgM switch regions. AID, CSR, DSBs, ISD
48  2010 Elements between the IgH variable (V) and diversity (D) clusters influence antisense transcription and lineage-specific V(D)J recombination. TCR
49  2010 Immunoglobulin genes and their transcriptional control in teleosts. Ig
50  2009 Detection of clonal immunoglobulin and T-cell receptor gene recombination in hematological malignancies: monitoring minimal residual disease. Ig, IGK, IGL, MRD, PCR, TCR
51  2009 Diverse chemicals including aryl hydrocarbon receptor ligands modulate transcriptional activity of the 3'immunoglobulin heavy chain regulatory region. 3'IgHRR, AhR, DRE, TCDD
52  2009 H3 trimethyl K9 and H3 acetyl K9 chromatin modifications are associated with class switch recombination. AID, CSR
53  2009 Immunoglobulin gene transcripts have distinct VHDJH recombination characteristics in human epithelial cancer cells. Ig
54  2009 Integrity of the AID serine-38 phosphorylation site is critical for class switch recombination and somatic hypermutation in mice. AID, CSR, RPA, SHM, ss
55  2008 Antisense transcripts from immunoglobulin heavy-chain locus V(D)J and switch regions. AID, CSR, SHM
56  2008 Use of IGHV3-21 in chronic lymphocytic leukemia is associated with high-risk disease and reflects antigen-driven, post-germinal center leukemogenic selection. CLL, CRC, Ig, IGHV, IgL
57  2007 Nonstochastic pairing of immunoglobulin heavy and light chains expressed by chronic lymphocytic leukemia B cells is predicated on the heavy chain CDR3. CLL, HCDR3, Ig, IgL
58  2007 Replacement of Igamma3 germ-line promoter by Igamma1 inhibits class-switch recombination to IgG3. CSR, GL
59  2006 Mechanism and control of V(D)J recombination at the immunoglobulin heavy chain locus. Ig
60  2005 Discovery of a unique Ig heavy-chain isotype (IgT) in rainbow trout: Implications for a distinctive B cell developmental pathway in teleost fish. BAC, tau
61  2005 Elucidation of IgH intronic enhancer functions via germ-line deletion. cEmu
62  2005 Evolution of class switch recombination function in fish activation-induced cytidine deaminase, AID. AID, CSR, SHM
63  2004 Complex biallelic IGH rearrangements in IgM-expressing Z-138 cell line: Involvement of downstream immunoglobulin class switch recombination. CSR, FL, Ig
64  2004 Detection of monoclonality of the immunoglobulin heavy chain gene in thyroid malignant lymphoma by vectorette polymerase chain reaction. SBH
65  2003 E mu/S mu transposition into Myc is sometimes a precursor for T(12;15) translocation in mouse B cells. CSR, Ig, PCTs
66  2003 The biology and cytogenetics of multiple myeloma. MPC
67  2003 Use of a simple, general targeting vector for replacing the DNA of the heavy chain constant region in mouse hybridoma cells. Ig
68  2002 Extranodal marginal zone B-cell lymphoma of the lacrimal gland associated with crystal-storing histiocytosis. CSH, EMZL, Ig, PCR
69  2002 Genomic abnormalities in monoclonal gammopathy of undetermined significance. FISH, Ig, MGUS, MM, PCs
70  2002 Identification of E2A target genes in B lymphocyte development by using a gene tagging-based chromatin immunoprecipitation system. ---
71  2002 Interphase FISH assays for the detection of translocations with breakpoints in immunoglobulin light chain loci. FISH, Ig, IGK, IGL
72  2002 Minimal residual disease quantification in childhood acute lymphoblastic leukemia by real-time polymerase chain reaction using the SYBR green dye. ALL, Ig, MRD, NOPHO, RQ-PCR, TCR
73  2002 Site-specific translocation and evidence of postnatal origin of the t(1;19) E2A-PBX1 fusion in childhood acute lymphoblastic leukemia. TCR
74  2001 Analysis of clonal relationship using single-cell polymerase chain reaction in a patient with concomitant mantle cell lymphoma and multiple myeloma. Ig, MCL, MM
75  2001 Deletional analyses reveal an essential role for the hs3b/hs4 IgH 3' enhancer pair in an Ig-secreting but not an earlier-stage B cell line. ---
76  2001 Detailed clonality analysis of relapsing precursor B acute lymphoblastic leukemia: implications for minimal residual disease detection. Ig, MRD, TCR
77  2001 Novel control motif cluster in the IgH delta-gamma 3 interval exhibits B cell-specific enhancer function in early development. ---
78  2000 Diagnosis of thyroid malignant lymphoma by reverse transcription-polymerase chain reaction detecting the monoclonality of immunoglobulin heavy chain messenger ribonucleic acid. mRNA, RNAs
79  2000 DNA double-strand breaks in immunoglobulin genes undergoing somatic hypermutation. DSBs, GC, Ig
80  2000 Molecular aspects of multiple myeloma. HHV-8, Ig, MM
81  2000 The characteristics of Epstein-Barr virus (EBV)-positive diffuse large B-cell lymphoma: comparison between EBV(+) and EBV(-) cases in Japanese population. DLBCL, EBER1, EBNA2, EBV, GC, Ig, LMP1
82  1999 A novel stromal cell-dependent B lymphoid stem-like cell line that induces immunoglobulin gene rearrangement. HSA, Ig, IL
83  1999 Clonal rearrangements in childhood and adult precursor B acute lymphoblastic leukemia: a comparative polymerase chain reaction study using multiple sets of primers. ALL, FR, MRD, PCR, TCR
84  1999 Gene rearrangements in T-cell lymphoblastic lymphoma. ALL, TCRgamma
85  1999 High incidence of cryptic translocations involving the Ig heavy chain gene in multiple myeloma, as shown by fluorescence in situ hybridization. FISH, HMCL, MM, PCL
86  1999 Ig heavy chain expression and class switching in vitro from an allele lacking the 3' enhancers DNase I-hypersensitive hs3A and hs1,2. ---
87  1999 Position-dependent inhibition of class-switch recombination by PGK-neor cassettes inserted into the immunoglobulin heavy chain constant region locus. CSR, GT
88  1999 Recombination and transcription of the endogenous Ig heavy chain locus is effected by the Ig heavy chain intronic enhancer core region in the absence of the matrix attachment regions. RAG2
89  1998 A high frequency of circulating B cells share clonotypic Ig heavy-chain VDJ rearrangements with autologous bone marrow plasma cells in multiple myeloma, as measured by single-cell and in situ reverse transcriptase-polymerase chain reaction. G-CSF, MM, PBMC, RT-PCR
90  1998 Clonal analysis of intrahepatic B cells from HCV-infected patients with and without mixed cryoglobulinemia. HCV, MC, RF
91  1998 Late relapsing childhood lymphoblastic leukemia. PCR, TCR
92  1998 Mutation analysis of the rearranged immunoglobulin heavy chain genes of marginal zone cell lymphomas indicates an origin from different marginal zone B lymphocyte subsets. ---
93  1998 The fetal origin of B-precursor leukemia in the E-mu-ret mouse. ---
94  1997 Functional motifs in the IgH enhancer of the channel catfish. Emu
95  1997 Genetic recombinations between c-myc and Igh mu as precursors for recombinations between c-myc and Igh alpha in BALB/c plasmacytomas. ---
96  1997 Presence of B cell progenitors in the thymus. ---
97  1997 Rapid induction of B-cell lymphomas in mice carrying a human IgH/c-mycYAC. ES, Ig, YAC
98  1997 Rapid molecular cloning of rearrangements of the IGHJ locus using long-distance inverse polymerase chain reaction. LDI-PCR, MBR, mcr, PCR
99  1997 The Ig heavy chain gene is frequently involved in chromosomal translocations in multiple myeloma and plasma cell leukemia as detected by in situ hybridization. DC-FISH, MGUS, MM, YAC
100  1996 Analysis of clonal rearrangements of the Ig heavy chain locus in acute leukemia. BCP-ALL, FRIII, PCR