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[Related PubMed/MEDLINE] Total Number of Papers: 1152
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Abbreviation |
: KD |
Long Form |
: knockdown |
|
No. |
Year |
Title |
Co-occurring Abbreviation |
1 |
2023 |
A Plasmodium falciparum RING Finger E3 Ubiquitin Ligase Modifies the Roles of PfMDR1 and PfCRT in Parasite Drug Responses. |
GlcN, PfCRT, PfMDR1, PfRFUL |
2 |
2023 |
Biomolecular condensate assembly of nArgBP2 tunes its functionality to manifest the structural plasticity of dendritic spines. |
cLTP |
3 |
2023 |
Complement component 3 protects human bronchial epithelial cells from cigarette smoke-induced oxidative stress and prevents incessant apoptosis. |
AECs, COPD, CSE |
4 |
2023 |
Identification of Novel Pathways Regulated by APE1/Ref-1 in Human Retinal Endothelial Cells. |
--- |
5 |
2023 |
Ribosomal proteins regulate 2-cell-stage transcriptome in mouse embryonic stem cells. |
2C transcript, mESCs, RPs |
6 |
2023 |
RUNX2 stabilization by long non-coding RNAs contributes to hypertrophic changes in human chondrocytes. |
lncRNAs, OA, RNA-IP |
7 |
2023 |
Silencing TAB182 inhibits cell EMT, migration and invasion by downregulating EGFR in A549 NSCLC cells. |
IR, NSCLC |
8 |
2023 |
Transcriptome sequencing analysis of the role of β-catenin in F-actin reorganization in embryonic palatal mesenchymal cells. |
Cxcl5, DEGs, F-actin, GO, KEGG, MEPM, NC, qRT-PCR, SAA3 |
9 |
2022 |
A bidirectional competitive interaction between circHomer1 and Homer1b within the orbitofrontal cortex regulates reversal learning. |
circRNAs, OFC |
10 |
2022 |
A quantitative proteomic analysis reveals the potential roles of PRDX3 in neurite outgrowth in N2a-APPswe cells. |
AD, ANXA1, GO, GSTM2, PP2A, RA, Ser, TBHP, Thr, TMT |
11 |
2022 |
A Zebrafish/Drosophila Dual System Model for Investigating Human Microcephaly. |
KO |
12 |
2022 |
Accumbal adenosine A2A receptor inactivation biases for large and costly rewards in the effort- but not delay-based decision making. |
A2ARs, CBDM, D-CBDM, E-CBDM, ED, NAc, RD |
13 |
2022 |
Acid Adaptation Promotes TRPC1 Plasma Membrane Localization Leading to Pancreatic Ductal Adenocarcinoma Cell Proliferation and Migration through Ca2+ Entry and Interaction with PI3K/CaM. |
CaM, PDAC, TRPC1 |
14 |
2022 |
Active forgetting requires Sickie function in a dedicated dopamine circuit in Drosophila. |
AZ, BRP, DAn |
15 |
2022 |
Activity-dependent endoplasmic reticulum Ca2+ uptake depends on Kv2.1-mediated endoplasmic reticulum/plasma membrane junctions to promote synaptic transmission. |
ER, PM, VAP |
16 |
2022 |
ADAM10 and ADAM17-Novel Players in Retinoblastoma Carcinogenesis. |
ADAM, CAM, Rb |
17 |
2022 |
Adipose tissue cysteine dioxygenase type 1 is associated with an anti-inflammatory profile, impacting on systemic metabolic traits. |
CDO1, FEDER, SAT |
18 |
2022 |
Altered Biodistribution and Hepatic Safety Profile of a Gapmer Antisense Oligonucleotide Bearing Guanidine-Bridged Nucleic Acids. |
ASO, GuNA |
19 |
2022 |
An epigenetic mechanism for over-consolidation of fear memories. |
dmPFC-BLA |
20 |
2022 |
An unexpected role for tomato threonine deaminase 2 in host defense against bacterial infection. |
Ile, JA, PAMP, SA, TD |
21 |
2022 |
ANGPTL4 functions as an oncogene through regulation of the ETV5/CDH5/AKT/MMP9 axis to promote angiogenesis in ovarian cancer. |
ANGPTL4, IHC, OC, shRNAs |
22 |
2022 |
Arabidopsis ORP2A mediates ER-autophagosomal membrane contact sites and regulates PI3P in plant autophagy. |
ATG, EPCSs, ER, MCSs, ORP2A, PI3P, VAP |
23 |
2022 |
ARID1B, a molecular suppressor of erythropoiesis, is essential for the prevention of Monge's disease. |
CMS, EE |
24 |
2022 |
ARL6IP5 reduces cisplatin-resistance by suppressing DNA repair and promoting apoptosis pathways in ovarian carcinoma. |
CisR, OC, OE, rARL6IP5 |
25 |
2022 |
Beyond fusion: A novel role for ERVW-1 in trophoblast proliferation and type I interferon receptor expression. |
HERV, STB, TSC |
26 |
2022 |
Bitter Peptides YFYPEL, VAPFPEVF, and YQEPVLGPVRGPFPIIV, Released during Gastric Digestion of Casein, Stimulate Mechanisms of Gastric Acid Secretion via Bitter Taste Receptors TAS2R16 and TAS2R38. |
--- |
27 |
2022 |
BMAL1 modulates ROS generation and insulin secretion in pancreatic beta-cells: An effect possibly mediated via NOX2. |
DDC, GAPDH, KO, NOX, PEG-SOD, PMA, ROS |
28 |
2022 |
Brain-Derived Neurotrophic Factor Is an Important Therapeutic Factor in Mesenchymal Stem Cell Secretions for Treatment of Traumatic Peripheral Pelvic Injuries. |
BDNF, CCM, CM, LPP, MSCs, PNSBP |
29 |
2022 |
CD5 Controls Gut Immunity by Shaping the Cytokine Profile of Intestinal T Cells. |
NOD |
30 |
2022 |
CHAF1A/B mediate silencing of unintegrated HIV-1 DNAs early in infection. |
--- |
31 |
2022 |
Circ_0084043-miR-134-5p axis regulates PCDH9 to suppress melanoma. |
MMP-2, PCDH9, Pyk2, Rac1 |
32 |
2022 |
Claudin targeting as an effective tool for directed barrier modulation of the viable epidermis. |
GST-cCPE, RHE, TJ |
33 |
2022 |
Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer. |
AE, BC, ERalpha |
34 |
2022 |
Common Variation in EDN1 Regulatory Regions Highlights the Role of PPARgamma as a Key Regulator of Endothelin in vitro. |
EDN1, KLF4, PAECs, PAH, PPARgamma, SNP, TFs, UTR, VDR |
35 |
2022 |
Connexin 43 hemichannels regulate mitochondrial ATP generation, mobilization, and mitochondrial homeostasis against oxidative stress. |
HCs, mtCx43 |
36 |
2022 |
Connexin 43 Hemichannels Regulate Osteoblast to Osteocyte Differentiation. |
Cx43, HCs, OPG, RANKL |
37 |
2022 |
CRISPRi screening identifies CASP8AP2 as an essential viability factor in lung cancer controlling tumor cell death via the AP-1 pathway. |
CRISPRi, LUAD, TSS |
38 |
2022 |
CTR9 drives osteochondral lineage differentiation of human mesenchymal stem cells via epigenetic regulation of BMP-2 signaling. |
BMP-2, EZH2, hMSCs, PAFc |
39 |
2022 |
Cyclophilin D-mediated angiotensin II-induced NADPH oxidase 4 activation in endothelial mitochondrial dysfunction that can be rescued by gallic acid. |
Ang II, COVID-19, CsA, CypD, ERK, GA, HUVECs, NOX4 |
40 |
2022 |
CYP1B1 Augments the Mesenchymal, Claudin-Low, and Chemoresistant Phenotypes of Triple-Negative Breast Cancer Cells. |
CLDN, CYP1B1 |
41 |
2022 |
Cytosolic HMGB1 Mediates LPS-Induced Autophagy in Microglia by Interacting with NOD2 and Suppresses Its Proinflammatory Function. |
DAMP, HMGB1, LC3, LPS, NOD2 |
42 |
2022 |
D1 Receptor Mediated Dopaminergic Neurotransmission Facilitates Remote Memory of Contextual Fear Conditioning. |
D1Rs, DOX |
43 |
2022 |
DAP5 drives translation of specific mRNA targets with upstream ORFs in human embryonic stem cells. |
ESCs, hESCs, uORFs |
44 |
2022 |
Differential requirements for different subfamilies of the mammalian SWI/SNF chromatin remodeling enzymes in myoblast cell cycle progression and expression of the Pax7 regulator. |
--- |
45 |
2022 |
Distinctive Roles of YAP and TAZ in Human Endothelial Progenitor Cells Growth and Functions. |
EPCs, YAP |
46 |
2022 |
Dnah9 mutant mice and organoid models recapitulate the clinical features of patients with PCD and provide an excellent platform for drug screening. |
ODAs, PCD |
47 |
2022 |
Downregulation of CDK5 signaling in the dorsal striatum alters striatal microcircuits implicating the association of pathologies with circadian behavior in mice. |
Cdk5, CRISPR, DS, PD |
48 |
2022 |
Effects of Lipolysis-Stimulated Lipoprotein Receptor on Tight Junctions of Pancreatic Ductal Epithelial Cells in Hypertriglyceridemic Acute Pancreatitis. |
AP, HTG-AP, OE, PA, PDECs, TG, TJs, TRIC |
49 |
2022 |
Enteroviral 2B Interacts with VDAC3 to Regulate Reactive Oxygen Species Generation That Is Essential to Viral Replication. |
EV, ROS, VDAC3 |
50 |
2022 |
Epigenetic modulation enhances immunotherapy for pancreatic ductal adenocarcinoma. |
PDAC, TME |
51 |
2022 |
Expression of fatty acid synthase genes and their role in development and arboviral infection of Aedes aegypti. |
AaFAS, DENV2, FAS |
52 |
2022 |
F-Actin Dysplasia Involved in Organ of Corti Deformity in Gjb2 Knockdown Mouse Model. |
Cx26, OHCs, PCs |
53 |
2022 |
Functional characterisation of the amyotrophic lateral sclerosis risk locus GPX3/TNIP1. |
ALS, FUMA, GWAS, MO, PoPS, S-LDSC, TWAS |
54 |
2022 |
Galectin-3 administration drives remyelination after hypoxic-ischemic induced perinatal white matter injury. |
Gal-3, HI, PWMI, rGal-3 |
55 |
2022 |
GALNT12 is associated with the malignancy of glioma and promotes glioblastoma multiforme invitro by activating Akt signaling. |
CGGA, EGF, GalNAc-Ts, GBM, KO |
56 |
2022 |
Glucose-regulated protein 78 modulates cell growth, epithelial-mesenchymal transition, and oxidative stress in the hyperplastic prostate. |
BPH, EMT, GRP78, OS, qRT-PCR |
57 |
2022 |
GPCR/endocytosis/ERK signaling/S2R is involved in the regulation of the internalization, mitochondria-targeting and -activating properties of human salivary histatin 1. |
CME, F-Hst1, GPCR, Hst1, S2R, TMEM97 |
58 |
2022 |
GRK3 is a poor prognosticator and serves as a therapeutic target in advanced gastric adenocarcinoma. |
GAC, GPCR, GRK3, OE |
59 |
2022 |
HDAC5-mediated Smad7 silencing through MEF2A is critical for fibroblast activation and hypertrophic scar formation. |
HDAC, HS, MEF2A, TGF-beta |
60 |
2022 |
High expression of nectin-1 indicates a poor prognosis and promotes metastasis in hepatocellular carcinoma. |
HCC |
61 |
2022 |
Hindbrain insulin controls feeding behavior. |
DVC, RIP |
62 |
2022 |
Histone H3K36me2 demethylase KDM2A promotes bladder cancer progression through epigenetically silencing RARRES3. |
ATRA, SE |
63 |
2022 |
Histone Methyltransferase SETD2 Is Required for Porcine Early Embryonic Development. |
ICM, RNAi, SETD2, TE |
64 |
2022 |
HNF1A POU Domain Mutations Found in Japanese Liver Cancer Patients Cause Downregulation of HNF4A Promoter Activity with Possible Disruption in Transcription Networks. |
DEGs, HCC, HNF1A, ICGC, KEGG, KO, POU |
65 |
2022 |
HOXA5-Mediated Stabilization of IkappaBalpha Inhibits the NF-kappaB Pathway and Suppresses Malignant Transformation of Breast Epithelial Cells. |
DKI |
66 |
2022 |
Human Cytomegalovirus Manipulates Syntaxin 6 for Successful Trafficking and Subsequent Infection of Monocytes. |
HCMV, Stx6, TGN |
67 |
2022 |
Identification of Potential Megalin/Cubilin Substrates Using Extensive Proteomics Quantification from Kidney Megalin-Knockdown Mice. |
MWs |
68 |
2022 |
IL-10 partly mediates the ability of MSC-derived extracellular vesicles to attenuate myocardial damage in experimental metabolic renovascular hypertension. |
EVs, IL, MetS, MSCs, RVH, WT |
69 |
2022 |
IL-6/IFN-gamma double knockdown CAR-T cells reduce the release of multiple cytokines from PBMCs in vitro. |
CRS, IFN-gamma, IL-6, PBMCs |
70 |
2022 |
Increased Expression and Altered Cellular Localization of Fibroblast Growth Factor Receptor-Like 1 (FGFRL1) Are Associated with Prostate Cancer Progression. |
FGFRL1, FGFRL1, FGFRs, GSs, PCa, TMAs |
71 |
2022 |
Influenza A Virus Uses PSMA2 for Downregulation of the NRF2-Mediated Oxidative Stress Response. |
IAV, Nrf2, PSMA2, ROS |
72 |
2022 |
Insufficient HtrA2 causes meiotic defects in aging germinal vesicle oocytes. |
GV, MI, MII, OE |
73 |
2022 |
JNK initiates Beclin-1 dependent autophagic cell death against Akt activation. |
KO |
74 |
2022 |
Latent transforming growth factor β binding protein 3 controls adipogenesis. |
BMSC, GARP, LTBP, PPARgamma, TGF-beta |
75 |
2022 |
LDH-A-Modulation and the Variability of LDH Isoenzyme Profiles in Murine Gliomas: A Link with Metabolic and Growth Responses. |
--- |
76 |
2022 |
LIS1 and NDEL1 Regulate Axonal Trafficking of Mitochondria in Mature Neurons. |
DHC, DRG, OE |
77 |
2022 |
LncRNA affects epigenetic reprogramming of porcine embryo development by regulating global epigenetic modification and the downstream gene SIN3A. |
IVF |
78 |
2022 |
Long non-coding RNA Tug1 modulates mitochondrial and myogenic responses to exercise in skeletal muscle. |
lncRNA, PPARGC1A, TUG1 |
79 |
2022 |
Long non-coding RNA TUG1 sponges microRNA-9 to protect podocytes from high glucose-induced apoptosis and mitochondrial dysfunction via SIRT1 upregulation. |
HG, miR, OE, SIRT1, TUG1 |
80 |
2022 |
Loss of Mature Lamin A/C Triggers a Shift in Intracellular Metabolic Homeostasis via AMPKα Activation. |
ACC1, ADMSCs, AMPKalpha, FPLD, FTI, HCC, KO |
81 |
2022 |
Loss of tetraspanin-7 expression reduces pancreatic β-cell exocytosis Ca2+ sensitivity but has limited effect on systemic metabolism. |
Tspan7 |
82 |
2022 |
LYAR Promotes Colorectal Cancer Progression by Upregulating FSCN1 Expression and Fatty Acid Metabolism. |
ChIP, CRC, Fascin-1 |
83 |
2022 |
MALAT1 promotes platelet activity and thrombus formation through PI3k/Akt/GSK-3beta signalling pathway. |
--- |
84 |
2022 |
Maternal Factor Dppa3 Activates 2C-Like Genes and Depresses DNA Methylation in Mouse Embryonic Stem Cells. |
DMRs, ESCs, OE, ZGA |
85 |
2022 |
MC4R Deficiency Causes Dysregulation of Postsynaptic Excitatory Synaptic Transmission as a Crucial Culprit for Obesity. |
AMPAR, MC4R, PKA, PVH |
86 |
2022 |
MCU controls melanoma progression through a redox-controlled phenotype switch. |
--- |
87 |
2022 |
Mechanistic and Clinical Evidence Supports a Key Role for Cell Division Cycle Associated 5 (CDCA5) as an Independent Predictor of Outcome in Invasive Breast Cancer. |
BC, CDCA5, HR, LVI, PI3K |
88 |
2022 |
MEN1 silencing triggers the dysregulation of mTORC1 and MYC pathways in ER+ breast cancer cells. |
BC |
89 |
2022 |
Metabolic Reprogramming in Response to Alterations of Mitochondrial DNA and Mitochondrial Dysfunction in Gastric Adenocarcinoma. |
ECAR, GAC, HKII, mtDNA, NC-GM, NGM, NT, OCR, P-PDH, PT |
90 |
2022 |
Metabolic requirement for GOT2 in pancreatic cancer depends on environmental context. |
alpha-KG, CAFs, CM, GOT2, PDA, TME |
91 |
2022 |
Metalloprotease ADAM9 cleaves ephrin-B ligands and differentially regulates Wnt and mTOR signaling downstream of Akt kinase in colorectal cancer cells. |
CRC |
92 |
2022 |
Miltefosine as a PPM1A activator improves AD-like pathology in mice by alleviating tauopathy via microglia/neurons crosstalk. |
AAV, AD, CX3CR1, NF-kappaB, NLRP3, OE, PPM1A |
93 |
2022 |
miRNA-223-3p regulates ECT2 to promote proliferation, invasion, and metastasis of gastric cancer through the Wnt/beta-catenin signaling pathway. |
ECT2, GC, miR-223-3p, miRNAs, OE |
94 |
2022 |
Mitochondrial ATP synthase c-subunit leak channel triggers cell death upon loss of its F1 subcomplex. |
ACLC, MPT |
95 |
2022 |
Mitochondrial Respiration-Dependent ANT2-UCP2 Interaction. |
ANTs, CATR, HEK293A, UCPs |
96 |
2022 |
Multifunctional regulation of VAMP3 in exocytic and endocytic pathways of RBL-2H3 cells. |
Ags, MCs, NT, SNAREs, VAMP3 |
97 |
2022 |
Mycobacterium tuberculosis ketol-acid reductoisomerase down-regulation affects its ability to persist, and its survival in macrophages and in mice. |
BCAAs, CFU, Mtb, WT |
98 |
2022 |
Nascent polypeptide-Associated Complex and Signal Recognition Particle have cardiac-specific roles in heart development and remodeling. |
CHD, NAC, SRP |
99 |
2022 |
NAT10 Maintains OGA mRNA Stability Through ac4C Modification in Regulating Oocyte Maturation. |
NAT10, O-GlcNAc, OGA |
100 |
2022 |
Nestin Modulates Airway Smooth Muscle Cell Migration by Affecting Spatial Rearrangement of Vimentin Network and Focal Adhesion Assembly. |
Plk1 |
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