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Abbreviation : L-ASP
Long Form : L-asparaginase
No. Year Title Co-occurring Abbreviation
2022 Amino acid stress response genes promote L-asparaginase resistance in pediatric acute lymphoblastic leukemia. ALL, ASNS, ATF4, ChIP-seq
2022 Antagonizing Glutamine Bioavailability Promotes Radiation Sensitivity in Prostate Cancer. PCa
2022 Comparative Effectiveness of Peg-Asparaginase and L-Asparaginase on Coagulation Markers Among Pediatric Patients with Acute Lymphoblastic Leukemia. ALL, ASP, ATIII, PEG-ASP, Pr-S, PrC, PT, PTT
2022 Neurotoxicity Associated with Treatment of Acute Lymphoblastic Leukemia Chemotherapy and Immunotherapy. ALL, CNS, ICANS, MTX, VCR
2021 Acute pancreatitis in children with acute lymphoblastic leukemia correlates with L-asparaginase dose intensity. AAP, ALL
2021 The Clinical Features and Survival Outcome of 107 Newly Diagnosed Advanced Stage Extranodal NK/T-Cell Lymphoma Cases: A Triple-Center Study. ENKTL, GELOXD, OS, PFS, PINK
2020 Allergic reactions to asparaginase: retrospective cohort study in pediatric patients with acute lymphoid leukemia. ASP, IM
2020 Antiproliferative effects of L-asparaginase in acute myeloid leukemia. AML, MIT
2020 Concurrent use of rabacfosadine and L-asparaginase for relapsed or refractory multicentric lymphoma in dogs. CR, MPFS, ORR, RAB
10  2020 Correlation of L-asp Activity, Anti-L-asp Antibody, Asn and Gln With Adverse Events Especially Anaphylaxis Risks in PEG-asp-Contained Regime Treated Pediatric ALL Patients. AEs, ALL, PEG-asp
11  2020 National Italian Delphi panel consensus: which measures are indicated to minimize pegylated-asparaginase associated toxicity during treatment of adult acute lymphoblastic leukemia? ALL, PEG-Asp
12  2020 Thromboembolism prophylaxis during L-asparaginase therapy in acute lymphoblastic leukemia - time to reconsider current approaches? ALL, LMWH, VTE
13  2020 Thromboembolism prophylaxis in adult patients with acute lymphoblastic leukemia treated in the GRAALL-2005 study. ALL, AT, VTE
14  2020 [State-of-the-art therapy for adult Philadelphia chromosome-negative acute lymphoblastic leukemia]. ALL, allo-HSCT, MRD
15  2019 Discontinuation of L-asparaginase and poor response to prednisolone are associated with poor outcome of ETV6-RUNX1-positive pediatric B-cell precursor acute lymphoblastic leukemia. B-ALL, EFS, JACLS, OS
16  2019 Disordered hemostasis associated with severely depressed fibrinolysis demonstrated using a simultaneous thrombin and plasmin generation assay during L-asparaginase induction therapy in pediatric acute lymphoblastic leukemia. ALL, BFM, P-Peak, T-EP
17  2019 Dynamic changes in specific anti-L-asparaginase antibodies generation during acute lymphoblastic leukemia treatment. ---
18  2019 Evaluation of Insulin-mediated Regulation of AKT Signaling in Childhood Acute Lymphoblastic Leukemia. ALL, DNR, IGF-1R, VCR
19  2019 EVI1 triggers metabolic reprogramming associated with leukemogenesis and increases sensitivity to L-asparaginase. ASNS, EVI1, OXPHOS
20  2019 Gene expression of ASNS, LGMN and CTSB is elevated in a subgroup of childhood BCP-ALL with PAX5 deletion. ASNS, BCP-ALL, CTSB, LGMN, PAX5, RFS
21  2018 Hydrolytically Degradable PEGylated Polyelectrolyte Nanocomplexes for Protein Delivery. ELISA, GPC, PEG
22  2018 Identification of a cytogenetic and molecular subgroup of acute myeloid leukemias showing sensitivity to L-Asparaginase. ALL, AMLs, ASNS, t-MN
23  2018 PEG-L-CHOP treatment is safe and effective in adult extranodal NK/T-cell lymphoma with a low rate of clinical hypersensitivity. NK, OS, PEG-ASP
24  2018 Plasma ammonia concentration after L-asparaginase therapy in 27 dogs with high-grade lymphoma or leukemia. ---
25  2018 Retrospective analysis of doxorubicin and prednisone as first-line therapy for canine B-cell lymphoma. DOX, OS, PFS
26  2018 Selection and Evaluation of Appropriate Reference Genes for RT-qPCR Normalization of Volvariella volvacea Gene Expression under Different Conditions. ACTB, CyP, MSF1, SPRYp, TUBalpha, V. volvacea
27  2018 [Analysis of Factors Influencing Prognosis of 87 Adults with Ph Chromosome Negative ALL]. ALL, allo-HSCT, CR, DFS, OS, Ph
28  2018 [Recurrent thrombosed external hemorrhoids due to L-asparaginase administration in a Philadelphia chromosome-positive acute lymphoblastic leukemia patient]. TEH
29  2017 Comparison of Native Escherichia coli L-Asparaginase versus Pegylated Asparaginase, in Combination with Ifosfamide, Methotrexate, Etoposide, and Prednisolone, in Extranodal NK/T-Cell Lymphoma, Nasal Type. IMEP, NK, PEG-ASP
30  2017 Incidence of asparaginase-related hepatotoxicity, pancreatitis, and thrombotic events in adults with acute lymphoblastic leukemia treated with a pediatric-inspired regimen. ALL, PEG
31  2017 PEG-asparaginase in BFM-90 regimen improves outcomes in adults with newly diagnosed lymphoblastic lymphoma. ALL, LBL, PEG-ASP, PEG-ASP-BFM-90
32  2017 Venous thromboembolism following L-asparaginase treatment for lymphoid malignancies in Korea. ALL, VTE
33  2016 Application of Glutamine-enriched nutrition therapy in childhood acute lymphoblastic leukemia. ALL, Gln, NK, PA, RBP
34  2016 Endoscopic ultrasound-guided cystogastrostomy for successful drainage of pancreatic pseudocyst: a pediatric case report. ALL, EUS
35  2016 Iatrogenic Coagulopathy and the Development of Posterior Reversible Encephalopathy Syndrome after L-asparaginase Chemotherapy. ATIII, PRES
36  2016 L-asparaginase-induced abnormality in plasma glucose level in patients of acute lymphoblastic leukemia admitted to a tertiary care hospital of Odisha. ALL
37  2016 TFDP3 confers chemoresistance in minimal residual disease within childhood T-cell acute lymphoblastic leukemia. DEX, DNR, MRD, T-ALL, VCR
38  2016 [Comparison of the Effectiveness and Safety of Combined Chemotherapy with PEG-Asp for Treatment of ALL and T-NHL Patients]. ALL, PEG-Asp, T-NHL
39  2016 [Retrospective analyses of CHOPE plus L-asparaginase regimen in treatment of T-cell lymphoma]. ENKTCL, T-NHL
40  2015 Catalytic Role of the Substrate Defines Specificity of Therapeutic l-Asparaginase. Asn
41  2015 Clinical analysis and prognostic significance of L-asparaginase containing multidrug chemotherapy regimen in incipient peripheral T-cell lymphoma. CR, IPI, L-ASP group, OR, OS, PFS, PR, PTCL
42  2015 Effects of Prednisolone, L-Asparaginase, Gemfibrozil, and Combinations of These Elements on Mice Lipid Profile, Liver, and Pancreas. COL, CSs, HDL, LDL
43  2015 L-Asparaginase monotherapy for EBV-positive T/NK lymphoproliferative diseases: A pilot Study. EBV
44  2015 Meta-analysis and meta-regression analysis to compare the outcomes of chemotherapy for T- and B-lineage acute lymphoblastic leukemia (ALL): the use of dexamethasone, L-asparaginase, and/or methotrexate may improve the outcome of T-lineage ALL. ALL, DEX, MTX
45  2015 Reconstitution of L-Asparaginase in Siliconized Syringes with Shaking and Headspace Air Induces Protein Aggregation. ---
46  2015 [A clinical observation of treatment of peripheral T-cell lymphoma with L-asparaginase-containing combination chemotherapy]. CR, OR, OS, PFS, PR
47  2015 [Non-upper aerodigestive tract NK/T- cell lymphoma: an analysis of clinical features and survival from a single center in China]. NUAT-NKTCL, OS
48  2014 A phase II clinical trial of polyethylene glycol-conjugated L-asparaginase in patients with advanced ovarian cancer: Early closure for safety. ---
49  2014 Asparagine synthetase expression and its potential prognostic value in patients with NK/T cell lymphoma. ASNS, bDNA-LCT, NK
50  2014 Early diagnosis of asparaginase-associated pancreatitis based on elevated serum elastase-1 levels: Case reports. AAP, ALL
51  2014 Efficacy and tolerance of pegaspargase-based chemotherapy in patients with nasal-type extranodal NK/T-cell lymphoma: a pilot study. APTT, CR, NK, ORR, PEG-Asp
52  2014 Efficacy of gemcitabine combined with oxaliplatin, L-asparaginase and dexamethasone in patients with newly-diagnosed extranodal NK/T-cell lymphoma. DXM, GEM, NK, OS, PFS
53  2014 Ifosfamide, methotrexate, etoposide, and prednisolone (IMEP) plus L-asparaginase as a first-line therapy improves outcomes in stage III/IV NK/T cell-lymphoma, nasal type (NTCL). CI, HR, IMEP, IMEP, NTCL, NTCL, OS, PFS
54  2014 L-asparaginase induced hypoglycemia in a case of acute lymphoblastic leukemia: a patient report. ALL
55  2014 L-asparaginase-induced severe acute pancreatitis in an adult with extranodal natural killer/T-cell lymphoma, nasal type: A case report and review of the literature. ENKTL, HBV
56  2014 Relationship between modified CT severity index and clinical features of L-asparaginase-associated pancreatitis in pediatric acute lymphoblastic leukemia. AST, BUN, CRP, L-AP, LDH, MCSI, TPN
57  2014 Targeted metabolomic analysis of amino acid response to L-asparaginase in adherent cells. ---
58  2014 The glutaminase activity of L-asparaginase is not required for anticancer activity against ASNS-negative cells. ASNS
59  2014 [Advances of treatment for nature killer/T-cell lymphoma]. EBV, NKTCL
60  2014 [Advances on the role of pegaspargase in the treatment of childhood leukemia]. PEG-ASP
61  2014 [Efficacy of chemotherapy combined with bortezomib for two cases of relapsed/refractory acute lymphoblastic leukemia]. ALL, BZM
62  2013 Chemotherapy induces enhanced procoagulant activity through phosphatidylserine exposure in acute lymphoblastic leukemia. ALL, DNR, MNCs, PCA, PS
63  2013 Delayed-type hypersensitivity in response to L-asparaginase in a case of acute lymphoblastic leukemia. ---
64  2013 Expression of asparagine synthetase predicts in vitro response to L-asparaginase in canine lymphoid cell lines. ASNS
65  2013 Monitoring of anti-L-asparaginase antibody and L-asparaginase activity levels in a pediatric patient with acute lymphoblastic leukemia and hypersensitivity to native Escherichia coli L-asparaginase during desensitization courses. ---
66  2013 The evaluation of protein Z levels of children with acute lymphoblastic leukaemia during induction therapy. ALL
67  2013 [Analysis of L-asparaginase induced elevation of blood ammonia and hepatic encephalopathy]. ---
68  2013 [Update on L-asparaginase treatment in paediatrics]. ---
69  2012 Acute hyperammonemia after L-asparaginase administration in a dog. ---
70  2012 Asparagine and aspartic acid concentrations in bone marrow versus peripheral blood during Berlin-Frankfurt-Munster-based induction therapy for childhood acute lymphoblastic leukemia. ALL, BFM, BM, PB
71  2012 Conservative management of L-asparaginase-induced hypertriglyceridemia in an adult patient: a case report and review of the literature. ---
72  2012 Hypoglycemia associated with L-asparaginase in acute lymphoblastic leukemia treatment: a case report. ---
73  2012 L-asparaginase inhibits invasive and angiogenic activity and induces autophagy in ovarian cancer. HMVEC
74  2012 Low expression of asparagine synthetase in lymphoid blasts precludes its role in sensitivity to L-asparaginase. ALL, ASNS
75  2012 The coagulopathy and thrombotic risk associated with L-asparaginase treatment in adults with acute lymphoblastic leukaemia. ALL, AT
76  2012 [Allergic complications of L-asparaginase therapy in children with acute lymphoblastic leukaemia]. ALL
77  2012 [Fulminant hepatitis possibly caused by L-asparaginase during induction chemotherapy in a patient with acute lymphoblastic leukemia]. ALL
78  2011 Curcumin potentiates antitumor activity of L-asparaginase via inhibition of the AKT signaling pathway in acute lymphoblastic leukemia. ALL
79  2011 Epileptic seizures after octreotide administration in a 6.5-year-old female with ALL and L-asparaginase associated pancreatitis: a possible drug interaction. ALL
80  2009 Acute pancreatitis in children with acute lymphoblastic leukemia after chemotherapy. ALL, AP
81  2009 Acute pancreatitis in children with acute lymphoblastic leukemia treated with L-asparaginase. ALL, AP, CT
82  2009 Asparagine synthetase: a new potential biomarker in ovarian cancer. ASNS
83  2009 Dexamethasone induces a heat-stress response that ameliorates the conformational consequences on antithrombin of L-asparaginase treatment. ER, HSR, UPR
84  2009 Effect of L-asparaginase combined with vincristine and prednisolone on acute myeloblastic leukemia (M0) associated with non-Hodgkin lymphoma. AML, AS, CR, NHL
85  2009 Increased levels of tissue factor activity and procoagulant phospholipids during treatment of children with acute lymphoblastic leukaemia. ADR, ALL, FRALLE, GC, PCA, PPL, TFa, VCR
86  2009 [Side effects of L-asparaginase during therapies for remission induction and maintenance in children with acute lymphocytic leukemia]. ALL
87  2008 Asparagine synthetase is a predictive biomarker of L-asparaginase activity in ovarian cancer cell lines. ASNS
88  2008 Downregulation of Notch signaling by gamma-secretase inhibition can abrogate chemotherapy-induced apoptosis in T-ALL cell lines. DEX, GSIs, T-ALL
89  2008 Long-term outcome of L86 and L97 protocols for adult acute lymphoblastic leukemia. ALL, CR, DFS, OS, Ph, PSL, VCR
90  2008 Purification of Escherichia coli L-asparaginase mutants by a native polyacrylamide gel electrophoresis. ---
91  2007 Enhanced secretion of adhesive recognition sequence containing hirudin III mutein in E. coli. ---
92  2007 Genetic alterations determine chemotherapy resistance in childhood T-ALL: modelling in stage-specific cell lines and correlation with diagnostic patient samples. ABCB1, ASNS, ASS1, DNR, PRED, T-ALL, VCR
93  2007 [Superior sagittal sinus thrombosis during remission induction therapy for acute lymphoblastic leukemia]. ALL, SSST
94  2006 Probing the antigenicity of E. coli L-asparaginase by mutational analysis. ---
95  2006 Up-regulation of asparagine synthetase expression is not linked to the clinical response L-asparaginase in pediatric acute lymphoblastic leukemia. ALL, AS, PEG-Asp
96  2006 [Otoacoustic emissions measurements in children during the chemotherapy because of the acute lymphoblastic leukemia]. 6-MP, ALL, CPM, DNR, DOX, DPOAEs, MTX, OAEs, VCR
97  2006 [Preliminary study on the safety and pharmacodynamic action of low dose L-asparaginase]. ALL, RP-HPLC
98  2006 [Reversible posterior leukoencephalopathy syndrome probably caused by L-asparaginase]. CT, FLAIR, MRI, RPLS
99  2005 Does L-asparaginase influence efficacy or toxicity when added to a standard CHOP protocol for dogs with lymphoma? ---
100  2005 [Temporary effective treatment with L-asparaginase for a patient with refractory nasal NK/T-cell lymphoma]. ---