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Abbreviation : LOAEL
Long Form : lowest observed adverse effect level
No. Year Title Co-occurring Abbreviation
2022 In silico Modeling and Toxicity Profiling of a Set of Quinoline Derivatives as c-MET Inhibitors in the treatment of Human Tumors. ---
2021 14-Day Nose-Only Inhalation Toxicity and Haber's Rule Study of NNK in Sprague-Dawley Rats. BW, NNAL
2021 90-day nose-only inhalation toxicity study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Sprague-Dawley rats. BW, MN, NNAL, NOAEL
2021 A toxicological evaluation of geranylgeraniol. ---
2021 Acrylamide induces a thyroid allostasis-adaptive response in prepubertal exposed rats. AA, EDCs, HPT, TH
2021 Chronic Reproductive Toxicity Thresholds for Northern Bobwhite Quail (Colinus virginianus) Exposed to Perfluorohexanoic Acid (PFHxA) and a Mixture of Perfluorooctane Sulfonic Acid (PFOS) and PFHxA. CTV, PFAS, PFHxA, PFOS
2021 Comparative influences of dermal and inhalational routes of exposure on hazards of cleaning product ingredients among mammalian model organisms. CPISI, CTDs, NOAEL, TCs, TTCs, UFs
2021 Comprehensive Virtual Screening of the Antiviral Potentialities of Marine Polycyclic Guanidine Alkaloids against SARS-CoV-2 (COVID-19). ADMET, BBB, MD, Mpro
2021 Constructing a developmental and reproductive toxicity database of chemicals (DART NIHS DB) for integrated approaches to testing and assessment. AOPs, DART, DART NIHS DB, DBs, RDT
10  2021 Effects of a Low Dose of T-2 Toxin on the Percentage of T and B Lymphocytes and Cytokine Secretion in the Porcine Ileal Wall. GALT
11  2021 Estimation of Benchmark Dose of Cumulative Cadmium Exposure for Renal Tubular Effect. BMDL, BMR, Cd-A
12  2021 Issues in the design, analysis, and application of rodent developmental neurotoxicology studies. DNT, EPA, FOB
13  2021 Levels of bioavailable manganese in river sediment may elevate reproductive risk in model organism Caenorhabditis elegans. ER, RQs
14  2021 Looking for the LOAEL or NOAEL Concentration of Nickel-Oxide Nanoparticles in a Long-Term Inhalation Exposure of Rats. ---
15  2021 Oral Subacute Exposure to Cadmium LOAEL Dose Induces Insulin Resistance and Impairment of the Hormonal and Metabolic Liver-Adipose Axis in Wistar Rats. ---
16  2021 Phytol, not propylene glycol, causes severe pulmonary injury after inhalation dosing in Sprague-Dawley rats. ---
17  2021 Risk factors and assessment strategies for the evaluation of human or environmental risk from metal(loid)s - A focus on Ireland. DDI
18  2021 Safety Evaluation for Restorin NMN, a NAD+ Precursor. NMN, NOAEL
19  2021 Species- and Tissue-Specific Chronic Toxicity Values for Northern Bobwhite Quail (Colinus virginianus) Exposed to Perfluorohexane Sulfonic Acid and a Binary Mixture of Perfluorooctane Sulfonic Acid and Perfluorohexane Sulfonic Acid. CTVs, ERAs, NOAEL, PFAS, PFHxA, PFHxS, PFOS, TRVs
20  2021 The Production of Testosterone and Gene Expression in Neonatal Testes of Rats Exposed to Diisoheptyl Phthalate During Pregnancy is Inhibited. DIHP, GD, INSL3
21  2021 Tolerable amounts of amino acids for human supplementation: summary and lessons from published peer-reviewed studies. NOAEL, RQ, UC, UL
22  2021 Toxic effects of atrazine on immune function in BALB/c mice. AST, ATZ, BUN, CHO, DTH, IgG, IL-5, LYM, MON, NEUT, PFC, WBC
23  2021 Toxicity of sodium nitrite-based vertebrate pesticides for European starlings (Sturnus vulgaris). SN
24  2021 Update of the risk assessment of hexabromocyclododecanes (HBCDDs) in food. BW, HBCDDs, HBGV, MOE
25  2021 Update on the Health Effects of Bisphenol A: Overwhelming Evidence of Harm. BPA, FDA
26  2021 Variability in in vivo studies: Defining the upper limit of performance for predictions of systemic effect levels. ACM, LEL, MLR, MSE, NAMs, RMSE, ToxRefDB
27  2020 Bisphenol A exposure is involved in the development of Parkinson like disease in Drosophila melanogaster. BPA
28  2020 Cardiotoxicity and Cardioprotection by Artesunate in Larval Zebrafish. ART, fzd7a
29  2020 Comment on Lachenmeier et al (2020) "Are side effects of cannabidiol (CBD) products caused by tetrahydrocannabinol (THC) contamination?": disputation on various points in the publication. CBD, THC, THCA
30  2020 Effect of short-chain chlorinated paraffins on metabolic profiling of male SD rats. PUFAs, SCCPs
31  2020 Evaluation of neurobehavioral abnormalities and immunotoxicity in response to oral imidacloprid exposure in domestic chickens (Gallus gallus domesticus). ---
32  2020 Examining the evidence of non-monotonic dose-response in Androgen Receptor agonism high-throughput screening assay. AR, HTS, NMDR, NOAEL
33  2020 Exposure to lead, mercury, styrene, and toluene and hearing impairment: evaluation of dose-response relationships, regulations, and controls. ---
34  2020 Fosfomycin (Veterinary Medicinal Products): Summary. BW, FSCJ
35  2020 Gestational Exposure to Bisphenol A Affects Testicular Morphology, Germ Cell Associations, and Functions of Spermatogonial Stem Cells in Male Offspring. BPA, BW, NOAEL, TDI
36  2020 Initial hazard assessment of 1,4-dichlorobutane: Genotoxicity tests, 28-day repeated-dose toxicity test, and reproductive/developmental toxicity screening test in rats. 1,4-DCB
37  2020 Lowest observed adverse effect level of pulmonary pathological alterations due to nitrous acid exposure in guinea pigs. Lm, ppm, SEM, TEM
38  2020 Metabolic Consequences of Supplemented Methionine in a Clinical Context. Hcy, HHcy, Met
39  2020 Paternal Exposure to Bisphenol-A Transgenerationally Impairs Testis Morphology, Germ Cell Associations, and Stemness Properties of Mouse Spermatogonial Stem Cells. BPA, SSCs
40  2020 Safety and efficacy of astaxanthin-dimethyldisuccinate (Carophyll Stay-Pink 10%-CWS) for salmonids, crustaceans and other fish. ADI, ATX-DMDS, BW
41  2020 Safety assessment of a fenugreek dietary fiber-based formulation of capsaicinoids-rich red chili (Capsicum annum) extract (Capsifen): Acute and sub-chronic studies. ---
42  2020 Scientific opinion on the safety of selenite triglycerides as a source of selenium added for nutritional purposes to food supplements. BW, NDA, NF
43  2020 Species- and Tissue-Specific Avian Chronic Toxicity Values for Perfluorooctane Sulfonate (PFOS) and a Binary Mixture of PFOS and Perfluorohexane Sulfonate. CTVs, PFAS, PFHxS, PFOS, TRVs
44  2020 Trifluoroiodomethane (CF3I) (2019). NOAEL, POD, WEEL
45  2019 Acute and sub-chronic oral toxicity studies of hesperidin isolated from orange peel extract in Sprague Dawley rats. AOT
46  2019 Acute and Subacute Toxicity Assessment of Oxyclozanide in Wistar Rats. BW
47  2019 Analysis of individual and combined estrogenic effects of bisphenol, nonylphenol and diethylstilbestrol in immature rats with mathematical models. BMD, BPA, CA, DES, EDCs, NP
48  2019 Cis-1,1,1,4,4,4-hexafluoro-2-butene (HFO-1336mzz-Z) (2018). NOAEL, OECD, SD, TWA, WEEL
49  2019 Critical review and probabilistic health hazard assessment of cleaning product ingredients in all-purpose cleaners, dish care products, and laundry care products. APC, CTDs, DCP, LCP, NOAEL, TCs, TTCs, UF
50  2019 Juvenile Toxicity Rodent Model to Study Toxicological Effects of Bisphenol A (BPA) at Dose Levels Derived From Italian Children Biomonitoring Study. BMD, BPA, NOAEL
51  2019 Potential toxicity effects of Anastatica hierochuntica aqueous extract on prenatal development of Sprague-Dawley rats. A. hierochuntica, AHAE, GD, NMDRC, NOAEL
52  2019 Quantitative prediction of repeat dose toxicity values using GenRA. GenRA, POD, ToxRefDB
53  2019 Use of a Mouse Model of Experimentally Induced Endometriosis to Evaluate and Compare the Effects of Bisphenol A and Bisphenol AF Exposure. BPA, BPAF, NOAEL
54  2019 Use of toxicant sensitivity distributions (TSD) for development of exposure guidelines for risk to human health from benzene. ADD, CP, CPD, GVs, LADD, LTE, TSD
55  2019 [Subchronic toxicity test of songaria cynomorium herb aqueous extract in rat]. NOAEL, PT
56  2018 28-Day Oral Chronic Toxicity Study of Arctigenin in Rats. CREA, NOAEL
57  2018 A systematic review of experimental animal studies on microbial bioaerosols: Dose-response data for the derivation of exposure limits. NOAEL
58  2018 Benchmark dose analysis of multiple thyroid toxicity endpoints in ovariectomized rats exposed to propylthiouracil. 5'-DI, BMD, ME, POD, PTU
59  2018 Dose-Response Modelling of Paralytic Shellfish Poisoning (PSP) in Humans. PSP, PSTs, STX
60  2018 Ergot Alkaloids at Doses Close to EU Regulatory Limits Induce Alterations of the Liver and Intestine. BMDL, BW, EAs, EFSA
61  2018 Experiencing a probabilistic approach to clarify and disclose uncertainties when setting occupational exposure limits. AFs, NOAEL, OELs
62  2018 Hormesis of methylmercury-human serum albumin conjugate on N9 microglia via ERK/MAPKs and STAT3 signaling pathways. CNS, HSA, MeHg-HSA
63  2018 Identification of novel uncertainty factors and thresholds of toxicological concern for health hazard and risk assessment: Application to cleaning product ingredients. NOAEL, TTC, UFs
64  2018 In utero combined di-(2-ethylhexyl) phthalate and diethyl phthalate exposure cumulatively impairs rat fetal Leydig cell development. DEHP, DEP
65  2018 Initial hazard assessment of benzyl salicylate: In vitro genotoxicity test and combined repeated-dose and reproductive/developmental toxicity screening test in rats. ---
66  2018 Long-Term Effects of Unmodified 50nm ZnO in Mice. nano-ZnO
67  2018 Mixed "Antiandrogenic" Chemicals at Low Individual Doses Produce Reproductive Tract Malformations in the Male Rat. ---
68  2018 Review of animal studies on the cardiovascular effects of caffeine. HED
69  2018 Submarine exposure guideline recommendations for carbon dioxide based on the prenatal developmental effects of exposure in rats. CEL, EEL
70  2018 Telomerase gene expression bioassays indicate metabolic activation of genotoxic lower chlorinated polychlorinated biphenyls. PCBs, ROS
71  2018 The NOAEL Metformin Dose Is Ineffective against Metabolic Disruption Induced by Chronic Cadmium Exposure in Wistar Rats. Cd, NOAEL
72  2017 A 90-day subchronic gavage toxicity study in Fischer 344 rats with 3-methylfuran. ---
73  2017 Developmental toxicity assessment of common excipients using a stem cell-based invitro morphogenesis model. EBs
74  2017 Effects of Oxalic Acid on Apis mellifera (Hymenoptera: Apidae). ---
75  2017 Fenquinotrione (Pesticides). 4-HPDDase, ADI, ARfD, FSCJ, NOAEL
76  2017 Health effects following subacute exposure to geogenic dust collected from active drainage surfaces (Nellis Dunes Recreation Area, Las Vegas, NV). NDRA, ORV
77  2017 Health effects from exposure to atmospheric mineral dust near Las Vegas, NV, USA. NDRA, ORV
78  2017 Investigations on the dose-response relationship of combined exposure to low doses of three anti-androgens in Wistar rats. ---
79  2017 Melengestrol Acetate (Veterinary Medicinal Products). ADI, FSCJ, NOAEL
80  2017 Oral subchronic exposure to silver nanoparticles causes renal damage through apoptotic impairment and necrotic cell death. TEM
81  2017 Predicting reactivity threshold in children with anaphylaxis to peanut. BAT, CAPT, DBPCFC, OFC, sIgE, SPT
82  2017 Tolerance to increased supplemented dietary intakes of methionine in healthy older adults. Met, NOAEL
83  2017 Toxicity Studies of Ethyl Maltol and Iron Complexes in Mice. BW, KM
84  2016 BASALIT trial: double-blind placebo-controlled allergen immunotherapy with rBet v 1-FV in birch-related soya allergy. AIT, DBPCFC, FV, objS, PPP
85  2016 Developmental toxicity of N-methylaniline following prenatal oral administration in rats. BW, NMA, NOAEL
86  2016 Estimating the Potential Toxicity of Chemicals Associated with Hydraulic Fracturing Operations Using Quantitative Structure-Activity Relationship Modeling. EPA, IRIS, QSAR
87  2016 Four-Week Repeated Intravenous Dose Toxicity and Toxicokinetic Study of TS-DP2, a Novel Human Granulocyte Colony Stimulating Factor in Rats. rhG-CSF, SD
88  2016 In Silico Models for Repeated-Dose Toxicity (RDT): Prediction of the No Observed Adverse Effect Level (NOAEL) and Lowest Observed Adverse Effect Level (LOAEL) for Drugs. MRSD, RDT
89  2016 Long-term effects of in utero and lactational exposure to butyl paraben in female rats. BP, GD
90  2016 Numeric Estimates of Teratogenic Severity from Embryo-Fetal Developmental Toxicity Studies. EFD
91  2016 Point of departure (PoD) selection for the derivation of acceptable daily exposures (ADEs) for active pharmaceutical ingredients (APIs). ADE, ADEs, APIs, BMD, NOAEL, POD
92  2016 Prepubertal exposure to an oestrogenic mycotoxin zearalenone induces central precocious puberty in immature female rats through the mechanism of premature activation of hypothalamic kisspeptin-GPR54 signaling. BW, GnRH, GPR54, ZEA
93  2016 Targeted metabolomics of Gammarus pulex following controlled exposures to selected pharmaceuticals in water. LC-HRMS, NOAEL, PPCPs
94  2016 The Monte Carlo technique as a tool to predict LOAEL. QSARs, SMILES
95  2016 Toxic effects, metabolism, and carry-over of ergot alkaloids in laying hens, with a special focus on changes of the alkaloid isomeric ratio in feed caused by hydrothermal treatment. EA
96  2016 Zebrafish embryo toxicity of anaerobic biotransformation products from the insensitive munitions compound 2,4-dinitroanisole. bio, DAAN, DNAN, MENA
97  2015 A 4-week toxicity study of methionine in male rats. NOAEL
98  2015 Acute beta-N-Methylamino-L-alanine Toxicity in a Mouse Model. BMAA
99  2015 Assessing dose-response relationships for endocrine disrupting chemicals (EDCs): a focus on non-monotonicity. EDCs, NMDR
100  2015 Assessment of learning, memory, and attention in developmental neurotoxicity regulatory studies: synthesis, commentary, and recommendations. DNT, EPA, FOB