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Abbreviation : NAC
Long Form : N-acetylcysteine
No. Year Title Co-occurring Abbreviation
2022 Comparing N-acetylcysteine and 4-methylpyrazole as antidotes for acetaminophen overdose. JNK
2022 Hypoxia-induced Maspin Expression Affects the Prognosis of Ovarian Clear Cell Carcinoma. OCCC
2022 N-Acetyl-Cysteine-Loaded Biomimetic Nanofibrous Scaffold for Osteogenesis of Induced-Pluripotent-Stem-Cell-Derived Mesenchymal Stem Cells and Bone Regeneration. iPSC-MSCs
2022 N-acetyl-L-cysteine potentially inhibits complement activation in transplantation-associated thrombotic microangiopathy. TA-TMA, WGS
2022 The effect of per os colchicine administration in combination with fenofibrate and N-acetylcysteine on triglyceride levels and the development of atherosclerotic lesions in cholesterol-fed rabbits. ELISA, IL-6, LDL
2022 Upregulation of Striatal Metabotropic Glutamate Receptor Subtype 1 (mGluR1) in Rats with Excessive Glutamate Release Induced by N-Acetylcysteine. BPND, Glu, mGluR1
2022 WAY-100635 Alleviates Corneal Lesions Through 5-HT1A Receptor-ROS-Autophagy Axis in Dry Eye. ATG5, CXCL10, DED, IL-6, ROS, TNF-alpha
2021 (-)-Epigallocatechin-3-gallate induces apoptosis and differentiation in leukaemia by targeting reactive oxygen species and PIN1. AML, APL, ATRA, EGCG, PIN1, PML, ROS
2021 2,2',4,4'-Tetrabromodiphenyl ether (BDE-47) activates Aryl hydrocarbon receptor (AhR) mediated ROS and NLRP3 inflammasome/p38 MAPK pathway inducing necrosis in cochlear hair cells. AhR, ROS
10  2021 2,5-dimethyl celecoxib induces apoptosis and autophagy via activation of ROS/JNK axis in nasopharyngeal carcinoma cells. DMC, JNK, ROS
11  2021 25-Hydroxycholesterol 3-Sulfate Recovers Acetaminophen Induced Acute Liver Injury via Stabilizing Mitochondria in Mouse Models. 25HC3S, ALF, MDA, PG, ROS
12  2021 6,8-Diprenylorobol induces apoptosis in human colon cancer cells via activation of intracellular reactive oxygen species and p53. MAPKs, ROS
13  2021 A case of trichotillomania with binge eating disorder: combined with N-acetylcysteine synergistic therapy. BED, CBT, OCRDs, TTM
14  2021 A Combined Model of Human iPSC-Derived Liver Organoids and Hepatocytes Reveals Ferroptosis in DGUOK Mutant mtDNA Depletion Syndrome. iHep-Orgs, iPSCs, MDS, NCOA4
15  2021 A conservative treatment for chronic obstructive sialoadenitis by intraductal instillation of mucolytic, steroids and antibiotic solution. ---
16  2021 A Meta-Analysis of the Efficacy of L-Carnitine/L-Acetyl-Carnitine or N-Acetyl-Cysteine in Men With Idiopathic Asthenozoospermia. LC/LAC
17  2021 A metabolomic analysis of thiol response for standard and modified N-acetyl cysteine treatment regimens in patients with acetaminophen overdose. ALI
18  2021 A new perspective on calmodulin-regulated calcium and ROS homeostasis upon carbon black nanoparticle exposure. CaM, CBNP, ROS
19  2021 A Novel Biological Activity of the STAT3 Inhibitor Stattic in Inhibiting Glutathione Reductase and Suppressing the Tumorigenicity of Human Cervical Cancer Cells via a ROS-Dependent Pathway. GSR, ROS
20  2021 A Nudibranch Marine Extract Selectively Chemosensitizes Colorectal Cancer Cells by Inducing ROS-Mediated Endoplasmic Reticulum Stress. 4-PBA, ER, ROS
21  2021 A pilot study of oxidative pathways in MS fatigue: randomized trial of N-acetyl cysteine. AE, MFIS, MRS
22  2021 A pilot study on intravenous N-Acetylcysteine treatment in patients with mild-to-moderate COVID19-associated acute respiratory distress syndrome. ARDS, SOFA
23  2021 A placebo-controlled, randomised pilot trial of N-acetylcysteine or placebo for cessation of tobacco smoking. ANZCTR, BMI
24  2021 A Protective Strategy to Counteract the Oxidative Stress Induced by Simulated Microgravity on H9C2 Cardiomyocytes. ROS, RPM
25  2021 A systematic review of N-acetylcysteine for treatment of acne vulgaris and acne-related associations and consequences: Focus on clinical studies. ---
26  2021 A Systematic Review of the Effect of N-Acetylcysteine on Serum Creatinine and Cystatin C Measurements. CI, WMD
27  2021 Aberrant ROS Mediate Cell Cycle and Motility in Colorectal Cancer Cells Through an Oncogenic CXCL14 Signaling Pathway. CRC, EMT, p-ERK, ROS
28  2021 Abscisic acid inhibited reactive oxygen species-mediated endoplasmic reticulum stress by regulating the PPAR-γ signaling pathway in ARDS mice. ABA, ARDS, ER, LPS, Nrf2, PPARgamma, ROS
29  2021 Absorption of N-acetylcysteine in Healthy and Mycoplasma gallisepticum-Infected Chickens. BW
30  2021 Acetylshikonin Induces Apoptosis in Human Colorectal Cancer HCT-15 and LoVo Cells via Nuclear Translocation of FOXO3 and ROS Level Elevation. DCF-DA, FACS, PI, ROS, TUNEL
31  2021 Activation of NRF2 and ATF4 Signaling by the Pro-Glutathione Molecule I-152, a Co-Drug of N-Acetyl-Cysteine and Cysteamine. ATF4
32  2021 Activation of the ROS/CncC and 20-Hydroxyecdysone Signaling Pathways Is Associated with Xanthotoxin-Induced Tolerance to lamda-Cyhalothrin in Spodoptera litura. CncC, MafK, ROS
33  2021 Activation of TLR4 induces severe acute pancreatitis-associated spleen injury via ROS-disrupted mitophagy pathway. ROS, SAP, TLR4
34  2021 Adjunct N-Acetylcysteine Treatment in Hospitalized Patients With HIV-Associated Tuberculosis Dampens the Oxidative Stress in Peripheral Blood: Results From the RIPENACTB Study Trial. HIV, TB
35  2021 Administration of N-acetylcysteine Plus Acetylsalicylic Acid Markedly Inhibits Nicotine Reinstatement Following Chronic Oral Nicotine Intake in Female Rats. ASA
36  2021 Adolescent exposure to delta-9-tetrahydrocannabinol and ethanol heightens sensitivity to fear stimuli. AUD, CUD, PFC, PTSD, THC
37  2021 Advanced Oxidation Protein Products Induce G1/G0-Phase Arrest in Ovarian Granulosa Cells via the ROS-JNK/p38 MAPK-p21 Pathway in Premature Ovarian Insufficiency. AOPPs, JNK, MAPK, POI, ROS, SD
38  2021 AHR/ROS-mediated mitochondria apoptosis contributes to benzo[a]pyrene-induced heart defects and the protective effects of resveratrol. AhR, BaP, ROS, RSV
39  2021 Airborne particulate matter (PM2.5) triggers ocular hypertension and glaucoma through pyroptosis. HTM, IOP, PM, ROS
40  2021 Algicidal effect of tryptoline against Microcystis aeruginosa: Excess reactive oxygen species production mediated by photosynthesis. ROS
41  2021 Alloreactive T cells deficient of the short-chain fatty acid receptor GPR109A induce less graft-versus-host disease. allo-HCT, GVHD, SCFA
42  2021 Alterations of mitochondrial dynamics, inflammation and mineralization potential of lipopolysaccharide-induced human dental pulp cells after exposure to N-acetyl cysteine, Biodentine or ProRoot MTA. E. coli, hDPCs, LPS, mtROS, RT-PCR
43  2021 Altered cytoskeletal arrangement in induced pluripotent stem cells (iPSCs) and motor neurons from patients with riboflavin transporter deficiency. alpha- and beta-TUB, iPSCs, MNs, RF, RTD
44  2021 Ameliorating effects of N-acetyl cysteine against early liver damage of radioiodine in rats. MDA, RAI
45  2021 Ameliorative effect of N-acetylcysteine against glyphosate-induced hepatotoxicity in adult male albino rats: histopathological, biochemical, and molecular studies. AST, GLP, MDA, PCNA
46  2021 Ameliorative effects of hesperidin and N-acetylcysteine against formaldehyde-induced-hemato- and genotoxicity. FA, HP
47  2021 An Activatable Near-Infrared Fluorescence Probe for in Vivo Imaging of Acute Kidney Injury by Targeting Phosphatidylserine and Caspase-3. AKI, CASP3, NIR, PS, SBR
48  2021 An antioxidant suppressed lung cellular senescence and enhanced pulmonary function in aged mice. ---
49  2021 An insight on safety, efficacy, and molecular docking study reports of N-acetylcysteine and its compound formulations. ---
50  2021 Anti-inflammatory and anti-apoptotic effects of N-acetylcysteine in diabetic rat corneal epithelium. CCAP-3, HCECs, IL, PARP, RAGE, STZ, TNF
51  2021 Antibacterial Polysiloxane Polymers and Coatings for Cochlear Implants. ---
52  2021 Antioxidant biocompatible composite collagen dressing for diabetic wound healing in rat model. CAT, Col, GCN, GO, GPx, ROS, SOD, STZ
53  2021 Antioxidant effects on hypoxia-induced oxidative stress and apoptosis in rat rotator cuff fibroblasts. HIF-1alpha, HO-1, MMP-2, PARP-1, RCFs, ROS, VEGF-beta
54  2021 Antioxidant interventions in autism spectrum disorders: A meta-analysis. ABC, ASD, CGIS, DBC, RBS, SRS
55  2021 Antioxidant supplements promote tumor formation and growth and confer drug resistance in hepatocellular carcinoma by reducing intracellular ROS and induction of TMBIM1. DEN, HCC, ROS
56  2021 Antioxidant treatment ameliorates prefrontal hypomyelination and cognitive deficits in a rat model of schizophrenia. PFC, SZ
57  2021 Antioxidant, histopathological and biochemical outcomes of short-term exposure to acetamiprid in liver and brain of rat: The protective role of N-acetylcysteine and S-methylcysteine. ACP, CAT, GST, LPO, SMC, TAC
58  2021 Antioxidants and pentoxifylline as coadjuvant measures to standard therapy to improve prognosis of patients with pneumonia by COVID-19. Apache II, COVID-19, GCS, LPO, MT, OS, Px, SAPS II, SOFA, TAC, Vit C, Vit E
59  2021 Antioxidants Promote Intestinal Tumor Progression in Mice. ---
60  2021 Antioxidants Supplementation Reduces Ceramide Synthesis Improving the Cardiac Insulin Transduction Pathway in a Rodent Model of Obesity. ALA, HPLC, IR
61  2021 Antrodia salmonea induces apoptosis and enhances cytoprotective autophagy in colon cancer cells. 3-MA, AOM, AS, ATG4B, AVOs, Bax, ERK, LC3-II, PI, ROS
62  2021 Arginine Deiminase Induces Immunogenic Cell Death and Is Enhanced by N-acetylcysteine in Murine MC38 Colorectal Cancer Cells and MDA-MB-231 Human Breast Cancer Cells In Vitro. ADI, ATP, BMDCs, CRT, HMGB1, ICD
63  2021 ARNT deficiency represses pyruvate dehydrogenase kinase 1 to trigger ROS production and melanoma metastasis. ARNT, CCCP, NQO1, PDK1
64  2021 Arsenic trioxide induces macrophage autophagy and atheroprotection by regulating ROS-dependent TFEB nuclear translocation and AKT/mTOR pathway. 3-MA, AS, ATO, ROS, TFEB
65  2021 Artemisinin Derivatives Inhibit Non-small Cell Lung Cancer Cells Through Induction of ROS-dependent Apoptosis/Ferroptosis. ART, DHA, NSCLC, TFRC
66  2021 Aryl hydrocarbon receptor engagement during redox alteration determines the fate of CD4+ T cells in C57BL/6 mice. AhR, BSO, FICZ
67  2021 Aspirin eugenol ester ameliorates paraquat-induced oxidative damage through ROS/p38-MAPK-mediated mitochondrial apoptosis pathway. AEE, ALI, CAT, GPx, MAPK, MDA, PQ, ROS, SOD
68  2021 Assessment of the correlation between oxidative stress and expression of MMP-2, TIMP-1 and COX-2 in human aortic smooth muscle cells. COX-2, ECM, HASMCs, MMP-2, SMCs
69  2021 Association of different Candida species with catheter-related candidemia, and the potential antifungal treatments against their adhesion properties and biofilm-forming capabilities. FZ, MF
70  2021 Association of heat shock protein A2 expression and sperm quality after N-acetyl-cysteine supplementation in astheno-terato-zoospermic infertile men. HSPA2, TCA
71  2021 Astaxanthin induces NADPH oxidase activation and receptor‑interacting protein kinase 1‑mediated necroptosis in gastric cancer AGS cells. ASX, LDH, MLKL, RIP1, ROS
72  2021 Astaxanthin Inhibits Interleukin-6 Expression in Cerulein/Resistin-Stimulated Pancreatic Acinar Cells. ASX, IL-6, ROS
73  2021 Atractylodin inhibits fructose-induced human podocyte hypermotility via anti-oxidant to down-regulate TRPC6/p-CaMK4 signaling. CAT, CD2AP, ROS, SOD, TRPC6
74  2021 Automated quantification of live articular chondrocyte fluorescent staining using a custom image analysis framework. MCB
75  2021 Autophagy impairment as a key feature for acetaminophen-induced ototoxicity. APAP
76  2021 Autophagy induced by H. pylori VacA regulated the survival mechanism of the SGC7901 human gastric cancer cell line. H. pylori, ROS, VacA
77  2021 Autophagy is involved in the replication of H9N2 influenza virus via the regulation of oxidative stress in alveolar epithelial cells. ---
78  2021 Azoxystrobin Impairs Neuronal Migration and Induces ROS Dependent Apoptosis in Cortical Neurons. AZOX, ROS
79  2021 Baseline serum amino acid levels predict treatment response to augmentation with N-acetylcysteine (NAC) in a bipolar disorder randomised trial. BD, MADRS
80  2021 BDE-47 induces nephrotoxicity through ROS-dependent pathways of mitochondrial dynamics in PK15 cells. ATP, MMP, PK-15, ROS
81  2021 beta-Naphthothiazolium-based ratiometric fluorescent probe with ideal pKa for pH imaging in mitochondria of living cells. CCCP, ICT
82  2021 Bidirectional role of reactive oxygen species during inflammasome activation in acrolein-induced human EAhy926 cells pyroptosis. 3-MA, NLRP3, ROS
83  2021 Biocompatible N-acetyl-nanoconstruct alleviates lipopolysaccharide-induced acute lung injury in vivo. ALI, Nano
84  2021 Biocompatible orthodontic cement with antibacterial capability and protein repellency. MPC, RMGIC, WSLs
85  2021 Bisphenol A Induces Accelerated Cell Aging in Murine Endothelium. BPA, MAECs, UPR
86  2021 Bisphenol A induces apoptosis and autophagy in murine osteocytes MLO-Y4: Involvement of ROS-mediated mTOR/ULK1 pathway. BafA1, BPA, HO-1, MDA, mTOR, Nrf2, ROS, SBI, ULK1
87  2021 Bisphenol A induces pyroptotic cell death via ROS/NLRP3/Caspase-1 pathway in osteocytes MLO-Y4. BPA, GSDMD-N, IL, LDH, MDA, mtROS, ROS, SOD
88  2021 Blue LED causes autophagic cell death in human osteosarcoma by increasing ROS generation and dephosphorylating EGFR. CAT, DPI, IP, LED, OS
89  2021 Blue light induces the nuclear translocation of neuropeptide receptor PAC1-R associated with the up-regulation of PAC1-R its own in reactive oxygen species associated way. 2-BP, NLS, ROS
90  2021 Bone marrow mononuclear cells boosts anti-cytogentical aberration effect of N-acetylcysteine and alpha-lipoic acid in rat's liver and bone marrow: implication of oxidative and inflammatory pathways. ALA, AST, BMMNCs, CAT, GPx, IL-10, IL-6, MDA, MNPCEs, SOD, TAC, TNF-alpha
91  2021 Bortezomib activation of mTORC1 pathway mediated by NOX2-drived reactive oxygen species results in apoptosis in primary dorsal root ganglion neurons. BIPN, BORT, DRG, ROS
92  2021 Bottom-up analysis of emergent properties of N-acetylcysteine as an adjuvant therapy for COVID-19. COVID-19
93  2021 Brassinin Inhibits Proliferation in Human Liver Cancer Cells via Mitochondrial Dysfunction. HCC, MAPK, PCNA, ROS
94  2021 Britannin, a sesquiterpene lactone induces ROS-dependent apoptosis in NALM-6, REH, and JURKAT cell lines and produces a synergistic effect with vincristine. ALL, CI, PBMCs, ROS, VCR
95  2021 Cadmium exposure triggers oxidative stress, necroptosis, Th1/Th2 imbalance and promotes inflammation through the TNF-alpha/NF-kappaB pathway in swine small intestine. Cd, Nec-1
96  2021 Cadmium induces renal inflammation by activating the NLRP3 inflammasome through ROS/MAPK/NF-kappaB pathway in vitro and in vivo. Cd, NLRP3, UCd, uNAG
97  2021 Cadmium triggers oxidative stress and mitochondrial injury mediated apoptosis in human extravillous trophoblast HTR-8/SVneo cells. Cd
98  2021 Calycosin Induces Gastric Cancer Cell Apoptosis via the ROS-Mediated MAPK/STAT3/NF-kappaB Pathway. Bcl-2, CDK2, cle, GC, NF-kappaB, PI, ROS, STAT3
99  2021 Can granulocyte colony stimulating factor (G-CSF) ameliorate acetaminophen-induced hepatotoxicity? ALP, AST, CAT, G-CSF, LDH, MDA, NO
100  2021 Cardiorespiratory and metabolic fitness indicators in novice volleyball trainees: effect of 1-week antioxidant supplementation with N-acetyl-cysteine/zinc/vitamin C. CRF, HIF-1alpha, TTE