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Abbreviation : NF-kappaB
Long Form : nuclear factor kappa-light-chain-enhancer of activated B cells
No. Year Title Co-occurring Abbreviation
2021 3'-Sialyllactose Protects SW1353 Chondrocytic Cells From Interleukin-1β-Induced Oxidative Stress and Inflammation. 3'-SL, IL-1beta, MAPK, MMP, OA, PI3K
2021 A strategy to prevent atherosclerosis via TNF receptor regulation. HAECs, ICAM-1, TNF-alpha, TNFR1, VCAM-1
2021 Ac2-26-Nanoparticles Induce Resolution of Intestinal Inflammation and Anastomotic Healing via Inhibition of NF-κB Signaling in a Model of Perioperative Colitis. ANXA1
2021 Accelerated Bone Regeneration by Adrenomedullin 2 Through Improving the Coupling of Osteogenesis and Angiogenesis via β-Catenin Signaling. ADM2, Akt, BMSCs, DO
2021 Adolescent stress sensitizes the adult neuroimmune transcriptome and leads to sex-specific microglial and behavioral phenotypes. CAS, GR, LPS
2021 Adrenomedullin 2 improves bone regeneration in type 1 diabetic rats by restoring imbalanced macrophage polarization and impaired osteogenesis. ADM2, AGEs, ALP, BMSC, DO, PPARgamma, T1DM
2021 Alprostadil alleviates liver injury in septic rats via TLR4/NF-κB pathway. Alp, CLP, TLR4, TNF-alpha
2021 Analysis of Cytotoxic Effects of Zerumbone in Malignant Glioblastoma Cells. GBM
2021 Analysis of interleukin-1 receptor associated kinase-3 (IRAK3) function in modulating expression of inflammatory markers in cell culture models: A systematic review and meta-analysis. IL-6, IRAK3, TNF-alpha
10  2021 Anti-cancer effects of Tranilast: An update. MAPK, PI3K, TGF-beta, TRN
11  2021 Anti-Inflammatory Effect of Auranofin on Palmitic Acid and LPS-Induced Inflammatory Response by Modulating TLR4 and NOX4-Mediated NF-κB Signaling Pathway in RAW264.7 Macrophages. IL, LPS, NO, NOX, PA, TLR
12  2021 Anti-Inflammatory Effects of a Polyphenol, Catechin-7,4'-O-Digallate, from Woodfordia uniflora by Regulating NF-κB Signaling Pathway in Mouse Macrophages. CDG, ImKCs, LPS, NO
13  2021 Anti-inflammatory Effects of Sanhuang-Siwu-Tang in Lipopolysaccharide-Stimulated RAW264.7 Macrophages and BV2 Microglial Cells. COX-2, IL-6, iNOS, LPS, MAPK, NO, PGE2, SST, TNF-alpha
14  2021 Anti-TNF treatment corrects IFN-γ-dependent proinflammatory signatures in Blau syndrome patient-derived macrophages. BS, iPSCs
15  2021 Antioxidant and anticancer potentials of edible flowers: where do we stand? AREs, Bax, ILs, MDA, NO, ROS, TNF
16  2021 Atrazine Inhalation Causes Neuroinflammation, Apoptosis and Accelerating Brain Aging. ATR, DMSO
17  2021 Auranofin-Mediated NRF2 Induction Attenuates Interleukin 1 Beta Expression in Alveolar Macrophages. AFN, AMs, BSO, IL, LPS, MH-S, Nrf2
18  2021 Biological Evaluation and Transcriptomic Analysis of Corylin as an Inhibitor of Osteoclast Differentiation. NF, NFATc1
19  2021 Camu-Camu Fruit Extract Inhibits Oxidative Stress and Inflammatory Responses by Regulating NFAT and Nrf2 Signaling Pathways in High Glucose-Induced Human Keratinocytes. AP-1, MAPK, NFAT, NQO1, Nrf2, ROS
20  2021 CD74 regulates cellularity and maturation of medullary thymic epithelial cells partially by activating the canonical NF-κB signaling pathway. MHC-II, mTECs, TCR, TECs
21  2021 Classical isoforms of protein kinase C (PKC) and Akt regulate the osteogenic differentiation of human dental follicle cells via both β-catenin and NF-κB. ALP, BMP-2, DFCs, PKC, PTHrP, siRNA
22  2021 Clofibrate, a Peroxisome Proliferator-Activated Receptor-Alpha (PPARα) Agonist, and Its Molecular Mechanisms of Action against Sodium Fluoride-Induced Toxicity. PPARalpha
23  2021 Common Transcriptional Program of Liver Fibrosis in Mouse Genetic Models and Humans. ERalpha, KEGG, TRANSFAC
24  2021 Crataegus laevigata Suppresses LPS-Induced Oxidative Stress during Inflammatory Response in Human Keratinocytes by Regulating the MAPKs/AP-1, NFκB, and NFAT Signaling Pathways. AP-1, CLE, LPS, MAPK, NFAT, ROS
25  2021 Critical role of microRNAs in host and influenza A (H1N1) virus interactions. IFNs, RIG-I
26  2021 Diabetes and Heart Failure: Multi-Omics Approaches. AGEs, Ca, PKC, PP1, ROS, SERCA2a
27  2021 Diacerein Inhibits Myopia Progression through Lowering Inflammation in Retinal Pigment Epithelial Cell. AKT, MFD
28  2021 Effect of ketamine on gene expression in zebrafish embryos. JAK/STAT, NMDA, PPAR, TGF-beta, Wnt
29  2021 Effects of Copper Nanoparticles on mRNA and Small RNA Expression in Human Hepatocellular Carcinoma (HepG2) Cells. ER, HMOX1
30  2021 Estrogen-related receptor-gamma influences Helicobacter pylori infection by regulating TFF1 in gastric cancer. ESRRG, GC, TFF1
31  2021 Evodiamine Inhibits Helicobacter pylori Growth and Helicobacter pylori-Induced Inflammation. AGS, CagA, H. pylori, IL, MAPK, SecA, VacA, WHO
32  2021 Excretory/secretory proteins of adult Toxocara canis induce changes in the expression of proteins involved in the NOD1-RIP2-NF-κB pathway and modulate cytokine production in mouse macrophages. ES, IL-1beta, NOD1, qRT-PCR, RIP2
33  2021 Exosomes from IL-1β-Primed Mesenchymal Stem Cells Inhibited IL-1β- and TNF-α-Mediated Inflammatory Responses in Osteoarthritic SW982 Cells. IL, MSC-Exo, MSCs, OA, TNF
34  2021 Exploring the role of polyphenols in rheumatoid arthritis. DMARD, IL, JNK, MAPK, NSAIDs, RA, TNF-alpha
35  2021 Exposure to second-hand cigarette smoke exacerbates the progression of osteoarthritis in a surgical induced murine model. DMM, MMP-13, OA, RA, SHS
36  2021 Expression, signal transduction, and function analysis of TIRAP and TRIF in Nile tilapia (Oreochromis niloticus). AP-1, IFN-beta, TLRs
37  2021 Fluoxetine as an anti-inflammatory therapy in SARS-CoV-2 infection. COVID-19, IL-6, IL-6R, IL6ST or gp130, NFKB1, SARS-CoV-2
38  2021 Gallic acid suppresses inflammation and oxidative stress through modulating Nrf2-HO-1-NF-κB signaling pathways in elastase-induced emphysema in rats. COPD, HO-1, PPE
39  2021 Garcinol Encapsulated Ph-Sensitive Biodegradable Nanoparticles: A Novel Therapeutic Strategy for the Treatment of Inflammatory Bowel Disease. ES100, GAR, IBD, IL, LDH, MPO, NPs
40  2021 Genomic locus proteomic screening identifies the NF-κB signaling pathway components NFκB1 and IKBKG as transcriptional regulators of Ripk3 in endothelial cells. GLoPro, RIPK3
41  2021 Geraniol isolated from lemon grass to mitigate doxorubicin-induced cardiotoxicity through Nrf2 and NF-κB signaling. IL-18, IL-1beta, Nrf2, TNF-alpha
42  2021 Glochidion ellipticum Wight extracts ameliorate dextran sulfate sodium-induced colitis in mice by modulating nuclear factor kappa-light-chain-enhancer of activated B cells signalling pathway. COX-2, DAI, DSS, FITC-dextran, iNOS, LPS, NO, ROS
43  2021 GPx-1-encoded adenoviral vector attenuates dopaminergic impairments induced by methamphetamine in GPx-1 knockout mice through modulation of NF-κB transcription factor. GPx, GPx-1-KO, MA, PDTC
44  2021 Gualou Guizhi Granule Suppresses LPS-Induced Inflammatory Response of Microglia and Protects against Microglia-Mediated Neurotoxicity in HT-22 via Akt/NF-κB Signaling Pathways. GLGZG, iNOS, LPS, NO
45  2021 Heat Shock Protein 27 Injection Leads to Caspase Activation in the Visual Pathway and Retinal T-Cell Response. HSP27
46  2021 HJC0416 Attenuates Fibrogenesis in Activated Hepatic Stellate Cells via STAT3 and NF-κB Pathways. HSC, STAT3
47  2021 IL-22 Signaling in the Tumor Microenvironment. IL, MAPK, mTOR, PI3K, STAT, TME
48  2021 Immunomodulatory effects of poly(I:C)-stimulated exosomes derived from chicken macrophages. ---
49  2021 Increased Toll-like Receptor-MyD88-NFκB-Proinflammatory neuroimmune signaling in the orbitofrontal cortex of humans with alcohol use disorder. AUD, CON, HMGB1, mRNA, MyD88, OFC, TLRs
50  2021 Increasing Oxygen Partial Pressures Induce a Distinct Transcriptional Response in Human PBMC: A Pilot Study on the "Normobaric Oxygen Paradox". HH, HIF-1alpha, MMP-9, NOP, PBMCs, VHH
51  2021 Inhibition of NF-κB signaling and HSP70/HSP90 proteins by newly synthesized hydrazide derivatives in arthritis model. JNK
52  2021 Inhibitory Effect of LGS and ODE Isolated from the Twigs of Syringa oblata subsp. dilatata on RANKL-Induced Osteoclastogenesis in Macrophage Cells. LGS, MAPK, mTOR, ODE, PI3K, RANKL
53  2021 Insulin-like growth factor binding protein 3 promotes radiosensitivity of oral squamous cell carcinoma cells via positive feedback on NF-κB/IL-6/ROS signaling. GSEA, IGFBP3, IL-6, IPA, IR, NAC, OSCC, ROS
54  2021 Interleukin-1α Is a Critical Mediator of the Response of Human Bronchial Fibroblasts to Eosinophilic Inflammation. HBF, IL-6, SBP-Ag
55  2021 Lactobacillus plantarum KSFY06 Prevents Inflammatory Response and Oxidative Stress in Acute Liver Injury Induced by D-Gal/LPS in Mice. ALI, ARE, ASC, AST, CAT, DPPH, GSH-Px, HO-1, IFN-gamma, IL, Keap1, LP-KSFY06, MDA, MPO, NO, SOD, T-AOC, TNF-alpha, Trx
56  2021 Lipopolysaccharide-Induced Nitric Oxide and Prostaglandin E2 Production Is Inhibited by Tellimagrandin II in Mouse and Human Macrophages. COX-2, LPS, MAPKs, NO, PGE2, TGII
57  2021 LncRNA CCDC26 Interacts with CELF2 Protein to Enhance Myeloid Leukemia Cell Proliferation and Invasion via the circRNA_ANKIB1/miR-195-5p/PRR11 Axis. CELF2, ML, PI3K, PRR11, RBP, RNA-IP
58  2021 LncRNA XIST promotes inflammation by downregulating GRα expression in the adenoids of children with OSAHS. GRalpha, IL, lncRNA, OSAHS, XIST
59  2021 Lutonarin from Barley Seedlings Inhibits the Lipopolysacchride-Stimulated Inflammatory Response of RAW 264.7 Macrophages by Suppressing Nuclear Factor-κB Signaling. BS, COX-2, IL, iNOS, LN, LPS, TNF
60  2021 Management of Acute Lung Injury: Palmitoylethanolamide as a New Approach. ALI, ARDS, IL, JNK, LPS, TNF, um-PEA
61  2021 Manganese-induced reactive oxygen species activate IκB kinase to upregulate YY1 and impair glutamate transporter EAAT2 function in human astrocytes in vitro. EAAT2, Mn, ROS, YY1
62  2021 Mangiferin mitigates di-(2-ethylhexyl) phthalate-induced testicular injury in rats by modulating oxidative stress-mediated signals, inflammatory cascades, apoptotic pathways, and steroidogenesis. cyt c, DEHP, HO-1, HSP70, MF, Nrf2, StAR, TAC
63  2021 Mechanism of MIR-210 mediated NF-κB pathway on cardiac ischemia-reperfusion injury. I/R, IL, LDH, miR-210
64  2021 Mechanistic dissection of spatial organization in NF-κB signaling pathways by hybrid simulations. TRAF
65  2021 miR-125b promotes the NF-κB-mediated inflammatory response in NAFLD via directly targeting TNFAIP3. NAFLD, TNFAIP3
66  2021 miR-708 Negatively Regulates TNFα/IL-1β Signaling by Suppressing NF-κB and Arachidonic Acid Pathways. AA, COX-2, IKKbeta, IL-1beta, miRNA, mPGES-1, RNAi, TNF-alpha
67  2021 Moringa isothiocyanate-1 regulates Nrf2 and NF-κB pathway in response to LPS-driven sepsis and inflammation. LPS, MIC-1, ROS
68  2021 Multifaceted roles of Toll-like receptors in acute kidney injury. AKI, IFNs, IL-1beta, PRRs, TLRs
69  2021 Nc886, a Novel Suppressor of the Type I Interferon Response Upon Pathogen Intrusion. AP-1, IFNs, IRF3, PKR
70  2021 NF-κB p65 regulates hepatic lipogenesis by promoting nuclear entry of ChREBP in response to a high carbohydrate diet. ChREBP, DNL, NAFLD
71  2021 Novel Insights into YB-1 Signaling and Cell Death Decisions. LPS
72  2021 Omega-3 Polyunsaturated Fatty Acids and the Intestinal Epithelium-A Review. COX, GPR, PPAR, PUFAs
73  2021 Oncogenetic landscape of lymphomagenesis in coeliac disease. CeD, EATL
74  2021 Orange peel extract reduces the inflammatory state of skeletal muscle after downhill running via an increase in IL-1RA. DR, IL-1ra, OPE, PMFs
75  2021 Overexpression of the receptor for advanced glycation end-products in the auditory cortex of rats with noise-induced hearing loss. IL-1beta, IL-6, MMP-9, RAGE, TNF-alpha
76  2021 Perspectives on Precision Medicine in Chronic Lymphocytic Leukemia: Targeting Recurrent Mutations-NOTCH1, SF3B1, MYD88, BIRC3. CLL, NOTCH1, SF3B1
77  2021 Polygonatum sibiricum polysaccharide prevents depression-like behaviors by reducing oxidative stress, inflammation, and cellular and synaptic damage. CORT, CUMS, GFAP, i.p, LPS, mTOR, p-Akt, PSP, TCM
78  2021 Potential mechanisms underlying the protective effects of Tricholoma matsutake singer peptides against LPS-induced inflammation in RAW264.7 macrophages. LPS, MAPK, ROS, SOD
79  2021 Powerful anti-inflammatory action of luteolin: Potential increase with IL-38. IL, JNK, ROS, TLR
80  2021 Protectin D1 reduces imiquimod-induced psoriasiform skin inflammation. IL, IMQ, PD1, TNF
81  2021 Qianliexin capsule exerts anti-inflammatory activity in chronic non-bacterial prostatitis and benign prostatic hyperplasia via NF-κB and inflammasome. BPH, CNP, IL, LUTS, QLX, TNF
82  2021 Quercetin modulates NRF2 and NF-κB/TLR-4 pathways to protect against isoniazid- and rifampicin-induced hepatotoxicity in vivo. ALP, ALT, AST, HMGB1, IFN-gamma, Nrf2, TB, TLR4
83  2021 Retinoprotective effect of agmatine in streptozotocin-induced diabetic rat model: avenues for vascular and neuronal protection : Agmatine in diabetic retinopathy. DR, GFAP, GLAST, GS, MAPKs, NMDAR1, NO, NOS, VEGF
84  2021 Role of Pirin, an Oxidative Stress Sensor Protein, in Epithelial Carcinogenesis. OS
85  2021 Role of Proprotein Convertase Subtilisin/Kexin Type 9 in the Pathogenesis of Graves' Orbitopathy in Orbital Fibroblasts. CAS, COX-2, GO, HIF-1alpha, HO-1, ICAM-1, IL-1beta, MnSOD, PCSK9, PPARgamma, TBII, Trx
86  2021 Rosavin suppresses osteoclastogenesis in vivo and in vitro by blocking the nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) and mitogen-activated protein kinase (MAPK) signaling pathways. ALP, BMMCs, BMSCs, c-fms, CTR, ERK, IkappaBalpha, JNK, MAPK, MMP-9, PMOP, RANK, RANKL, TRAF-6, TRAP
87  2021 Schaftoside Suppresses Pentylenetetrazol-Induced Seizures in Zebrafish via Suppressing Apoptosis, Modulating Inflammation, and Oxidative Stress. CAT, GPx1a, IL-1beta, IL-6, MnSOD, PTZ, SS, TCMs
88  2021 Sinapic acid ameliorates D-galactosamine/lipopolysaccharide-induced fulminant hepatitis in rats: Role of nuclear factor erythroid-related factor 2/heme oxygenase-1 pathways. ALF, ALT, AST, D-GalN, i.p, LPS, MDA, SA
89  2021 The Activation of ROS/NF-κB/MMP-9 Pathway Promotes Calcium-Induced Kidney Crystal Deposition. MMP-9, ROS
90  2021 The Effect of COVID-19 on NF-κB and Neurological Manifestations of Disease. COVID-19, SARS-CoV-2
91  2021 The flavonoids of okra insulates against oxidative stress, neuroinflammation and restores BDNF levels in Aβ1-42 induced mouse model of Alzheimer's disease. BDNF, CREB, ERK, FOF, GSH-Px, GSK-3beta, IL-1beta, PI3K, SOD, T-AOC, TNF-alpha
92  2021 The Neuroinflammatory and Neurotoxic Potential of Palmitic Acid Is Mitigated by Oleic Acid in Microglial Cells and Microglial-Neuronal Co-cultures. IL-6, iNOS, OA, PA, TNF-alpha
93  2021 The Role of NLRP3 Inflammasome in Cerebrovascular Diseases Pathology and Possible Therapeutic Targets. IFN, NOD, Nrf2, PI3K, PYD, ROS, SIRT, TXNIP
94  2021 The Role of Pyroptosis in Ischemic and Reperfusion Injury of the Heart. I/R, TLR
95  2021 The SARS-CoV-2 spike protein subunit S1 induces COVID-19-like acute lung injury in Κ18-hACE2 transgenic mice and barrier dysfunction in human endothelial cells. ACE2, ALI, BALF, S1SP, SP, STAT3, TER, WT
96  2021 Therapeutic effect of and mechanisms underlying the effect of miR-195-5p on subarachnoid hemorrhage-induced vasospasm and brain injury in rats. eNOS, iNOS, p-Ikappa Balpha, p-NF-kappaB, SAH, TNF-alpha
97  2021 Therapeutic Role of Protein Tyrosine Phosphatase 1B in Parkinson's Disease via Antineuroinflammation and Neuroprotection In Vitro and In Vivo. BDNF, COX-2, ER, iNOS, pCREB, PD, PTP1B, TH
98  2021 TIFA has dual functions in Helicobacter pylori-induced classical and alternative NF-κB pathways. cIAP1, TAK1, TRAF
99  2021 Toll-like receptor 4 antagonist FP7 alleviates lipopolysaccharide-induced septic shock via NF-kB signaling pathway. BMDMs, LPS, TLR4
100  2021 Transcriptomic Hallmarks of Ischemia-Reperfusion Injury. GO, IRI, KEGG, TNF