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[Related PubMed/MEDLINE]
Total Number of Papers: 442
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| Abbreviation |
: NOD2 |
| Long Form |
: nucleotide-binding oligomerization domain 2 |
|
| No. |
Year |
Title |
Co-occurring Abbreviation |
| 1 |
2023 |
The crosstalk between microbial sensors ELMO1 and NOD2 shape intestinal immune responses. |
CD, EDMs, MDP |
| 2 |
2023 |
Vimentin affects inflammation and neutrophil recruitment in airway epithelium during Streptococcus suis serotype 2 infection. |
IL-6, KC, SS2, STEC, TNF-alpha |
| 3 |
2022 |
Activation of nucleotide-binding oligomerization domain 2 by muramyl dipeptide negatively regulates Toll-like receptor 9-mediated colonic inflammation through the induction of deubiquitinating enzyme A expression. |
CD, DCs, DSS, DUBA, IBD, IFN, ISGs, TLRs |
| 4 |
2022 |
Association of polymorphous light eruption with NOD-2 and TLR-5 gene polymorphisms. |
aGVHD, LC, PLE, SNPs, TLR5, UVB |
| 5 |
2022 |
Bacillus-Based Direct-Fed Microbial Reduces the Pathogenic Synergy of a Coinfection with Salmonella enterica Serovar Choleraesuis and Porcine Reproductive and Respiratory Syndrome Virus. |
DFM, IL-1, PRRSV, TREM-1 |
| 6 |
2022 |
Covalently Conjugated NOD2/TLR7 Agonists Are Potent and Versatile Immune Potentiators. |
TLR7 |
| 7 |
2022 |
Cytosolic HMGB1 Mediates LPS-Induced Autophagy in Microglia by Interacting with NOD2 and Suppresses Its Proinflammatory Function. |
DAMP, HMGB1, KD, LC3, LPS |
| 8 |
2022 |
Discovery of Desmuramylpeptide NOD2 Agonists with Single-Digit Nanomolar Potency. |
--- |
| 9 |
2022 |
Effect of Toll-like receptor-2, -4, -5, -7, and NOD2 stimulation on potassium channel conductance in intestinal epithelial cells. |
IBD, IECs, TLRs, TRAM-34 |
| 10 |
2022 |
Genetic and Clinical Features of Blau Syndrome among Chinese Patients with Uveitis. |
ACMG |
| 11 |
2022 |
Identification of key genes for hypertrophic cardiomyopathy using integrated network analysis of differential lncRNA and gene expression. |
AKT1, AMPD2, ATG16L1, ATG5, CARD9, GEO, GNAI1, GNAI2, GNAI3, GNAS, GNB1, GNG12, GNG13, GNG2, GNGT1, GO, HCM, IFIH1, KEGG, lncRNAs, MAVS, MIR22HG, mRNAs, NOD1, PPI, RIPK2, SERPINF1, SNHG12, TAF12, TBK1, UNKL, vWF, WDR81 |
| 12 |
2022 |
Impact of antibiotic perturbation on fecal viral communities in mice. |
IBD |
| 13 |
2022 |
Interleukin 32 participates in cardiomyocyte-induced oxidative stress, inflammation and apoptosis during hypoxia/reoxygenation via the NOD2/NOX2/MAPK signaling pathway. |
IL, MIRI, NOX2 |
| 14 |
2022 |
It is not NOD2 - genetic and clinical risk factors for postoperative complications following ileocolic resection in Crohn's disease. |
CD, SNP |
| 15 |
2022 |
Macroglobulinemia and Autoinflammatory Disease. |
MyD88, SchS, WM |
| 16 |
2022 |
Mucosal Adjuvants Delivered by a Mucoadhesive Patch for Sublingual Administration of Subunit Vaccines. |
IL, KC, TLR |
| 17 |
2022 |
Muramyl dipeptide-based analogs as potential anticancer compounds: Strategies to improve selectivity, biocompatibility, and efficiency. |
MDP |
| 18 |
2022 |
Neuroinflammation-Related Proteins NOD2 and Spp1 Are Abnormally Upregulated in Amyotrophic Lateral Sclerosis. |
AD, ALS, FTD, HCs |
| 19 |
2022 |
NOD2 is involved in regulating odontogenic differentiation of DPSCs suppressed by MDP through NF-kappaB/p65 signaling. |
DMP1, DPSCs, DSPP, MDP, NLR |
| 20 |
2022 |
NOD2 Signaling Circuitry during Allergen Sensitization Does Not Worsen Experimental Neutrophilic Asthma but Promotes a Th2/Th17 Profile in Asthma Patients but Not Healthy Subjects. |
AAI, DC, MDP |
| 21 |
2022 |
NOD2 signaling in CD11c + cells is critical for humoral immune responses during oral vaccination and maintaining the gut microbiome. |
rLA |
| 22 |
2022 |
NOD2 Versus MEFV: Differential Diagnosis of Yao Syndrome and Familial Mediterranean Fever. |
FMF, HPFS, MEFV |
| 23 |
2022 |
NOD2-RIP2 signaling alleviates microglial ROS damage and pyroptosis via ULK1-mediated autophagy during Streptococcus pneumonia infection. |
--- |
| 24 |
2022 |
Novel Scaffolds for Modulation of NOD2 Identified by Pharmacophore-Based Virtual Screening. |
--- |
| 25 |
2022 |
Palmitoylation restricts SQSTM1/p62-mediated autophagic degradation of NOD2 to modulate inflammation. |
--- |
| 26 |
2022 |
Peptidoglycan-Like Components in Z-100, Extracted from Mycobacterium tuberculosis Strain Aoyama B, Increase IL-12p40 via NOD2. |
--- |
| 27 |
2022 |
Phosphorylation of muramyl peptides by NAGK is required for NOD2 activation. |
MDP, NAGK, PGN, PRRs |
| 28 |
2022 |
Polymorphisms in Pattern Recognition Receptor Genes Are Associated with Respiratory Disease Severity in Pig Farms. |
APP, GW, Mhp, NLRP3, SPES, TLR5-1205T |
| 29 |
2022 |
Postbiotic muramyl dipeptide alleviates colitis via activating autophagy in intestinal epithelial cells. |
DSS, MDP |
| 30 |
2022 |
Potential Benefits of TNF Targeting Therapy in Blau Syndrome, a NOD2-Associated Systemic Autoinflammatory Granulomatosis. |
MDP |
| 31 |
2022 |
The role of NOD2 in intestinal immune response and microbiota modulation: A therapeutic target in inflammatory bowel disease. |
IBD, PPR |
| 32 |
2021 |
A novel mutation in early-onset sarcoidosis/Blau syndrome: an association with Propionibacterium acnes. |
BS, EOS, P. acnes |
| 33 |
2021 |
Association of rs3135500 and rs3135499 Polymorphisms in the MicroRNA-binding Site of Nucleotide-binding Oligomerization Domain 2 (NOD2) Gene with Susceptibility to Rheumatoid Arthritis. |
CRP, ESR, HRM, RA, SNPs |
| 34 |
2021 |
Blue Light Induces Impaired Autophagy through Nucleotide-Binding Oligomerization Domain 2 Activation on the Mouse Ocular Surface. |
KO, ROS, WT |
| 35 |
2021 |
Expansion of Phenotypic and Genotypic Spectrum in Yao Syndrome: A Case Series. |
YAOS |
| 36 |
2021 |
Identification and functional analysis of NOD2 and its two splicing variants associated with a novel pattern of signal regulation in teleost fishes. |
CARD, LRR, MDP |
| 37 |
2021 |
IL-6 effector function of group 2 innate lymphoid cells (ILC2) is NOD2 dependent. |
IL-5, MDP |
| 38 |
2021 |
Ileocolonic Healing After Extended Small Bowel Resection in Mice: NOD2 Deficiency Impairs Anastomotic Healing and Postoperative Outcome. |
ICR, KO |
| 39 |
2021 |
Immune Modulation of Allergic Asthma by Early Pharmacological Inhibition of RIP2. |
HDM, RIP2 |
| 40 |
2021 |
Inborn Errors in the LRR Domain of Nod2 and Their Potential Consequences on the Function of the Receptor. |
ER, PRR |
| 41 |
2021 |
Influence of NOD-like receptor 2 gene polymorphisms on muramyl dipeptide induced pro-inflammatory response in patients with active pulmonary tuberculosis and household contacts. |
HC, HHC, MDP, QFT-ve HHC, RFLP |
| 42 |
2021 |
Knockdown of circular RNA hsa_circ_0003204 inhibits oxidative stress and apoptosis through the miR-330-5p/Nod2 axis to ameliorate endothelial cell injury induced by low-density lipoprotein. |
AS, HAECs, MDA, ox-LDL, qRT-PCR, ROS, SOD |
| 43 |
2021 |
Mannosylated adamantane-containing desmuramyl peptide recognition by the NOD2 receptor: a molecular dynamics study. |
LRR, MDP, NOD |
| 44 |
2021 |
Multiple Cranial Neuropathies and Pachymeningitis in a Patient With a Pathogenic Nucleotide-Binding Oligomerization Domain 2 Polymorphism. |
--- |
| 45 |
2021 |
New insights into genetic characteristics between multiple myeloma and COVID-19: An integrative bioinformatics analysis of gene expression omnibus microarray and the cancer genome atlas data. |
COVID-19, COX6C, DEGs, MM |
| 46 |
2021 |
NOD2 deficiency confers a pro-tumorigenic macrophage phenotype to promote lung adenocarcinoma progression. |
PDEIRGs |
| 47 |
2021 |
NOD2 deficiency protects mice from the development of adoptive transfer colitis through the induction of regulatory T cells expressing forkhead box P3. |
--- |
| 48 |
2021 |
NOD2-mediated P2Y12 upregulation increases platelet activation and thrombosis in sepsis. |
CLP |
| 49 |
2021 |
Nodosome Inhibition as a Novel Broad-Spectrum Antiviral Strategy against Arboviruses, Enteroviruses, and SARS-CoV-2. |
COVID-19, RIPK2, SARS-CoV-2, ZIKV |
| 50 |
2021 |
Staphylococcus aureus membrane vesicles contain immunostimulatory DNA, RNA and peptidoglycan that activate innate immune receptors and induce autophagy. |
MAMPs, MVs, PRRs, sRNA, TLR |
| 51 |
2021 |
Strong association of common variants in the miRNA-binding site of NOD2 gene with clinicopathological characteristics and disease activity of systemic lupus erythematosus. |
HRM, SLE, SNPs |
| 52 |
2021 |
Structural Elucidation of Inter-CARD Interfaces involved in NOD2 Tandem CARD Association and RIP2 Recognition. |
CARDs, RIP2 |
| 53 |
2021 |
Structural Fine-Tuning of Desmuramylpeptide NOD2 Agonists Defines Their In Vivo Adjuvant Activity. |
--- |
| 54 |
2021 |
Structural localization of pathogenic mutations in the central nucleotide-binding domain (NBD) of nucleotide-binding oligomerization domain-2 (NOD2) protein and their inference in inflammatory disorders. |
NBD |
| 55 |
2021 |
Survey of Candidate Single-Nucleotide Polymorphisms in SLC11A1, TLR4, NOD2, PGLYRP1, and IFNgamma in Ankole Longhorn Cattle in Central Region of Uganda to Determine Their Role in Mycobacterium avium Subspecies paratuberculosis Infection Outcome. |
IFNgamma, JD, MAP, PGLYRP1, SLC11A1, SNPs, TLR4 |
| 56 |
2021 |
Thalidomide may be an effective drug for Blau syndrome: a case report. |
BS, TNF |
| 57 |
2021 |
The Paratuberculosis Paradigm Examined: A Review of Host Genetic Resistance and Innate Immune Fitness in Mycobacterium avium subsp. Paratuberculosis Infection. |
CD, JD, MAP, MHC-II, SLC11A1, TLR |
| 58 |
2021 |
Tofacitinib effectiveness in Blau syndrome: a case series of Chinese paediatric patients. |
BS, CRP, ESR, JAK |
| 59 |
2021 |
Type I Interferons Are Involved in the Intracellular Growth Control of Mycobacterium abscessus by Mediating NOD2-Induced Production of Nitric Oxide in Macrophages. |
IFNAR, IFNs, Mab, NO, NTM, TBK1 |
| 60 |
2021 |
Ubiquitination of ATF6 by disease-associated RNF186 promotes the innate receptor-induced unfolded protein response. |
ATF6, IBD, PRRs, RNF186, UPR |
| 61 |
2021 |
Vimentin Regulates Chemokine Expression and NOD2 Activation in Brain Endothelium during Group B Streptococcal Infection. |
hCMEC, IL-8, MDP |
| 62 |
2021 |
Vitamin D Modulation of the Innate Immune Response to Paediatric Respiratory Pathogens Associated with Acute Lower Respiratory Infections. |
ALRIs, CXCL10, HNP, IL, RANTES, TLR2, TNF-alpha |
| 63 |
2021 |
Yao Syndrome: A Potential Role and Association of Vasoactive Intestinal Peptide with NOD2. |
VIP |
| 64 |
2020 |
Aggressive periodontitis and NOD2 variants. |
AgP |
| 65 |
2020 |
Amphiphilic desmuramyl peptides for the rational design of new vaccine adjuvants: Synthesis, invitro modulation of inflammatory response and molecular docking studies. |
DMPs, MDP, TNF-alpha |
| 66 |
2020 |
ATG16L1 negatively regulates RICK/RIP2-mediated innate immune responses. |
ATG16L1, CD, DCs, NF-kappaB, TLRs |
| 67 |
2020 |
Bioinformatics analysis of prognostic value of PITX1 gene in breast cancer. |
ER, NPI, PR, SBR |
| 68 |
2020 |
Blau Syndrome and Early-Onset Sarcoidosis: A Six Case Series and Review of the Literature. |
BS, EOS |
| 69 |
2020 |
Blau Syndrome: NOD2-related systemic autoinflammatory granulomatosis. |
BCG, iPS, MDP, TNF-alpha |
| 70 |
2020 |
Dietary muramidase degrades bacterial peptidoglycan to NOD-activating muramyl dipeptides and reduces duodenal inflammation in broiler chickens. |
MDP, PGN |
| 71 |
2020 |
Extracellular Histone H3 Induces Pyroptosis During Sepsis and May Act Through NOD2 and VSIG4/NLRP3 Pathways. |
ELISA, GSDMD, IL, LPS, NLR, NLRP3, RIP2, VSIG4 |
| 72 |
2020 |
First-in-human phase I clinical trial of the NY-ESO-1 protein cancer vaccine with NOD2 and TLR9 stimulants in patients with NY-ESO-1-expressing refractory solid tumors. |
AEs, CHP, NY-ESO-1, SD |
| 73 |
2020 |
GSK669, a NOD2 receptor antagonist, inhibits thrombosis and oxidative stress via targeting platelet GPVI. |
CRP, GPVI, MDA, ROS, SOD, SPR |
| 74 |
2020 |
Immunologic Complications and Graft Survival in Crohn's Disease and NOD2 Mutant Non-Crohn's Disease Adult Recipients Following Intestine Transplantation. |
CD |
| 75 |
2020 |
Innate immune receptor NOD2 mediates LGR5+ intestinal stem cell protection against ROS cytotoxicity via mitophagy stimulation. |
ISC, KO, LGR5, MDP, NF-kappaB, ROS |
| 76 |
2020 |
Lactobacillus reuteri 5454 and Bifidobacterium animalis ssp. lactis 5764 improve colitis while differentially impacting dendritic cells maturation and antimicrobial responses. |
DC, TNBS |
| 77 |
2020 |
Ligustrazine ameliorates acute kidney injury through downregulation of NOD2‑mediated inflammation. |
AKI |
| 78 |
2020 |
New chimeric TLR7/NOD2 agonist is a potent adjuvant to induce mucosal immune responses. |
PRR, TLR7 |
| 79 |
2020 |
NOD2 Influences Trajectories of Intestinal Microbiota Recovery After Antibiotic Perturbation. |
Nod2-KO, WT |
| 80 |
2020 |
NOD2 inhibits tumorigenesis and increases chemosensitivity of hepatocellular carcinoma by targeting AMPK pathway. |
AMP, DEN, HCC |
| 81 |
2020 |
NOD2 regulates microglial inflammation through the TAK1-NF-kappaB pathway and autophagy activation in murine pneumococcal meningitis. |
shRNA |
| 82 |
2020 |
Nucleotide-binding oligomerization domain protein 2 deficiency enhances CHOP expression and plaque necrosis in advanced atherosclerotic lesions. |
ATF6, ER, VSMCs |
| 83 |
2020 |
Ophthalmological treatment of early-onset sarcoidosis/Blau syndrome in a Colombian child: A case report. |
BS |
| 84 |
2020 |
PNPLA3 polymorphisms are associated with raised alanine aminotransferase levels in hepatitis C virus genotype 3. |
ALT, HCV, IL28B, RIG-I, SNPs, TLR7 |
| 85 |
2020 |
Probiotics exert reciprocal effects on autophagy and interleukin-1beta expression in Salmonella-infected intestinal epithelial cells via autophagy-related 16L1 protein. |
ATG16L1, BL, IECs, IL-1beta, LC3, LGG, VDR |
| 86 |
2020 |
Sphingosine-1-phosphate signal transducer and activator of transcription 3 signaling pathway contributes to baicalein-mediated inhibition of dextran sulfate sodium-induced experimental colitis in mice. |
DSS, p-STAT3, S1PR1, SphK1 |
| 87 |
2020 |
T cell-intrinsic role for Nod2 in protection against Th17-mediated uveitis. |
--- |
| 88 |
2020 |
The Role of the Bacterial Muramyl Dipeptide in the Regulation of GLP-1 and Glycemia. |
GLP-1, MDP |
| 89 |
2020 |
The roles and functions of Paneth cells in Crohn's disease: A critical review. |
ATG16L1, CASP8, CD, HD-6, HD5, HDACs, IRGM, LRRK2, PCs, Wnt, XBP1 |
| 90 |
2020 |
Tle1 attenuates hepatic ischemia/reperfusion injury by suppressing NOD2/NF-kappaB signaling. |
I/R, Tle1 |
| 91 |
2020 |
TRIM22 inhibits endometrial cancer progression through the NOD2/NF‑kappaB signaling pathway and confers a favorable prognosis. |
EnC, NF, TRIM22 |
| 92 |
2020 |
Ubiquitin-dependent and -independent functions of OTULIN in cell fate control and beyond. |
DUBs, ER, LUBAC, OTU, TLR, TNFR1 |
| 93 |
2019 |
Antibody neutralization of microbiota-derived circulating peptidoglycan dampens inflammation and ameliorates autoimmunity. |
mAb, PGN |
| 94 |
2019 |
Association between nucleotide-binding oligomerization domain protein 2 (NOD2) gene polymorphisms and Parkinson's disease (PD) susceptibility. |
HWE, OR, PD, SNPs |
| 95 |
2019 |
Autoinflammatory disease with focus on NOD2-associated disease in the era of genomic medicine. |
MEFV, SAIDs |
| 96 |
2019 |
Bilateral congenital macular coloboma and cataract: A case report. |
FZD4 |
| 97 |
2019 |
Blau Syndrome Associated with Nucleotide-binding Oligomerization Domain Containing 2 Mutation in a Baby from Malaysia. |
BS |
| 98 |
2019 |
Colorectal carcinoma in the course of inflammatory bowel diseases. |
CRC, IBD, TLR |
| 99 |
2019 |
Common NOD2 Risk Variants as Major Susceptibility Factors for Bacterial Infections in Compensated Cirrhosis. |
BIs, CSPH |
| 100 |
2019 |
Correlation between toll-like receptor 4 and nucleotide-binding oligomerization domain 2 (NOD2) and pathological severity in dogs with chronic gastrointestinal diseases. |
TLR4 |
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