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Abbreviation : OGD
Long Form : oxygen-glucose deprivation
No. Year Title Co-occurring Abbreviation
2021 A Feedback Loop Involving MicroRNA-150 and MYB Regulates VEGF Expression in Brain Microvascular Endothelial Cells After Oxygen Glucose Deprivation. BMVECs, miR-150, VEGF
2021 A novel RIP1/RIP3 dual inhibitor promoted OPC survival and myelination in a rat neonatal white matter injury model with hOPC graft. OPCs, RIP1 and RIP3, WMI
2021 A Scalable Method to Study Neuronal Survival in Primary Neuronal Culture with Single-cell and Real-Time Resolution. ---
2021 Aagab acts as a novel regulator of NEDD4-1-mediated Pten nuclear translocation to promote neurological recovery following hypoxic-ischemic brain damage. HIBD, HIE, NEDD4-1, PTEN
2021 Activation of type 4 metabotropic glutamate receptor attenuates oxygen and glucose deprivation-induced apoptosis in human neural stem cells via inhibition of ASK1-p38 signaling pathway. CNS, HIBI, hNSCs, NSCs
2021 Adipose-Derived Mesenchymal Stem Cells-Derived Exosomes Carry MicroRNA-671 to Alleviate Myocardial Infarction Through Inactivating the TGFBR2/Smad2 Axis. AD-MSCs, Exo, MI, miRNAs, MSCs, TGFBR2
2021 Alisol A 24-acetate protects against brain microvascular endothelial cells injury through inhibiting miR-92a-3p/tight junctions axis. AA, BBB, BMECs, LDH, TJs, ZO-1
2021 Alisol A 24-acetate protects oxygen-glucose deprivation-induced brain microvascular endothelial cells against apoptosis through miR-92a-3p inhibition by targeting the B-cell lymphoma-2 gene. Bax, Bcl-2, BMECs
2021 AMPK/SIRT1 Pathway is Involved in Arctigenin-Mediated Protective Effects Against Myocardial Ischemia-Reperfusion Injury. AMI/R
10  2021 An inhibitory and beneficial effect of chlorpromazine and promethazine (C + P) on hyperglycolysis through HIF-1α regulation in ischemic stroke. GLUT, LDH, MCAO, NADPH, PFK-1, ROS
11  2021 Astragaloside and/or Hydroxysafflor Yellow A Attenuates Oxygen-Glucose Deprivation-Induced Cultured Brain Microvessel Endothelial Cell Death through Downregulation of PHLPP-1. BMECs, HSYA
12  2021 AT1R/GSK-3β/mTOR Signaling Pathway Involved in Angiotensin II-Induced Neuronal Apoptosis after HIE Both In Vitro and In Vivo. Ang II, HIE
13  2021 Baicalein ameliorates ischemic brain damage through suppressing proinflammatory microglia polarization via inhibiting the TLR4/NF-κB and STAT1 pathway. LPS
14  2021 BCL-6 promotes the methylation of miR-34a by recruiting EZH2 and upregulating CTRP9 to protect ischemic myocardial injury. AMI, BCL6, CTRP9, EZH2, miR-34a
15  2021 BDNF promotes neuronal survival after neonatal hypoxic-ischemic encephalopathy by up-regulating Stx1b and suppressing VDAC1. BDNF, HI, HIE, IHC, qRT-PCR, TTC, WB
16  2021 Berberine exerts neuroprotective activities against cerebral ischemia/reperfusion injury through up-regulating PPAR-γ to suppress NF-κB-mediated pyroptosis. BBR, I/R
17  2021 BK Channel-Mediated Microglial Phagocytosis Alleviates Neurological Deficit After Ischemic Stroke. DMSO, tMCAO
18  2021 Bone marrow mesenchymal stem cells-derived extracellular vesicles carrying microRNA-221-3p protect against ischemic stroke via ATF3. ATF3, BMSCs, IS, MCAO, miR-221-3p
19  2021 C-Type Natriuretic Peptide Ameliorates Vascular Injury and Improves Neurological Outcomes in Neonatal Hypoxic-Ischemic Brain Injury in Mice. BMECs, CNP, HI, IgG
20  2021 Carbonyl Reductase 1 Attenuates Ischemic Brain Injury by Reducing Oxidative Stress and Neuroinflammation. 4-HNE, CBR1
21  2021 Catalpol Protects Against Spinal Cord Injury in Mice Through Regulating MicroRNA-142-Mediated HMGB1/TLR4/NF-κB Signaling Pathway. CTP, ROS, SCI
22  2021 CDK5 inhibition protects against OGDR induced mitochondrial fragmentation and apoptosis through regulation of Drp1S616 phosphorylation. Cdk5, Drp1, OGDR
23  2021 Celastrol exerts a neuroprotective effect by directly binding to HMGB1 protein in cerebral ischemia-reperfusion. CEL, cel-p, CETSA, HMGB1, I/R, MCAO, TMT
24  2021 cGAS knockdown promotes microglial M2 polarization to alleviate neuroinflammation by inhibiting cGAS-STING signaling pathway in cerebral ischemic stroke. cGAS, IS, MCAO, OIDs, STING
25  2021 CircTYW1 serves as a sponge for microRNA-380 in accelerating neurological recovery following spinal cord injury via regulating FGF9. circRNAs, miR-380, SCI
26  2021 Circular RNA circPHC3 Promotes Cell Death and Apoptosis in Human BMECs After Oxygen Glucose Deprivation via miR-455-5p/TRAF3 Axis in vitro. BMECs
27  2021 Circular RNA circ_0010729 Knockdown Attenuates Oxygen-Glucose Deprivation-Induced Human Cardiac Myocytes Injury by miR-338-3p/CALM2 Axis. CALM2, miR-338-3p
28  2021 Circular RNA TTC3 regulates cerebral ischemia-reperfusion injury and neural stem cells by miR-372-3p/TLR4 axis in cerebral infarction. CIR, circRNAs, circTTC3, LDH, MCAO/R, NSCs, TLR4
29  2021 Circular RNA _NLRP1 targets mouse microRNA-199b-3p to regulate apoptosis and pyroptosis of hippocampal neuron under oxygen-glucose deprivation exposure. ERK, GSDMD, IF, LDH, MAPK, sh
30  2021 Comparative analysis of spreading depolarizations in brain slices exposed to osmotic or metabolic stress. aCSF, LFP, SDs
31  2021 Contribution of TRPC Channels in Neuronal Excitotoxicity Associated With Neurodegenerative Disease and Ischemic Stroke. TRPC
32  2021 CPI-1189 protects neuronal cells from oxygen glucose deprivation/re-oxygenation-induced oxidative injury and cell death. ---
33  2021 Curcumin Alleviates Cerebral Ischemia-reperfusion Injury by Inhibiting NLRP1-dependent Neuronal Pyroptosis. caspase-1, GSDMD, MCAO, NLRP1
34  2021 Curcumin Derivative Cur20 Attenuated Cerebral Ischemic Injury by Antioxidant Effect and HIF-1α/VEGF/TFEB-Activated Angiogenesis. RBMECs, rUCCAO, VaD
35  2021 Decreased neuronal synaptosome associated protein 29 contributes to poststroke cognitive impairment by disrupting presynaptic maintenance. MCAO, RRP, SNAP29
36  2021 Deletion of Protocadherin Gamma C3 Induces Phenotypic and Functional Changes in Brain Microvascular Endothelial Cells In Vitro. BBB, BMECs, CNS, ERK, KO, TNF-alpha
37  2021 Design, synthesis, and neuroprotective effects of novel hybrid compounds containing edaravone analogue and 3-n-butylphthalide ring-opened derivatives. BBB, NBP
38  2021 Dexmedetomidine and Netrin-1 Combination Therapy Inhibits Endoplasmic Reticulum Stress by Regulating the ERK5/MEF2A Pathway to Attenuate Cerebral Ischemia Injury. MCAO, OPS
39  2021 Dexmedetomidine hydrochloride inhibits hepatocyte apoptosis and inflammation by activating the lncRNA TUG1/miR-194/SIRT1 signaling pathway. DEX
40  2021 Differentially regulated pools of aquaporin-4 (AQP4) proteins in the cerebral cortex revealed by biochemical fractionation analyses. AQP4, DRM
41  2021 Diterpene Ginkgolides Meglumine Injection inhibits apoptosis induced by optic nerve crush injury via modulating MAPKs signaling pathways in retinal ganglion cells. DGMI, ONC, RGCs
42  2021 Downregulation of lncRNA SNHG14 alleviates neurons injury by modulating the miR-181c-5p/BMF axis in ischemic stroke. BMF, IS, MCAO, SNHG14
43  2021 Early Growth Response Protein 1 Knockdown Alleviates the Cerebral Injury in Rats with Intracerebral Hemorrhage (ICH) via STAT3/NF-κB Pathway by Reducing RXRα Acetylation Level. BBB, BMECs, Egr-1, ICH, TEER
44  2021 Effect of Sutellarin on Neurogenesis in Neonatal Hypoxia-Ischemia Rat Model: Potential Mechanisms of Action. HI, p75NTR, Scu
45  2021 Electroacupuncture promotes the recovery of rats with spinal cord injury by suppressing the Notch signaling pathway via the H19/EZH2 axis. EA, GFAP, NSC, SCI
46  2021 Enolase2 and enolase1 cooperate against neuronal injury in stroke model. AS, ENO1, ENO2, KD, MCAO
47  2021 Exosomes derived from human amniotic fluid mesenchymal stem cells alleviate cardiac fibrosis via enhancing angiogenesis in vivo and in vitro. alpha-SMA, ECM, hAFMSC, HIF-1alpha, HUVECs, ISO, MSC, PBS, VEGF
48  2021 Exosomes derived from hypoxic bone marrow mesenchymal stem cells rescue OGD-induced injury in neural cells by suppressing NLRP3 inflammasome-mediated pyroptosis. LDH
49  2021 Exosomes from Human Umbilical Vein Endothelial Cells Ameliorate Ischemic Injuries by Suppressing the RNA Component of Mitochondrial RNA-processing Endoribonuclease via the Induction of miR-206/miR-1-3p Levels. HUVEC, RIPostC
50  2021 Extracellular Vesicle-Derived microRNA-410 From Mesenchymal Stem Cells Protects Against Neonatal Hypoxia-Ischemia Brain Damage Through an HDAC1-Dependent EGR2/Bcl2 Axis. Bcl2, EGR2, EVs, HDAC1, HIBD, HUC, miR, mNSS, MSCs
51  2021 Extracellular vesicles from skin precursor-derived Schwann cells promote axonal outgrowth and regeneration of motoneurons via Akt/mTOR/p70S6K pathway. EVs, PNI, SCI, SKP-SC-EVs, SKP-SCs
52  2021 Four new resorcinol derivatives with neuroprotective activities from Xylaria nigripes. ECD
53  2021 Foxo1-induced miR-92b down-regulation promotes blood-brain barrier damage after ischaemic stroke by targeting NOX4. BBB, BMECs, MCAO, NOX4
54  2021 GAS5 knockdown alleviates spinal cord injury by reducing VAV1 expression via RNA binding protein CELF2. CELF2, GAS5, GSH-Px, MDA, SCI, SOD, VAV1
55  2021 Geranylgeranylacetone ameliorated ischemia/reperfusion induced-blood brain barrier breakdown through HSP70-dependent anti-apoptosis effect. BBB, EB, GGA, HSP, I/R, qRT-PCR, TEER, TJPs, tMCAO
56  2021 Ginkgolide B Alleviates Learning and Memory Impairment in Rats With Vascular Dementia by Reducing Neuroinflammation via Regulating NF-κB Pathway. BCCAO, GB, MWM, NF-kappaB, SD, TLR4, VD
57  2021 Guhong Injection Protects Against Apoptosis in Cerebral Ischemia by Maintaining Cerebral Microvasculature and Mitochondrial Integrity Through the PI3K/AKT Pathway. Bcl-2, bFGF, cyt c, ELISA, GHI, LDH, MCAO, MDA, MMP-9, RBMECs, SOD, TGF-beta1, VEGF
58  2021 HDAC9 Silencing Exerts Neuroprotection Against Ischemic Brain Injury via miR-20a-Dependent Downregulation of NeuroD1. HDACs, MCAO, miR-20a, NeuroD1
59  2021 HDACi protects against vascular cognitive impairment from CCH injury via induction of BDNF-related AMPA receptor activation. BCCAO, CCH, HDACi, SAHA, sham
60  2021 Histone Demethylase KDM4A Inhibition Represses Neuroinflammation and Improves Functional Recovery in Ischemic Stroke. MCAO, VEGF
61  2021 Human umbilical cord mesenchymal stem cell-derived exosomal miR-146a-5p reduces microglial-mediated neuroinflammation via suppression of the IRAK1/TRAF6 signaling pathway after ischemic stroke. Exos, HUMSCs
62  2021 Huperzine A lowers intraocular pressure via the M3 mAChR and provides retinal neuroprotection via the M1 mAChR: a promising agent for the treatment of glaucoma. AChEI, AD, HupA, I/R, IOP, mAChR, PRNs
63  2021 Hypoxia preconditioning improves structure and function of astrocytes mitochondria via PGC-1α/HIF signal. HP, PGC-1alpha, UCP2
64  2021 Identification and Quantification of Glutathionylated Cysteines under Ischemic Stress. ---
65  2021 Improvement of sensory neuron growth and survival via negatively regulating PTEN by miR-21-5p-contained small extracellular vesicles from skin precursor-derived Schwann cells. DRGs, miR, PNI, SKP-SC-EVs, SKP-SCs
66  2021 In Vitro Model for Ischemic Stroke: Functional Analysis of Vascular Smooth Muscle Cells. IS, NVU, SMCs
67  2021 In vitro P38MAPK inhibition in aged astrocytes decreases reactive astrocytes, inflammation and increases nutritive capacity after oxygen-glucose deprivation. ---
68  2021 Inhibition of CAMK II modulates water permeability by reducing AQP4 expression in astrocytes after oxygen-glucose deprivation. AQP4, CaMKII, NMDARs
69  2021 Inhibition of Fatty Acid Synthesis Aggravates Brain Injury, Reduces Blood-Brain Barrier Integrity and Impairs Neurological Recovery in a Murine Stroke Model. BBB, FAS, TER
70  2021 Inhibition of microRNA-143-3p Attenuates Cerebral Ischemia/Reperfusion Injury by Targeting FSTL1. I/R, miRNA, TTC
71  2021 Inhibition of MLKL Attenuates Necroptotic Cell Death in a Murine Cell Model of Ischaemia Injury. AML12, FFA, I/R, MLKL, PTGS2, RIPK1, RIPK3, si
72  2021 Inhibition of PDE1-B by Vinpocetine Regulates Microglial Exosomes and Polarization Through Enhancing Autophagic Flux for Neuroprotection Against Ischemic Stroke. ---
73  2021 Inhibition of TLR4 prevents hippocampal hypoxic-ischemic injury by regulating ferroptosis in neonatal rats. HI, HIBD, TEM, TLR4
74  2021 Inhibitory Effect of Gualou Guizhi Decoction on Microglial Inflammation and Neuron Injury by Promoting Anti-Inflammation via Targeting mmu-miR-155. GLGZD, RT-PCR
75  2021 Knockdown of lncRNA SNHG15 Ameliorates Oxygen and Glucose Deprivation (OGD)-Induced Neuronal Injury via Regulating the miR-9-5p/TIPARP Axis. lncRNA, MCAO, SNHG15
76  2021 LncRNA MIAT knockdown alleviates oxygen-glucose deprivation‑induced cardiomyocyte injury by regulating JAK2/STAT3 pathway via miR-181a-5p. Bax, Bcl-2, CAD, HCM, I/R, IL, JAK2, MIAT, STAT3
77  2021 LncRNA NEAT1 Promote Inflammatory Responses in Coronary Slow Flow Through Regulating miR-148b-3p/ICAM-1 Axis. CCK-8, ceRNA, CSF, EdU, HUVECs, IL-6, lncRNAs, NEAT1, RIP, SAQ, sICAM-1, TNF-alpha
78  2021 LncRNA SERPINB9P1 expression and polymorphisms are associated with ischemic stroke in a Chinese Han population. IS, lncRNAs
79  2021 LncRNA Snhg8 attenuates microglial inflammation response and blood-brain barrier damage in ischemic stroke through regulating miR-425-5p mediated SIRT1/NF-κB signaling. BMEC, lncRNAs, MCAO, NF-kappaB, SIRT1, Snhg8
80  2021 LncRNA TCONS_00041002 improves neurological outcomes in neonatal rats with hypoxic-ischemic encephalopathy by inhibiting apoptosis and promoting neuron survival. GO, HIE, lncRNAs
81  2021 LncRNA XIST Promoted OGD-Induced Neuronal Injury Through Modulating/miR-455-3p/TIPARP Axis. Bcl-2, Cleaved-cas3
82  2021 Long non-coding RNA Gm11974 aggravates oxygen-glucose deprivation-induced injury via miR-122-5p/SEMA3A axis in ischaemic stroke. lncRNAs, MCAO, miR-122-5p, MTT, qRT-PCR, Sema3A
83  2021 Long non-coding RNA LOC366613 alleviates the cerebral ischemic injury via regulating the miR-532-5p/phosphatase and tensin homolog axis. CI, LDH, lncRNAs, MCAO, PTEN, TTC
84  2021 Long non-coding RNA RMST promotes oxygen-glucose deprivation-induced injury in brain microvascular endothelial cells by regulating miR-204-5p/VCAM1 axis. CCK-8, LDH, lncRNAs, qRT-PCR, RIP, RMST, VCAM-1, WB
85  2021 Long non-coding RNA ZFAS1 exerts a protective role to alleviate oxygen and glucose deprivation-mediated injury in ischemic stroke cell model through targeting miR-186-5p/MCL1 axis. 3'UTR, CCK-8, IS, lncRNAs, MCL-1, miR-186-5p, mRNA, qRT-PCR, RIP, ZFAS1
86  2021 Long Non-coding RNAMALAT1 Knockdown Alleviates Cerebral Ischemia/Reperfusion Injury of Rats Through Regulating the miR-375/PDE4D Axis. CI/RI, LDH, lncRNA, MALAT1, MCAO, ROS, SOD
87  2021 Long Noncoding RNA SNHG14 Promotes Ischemic Brain Injury via Regulating miR-199b/AQP4 Axis. AQP4, CCK-8, ELISA, lncRNAs, MCAO, miR-199b, qRT-PCR, SNHG14
88  2021 Long Noncoding RNA X-Inactive Specific Transcript Regulates Neuronal Cell Apoptosis in Ischemic Stroke Through miR-98/BACH1 Axis. XIST
89  2021 Lycopene Exerts Neuroprotective Effects After Hypoxic-Ischemic Brain Injury in Neonatal Rats via the Nuclear Factor Erythroid-2 Related Factor 2/Nuclear Factor-κ-Gene Binding Pathway. HI, HIE, LYC
90  2021 Lycopene prevents oxygen-glucose deprivation-induced autophagic death in SH-SY5Y cells via inhibition of the oxidative stress-activated AMPK/mTOR pathway. ATG5, LDH
91  2021 Lysosomal calcium is modulated by STIM1/TRPML1 interaction which participates to neuronal survival during ischemic preconditioning. ER, IPC, ROS, STIM1
92  2021 Mangiferin prevents myocardial infarction-induced apoptosis and heart failure in mice by activating the Sirt1/FoxO3a pathway. MI
93  2021 Maternally expressed 3 protects the intestinal barrier from cardiac arrest-induced ischemia/reperfusion injury via miR-34a-3p/sirtuin 1/nuclear factor kappa B signaling. CA, CLDN1, ELISA, I/R, IFN, IL, lncRNAs, MTT, NF-kappaB, qPCR, SD, SIRT1, TEER, TGFB, TNF, TUNEL
94  2021 Mechanism of ARPP21 antagonistic intron miR-128 on neurological function repair after stroke. MCAO
95  2021 Medioresinol as a novel PGC-1α activator prevents pyroptosis of endothelial cells in ischemic stroke through PPARα-GOT1 axis. BBB, BMVECs, MDN, mtROS, tMCAO
96  2021 Melatonin Protects Against Ischemic Brain Injury by Modulating PI3K/AKT Signaling Pathway via Suppression of PTEN Activity. dMCAO, N2a
97  2021 Mesenchymal stem cell-derived exosome miR-542-3p suppresses inflammation and prevents cerebral infarction. MCAO, MSCs, TLR4
98  2021 Microglia exosomal miRNA-137 attenuates ischemic brain injury through targeting Notch1. tMCAO
99  2021 MicroRNA-26b-5p alleviates cerebral ischemia-reperfusion injury in rats via inhibiting the N-myc/PTEN axis by downregulating KLF10 expression. CIR
100  2021 MicroRNA-410 serves as a candidate biomarker in hypoxic-ischemic encephalopathy newborns and provides neuroprotection in oxygen-glucose deprivation-injured PC12 and SH-SY5Y cells. HIE, miR-410, PTEN