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Abbreviation : OX1R
Long Form : orexin receptor type 1
No. Year Title Co-occurring Abbreviation
2021 Identification and Characterization of Cannabidiol as an OX1R Antagonist by Computational and In Vitro Functional Validation. CBD
2021 Induction of narcolepsy-like symptoms by orexin receptor antagonists in mice. NREM, REM, SOREM
2021 Orexin 1 and 2 Receptors in the Prelimbic Cortex Modulate Threat Valuation. mPFC, PL
2021 Wakefulness-Promoting Effects of Lateral Hypothalamic Area-Deep Brain Stimulation in Traumatic Brain Injury-Induced Comatose Rats: Upregulation of α1-Adrenoceptor Subtypes and Downregulation of Gamma-Aminobutyric Acid β Receptor Expression Via the Orexins Pathway. alpha1-AR, DBS, GABABR, LHA-DBS, TBIs
2019 Orexin-A Excites Airway Vagal Preganglionic Neurons via Activation of Orexin Receptor Type 1 and Type 2 in Rats. AVPNs, IA-AVPNs
2018 In vitro, in vivo and ex vivo demonstration of the antitumoral role of hypocretin-1/orexin-A and almorexant in pancreatic ductal adenocarcinoma. PDAC
2018 The Orexin/Receptor System: Molecular Mechanism and Therapeutic Potential for Neurological Diseases. AD, GPCRs, LH
2018 Wake-promoting effects of vagus nerve stimulation after traumatic brain injury: upregulation of orexin-A and orexin receptor type 1 expression in the prefrontal cortex. ---
2018 [Chronic alcoholism influences the mRNA level of the orexin receptor type 1 (OX1R) in emotiogenic structures of the rat brain]. ---
10  2015 Effect of short and long-term treatment with antipsychotics on orexigenic/anorexigenic neuropeptides expression in the rat hypothalamus. MC4R, NPY, NUCB2, POMC, ppOX
11  2012 Expression of orexin receptors in the pituitary. ---
12  2010 Central orexin-A increases gastric motility in rats. ARS, CRF, DMV, i.c.v, OXA
13  2010 Endogenous orexin-A modulates gastric motility by peripheral mechanisms in rats. OXA, PPO
14  2006 Agonist potency differentiates G protein activation and Ca2+ signalling by the orexin receptor type 1. ---
15  2003 Effects of orexin (hypocretin) on GIRK channels. GTP, LC, PTX, TM
16  2003 Orexin receptor type-1 couples exclusively to pertussis toxin-insensitive G-proteins, while orexin receptor type-2 couples to both pertussis toxin-sensitive and -insensitive G-proteins. cAMP, OX2R, PLC, PTX