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Abbreviation : PEITC
Long Form : phenethyl isothiocyanate
No. Year Title Co-occurring Abbreviation
2022 Characterization of the Inclusion Complexes of Isothiocyanates with γ-Cyclodextrin for Improvement of Antibacterial Activities against Staphylococcus aureus. BITC, gamma-CD, ITCs, MTPITC, qRT-PCR, S. aureus, SEM
2022 Direct Inhibition of GSDMD by PEITC Reduces Hepatocyte Pyroptosis and Alleviates Acute Liver Injury in Mice. ALI, AST, Con A, GSDMD, IFN, LDH, NLRP3, TNF
2022 Evaluation of Bioactive Properties of Lipophilic Fractions of Edible and Non-Edible Parts of Nasturtium officinale (Watercress) in a Model of Human Malignant Melanoma Cells. ---
2022 Phenethyl isothiocyanate as an anti-nutritional factor attenuates deoxynivalenol-induced IPEC-J2 cell injury through inhibiting ROS-mediated autophagy. ATG5, CAT, COX-2, DON, GFP-LC3, GPX1, HO-1, iNOS, p-AKT, p-mTOR, PI3K, ROS, SOD2, ZO-1
2022 Phenethyl Isothiocyanate Enhances the Cytotoxic Effects of PARP Inhibitors in High-Grade Serous Ovarian Cancer Cells. HGSOC, PARPi
2022 Phenethyl Isothiocyanate Suppresses the Proinflammatory Cytokines in Human Glioblastoma Cells through the PI3K/Akt/NF-κB Signaling Pathway In Vitro. Akt, ELISA, EMSA, ERK, GBM, IL-1beta, IL-6, PCR, PI3K, RTK, TNF-alpha
2022 Phenethylisothiocyanate Potentiates Platinum Therapy by Reversing Cisplatin Resistance in Cervical Cancer. ---
2022 Phenylethyl Isothiocyanate: A Bioactive Agent for Gastrointestinal Health. ---
2022 Tumor-targeted hyaluronic acid-based oxidative stress nanoamplifier with ROS generation and GSH depletion for antitumor therapy. CA, EPR, HA-CA
10  2021 A Method for Liposome Co-encapsulation of Phenethyl Isothiocyanate and Cisplatin and Determining Its Toxicity Against Lung and Lung Cancer Cells. NSCLC
11  2021 Antiproliferative Wnt inhibitor wogonin prevents eryptosis following ionophoric challenge, hyperosmotic shock, oxidative stress, and metabolic deprivation. PS, RBCs, WGN
12  2021 Cancer-preventive effect of phenethyl isothiocyanate through tumor microenvironment regulation in a colorectal cancer stem cell xenograft model. CSCs
13  2021 Chemopreventive Effects of Dietary Isothiocyanates in Animal Models of Gastric Cancer and Synergistic Anticancer Effects With Cisplatin in Human Gastric Cancer Cells. ITCs, MNU
14  2021 Chitosan-olive oil microparticles for phenylethyl isothiocyanate delivery: Optimal formulation. ---
15  2021 Combinations of Phytochemicals More Efficiently than Single Components Activate Nrf2 and Induce the Expression of Antioxidant Enzymes in Pancreatic Cancer Cells. I3C, RES, XAN
16  2021 Comparison of the Impact of Xanthohumol and Phenethyl Isothiocyanate and Their Combination on Nrf2 and NF-kappaB Pathways in HepG2 Cells In Vitro and Tumor Burden In Vivo. I3C, RES
17  2021 Detoxification of heterocyclic aromatic amines from grilled meat using a PEITC-rich vegetable sauce: a randomized crossover controlled trial. HAAs
18  2021 Dietary glucosinolates inhibit splenic inflammation in high fat/cholesterol diet-fed C57BL/6 mice. COX-2, DIM, HFCD, IL-6, NF-kappaB, TLR
19  2021 Dietary Isothiocyanates, Sulforaphane and 2-Phenethyl Isothiocyanate, Effectively Impair Vibrio cholerae Virulence. ITC, MBC, MIC, SFN
20  2021 DNA methylome, transcriptome, and prostate cancer prevention by phenethyl isothiocyanate in TRAMP mice. PCa
21  2021 Lactate dehydrogenases amplify reactive oxygen species in cancer cells in response to oxidative stimuli. PL
22  2021 Nontoxic dose of Phenethyl isothiocyanate ameliorates deoxynivalenol-induced cytotoxicity and inflammation in IPEC-J2 cells. DON, GSLs
23  2021 PEITC inhibits the invasion and migration of colorectal cancer cells by blocking TGF-beta-induced EMT. CRC, EMT
24  2021 Phenethyl isothiocyanate attenuates diabetic nephropathy via modulation of glycative/oxidative/inflammatory signaling in diabetic rats. AGEs, DN, gamma-GCS, GLO1, HO-1, Nrf2
25  2021 Phenethyl Isothiocyanate Improves Lipid Metabolism and Inflammation via mTOR/PPARgamma/AMPK Signaling in the Adipose Tissue of Obese Mice. AMPK, COX-2, LOX-1, mTOR, NF-kappaB, PPARgamma, qPCR
26  2021 Phenethyl isothiocyanate reduces breast cancer stem cell-like properties by epigenetic reactivation of CDH1. BCSCs, CDH1
27  2021 Phenethyl Isothiocyanate-Containing Carbomer Gel for Use against Squamous Cell Carcinoma. 5-FU, SCC
28  2021 Preparation of a Beverage Containing Freeze-Dried Watercress for a Clinical Trial of Carcinogen and Toxicant Detoxification. ---
29  2021 Protective effects of phenethyl isothiocyanate on foam cell formation by combined treatment of oxidized low-density lipoprotein and lipopolysaccharide in THP-1 macrophage. ABCA1, CD36, LOX-1, LPS, LXRalpha, NF-kappaB, ox-LDL, PPARgamma, SIRT1, SR-A1
30  2021 Type 2 diabetes mellitus potentiates acute acrylonitrile toxicity: Potentiation reduction by phenethyl isothiocyanate. AN, CcO, CYP2E1, ROS
31  2020 Anti-rheumatic activity of Phenethyl isothiocyanate via inhibition of histone deacetylase-1. CFA, HDAC1, RA
32  2020 beta-Phenethyl Isothiocyanate Induces Cell Death in Human Osteosarcoma through Altering Iron Metabolism, Disturbing the Redox Balance, and Activating the MAPK Signaling Pathway. ---
33  2020 Characterisation of naturally occurring isothiocyanates as glutathione reductase inhibitors. BITC, GR, hGR, yGR
34  2020 Combination of xanthohumol and phenethyl isothiocyanate inhibits NF-kappaB and activates Nrf2 in pancreatic cancer cells. I3C, PC, RES, XAN
35  2020 Development of human prostate cancer stem cells involves epigenomic alteration and PI3K/AKT pathway activation. PI3K
36  2020 Dynamic biospeckle analysis, a new tool for the fast screening of plant nematicide selectivity. ---
37  2020 Naringin in Combination with Isothiocyanates as Liposomal Formulations Potentiates the Anti-inflammatory Activity in Different Acute and Chronic Animal Models of Rheumatoid Arthritis. CLFs, FCA, NAR, SFN
38  2020 Neuroprotective potential of isothiocyanates in an in vitro model of neuroinflammation. AITC, ERK, ITCs, MAPK, MMP, SFN
39  2020 PEITC triggers multiple forms of cell death by GSH-iron-ROS regulation in K7M2 murine osteosarcoma cells. ROS
40  2020 Phenethyl Isothiocyanate Protects against High Fat/Cholesterol Diet-Induced Obesity and Atherosclerosis in C57BL/6 Mice. ABCA1, CD36, CON, LXRalpha, NF-kappaB, PPARgamma
41  2020 Phenethyl Isothiocyanate Suppresses Stemness in the Chemo- and Radio-Resistant Triple-Negative Breast Cancer Cell Line MDA-MB-231/IR Via Downregulation of Metadherin. CSCs, MTDH, ROS, TNBC
42  2020 Phenethyl isothiocyanate synergistically induces apoptosis with Gefitinib in non-small cell lung cancer cells via endoplasmic reticulum stress-mediated degradation of Mcl-1. ER stress, ITCs, Mcl-1, NSCLC, PERK
43  2020 Phenylethyl Isothiocyanate Extracted from Watercress By-Products with Aqueous Micellar Systems: Development and Optimisation. AMSs, ORAC
44  2020 Stomatal response to isothiocyanates in Arabidopsis thaliana. AITC, BITC, ITCs, ROS, SFN
45  2020 The effect of benzyl isothiocyanate on Candida albicans growth, cell size, morphogenesis, and ultrastructure. AITC, BITC, DD, GTF, ITCs
46  2019 Benzyl Isothiocyanate and Phenethyl Isothiocyanate Inhibit Adipogenesis and Hepatosteatosis in Mice with Obesity Induced by a High-Fat Diet. BITC, HFD, LFD
47  2019 Comparing the protective effects of three sulfur compounds against acrylonitrile-induced acute toxicity in CYP2E1-induced rats. ACN, CcOX, CYP2E1, DMTS, i.g, i.p, MDA, STS
48  2019 Comparison of Pregnane X Receptor Antagonists for Enhancing the Antitumor Effect of Cisplatin. ABCC2, PXR
49  2019 Cooking has the potential to decrease the antitumor effect of fresh Betong watercress. CF, CMRs
50  2019 Drug-binding albumins forming stabilized nanoparticles for efficient anticancer therapy. BSA-ITCs, PTX
51  2019 Effects of 2-Phenethyl Isothiocyanate on Metabolism of 1,3-Butadiene in Smokers. ---
52  2019 Glucosinolate-Degradation Products as Co-Adjuvant Therapy on Prostate Cancer in Vitro. 4PI, AIPC, AITC, DOCE, GS-degradation products, I3C, IB, SFN
53  2019 NRF2-Independent Regulation of Intestinal Constitutive Androstane Receptor by the Pro-Oxidants Cadmium and Isothiocyanate in hUGT1 Mice. CAR, ITC, Nrf2, ROS
54  2019 Nuclear Nrf2 Activity in Laryngeal Carcinoma is Regulated by SENP3 After Cisplatin-Induced Reactive Oxygen Species Stress. 5-FU, NAC, Nrf2, ROS, SENP3, SUMO
55  2019 p53 mutant-type in human prostate cancer cells determines the sensitivity to phenethyl isothiocyanate induced growth inhibition. GOF
56  2019 Phenethyl Isothiocyanate and Cisplatin Co-Encapsulated in a Liposomal Nanoparticle for Treatment of Non-Small Cell Lung Cancer. NSCLC
57  2019 Phenethyl Isothiocyanate Exposure Promotes Oxidative Stress and Suppresses Sp1 Transcription Factor in Cancer Stem Cells. ALDH1, CSCs, hCSCs, ROS
58  2019 Phenethyl isothiocyanate hampers growth and progression of HER2-positive breast and ovarian carcinoma by targeting their stem cell compartment. ALDH, CSCs, SFE, WTHER2
59  2019 Phenethyl isothiocyanate induces IPEC-J2 cells cytotoxicity and apoptosis via S-G2/M phase arrest and mitochondria-mediated Bax/Bcl-2 pathway. GLS
60  2019 Phenethyl isothiocyanate stimulates glucose uptake through the Akt pathway in C2C12 myotubes. GLUT4
61  2019 Phenylethyl isothiocyanate induces oxidative damage of porcine kidney cells mediated by reactive oxygen species. ROS
62  2019 Potent antitumor activity of Laccaic acid and Phenethyl isothiocyanate combination in colorectal cancer via dual inhibition of DNA methyltransferase-1 and Histone deacetylase-1. CRC, LA
63  2019 Sequential treatment of phenethyl isothiocyanate increases sensitivity of Temozolomide resistant glioblastoma cells by decreasing expression of MGMT via NF-kappaB pathway. GBM, TMD
64  2019 Susceptibility to the acute toxicity of acrylonitrile in streptozotocin-induced diabetic rats: protective effect of phenethyl isothiocyanate, a phytochemical CYP2E1 inhibitor. AN, CYP2E1, GST, STZ
65  2019 The structure of Trametes versicolor glutathione transferase Omega 3S bound to its conjugation product glutathionyl-phenethylthiocarbamate reveals plasticity of its active site. G site, H-site, ITC, TvGSTO3S
66  2019 Various modes of action of dietary phytochemicals, sulforaphane and phenethyl isothiocyanate, on pathogenic bacteria. ITCs, SFN
67  2018 Anti-Carcinogenic Glucosinolates in Cruciferous Vegetables and Their Antagonistic Effects on Prevention of Cancers. ARE, BITC, GSL, ITCs, NF-kappaB, Nrf2, ROS
68  2018 BAG3 Protein Is Involved in Endothelial Cell Response to Phenethyl Isothiocyanate. HSP, HUVECs, JNK
69  2018 Designing of the Anticancer Nanocomposite with Sustained Release Properties by Using Graphene Oxide Nanocarrier with Phenethyl Isothiocyanate as Anticancer Agent. GO, PBS
70  2018 Histone Methyltransferase Setd7 Regulates Nrf2 Signaling Pathway by Phenethyl Isothiocyanate and Ursolic Acid in Human Prostate Cancer Cells. ARE, ChIP, Gstt2, NQO1, PCa, ROS, Setd7, UA
71  2018 Impact of Nrf2 on tumour growth and drug sensitivity in oncogenic K-ras-transformed cells in vitro and in vivo. HO-1, NQO1, ROS
72  2018 Inhibition of Glycolysis in Prostate Cancer Chemoprevention by Phenethyl Isothiocyanate. PrSC, TRAMP
73  2018 Isothiocyanates: Translating the Power of Plants to People. SFN
74  2018 Metabolic targets of watercress and PEITC in MCF-7 and MCF-10A cells explain differential sensitisation responses to ionising radiation. IR
75  2018 PEITC promotes neurite growth in primary sensory neurons via the miR-17-5p/STAT3/GAP-43 axis. ---
76  2018 Phenethyl isothiocyanate activates leptin signaling and decreases food intake. PTP1B
77  2018 Phenethyl isothiocyanate in combination with dibenzoylmethane inhibits the androgen-independent growth of prostate cancer cells. DBM, NF-kappaB, p-Akt, SCID
78  2018 Phenethyl Isothiocyanate Induces Apoptotic Cell Death Through the Mitochondria-dependent Pathway in Gefitinib-resistant NCI-H460 Human Lung Cancer Cells In Vitro. ROS
79  2018 Phenethyl isothiocyanate inhibits colorectal cancer stem cells by suppressing Wnt/beta-catenin pathway. CSCs
80  2018 Phenethyl Isothiocyanate Inhibits In Vivo Growth of Xenograft Tumors of Human Glioblastoma Cells. DMSO, Mcl-1, XIAP
81  2018 Phenethyl isothiocyanate Triggers Apoptosis, Combats Oxidative Stress and Inhibits Growth of Ehrlich Ascites Carcinoma Mouse Model. DOX, EAC, MDA, TAC
82  2018 Phenethyl Isothiocyanate, a Dual Activator of Transcription Factors NRF2 and HSF1. HSF1, ITCs, Nrf2
83  2018 Protective Effect of Glucosinolates Hydrolytic Products in Neurodegenerative Diseases (NDDs). ER, GLS, ITCs, MG, NDDs, SFN
84  2018 Sensory acceptable equivalent doses of beta-phenylethyl isothiocyanate (PEITC) induce cell cycle arrest and retard the growth of p53 mutated oral cancer in vitro and in vivo. ---
85  2018 Suppression of glutathione S-transferases potentiates the cytotoxic effect of phenethyl isothiocyanate in cholangiocarcinoma cells. CCA, EA, GST
86  2018 Synthesis and evaluation of a paclitaxel-binding polymeric micelle for efficient breast cancer therapy. PTX
87  2018 TH588, an MTH1 inhibitor, enhances phenethyl isothiocyanate-induced growth inhibition in pancreatic cancer cells. ROS
88  2018 The oxidoreductase p66Shc acts as tumor suppressor in BRAFV600E-transformed cells. ROS
89  2018 Transcriptomic Analysis of Histone Methyltransferase Setd7 Knockdown and Phenethyl Isothiocyanate in Human Prostate Cancer Cells. IPA, KD, PCa
90  2017 Benzyl isothiocyanate and phenethyl isothiocyanate inhibit murine melanoma B16F10 cell migration and invasion in vitro. BITC, MMP-2, TIMP
91  2017 Benzyl isothiocyanate induces protective autophagy in human lung cancer cells through an endoplasmic reticulum stress-mediated mechanism. AITC, AVOs, BITC, SFN
92  2017 Dietary Phenethyl Isothiocyanate Protects Mice from Colitis Associated Colon Cancer. DSS
93  2017 Dietary phytochemical PEITC restricts tumor development via modulation of epigenetic writers and erasers. HDACs, PcG
94  2017 Effect of isothiocyanates, BITC and PEITC, on stress protein accumulation, protein aggregation and aggresome-like structure formation in Xenopus A6 kidney epithelial cells. BITC, HO-1, HSPs, ITCs
95  2017 Fatty Acid Synthesis Intermediates Represent Novel Noninvasive Biomarkers of Prostate Cancer Chemoprevention by Phenethyl Isothiocyanate. ACC1, CPT1A, FASN, TRAMP
96  2017 Identification of deubiquitinase targets of isothiocyanates using SILAC-assisted quantitative mass spectrometry. DUBs, ITCs
97  2017 Inhibition of autophagy potentiates the anti-metastasis effect of phenethyl isothiocyanate through JAK2/STAT3 pathway in lung cancer cells. AVOs, BITC, CQ
98  2017 Inhibition of cancer growth in vitro and in vivo by a novel ROS-modulating agent with ability to eliminate stem-like cancer cells. ROS, SP
99  2017 Isothiocyanates induce UGT1A1 in humanized UGT1 mice in a CAR dependent fashion that is highly dependent upon oxidative stress. AREs, hUGT1, ROS, TSB, UGTs
100  2017 Isothiocyanates suppress the invasion and metastasis of tumors by targeting FAK/MMP-9 activity. BITC, SFN, TPA