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Abbreviation : PHLDA2
Long Form : pleckstrin homology-like domain, family A, member 2
No. Year Title Co-occurring Abbreviation
2022 Knockdown of PHLDA2 promotes apoptosis and autophagy of glioma cells through the AKT/mTOR pathway. ---
2022 RhoGDI1 interacts with PHLDA2, suppresses the proliferation, migration, and invasion of trophoblast cells, and participates in the pathogenesis of preeclampsia. Co-IP, PE, RhoGDI
2021 HGF-mediated Up-regulation of PHLDA2 Is Associated With Apoptosis in Gastric Cancer. shRNA
2020 Combined Use of Three Machine Learning Modeling Methods to Develop a Ten-Gene Signature for the Diagnosis of Ventilator-Associated Pneumonia. Arg1, AUC, CFD, DEGs, DUSP2, GEO, GO, Hp, IL18R1, KEGG, LAMB3, LASSO, MLP, MMP8, NAIP, PLAU, ROC, VAP
2020 Inhibition of PHLDA2 transcription by DNA methylation and YY1 in goat placenta. HDAC1, YY1
2020 PHLDA2 gene polymorphisms and risk of HELLP syndrome and severe preeclampsia. PE
2020 PHLDA2 regulates EMT and autophagy in colorectal cancer via the PI3K/AKT signaling pathway. EMT
2019 Upregulation of miR-214 Induced Radioresistance of Osteosarcoma by Targeting PHLDA2 via PI3K/Akt Signaling. UTR
2017 Nuclear transfer alters placental gene expression and associated histone modifications of the placental-specific imprinted gene pleckstrin homology-like domain, family A, member 2 (PHLDA2) in cattle. ChIP, HAND1, NT, PAG-9, PL
10  2016 Lentivirus-mediated PHLDA2 overexpression inhibits trophoblast proliferation, migration and invasion, and induces apoptosis. CCK-8, CK18, hPL, PI, ROS
11  2016 Maternal prenatal depression is associated with decreased placental expression of the imprinted gene PEG3. CDKN1C, hPL, MBAM, PEG10, PEG3
12  2015 PHLDA2 is a key oncogene-induced negative feedback inhibitor of EGFR/ErbB2 signaling via interference with AKT signaling. ---
13  2015 Placental expression of the insulin receptor binding protein GRB10: Relation to human fetoplacental growth and fetal gender. Grb10
14  2015 The expression of the imprinted gene pleckstrin homology-like domain family A member 2 in placental tissues of preeclampsia and its effects on the proliferation, migration and invasion of trophoblast cells JEG-3. DBP, PE, SBP
15  2015 The role and interaction of imprinted genes in human fetal growth. CVS, DLK1, Grb10, IGF2, SNP
16  2015 [Placental PHLDA2 gene imprinting in patients with pre-eclampsia]. LOI, PHLDA2-2, SNPs
17  2014 Altered gene expression in human placentas after IVF/ICSI. CDKN1C, IGF2, LOI, MEST, NTR, SDHA, TBP
18  2014 Hypoxia influences expression profile of Pleckstrin homology-like domain, family A, member 2 in Indian catfish, Clarias batrachus (Linnaeus, 1758): a new candidate gene for hypoxia tolerance in fish. ---
19  2014 Isolating the role of elevated Phlda2 in asymmetric late fetal growth restriction in mice. BL6
20  2012 Epigenetic state and expression of imprinted genes in umbilical cord correlates with growth parameters in human pregnancy. BW, PEG10
21  2006 Elevated placental expression of the imprinted PHLDA2 gene is associated with low birth weight. IGF2, IGF2R