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Abbreviation : PR3
Long Form : proteinase 3
No. Year Title Co-occurring Abbreviation
2021 Activity-Based Probes to Utilize the Proteolytic Activity of Cathepsin G in Biological Samples. ABPs, CatG, CyTOF, NSP4
2021 Advances in the genomics of ANCA-associated vasculitis-a view from East Asia. AAV, ANCA, GWAS, MPA, MPO
2021 Altered circulating CCR6+and CXCR3+ T cell subsets are associated with poor renal prognosis in MPO-ANCA-associated vasculitis. AAV, MPO, PBMCs
2021 ANCA Status or Clinical Phenotype - What Counts More? ANCA, GPA, MPA, MPO
2021 ANCA-Associated Vasculitis: An Update. ANCA, EGPA, GPA, MPA, MPO
2021 Angiopoietin 1 release from human neutrophils is independent from neutrophil extracellular traps (NETs). Ang-1, HC, HF, HFpEF, MPO, NE, NETs
2021 Antibody subtypes and titers predict clinical outcomes in ANCA-associated vasculitis. AAV, ANCA, ESRD, MPO
2021 Antineutrophil cytoplasmic antibodies (ANCA) - their role in pathogenesis, diagnosis, and treatment monitoring of ANCA-associated vasculitis. ANCA, MPO, NETs
2021 Antineutrophil cytoplasmic antibody (ANCA) vasculitis: pathophysiology, diagnosis, and the evolving treatment landscape. ANCA, C5a, CD
10  2021 Autoantibodies Against Lysosome Associated Membrane Protein-2 (LAMP-2) in Pediatric Chronic Primary Systemic Vasculitis. ANCA, CRP, ESR, GFR, LAMP-2, MPO, pVAS
11  2021 Cathepsin C promotes breast cancer lung metastasis by modulating neutrophil infiltration and neutrophil extracellular trap formation. CTSC, IL-1beta, NETs
12  2021 Characterization of CD177-reactive iso- and auto-antibodies. MoAb
13  2021 Complement Components C3 and C4 Indicate Vasculitis Manifestations to Distinct Renal Compartments in ANCA-Associated Glomerulonephritis. AAV, AKI, ANCA, CKD, ESRD, GN, MPO
14  2021 Differences between myeloperoxidase-antineutrophil cytoplasmic autoantibody (ANCA) and proteinase 3-ANCA associated vasculitis: A retrospective study from a single center in China. ANCA, ANCA, MPO
15  2021 Dynamic Changes in the Nasal Microbiome Associated With Disease Activity in Patients With Granulomatosis With Polyangiitis. ANCA, GPA
16  2021 Elevated Biomarkers of NETosis in the Serum of Pediatric Patients With Type 1 Diabetes and Their First-Degree Relatives. MPO, NE, NETs, PAD4, T1D
17  2021 Granulomatous Inflammation in ANCA-Associated Vasculitis. AAV, DAMP, EGPA, GPA, MPA, MPO
18  2021 Immunohistochemical characterization of granulomatosis with polyangiitis exhibiting spontaneous regression. GPA, TBLB
19  2021 Isotretinoin induced small vessel vasculitis: a life-threatening pulmonary-renal syndrome-a case report. ANCA, DV
20  2021 Lack of elevated pre-ART elastase-ANCA levels in patients developing TB-IRIS. ANCAs, ART, MPO, TB-IRIS
21  2021 Long-term validation of the renal risk score for vasculitis in a Southern European population. ANCA, CI, ESRD, HR, MPO
22  2021 Lupus nephritis and ANCA-associated vasculitis: towards precision medicine? AAV, ANCA, LN
23  2021 Neutrophil Elastase and Proteinase 3 Cleavage Sites Are Adjacent to the Polybasic Sequence within the Proteolytic Sensitive Activation Loop of the SARS-CoV-2 Spike Protein. CatG, NE, NSP4, S protein
24  2021 Prevalence and risk factors of relapse in patients with ANCA-associated vasculitis receiving cyclophosphamide induction: a systematic review and meta-analysis of large observational studies. AAV, aHRs, CIs, CRRs
25  2021 Proliferative glomerulonephritis and mantle cell lymphoma: a rare association. ANCA, MCL
26  2021 Protease-Specific Biomarkers to Analyse Protease Inhibitors for Emphysema Associated with Alpha 1-Antitrypsin Deficiency. An Overview of Current Approaches. AAT, AATD, COPD, NE
27  2021 Proteinase 3 contributes to endothelial dysfunction in an experimental model of sepsis. CORM-3, HLE, HUVECs, PMNs
28  2021 Pyoderma gangrenosum-like ulceration as a presenting feature of pediatric granulomatosis with polyangiitis. GPA, PG
29  2021 The biology, pathogenetic role, clinical implications, and open issues of serum anti-neutrophil cytoplasmic antibodies. AAV, ANCA, MPO
30  2021 The Course of AαVal541 as a Proteinase 3 Specific Neo-Epitope after Alpha-1-Antitrypsin Augmentation in Severe Deficient Patients. AATD
31  2021 The relationship of neutrophil elastase and proteinase 3 with risk factors, and chronic complications in type 2 diabetes: A Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) sub-study. FIELD, NE, T2DM
32  2021 What is the meaning of ANCA positivity in IgG4-related disease? ANCA, IgG4-RD, IIF, P-ANCA
33  2021 [Serpins as important protective factors in the pathogenesis of acute lung injury/acute respiratory distress syndrome]. ALI/ARDS, CG, NE, NSP4, NSPs, SIRS, SP-D
34  2020 4C3 Human Monoclonal Antibody: A Proof of Concept for Non-pathogenic Proteinase 3 Anti-neutrophil Cytoplasmic Antibodies in Granulomatosis With Polyangiitis. ANCA, GPA, mAb
35  2020 A Case of Diffuse Alveolar Hemorrhage Associated with High-Titer of MPO-ANCA Demonstrating Cytoplasmic Staining Pattern. AAV, DAH, IIF, MPO
36  2020 An unusual presentation of propylthiouracil-induced anti-MPO and PR3 positive ANCA vasculitis with associated anti-GBM antibodies, IgA nephropathy and an IgG4 interstitial infiltrate: a case report. AAV, ANCA, GBM, MPO, PTU
37  2020 Anti-neutrophil cytoplasmic antibodies (ANCA): Antigen interactions and downstream effects. ANCA, MPO
38  2020 Anti-neutrophil cytoplasmic antibodies predate symptom onset of ANCA-associated vasculitis. A case-control study. AAV, ANCA, MPO
39  2020 Antineutrophil Cytoplasmic Antibody in Lupus Nephritis: Correlation with Clinicopathological Characteristics and Disease Activity. ANCA, anti-GBM autoAb, LN, MPO, SLE, SLEDAI
40  2020 Association of Cigarette Smoking With Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. ANCA, CIs, MPO, OR
41  2020 Cerebrospinal fluid biomarkers implicated in the pathogenesis of anti-neutrophil cytoplasmic antibody-related hypertrophic pachymeningitis. ANCA, ANCA-HP, BAFF, CSF, HP, MPO, MS, NIND, TGF-beta1
42  2020 Characteristics and prognosis of ANCA-positive retroperitoneal fibrosis: A systematic literature review. ANCA, MPO, RPF
43  2020 Clinical characteristics, the diagnostic criteria and management recommendation of otitis media with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (OMAAV) proposed by Japan Otological Society. ANCA, EGPA, GPA, JOS, MPA, MPO, OMAAV
44  2020 Concerted actions by MMPs, ADAMTS and serine proteases during remodeling of the cartilage callus into bone during osseointegration of hip implants. NE, OA, SLPI, TIMP
45  2020 Current Understanding and Unknown Aspects of the Treatment of Granulomatosis with Polyangiitis (Wegener's Granulomatosis): Opportunities for Future Studies. ANCA, CYP, GPA, IVIG, RTX
46  2020 Dissociation between airway and systemic autoantibody responses in chronic obstructive pulmonary disease. COPD, CTD-ILD, MPO, Sm, TPO, U1 snRNP
47  2020 Distinct HLA and non-HLA associations in different subtypes of ANCA-associated vasculitides in North India. AAV, CTLA-4, GPA, HLA, PCR-SSP, PTPN22
48  2020 Galectin-1 Facilitates Macrophage Reprogramming and Resolution of Inflammation Through IFN-beta. Gal-1, IFN-beta, IL-10, IL-12
49  2020 Human proteinase 3 resistance to inhibition extends to alpha-2 macroglobulin. 39pep-alpha2-M, alpha 2M, alpha1-PI, CatG, HNE, MNEI, NE
50  2020 Immunopathogenesis of ANCA-Associated Vasculitis. ANCA, EGPA, GPA, MPA, MPO
51  2020 Incidence and Risk Factors of Venous Thromboembolic Events in Patients with ANCA-Glomerulonephritis: A Cohort Study from the Maine-Anjou Registry. AAV, ANCA, VTE
52  2020 Membranous Nephropathy with Proteinase 3-ANCA-associated Vasculitis Successfully Treated with Rituximab. ANCA, ANCA-GN, MN
53  2020 Pathogenesis of ANCA-associated vasculitis: an emerging role for immunometabolism. AAV, ANCA, MPO
54  2020 Perspectives on signaling for biological- and processed food-related advanced glycation end-products and its role in cancer progression. AGEs, RAGE, Rb
55  2020 PR3 levels are impaired in plasma and PBMCs from Arabs with cardiovascular diseases. ANX3, CVD, MMP-9, PBMCs
56  2020 PR3-ANCAs predict relapses in ANCA-associated vasculitis patients after rituximab. ANCA, MPO, RI, RTX
57  2020 Proteinase 3 Autoreactivity in Anti-Neutrophil Cytoplasmic Antibody-associated vasculitis-Immunological versus clinical features. AAV, ANCA, MPO
58  2020 Simultaneous presentation of granulomatosis with polyangiitis (GPA) and immunoglobulin G4-related disease (IgG4-RD). Leaving an open question: widening the spectrum of a single disease or real overlap? ANCA, GPA, IgG4-RD, IgG4-RD
59  2020 Subcutaneous Immunoglobulin for Antibody Deficiency in Antineutrophil Cytoplasmic Antibody (ANCA)-associated Vasculitis. ANCA, CYC, HG, IVIG, RTX, SCIG
60  2020 The performance of the chemiluminescent immunoassay for measuring serum myeloperoxidase and proteinase 3 antibodies. ANCA, AUC, CIA, ELISA, GPA, HC group, IC group, MPA, MPO, ROC
61  2020 The search for the Holy Grail: autoantigenic targets in primary sclerosing cholangitis associated with disease phenotype and neoplasia. ANCA, autoAbs, GP2, IBD, PSC
62  2020 WT1, PRAME, and PR3 mRNA Expression in Acute Myeloid Leukemia (AML). AML, PRAME, TAAs
63  2020 [ANCA diagnostics in vasculitis]. AAV, ANCA, MPO
64  2020 [Value of anti-neutrophil cytoplasmic antibody in assessing the severity of bronchiolitis obliterans in children]. ANCA, BO, HRCT, MPO
65  2019 A Case Report of Multiple Myeloma Associated With Myeloperoxidase and Proteinase-3 Antibodies Posing a Diagnostic Dilemma. ANCA, MM, MPO
66  2019 A specific proteinase 3 activity footprint in α1-antitrypsin deficiency. alpha1-AT, COPD, NE
67  2019 ANCA positivity at the time of renal biopsy is associated with chronicity index of lupus nephritis. ANCA, LN
68  2019 ANCA-Associated Vasculitides and Hematologic Malignancies: Lessons from the Past and Future Perspectives. AAVs, GPA
69  2019 Anti-neutrophil Cytoplasmic Antibodies (ANCA) as Disease Activity Biomarkers in a "Personalized Medicine Approach" in ANCA-Associated Vasculitis. AAV, ANCA, MPO
70  2019 Association of Pulmonary Hemorrhage, Positive Proteinase 3, and Urinary Red Blood Cell Casts With Venous Thromboembolism in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. AAV, ANCA, HRs, VTE
71  2019 Can antineutrophil cytoplasmic antibody positivity at diagnosis predict the poor outcomes of Sjögren's syndrome? ESRD, ILD, MPO
72  2019 Clinical and histopathological prognostic factors affecting the renal outcomes in childhood ANCA-associated vasculitis. ANCA, ESRD, FFS, MPO
73  2019 Clinical characteristics of patients with vasculitis positive for anti-neutrophil cytoplasmic antibody targeting both proteinase 3 and myeloperoxidase: a retrospective study. ANCA, MPO
74  2019 Clinical significance of positive anti-neutrophil cytoplasmic antibodies without evidence of anti-neutrophil cytoplasmic antibodies-associated vasculitis. ANCA, cANCA, ELISA, MPO
75  2019 Co-occurrence of PLA2R-positive membranous nephropathy without crescents, and PR3-positive eosinophilic granulomatosis with polyangiitis
76  2019 Differences in clinico-pathological characteristics and outcomes between proteinase 3-ANCA positivity and myeloperoxidase-ANCA positivity in lupus nephritis. ANA, ANCA, LN, MPO
77  2019 Disease Activity, Antineutrophil Cytoplasmic Antibody Type, and Lipid Levels in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. ANCA, CVD, RAVE
78  2019 Efficacy and Safety of Belimumab and Azathioprine for Maintenance of Remission in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis: A Randomized Controlled Study. ANCA, BVAS, HR, MPO, PSE
79  2019 Evaluation of 12 different assays for detecting ANCA in Chinese patients with GPA and MPA: a multicenter study in China. AAV, ANCA, CLIA, ELISA, GPA, IIF, LIA, MPA, MPO
80  2019 Evaluation of PR3-ANCA Status After Rituximab for ANCA-Associated Vasculitis. AAV, ANCA
81  2019 Exploring Frequencies of Circulating Specific Th17 Cells against Myeloperoxidase and Proteinase 3 in ANCA Associated Vasculitis. AAV, ANCA, AUC, CRP, ELISPOT, MPO, PBMCs, T-regs, Th17
82  2019 Immunoglobulins G from patients with ANCA-associated vasculitis are atypically glycosylated in both the Fc and Fab regions and the relation to disease activity. AAV, ANCA, MPO
83  2019 Increased proteinase 3 and neutrophil elastase plasma concentrations are associated with non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes. AAT, NAFLD, NE, NSPs
84  2019 Iterative Optimization of the Cyclic Peptide SFTI-1 Yields Potent Inhibitors of Neutrophil Proteinase 3. SFTI-1
85  2019 Measuring Circulating Complement Activation Products in Myeloperoxidase- and Proteinase 3-Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. ANCA, MPO, sC5b-9
86  2019 Multiple myeloma cell-derived IL-32gamma increases the immunosuppressive function of macrophages by promoting indoleamine 2,3-dioxygenase (IDO) expression. IDO, MM
87  2019 Peptidomimetic inhibitors targeting the membrane-binding site of the neutrophil proteinase 3. CG, mbPR3, NE
88  2019 Pericardial Tamponade: An Uncommon Clinical Presentation in cANCA Related Vasculitis and Glomerulonephritis in Association with Very High Titres of ANA. ANCA
89  2019 Personalized Medicine in ANCA-Associated Vasculitis ANCA Specificity as the Guide? ANCA, EGPA, GPA, MPA, MPO
90  2019 Premedication with a cathepsin C inhibitor alleviates early primary graft dysfunction in mouse recipients after lung transplantation. CatC, ICatC, NE, NSPs
91  2019 Prevalence and Clinical Significance of Antineutrophil Cytoplasmic Antibodies in North American Patients With Idiopathic Pulmonary Fibrosis. ANCAs, IPF, MPO
92  2019 Proteinase 3 (PR3)-antineutrophil cytoplasmic antibody (ANCA)-associated vasculitic neuropathy in diffuse cutaneous systemic sclerosis: a rare duo. ANCAs, SSc
93  2019 Proteinase 3 phosphonic inhibitors. ---
94  2019 Remote Activation of a Latent Epitope in an Autoantigen Decoded With Simulated B-Factors. ANCAs, GPA
95  2019 Saint John on Patmos: Revelations of the Role of Antineutrophil Cytoplasmic Antibody (ANCA) in Vasculitis. ANCA, cANCA, MPO
96  2019 Should nasal biopsy inevitably be performed for classifying granulomatosis with polyangiitis in patients with rhinosinusitis? A retrospective chart review study. ANCA, GPA
97  2019 The association of serum interleukin-6 levels with clinical outcomes in antineutrophil cytoplasmic antibody-associated vasculitis. AAV, ANCA, AZA, CR, CYC, HR, MPO, RTX, sIL-6
98  2019 The complexity of classifying ANCA-associated small-vessel vasculitis in actual clinical practice: data from a multicenter retrospective survey. AAV, CHCC, MPO
99  2019 The effect of neutrophil serine proteases on human nasal epithelial cell barrier function. CBF, CG, ELISA, HNEC-ALI, IL-6, NE, PE, TER, ZO-1
100  2019 [Changes and clinical significance of serum proteinase 3 in latent autoimmune diabetes in adults]. BMI, ELISA, LADA, ROC, T2DM