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Abbreviation : PR3
Long Form : proteinase 3
No. Year Title Co-occurring Abbreviation
2021 Activity-Based Probes to Utilize the Proteolytic Activity of Cathepsin G in Biological Samples. ABPs, CatG, CyTOF, NSP4
2021 Advances in the genomics of ANCA-associated vasculitis-a view from East Asia. AAV, ANCA, GWAS, MPA, MPO
2021 ANCA Status or Clinical Phenotype - What Counts More? ANCA, GPA, MPA, MPO
2021 ANCA-Associated Vasculitis: An Update. ANCA, EGPA, GPA, MPA, MPO
2021 Antibody subtypes and titers predict clinical outcomes in ANCA-associated vasculitis. AAV, ANCA, ESRD, MPO
2021 Antineutrophil cytoplasmic antibodies (ANCA) - their role in pathogenesis, diagnosis, and treatment monitoring of ANCA-associated vasculitis. ANCA, MPO, NETs
2021 Autoantibodies Against Lysosome Associated Membrane Protein-2 (LAMP-2) in Pediatric Chronic Primary Systemic Vasculitis. ANCA, CRP, ESR, GFR, LAMP-2, MPO, pVAS
2021 Cathepsin C promotes breast cancer lung metastasis by modulating neutrophil infiltration and neutrophil extracellular trap formation. CTSC, IL-1beta, NETs
2021 Characterization of CD177-reactive iso- and auto-antibodies. MoAb
10  2021 Differences between myeloperoxidase-antineutrophil cytoplasmic autoantibody (ANCA) and proteinase 3-ANCA associated vasculitis: A retrospective study from a single center in China. ANCA, ANCA, MPO
11  2021 Isotretinoin induced small vessel vasculitis: a life-threatening pulmonary-renal syndrome-a case report. ANCA, DV
12  2021 Lack of elevated pre-ART elastase-ANCA levels in patients developing TB-IRIS. ANCAs, ART, MPO, TB-IRIS
13  2021 Long-term validation of the renal risk score for vasculitis in a Southern European population. ANCA, CI, ESRD, HR, MPO
14  2021 Neutrophil Elastase and Proteinase 3 Cleavage Sites Are Adjacent to the Polybasic Sequence within the Proteolytic Sensitive Activation Loop of the SARS-CoV-2 Spike Protein. CatG, NE, NSP4, S protein
15  2021 Prevalence and risk factors of relapse in patients with ANCA-associated vasculitis receiving cyclophosphamide induction: a systematic review and meta-analysis of large observational studies. AAV, aHRs, CIs, CRRs
16  2021 Proliferative glomerulonephritis and mantle cell lymphoma: a rare association. ANCA, MCL
17  2021 Protease-Specific Biomarkers to Analyse Protease Inhibitors for Emphysema Associated with Alpha 1-Antitrypsin Deficiency. An Overview of Current Approaches. AAT, AATD, COPD, NE
18  2021 The biology, pathogenetic role, clinical implications, and open issues of serum anti-neutrophil cytoplasmic antibodies. AAV, ANCA, MPO
19  2021 What is the meaning of ANCA positivity in IgG4-related disease? ANCA, ELISA, IgG4-RD, IIF, MPO, P-ANCA
20  2021 [Serpins as important protective factors in the pathogenesis of acute lung injury/acute respiratory distress syndrome]. ALI/ARDS, CG, NE, NSP4, NSPs, SIRS, SP-D
21  2020 4C3 Human Monoclonal Antibody: A Proof of Concept for Non-pathogenic Proteinase 3 Anti-neutrophil Cytoplasmic Antibodies in Granulomatosis With Polyangiitis. ANCA, GPA, mAb
22  2020 A Case of Diffuse Alveolar Hemorrhage Associated with High-Titer of MPO-ANCA Demonstrating Cytoplasmic Staining Pattern. AAV, DAH, IIF, MPO
23  2020 An unusual presentation of propylthiouracil-induced anti-MPO and PR3 positive ANCA vasculitis with associated anti-GBM antibodies, IgA nephropathy and an IgG4 interstitial infiltrate: a case report. AAV, ANCA, GBM, MPO, PTU
24  2020 Anti-neutrophil cytoplasmic antibodies (ANCA): Antigen interactions and downstream effects. ANCA, MPO
25  2020 Anti-neutrophil cytoplasmic antibodies predate symptom onset of ANCA-associated vasculitis. A case-control study. AAV, ANCA, MPO
26  2020 Antineutrophil Cytoplasmic Antibody in Lupus Nephritis: Correlation with Clinicopathological Characteristics and Disease Activity. ANCA, anti-GBM autoAb, LN, MPO, SLE, SLEDAI
27  2020 Association of Cigarette Smoking With Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. ANCA, CIs, MPO, OR
28  2020 Cerebrospinal fluid biomarkers implicated in the pathogenesis of anti-neutrophil cytoplasmic antibody-related hypertrophic pachymeningitis. ANCA, ANCA-HP, BAFF, CSF, HP, MPO, MS, NIND, TGF-beta1
29  2020 Characteristics and prognosis of ANCA-positive retroperitoneal fibrosis: A systematic literature review. ANCA, MPO, RPF
30  2020 Clinical characteristics, the diagnostic criteria and management recommendation of otitis media with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (OMAAV) proposed by Japan Otological Society. ANCA, EGPA, GPA, JOS, MPA, MPO, OMAAV
31  2020 Concerted actions by MMPs, ADAMTS and serine proteases during remodeling of the cartilage callus into bone during osseointegration of hip implants. NE, OA, SLPI, TIMP
32  2020 Current Understanding and Unknown Aspects of the Treatment of Granulomatosis with Polyangiitis (Wegener's Granulomatosis): Opportunities for Future Studies. ANCA, CYP, GPA, IVIG, RTX
33  2020 Dissociation between airway and systemic autoantibody responses in chronic obstructive pulmonary disease. COPD, CTD-ILD, MPO, Sm, TPO, U1 snRNP
34  2020 Distinct HLA and non-HLA associations in different subtypes of ANCA-associated vasculitides in North India. AAV, CTLA-4, GPA, HLA, PCR-SSP, PTPN22
35  2020 Galectin-1 Facilitates Macrophage Reprogramming and Resolution of Inflammation Through IFN-beta. Gal-1, IFN-beta, IL-10, IL-12
36  2020 Human proteinase 3 resistance to inhibition extends to alpha-2 macroglobulin. 39pep-alpha2-M, alpha1-PI, alpha2M, CatG, hNE, MNEI, NE
37  2020 Immunopathogenesis of ANCA-Associated Vasculitis. ANCA, EGPA, GPA, MPA, MPO
38  2020 Incidence and Risk Factors of Venous Thromboembolic Events in Patients with ANCA-Glomerulonephritis: A Cohort Study from the Maine-Anjou Registry. AAV, ANCA, VTE
39  2020 Membranous Nephropathy with Proteinase 3-ANCA-associated Vasculitis Successfully Treated with Rituximab. ANCA, ANCA-GN, MN
40  2020 Pathogenesis of ANCA-associated vasculitis: an emerging role for immunometabolism. AAV, ANCA, MPO
41  2020 Perspectives on signaling for biological- and processed food-related advanced glycation end-products and its role in cancer progression. AGEs, RAGE, Rb
42  2020 PR3 levels are impaired in plasma and PBMCs from Arabs with cardiovascular diseases. ANX3, CVD, MMP-9, PBMCs
43  2020 Proteinase 3 Autoreactivity in Anti-Neutrophil Cytoplasmic Antibody-associated vasculitis-Immunological versus clinical features. AAV, ANCA, MPO
44  2020 Proteinase-3-anti-neutrophil cytoplasmic antibodies (PR3-ANCAs) predict relapses in ANCA-associated vasculitis patients after rituximab. ANCA, MPO, PR3-ANCAs, RI, RTX
45  2020 Simultaneous presentation of granulomatosis with polyangiitis (GPA) and immunoglobulin G4-related disease (IgG4-RD). Leaving an open question: widening the spectrum of a single disease or real overlap? ANCA, GPA, IgG4-RD, IgG4-RD
46  2020 Subcutaneous Immunoglobulin for Antibody Deficiency in Antineutrophil Cytoplasmic Antibody (ANCA)-associated Vasculitis. ANCA, CYC, HG, IVIG, RTX, SCIG
47  2020 The performance of the chemiluminescent immunoassay for measuring serum myeloperoxidase and proteinase 3 antibodies. ANCA, AUC, CIA, ELISA, GPA, HC group, IC group, MPA, MPO, ROC
48  2020 The search for the Holy Grail: autoantigenic targets in primary sclerosing cholangitis associated with disease phenotype and neoplasia. ANCA, autoAbs, GP2, IBD, PSC
49  2020 WT1, PRAME, and PR3 mRNA Expression in Acute Myeloid Leukemia (AML). AML, PRAME, TAAs
50  2020 [ANCA diagnostics in vasculitis]. AAV, ANCA, MPO
51  2020 [Value of anti-neutrophil cytoplasmic antibody in assessing the severity of bronchiolitis obliterans in children]. ANCA, BO, HRCT, MPO
52  2019 A Case Report of Multiple Myeloma Associated With Myeloperoxidase and Proteinase-3 Antibodies Posing a Diagnostic Dilemma. ANCA, MM, MPO
53  2019 A specific proteinase 3 activity footprint in α1-antitrypsin deficiency. alpha1-AT, COPD, NE
54  2019 ANCA positivity at the time of renal biopsy is associated with chronicity index of lupus nephritis. ANCA, LN
55  2019 ANCA-Associated Vasculitides and Hematologic Malignancies: Lessons from the Past and Future Perspectives. AAVs, GPA
56  2019 Anti-neutrophil Cytoplasmic Antibodies (ANCA) as Disease Activity Biomarkers in a "Personalized Medicine Approach" in ANCA-Associated Vasculitis. AAV, ANCA, MPO
57  2019 Association of Pulmonary Hemorrhage, Positive Proteinase 3, and Urinary Red Blood Cell Casts With Venous Thromboembolism in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. AAV, ANCA, HRs, VTE
58  2019 Can antineutrophil cytoplasmic antibody positivity at diagnosis predict the poor outcomes of Sjögren's syndrome? ESRD, ILD, MPO
59  2019 Clinical and histopathological prognostic factors affecting the renal outcomes in childhood ANCA-associated vasculitis. ANCA, ESRD, FFS, MPO
60  2019 Clinical characteristics of patients with vasculitis positive for anti-neutrophil cytoplasmic antibody targeting both proteinase 3 and myeloperoxidase: a retrospective study. ANCA, MPO
61  2019 Clinical significance of positive anti-neutrophil cytoplasmic antibodies without evidence of anti-neutrophil cytoplasmic antibodies-associated vasculitis. ANCA, cANCA, ELISA, MPO
62  2019 Co-occurrence of PLA2R-positive membranous nephropathy without crescents, and PR3-positive eosinophilic granulomatosis with polyangiitis
. ANCA, EGPA, PLA2R, PMN
63  2019 Differences in clinico-pathological characteristics and outcomes between proteinase 3-ANCA positivity and myeloperoxidase-ANCA positivity in lupus nephritis. ANA, ANCA, LN, MPO
64  2019 Disease Activity, Antineutrophil Cytoplasmic Antibody Type, and Lipid Levels in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. ANCA, CVD, RAVE
65  2019 Efficacy and Safety of Belimumab and Azathioprine for Maintenance of Remission in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis: A Randomized Controlled Study. ANCA, BVAS, HR, MPO, PSE
66  2019 Evaluation of 12 different assays for detecting ANCA in Chinese patients with GPA and MPA: a multicenter study in China. AAV, ANCA, CLIA, ELISA, GPA, IIF, LIA, MPA, MPO
67  2019 Evaluation of PR3-ANCA Status After Rituximab for ANCA-Associated Vasculitis. AAV, ANCA
68  2019 Exploring Frequencies of Circulating Specific Th17 Cells against Myeloperoxidase and Proteinase 3 in ANCA Associated Vasculitis. AAV, ANCA, AUC, CRP, ELISPOT, MPO, PBMCs, T-regs, Th17
69  2019 Immunoglobulins G from patients with ANCA-associated vasculitis are atypically glycosylated in both the Fc and Fab regions and the relation to disease activity. AAV, ANCA, MPO
70  2019 Increased proteinase 3 and neutrophil elastase plasma concentrations are associated with non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes. AAT, NAFLD, NE, NSPs
71  2019 Iterative Optimization of the Cyclic Peptide SFTI-1 Yields Potent Inhibitors of Neutrophil Proteinase 3. SFTI-1
72  2019 Measuring Circulating Complement Activation Products in Myeloperoxidase- and Proteinase 3-Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. ANCA, MPO, sC5b-9
73  2019 Multiple myeloma cell-derived IL-32gamma increases the immunosuppressive function of macrophages by promoting indoleamine 2,3-dioxygenase (IDO) expression. IDO, MM
74  2019 Peptidomimetic inhibitors targeting the membrane-binding site of the neutrophil proteinase 3. CG, mbPR3, NE
75  2019 Pericardial Tamponade: An Uncommon Clinical Presentation in cANCA Related Vasculitis and Glomerulonephritis in Association with Very High Titres of ANA. ANCA
76  2019 Personalized Medicine in ANCA-Associated Vasculitis ANCA Specificity as the Guide? ANCA, EGPA, GPA, MPA, MPO
77  2019 Premedication with a cathepsin C inhibitor alleviates early primary graft dysfunction in mouse recipients after lung transplantation. CatC, ICatC, NE, NSPs
78  2019 Prevalence and Clinical Significance of Antineutrophil Cytoplasmic Antibodies in North American Patients With Idiopathic Pulmonary Fibrosis. ANCAs, IPF, MPO
79  2019 Proteinase 3 (PR3)-antineutrophil cytoplasmic antibody (ANCA)-associated vasculitic neuropathy in diffuse cutaneous systemic sclerosis: a rare duo. ANCAs, SSc
80  2019 Proteinase 3 phosphonic inhibitors. ---
81  2019 Remote Activation of a Latent Epitope in an Autoantigen Decoded With Simulated B-Factors. ANCAs, GPA
82  2019 Saint John on Patmos: Revelations of the Role of Antineutrophil Cytoplasmic Antibody (ANCA) in Vasculitis. ANCA, cANCA, MPO
83  2019 Should nasal biopsy inevitably be performed for classifying granulomatosis with polyangiitis in patients with rhinosinusitis? A retrospective chart review study. ANCA, GPA
84  2019 The association of serum interleukin-6 levels with clinical outcomes in antineutrophil cytoplasmic antibody-associated vasculitis. AAV, ANCA, AZA, CR, CYC, HR, MPO, RTX, sIL-6
85  2019 The complexity of classifying ANCA-associated small-vessel vasculitis in actual clinical practice: data from a multicenter retrospective survey. AAV, CHCC, MPO
86  2019 The effect of neutrophil serine proteases on human nasal epithelial cell barrier function. CBF, CG, ELISA, HNEC-ALI, IL-6, NE, PE, TER, ZO-1
87  2019 [Changes and clinical significance of serum proteinase 3 in latent autoimmune diabetes in adults]. BMI, ELISA, LADA, ROC, T2DM
88  2018 Adolescent PR3-ANCA-positive hypertrophic pachymeningitis: A case report and review of the literature. ANCA, HP
89  2018 Anti-neutrophil cytoplasm antibodies (ANCA): Recent methodological advances-Lead to new consensus recommendations for ANCA detection. ANCA, IIF, MPO
90  2018 Anti-plasminogen antibodies in ANCA-associated vasculitis: An optimized anti-plasminogen assay. AAV, ANCA, ELISA, glu-PLG, lys-PLG, MPO, PLG
91  2018 Antigen-Specific Detection of Autoantibodies Against Myeloperoxidase (MPO) and Proteinase 3 (PR3). MPO
92  2018 Borderline positive antineutrophil cytoplasmic antibodies (ANCA)-PR3/MPO detection in a large cohort tertiary center: lessons learnt from a real-life experience. ANCA, ELISA, IIF, MPO
93  2018 Case report: de novo ANCA-associated vasculitis after kidney transplantation treated with rituximab and plasma exchange. ANCA
94  2018 Design, Synthesis, and Enzymatic Evaluation of Novel ZnO Quantum Dot-Based Assay for Detection of Proteinase 3 Activity. QDs
95  2018 Excessive neutrophil extracellular trap formation in ANCA-associated vasculitis is independent of ANCA. AAV, ANCAs, MPO, NETs
96  2018 Exploiting the S4-S5 Specificity of Human Neutrophil Proteinase 3 to Improve the Potency of Peptidyl Di(chlorophenyl)-phosphonate Ester Inhibitors: A Kinetic and Molecular Modeling Analysis. ---
97  2018 Impact of Proteinase 3 versus Myeloperoxidase Positivity on Risk of End-Stage Renal Disease in ANCA-Associated Glomerulonephritis Stratified by Histological Classification: A Population-Based Cohort Study. ESRD, NKBR
98  2018 Increased formation of neutrophil extracellular traps is associated with gut leakage in patients with type 1 but not type 2 diabetes. ANCA, C5a, LPS, NE, NETs, PAD4, T2D
99  2018 Interaction between CD177 and platelet endothelial cell adhesion molecule-1 downregulates membrane-bound proteinase-3 (PR3) expression on neutrophils and attenuates neutrophil activation induced by PR3-ANCA. ANCA, DHR, ELISA, GEnC, Ig, MACS, mPR3, PECAM-1, sICAM-1, TNF-alpha
100  2018 Intractable Otitis Media Presenting as Falsely Positive for Proteinase 3-ANCA: A Case Report. MRSA