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[Related PubMed/MEDLINE]
Total Number of Papers: 845
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| Abbreviation |
: PhIP |
| Long Form |
: 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine |
|
| No. |
Year |
Title |
Co-occurring Abbreviation |
| 1 |
2022 |
A Prospective Pooled Analysis of Meat Mutagens and Colorectal Adenoma and Cancer in the US and EPIC Studies: Findings with an Emphasis on Improving Exposure Measurements. |
CRA, CRC, HCAs, MDM |
| 2 |
2022 |
Advancing metabolic networks and mapping updated urinary metabolic fingerprints after exposure to typical carcinogenic heterocyclic aromatic amines. |
HAAs |
| 3 |
2022 |
Assessment of heterocyclic aromatic amines contents in flamed and braised chicken in Burkina Faso. |
HAAs, IQ |
| 4 |
2022 |
Effect of acrolein, a lipid oxidation product, on the formation of the heterocyclic aromatic amine 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in model systems and roasted tilapia fish patties. |
--- |
| 5 |
2022 |
Heterocyclic amines detected in cooked meats and fishes from street markets and restaurants in the city of Hanoi, Vietnam: A Pilot local field investigation findings in 2020. |
HAAs |
| 6 |
2022 |
In vitro and in vivo low-dose exposure of simulated cooking oil fumes to assess adverse biological effects. |
COFs, HAAs, ROS, TDA |
| 7 |
2022 |
Inhibitory Effect of Tamarix ramosissima Extract on the Formation of Heterocyclic Amines in Roast Lamb Patties by Retarding the Consumption of Precursors and Preventing Free Radicals. |
ESR, HA, TRE |
| 8 |
2022 |
Olive leaf (Olea europaea L. folium) extract influences liver microsomal detoxifying enzymes in rats orally exposed to 2-amino-l-methyI-6-phenyI-imidazo pyridine (PhIP). |
GC/MS, PAHs |
| 9 |
2022 |
S-Allylcysteine Potently Protects against PhIP-Induced DNA Damage via Nrf2/AhR Signaling Pathway Modulation in Normal Human Colonic Mucosal Epithelial Cells. |
HO-1, Keap1, Nrf2, SAC |
| 10 |
2022 |
Simultaneous kinetics formation of heterocyclic amines and polycyclic aromatic hydrocarbons in phenylalanine model system. |
BbF, Ea, HCAs, PAHs |
| 11 |
2022 |
Synergistic Inhibitory Effects of Selected Amino Acids on the Formation of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in both Benzaldehyde- and Phenylacetaldehyde-Creatinine Model Systems. |
GC-MS |
| 12 |
2022 |
The Cooked Meat Carcinogen 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine Hair Dosimeter, DNA Adductomics Discovery, and Associations with Prostate Cancer Pathology Biomarkers. |
BPH, HAA, LPO, PC |
| 13 |
2022 |
The effect of PhIP precursors on the generation of particulate matter in cooking oil fumes at high cooking temperatures and the inflammation response in human lung cells. |
COFs, HCAs, PAHs |
| 14 |
2021 |
Application of HepG2/C3A liver spheroids as a model system for genotoxicity studies. |
2AA, 4NQO |
| 15 |
2021 |
Bioinformatic Analysis Identified Hub Genes Associated with Heterocyclic Amines Induced Cytotoxicity of Peripheral Blood Mononuclear Cells. |
HCAs, IQ, PBMC |
| 16 |
2021 |
Colon Cancer Risk of a Westernized Diet Is Reduced in Mice by Feeding Cruciferous or Apiaceous Vegetables at a Lower Dose of Carcinogen but Not a Higher Dose. |
APIs and CRUs, WD |
| 17 |
2021 |
Cyanidin-3-O-glucoside and its metabolite protocatechuic acid ameliorate 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) induced cytotoxicity in HepG2 cells by regulating apoptotic and Nrf2/p62 pathways. |
C3G, PCA |
| 18 |
2021 |
Different properties of mammary carcinogenesis induced by two chemical carcinogens, DMBA and PhIP, in heterozygous BALB/c Trp53 knockout mice. |
DMBA, HRAS, Trp53 |
| 19 |
2021 |
Effects of ten vegetable oils on heterocyclic amine profiles in roasted beef patties using UPLC-MS/MS combined with principal component analysis. |
CO, GSO, HAs, IQx, OO, PO, RGO, RSO, SBO, SFO, TSO, WO |
| 20 |
2021 |
Effects of the Deacetylation Degree of Chitosan on 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) Formation in Chemical Models and Beef Patties. |
DD |
| 21 |
2021 |
Establishment of Novel Genotoxicity Assay System Using Murine Normal Epithelial Tissue-Derived Organoids. |
AA, MFs |
| 22 |
2021 |
Formation and Prediction of PhIP, Harman, and Norharman in Chemical Model Systems Containing Epicatechin under Various Reaction Conditions. |
--- |
| 23 |
2021 |
HepG2 spheroids as a biosensor-like cell-based system for (geno)toxicity assessment. |
DSB |
| 24 |
2021 |
In vitro mutagenicity of selected environmental carcinogens and their metabolites in MutaMouse FE1 lung epithelial cells. |
4-ABP, MF |
| 25 |
2021 |
Induction of mismatch repair deficiency, compromised DNA damage signaling and compound hypermutagenesis by a dietary mutagen in a cell-based model for Lynch syndrome. |
CRC, DDS, LOH, mES, MMR |
| 26 |
2021 |
Interaction pattern of histidine, carnosine and histamine with methylglyoxal and other carbonyl compounds. |
RT |
| 27 |
2021 |
Shrimp as a substantial source of carcinogenic heterocyclic amines. |
AalphaC, DMIP, HAs |
| 28 |
2021 |
Simultaneous quantitation of acrylamide, 5-hydroxymethylfurfural, and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine using UPLC-MS/MS. |
AA, HMF |
| 29 |
2021 |
Sub-chronic exposure to PhIP induces oxidative damage and DNA damage, and disrupts the amino acid metabolism in the colons of Wistar rats. |
HCAs |
| 30 |
2021 |
The dietary carcinogen PhIP activates p53-dependent DNA damage response in the colon of CYP1A-humanized mice. |
CYP1A2, hCYP1A |
| 31 |
2021 |
The inhibitory effects of yellow mustard (Brassica juncea) and its characteristic pungent ingredient allyl isothiocyanate (AITC) on PhIP formation: Focused on the inhibitory pathways of AITC. |
AITC |
| 32 |
2020 |
2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine Induced Colon Injury by Disrupting the Intestinal Bacterial Composition and Lipid Metabolic Pathways in Rats. |
--- |
| 33 |
2020 |
A Case-Control Study of Meat Mutagens and Colorectal Cancers in Viet Nam. |
CRC |
| 34 |
2020 |
Biological significance of aminophenyl-beta-carboline derivatives formed from co-mutagenic action of beta-carbolines and aniline and o-toluidine and its effect on tumorigenesis in humans: A review. |
HCAs |
| 35 |
2020 |
Caffeic acid assists microwave heating to inhibit the formation of mutagenic and carcinogenic PhIP. |
CV, MW |
| 36 |
2020 |
Chinese chive and Mongolian leek suppress heterocyclic amine formation and enhance nutritional profile of roasted cod. |
HAs |
| 37 |
2020 |
Colitis-induced IL11 promotes colon carcinogenesis. |
DSS, pSTAT3 |
| 38 |
2020 |
Colon Transcriptomics Reveals Sex-Dependent Metabolic Signatures in Response to 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine Treatment in C57BL/6N Mice. |
DEGs, HAAs |
| 39 |
2020 |
Formation of a creatinine thermal degradation product and its role and participation in the radical pathway of forming the pyridine ring of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). |
DFT, IT-TOF-MS |
| 40 |
2020 |
Heterocyclic aromatic amines in doner kebab: Quantitation using an efficient microextraction technique coupled with reversed-phase high-performance liquid chromatography. |
--- |
| 41 |
2020 |
Inhibitory effect of selected hydrocolloids on 2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine (PhIP) formation in chemical models and beef patties. |
--- |
| 42 |
2020 |
Isolation and structure elucidation of constituents of Citrus limon, Isodon japonicus, and Lansium domesticum as the cancer prevention agents. |
--- |
| 43 |
2020 |
Isorhamnetin and Hispidulin from Tamarix ramosissima Inhibit 2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine (PhIP) Formation by Trapping Phenylacetaldehyde as a Key Mechanism. |
HAs, TRE, UPLC-MS |
| 44 |
2020 |
Metformin potentiates the chemotherapeutic effects of doxorubicin on 2-amino-1-methyl-6-phenylimidazo[4,5b] pyridine-induced Mammary Carcinoma in rats. |
DOX, MET, SD |
| 45 |
2020 |
Mutagenicity of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine (N-OH-PhIP) in human TP53 knock-in (Hupki) mouse embryo fibroblasts. |
N-OH-PhIP, WGS |
| 46 |
2020 |
Nano-sulforaphane attenuates PhIP-induced early abnormal embryonic neuro-development. |
HAA, NTDs, SFN |
| 47 |
2020 |
Preparation of a Broad-Spectrum Heterocyclic Aromatic Amines (HAAs) Antibody and Its Application in Detection of Eight HAAs in Heat Processed Meat. |
4,7,8-TriMeIQx, HAAs, icELISA, IQ |
| 48 |
2020 |
Target-specific micronucleus induction by colon carcinogens: 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 1,2-dimethylhydrazine. |
DMH |
| 49 |
2019 |
ABC transporters Mdr1a/1b, Bcrp1, Mrp2 and Mrp3 determine the sensitivity to PhIP/DSS-induced colon carcinogenesis and inflammation. |
ABC, DSS, WT |
| 50 |
2019 |
Anticancer effect of metformin against 2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine-induced rat mammary carcinogenesis is through AMPK pathway and modulation of oxidative stress markers. |
AMPK |
| 51 |
2019 |
Bioactivation of the tobacco carcinogens 4-aminobiphenyl (4-ABP) and 2-amino-9H-pyrido[2,3-b]indole (AalphaC) in human bladder RT4 cells. |
2-NA, 4-ABP, AAs, BC, CYP1, HAAs |
| 52 |
2019 |
Content, causes and analysis of heterocyclic amines in Chinese traditional braised chicken. |
ACs, AIAs, HCAs, PCA |
| 53 |
2019 |
Effect of Different Amino Acids and Heating Conditions on the Formation of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and Its Kinetics Formation Using Chemical Model System. |
Ea, HPLC-FLD |
| 54 |
2019 |
Effect of the metabolic capacity in rat liver S9 on the positive results of in vitro micronucleus tests. |
BaP, BNF, CPA, MI, PB |
| 55 |
2019 |
Evaluation of a 28-day repeated-dose micronucleus test in rat glandular stomach, colon, and liver using gastrointestinal tract-targeted genotoxic-carcinogens and non-carcinogens. |
GI, MN, MNU, NMUT |
| 56 |
2019 |
Haas in grilled meat: Determination using an advanced lab-on-a-chip flat electromembrane extraction coupled with on-line HPLC. |
IQ, LOC-FLEME |
| 57 |
2019 |
Indole: A Promising Scavenging Agent for Methylglyoxal and Related Carbonyls in Tryptophan Containing Maillard Model Systems. |
--- |
| 58 |
2019 |
Neuromelanin Modulates Heterocyclic Aromatic Amine-Induced Dopaminergic Neurotoxicity. |
HAAs, PD |
| 59 |
2019 |
Three-dimensional HepaRG spheroids as a liver model to study human genotoxicity in vitro with the single cell gel electrophoresis assay. |
2,4-DAT, 2-AAF, 4-NQO, CPA, DMBA, MMS |
| 60 |
2018 |
2,6-Dimethoxy-1,4-benzoquinone, isolation and identification of anti-carcinogenic, anti-mutagenic and anti-inflammatory component from the juice of Vitis coignetiae. |
DBQ |
| 61 |
2018 |
A comparison of mutagenic PhIP and beneficial 8-C-(E-phenylethenyl)quercetin and 6-C-(E-phenylethenyl)quercetin formation under microwave and conventional heating. |
6-CEPQ, 8-CEPQ |
| 62 |
2018 |
Alterations in the nigrostriatal dopamine system after acute systemic PhIP exposure. |
HCAs, PD |
| 63 |
2018 |
Apiaceous Vegetables and Cruciferous Phytochemicals Reduced PhIP-DNA Adducts in Prostate but Not in Pancreas of Wistar Rats. |
API, CRU |
| 64 |
2018 |
Biomonitoring an albumin adduct of the cooked meat carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in humans. |
ALB, LOD |
| 65 |
2018 |
Dose-dependent synergistic and antagonistic mutation responses of binary mixtures of the environmental carcinogen benzo[a]pyrene with food-derived carcinogens. |
AC, BaP, GA, MF, TK |
| 66 |
2018 |
Early detection of prostate carcinogens by immunohistochemistry of HMGB2. |
HMGB2 |
| 67 |
2018 |
Ethanol potentiates the genotoxicity of the food-derived mammary carcinogen PhIP in human estrogen receptor-positive mammary cells: mechanistic support for lifestyle factors (cooked red meat and ethanol) associated with mammary cancer. |
AhR, ERalpha, ROS |
| 68 |
2018 |
Genotoxicity of heterocyclic amines (HCAs) on freshly isolated human peripheral blood mononuclear cells (PBMC) and prevention by phenolic extracts derived from olive, olive oil and olive leaves. |
HCAs, IQ, PBMC |
| 69 |
2018 |
Inhibitory effect of mixture herbs/spices on formation of heterocyclic amines and mutagenic activity of grilled beef. |
HCAs, SPE |
| 70 |
2018 |
Inhibitory effects of catechins on beta-carbolines in tea leaves and chemical model systems. |
--- |
| 71 |
2018 |
Metabolic Activation of the Cooked Meat Carcinogen 2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine in Human Prostate. |
HAA, HONH-PhIP, NATs |
| 72 |
2018 |
Selective dopaminergic neurotoxicity of three heterocyclic amine subclasses in primary rat midbrain neurons. |
AIA, HCAs, PD |
| 73 |
2018 |
Structures and Antimutagenic Effects of Onoceranoid-Type Triterpenoids from the Leaves of Lansium domesticum. |
--- |
| 74 |
2018 |
The effects of different frying oils on the formation of heterocyclic aromatic amines in meatballs and the changes in fatty acid compositions of meatballs and frying oils. |
HCAs, MUFA, PUFA, SFAs |
| 75 |
2017 |
A miRNA signature for an environmental heterocyclic amine defined by a multi-organ carcinogenicity bioassay in the rat. |
HCAs, KLF4, miRNA |
| 76 |
2017 |
A Rapid Throughput Method To Extract DNA from Formalin-Fixed Paraffin-Embedded Tissues for Biomonitoring Carcinogenic DNA Adducts. |
4-ABP, AAI, FFPE |
| 77 |
2017 |
Divergent roles of p120-catenin isoforms linked to altered cell viability, proliferation, and invasiveness in carcinogen-induced rat skin tumors. |
--- |
| 78 |
2017 |
Formation of heterocyclic amines in Chinese marinated meat: effects of animal species and ingredients (rock candy, soy sauce and rice wine). |
HAAs |
| 79 |
2017 |
In vitro exposure of simulated meat-cooking fumes to assess adverse biological effects. |
--- |
| 80 |
2017 |
Lactoperoxidase, an Antimicrobial Milk Protein, as a Potential Activator of Carcinogenic Heterocyclic Amines in Breast Cancer. |
IQ, LPO |
| 81 |
2017 |
Metabolism of Foodborne Heterocyclic Aromatic Amines by Lactobacillus reuteri DSM 20016. |
HAA, IQ, PhIP-M1 |
| 82 |
2017 |
Structure-Activity Relationship (SAR) of Phenolics for 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) Formation in Phenylalanine/Creatinine Reaction Mixtures Including (or Not) Oxygen and Lipid Hydroperoxides. |
SAR |
| 83 |
2017 |
The effects of different spices and fat types on the formation of heterocyclic aromatic amines in barbecued sucuk. |
HCA |
| 84 |
2017 |
Unraveling the inhibitory effect of dihydromyricetin on heterocyclic aromatic amines formation. |
DMY, HAAs |
| 85 |
2016 |
2-amino-1-methyl-6-phenylimidazo(4,5-b) pyridine (PhIP) induces gene expression changes in JAK/STAT and MAPK pathways related to inflammation, diabetes and cancer. |
Egr-1, HCA, IBP5 |
| 86 |
2016 |
8-C-(E-phenylethenyl)quercetin from onion/beef soup induces autophagic cell death in colon cancer cells through ERK activation. |
8-CEPQ, ERK, MEK |
| 87 |
2016 |
A Prospective Analysis of Meat Mutagens and Colorectal Cancer in the Nurses' Health Study and Health Professionals Follow-up Study. |
CIs, CRC, HCAs, HPFS, HRs, MDM, MeIQx, NHS |
| 88 |
2016 |
Acid-labile protein-adducted heterocyclic aromatic amines in human blood are not viable biomarkers of dietary exposure: A systematic study. |
HCA |
| 89 |
2016 |
Aryl hydrocarbon receptor activation and CYP1A induction by cooked food-derived carcinogenic heterocyclic amines in human HepG2 cell lines. |
hAhR, HCAs |
| 90 |
2016 |
Bioactivation of Heterocyclic Aromatic Amines by UDP Glucuronosyltransferases. |
Gluc, HAA, HONH-PhIP, UGT |
| 91 |
2016 |
delta- and gamma-tocopherols inhibit phIP/DSS-induced colon carcinogenesis by protection against early cellular and DNA damages. |
DSS, hCYP1A |
| 92 |
2016 |
DNA adducts induced by food mutagen PhIP in a mouse model expressing human sulfotransferases 1A1 and 1A2. |
C8-PhIP-dG, SULTs, WT |
| 93 |
2016 |
Dose validation of PhIP hair level as a biomarker of heterocyclic aromatic amines exposure: a feeding study. |
--- |
| 94 |
2016 |
Effects of some cations on the formation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in a model system. |
--- |
| 95 |
2016 |
Effects of waxy rice starch and short chain amylose (SCA) on the formation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in a model system. |
SCA |
| 96 |
2016 |
From the Cover: PhIP/DSS-Induced Colon Carcinogenesis in CYP1A-Humanized Mice and the Possible Role of Lgr5+ Stem Cells. |
CRC, DSS |
| 97 |
2016 |
Human T lymphocytes bioactivate heterocyclic aromatic amines by forming DNA adducts. |
HAA |
| 98 |
2016 |
Impact of DNA repair on the dose-response of colorectal cancer formation induced by dietary carcinogens. |
BER, CRC, HCAs, MGMT, NER, NOC, O6-MeG, PoDs |
| 99 |
2016 |
Inhibition of 2-Amino-1-methyl-6-phenylimidazo [4,5-b]pyridine (PhIP) Formation by Alkoxy Radical Scavenging of Flavonoids and Their Quantitative Structure-Activity Relationship in a Model System. |
--- |
| 100 |
2016 |
Inhibitory Effect of Rosa rugosa Tea Extract on the Formation of Heterocyclic Amines in Meat Patties at Different Temperatures. |
HCAs, RTE |
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