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Abbreviation : RIPK2
Long Form : receptor-interacting serine/threonine-protein kinase 2
No. Year Title Co-occurring Abbreviation
2022 A pancancer analysis of the carcinogenic role of receptor-interacting serine/threonine protein kinase-2 (RIPK2) in human tumours. ---
2022 Discovery of Potent and Selective Receptor-Interacting Serine/Threonine Protein Kinase 2 (RIPK2) Inhibitors for the Treatment of Inflammatory Bowel Diseases (IBDs). IBDs, MDP
2022 High expression of RIPK2 is associated with Taxol resistance in serous ovarian cancer. cBioProtal, DEGs, GEO, OS, PFI, PPI, ssGSEA
2022 Identification and expression profiling of receptor-interacting serine/threonine-protein kinase 2 in Siberian sturgeon (Acipenser baerii). AbRIPK2, CARD, KD, PGN
2022 Identification of key genes for hypertrophic cardiomyopathy using integrated network analysis of differential lncRNA and gene expression. AKT1, AMPD2, ATG16L1, ATG5, CARD9, GEO, GNAI1, GNAI2, GNAI3, GNAS, GNB1, GNG12, GNG13, GNG2, GNGT1, GO, HCM, IFIH1, KEGG, lncRNAs, MAVS, MIR22HG, mRNAs, NOD1, NOD2, PPI, SERPINF1, SNHG12, TAF12, TBK1, UNKL, vWF, WDR81
2021 14-3-3 and erlin proteins differentially interact with RIPK2 complexes. ---
2021 Activation of RIPK2-mediated NOD1 signaling promotes proliferation and invasion of ovarian cancer cells via NF-κB pathway. NOD1
2021 ASKA technology-based pull-down method reveals a suppressive effect of ASK1 on the inflammatory NOD-RIPK2 pathway in brown adipocytes. ASK1, ASKA, UCP1
2021 Nodosome Inhibition as a Novel Broad-Spectrum Antiviral Strategy against Arboviruses, Enteroviruses, and SARS-CoV-2. COVID-19, NOD2, SARS-CoV-2, ZIKV
10  2021 Optimization of a Series of RIPK2 PROTACs. IAP
11  2021 Receptor-Interacting Serine/Threonine-Protein Kinase-2 as a Potential Prognostic Factor in Colorectal Cancer. CRC, IL-6, IL-8, NF-kB, TNF, VEGFA
12  2021 RIPK2 as a New Therapeutic Target in Inflammatory Bowel Diseases. IBDs, NOD1, RIP2, TLRs
13  2021 RIPK2 is an unfavorable prognosis marker and a potential therapeutic target in human kidney renal clear cell carcinoma. CARD, KIRC
14  2021 Transcriptome-Wide High-Throughput m6A Sequencing of Differential m6A Methylation Patterns in the Human Rheumatoid Arthritis Fibroblast-Like Synoviocytes Cell Line MH7A. AA, GO, JAK3, KEGG, m6A, m6A-seq, RA, TNFRSF10A, WTAP
15  2020 Extended pharmacodynamic responses observed upon PROTAC-mediated degradation of RIPK2. PD, PK, PROTACs
16  2020 Gene Expression Alterations Associated with Oleuropein-Induced Antiproliferative Effects and S-Phase Cell Cycle Arrest in Triple-Negative Breast Cancer Cells. BCL10, BFAR, BIRC5, BNIP2, BNIP3, BRAF, CARD, CASP1, CASP14, CASP4, CASP6, CYCS, FADD, GADD45A, IAP, OL, PYD, TNBC, TNFRSF10A, TNFRSF21
17  2020 Postbiotics for NOD2 require nonhematopoietic RIPK2 to improve blood glucose and metabolic inflammation in mice. GTT, HFD, NOD, WT
18  2020 RIPK2 Dictates Insulin Responses to Tyrosine Kinase Inhibitors in Obese Male Mice. GTT, NOD, TKIs, WT
19  2019 RIPK2 polymorphisms and susceptibility to tuberculosis in a Western Chinese Han population. GTEx, Mtb, SNPs, TB
20  2019 XIAP controls RIPK2 signaling by preventing its deposition in speck-like structures. XIAP
21  2018 Alginate oligosaccharide enhances intestinal integrity of weaned pigs through altering intestinal inflammatory responses and antioxidant status. AOS, IRAK1, MyD88, NOD1, p-NF-kappaB, TLR4, TRAF6
22  2018 Association between receptor interacting serine/threonine kinase 2 polymorphisms and gastric cancer susceptibility. CI
23  2018 Effects of dietary supplementation with Lactobacillus acidophilus on the performance, intestinal physical barrier function, and the expression of NOD-like receptors in weaned piglets. ADG, DAO, IL-1beta, NF-kappaB, NLRP3, NLRs
24  2018 MicroRNA-135a Modulates Hepatitis C Virus Genome Replication through Downregulation of Host Antiviral Factors. CXCL12, miRNAs, MYD88
25  2017 Human dendritic cells activated with MV130 induce Th1, Th17 and IL-10 responses via RIPK2 and MyD88 signalling pathways. DCs, MyD88, PBP, RRTIs
26  2017 Inductive expression of the NOD1 signalling pathway in chickens infected with Salmonella pullorum. iE-DAP, NF-kappaB, NOD1, qRT-PCR
27  2017 Tyrosine kinase inhibitors of Ripk2 attenuate bacterial cell wall-mediated lipolysis, inflammation and dysglycemia. Nod1, TKIs
28  2016 Bacterial Muramyl Dipeptide (MDP) Restricts Human Cytomegalovirus Replication via an IFN-beta-Dependent Pathway. HCMV, IRF3, MDP, TBK1
29  2016 Peptidoglycan-linked protein A promotes T cell-dependent antibody expansion during Staphylococcus aureus infection. SpA
30  2016 Receptor-Interacting Protein Kinase-2 Inhibition by CYLD Impairs Antibacterial Immune Responses in Macrophages. ERK, IFN-gamma, IL-6, LM, NF-kappaB, NO, ROS, STAT1
31  2016 Role of nucleotide-binding oligomerization domain 1 (NOD1) and its variants in human cytomegalovirus control in vitro and in vivo. HCMV, KD, NOD1, NOD2
32  2016 The Prostaglandin E2-EP3 Receptor Axis Regulates Anaplasma phagocytophilum-Mediated NLRC4 Inflammasome Activation. COX-2, IL, mPGES-1, PGE2
33  2015 Asparagine attenuates hepatic injury caused by lipopolysaccharide in weaned piglets associated with modulation of Toll-like receptor 4 and nucleotide-binding oligomerisation domain protein signalling and their negative regulators. Asn, HSP70, IRAK1, LPS, NOD, TLR4
34  2015 Expression and activity of NOD1 and NOD2/RIPK2 signalling in mononuclear cells from patients with rheumatoid arthritis. ELISA, IL, MDP, NF-kappaB, NOD, OA, PBMCs, qPCR, RA, SFTCs, TNF
35  2015 The immunomodulatory effects of barettin and involvement of the kinases CAMK1alpha and RIPK2. CAMK1alpha, IL-10, MCP-1, ox-LDL
36  2014 Nod/Ripk2 signaling in dendritic cells activates IL-17A-secreting innate lymphoid cells and drives colitis in T-bet-/-.Rag2-/- (TRUC) mice. DCs, Nod
37  2013 Activation of NOD2/RIPK2 pathway induces mitochondrial injury to oligodendrocyte precursor cells in vitro and CNS demyelination in vivo. 7-NI, CC, nNOS, NO, NOD2, OPCs, PGN
38  2013 Fish oil increases muscle protein mass and modulates Akt/FOXO, TLR4, and NOD signaling in weanling piglets after lipopolysaccharide challenge. COX-2, FOXO, LD, LPS, MAFbx, MyD88, PUFAs, TNF, TRAF6
39  2012 Hepatitis B virus e antigen physically associates with receptor-interacting serine/threonine protein kinase 2 and regulates IL-6 gene expression. HBV
40  2012 Knockdown of receptor-interacting serine/threonine protein kinase-2 (RIPK2) affects EMT-associated gene expression in human hepatoma cells. EMT, FGFBP1, HepG2-shRIPK2, JAG1, KRT19, NF-kappaB, PAI-1, RGS2, SIP1, SNAI2, VIM
41  2012 The anti-inflammatory actions of IL-4 in human monocytes are not mediated by IL-10, RP105 or the kinase activity of RIPK2. ---
42  2012 The RIPK2 gene: a positional candidate for tick burden supported by genetic associations in cattle and immunological response of knockout mouse. SGE, SNP
43  2006 Assignment of the bovine receptor-interacting serine-threonine kinase 2 gene (RIPK2) to BTA14 with somatic and radiation cell hybrids. ---
44  2005 Microarray analysis identifies an aberrant expression of apoptosis and DNA damage-regulatory genes in multiple sclerosis. Bcl-2, CN, MS, PBMC, SODD, TRAIL