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Abbreviation : SERPIN
Long Form : serine protease inhibitor
No. Year Title Co-occurring Abbreviation
2022 Anticoagulant SERPINs: Endogenous Regulators of Hemostasis and Thrombosis. ---
2022 In silico docking screen identifies airway host protease targets for human SERPINs. ---
2022 Unfolding the cascade of SERPINA3: Inflammation to cancer. SERPINA3
2021 Deep mutational scanning of the plasminogen activator inhibitor-1 functional landscape. PAI-1
2021 Targeted SERPIN (TaSER): A dual-action antithrombotic agent that targets platelets for SERPIN delivery. GPIbalpha, TaSER, vWF
2021 The Expression Profile of Protease Inhibitors in the Airway Epithelial Cells after Allergen (Der p 1) Stimulation. Der p
2020 Hypothesis: Alpha-1-antitrypsin is a promising treatment option for COVID-19. AAT, NETs, NF-kappaB
2020 Post-Translational Modifications of Circulating Alpha-1-Antitrypsin Protein. AAT
2020 Sunitinib decreases the expression of KRT6A and SERPINB1 in 3D human epidermal models. ERK, HFSR, KRT, MAPK
10  2019 A Virus-Derived Immune Modulating Serpin Accelerates Wound Closure with Improved Collagen Remodeling. uPAR
11  2019 Recognition of Plasminogen Activator Inhibitor Type 1 as the Primary Regulator of Fibrinolysis. PAI-1, PAs, TAFI, tPA, VECs
12  2018 Molecular biomarkers of Graves' ophthalmopathy. GD, GO
13  2017 Increased kallistatin levels in patients with obesity and prediabetes compared to normal glucose tolerance. ---
14  2016 A small deletion in SERPINC1 causes type I antithrombin deficiency by promoting endoplasmic reticulum stress. AT, ER, INEL
15  2016 Progressive myoclonus epilepsy associated with neuroserpin inclusion bodies (neuroserpinosis). FENIB, tPA
16  2015 A small molecule PAI-1 functional inhibitor attenuates neointimal hyperplasia and vascular smooth muscle cell survival by promoting PAI-1 cleavage. CL-PAI-1, FGF, LRP1, PAI-1, uPA and tPA, VSMC
17  2015 Protease nexin 1 induces apoptosis of prostate tumor cells through inhibition of X-chromosome-linked inhibitor of apoptosis protein. PN-1, SHH
18  2015 Species-Specific Serological Detection for Schistosomiasis by Serine Protease Inhibitor (SERPIN) in Multiplex Assay. MFI
19  2014 Functional and dysfunctional conformers of human neuroserpin characterized by optical spectroscopies and Molecular Dynamics. FENIB, NS
20  2014 Identification and characterisation of eight novel SERPINA1 Null mutations. AAT, AATD, DBS
21  2014 PAI-1-regulated extracellular proteolysis governs senescence and survival in Klotho mice. PAI-1, SMS
22  2014 Pseudomonas aeruginosa elastase disrupts the cortisol-binding activity of corticosteroid-binding globulin. CBG, RCL
23  2014 Serine protease inhibitor (SERPIN) B1 suppresses cell migration and invasion in glioma cells. FAK, MMP-2
24  2013 Corticosteroid-binding globulin: structure-function implications from species differences. CBG, RCL, S-to-R
25  2013 Influence of pathogenic bacteria species present in the postpartum bovine uterus on proteome profiles. dpp, ENO1, PGAM1, PGLYRP1, PMN, SDS
26  2013 Novel Combinatorial Therapeutic Targeting of PAI-1 (SERPINE1) Gene Expression in Alzheimer's Disease. APP, PAI-1
27  2012 Hypoxia negatively regulates antimetastatic PEDF in melanoma cells by a hypoxia inducible factor-independent, autophagy dependent mechanism. HIF, PEDF, UTRs
28  2012 PAI-1, progress in understanding the clinical problem and its aetiology. tPA, uPA
29  2011 Rock bream (Oplegnathus fasciatus) serpin, protease nexin-1: transcriptional analysis and characterization of its antiprotease and anticoagulant activities. AA, LPS, PN-1, Rb
30  2011 SERPINE2, an inhibitor of plasminogen activators, is highly expressed in the human endometrium during the secretory phase. PAs
31  2011 The discovery of alpha1-antitrypsin and its role in health and disease. AAT, COPD
32  2010 Spatiotemporal expression of the serine protease inhibitor, SERPINE2, in the mouse placenta and uterus during the estrous cycle, pregnancy, and lactation. LC, PA
33  2010 The neuroprotective role of PEDF: implication for the therapy of neurological disorders. PEDF
34  2009 Serine protease inhibitor (SERPIN) B1 promotes oral cancer cell motility and is over-expressed in invasive oral squamous cell carcinoma. OSCC
35  2008 Transgenic overexpression of a stable Plasminogen Activator Inhibitor-1 variant. PAI-1
36  2006 SERPINB1 upregulation is associated with in vivo complex formation with neutrophil elastase and cathepsin G in a baboon model of bronchopulmonary dysplasia. BPD, CatG, HMM, HPLC, NE
37  2004 PAI-1 expression is required for epithelial cell migration in two distinct phases of in vitro wound repair. MLC, PAI-1
38  2004 Plasminogen activator inhibitor type-1 gene expression and induced migration in TGF-beta1-stimulated smooth muscle cells is pp60(c-src)/MEK-dependent. c-src, EGFR, PAI-1, TGF-beta1
39  2003 [Screening and cloning of genes encoding Schistosoma japonicum antigens related to the serum antibodies in Mirotus fortis]. GAPDH
40  2002 Differential mechanisms of plasminogen activator inhibitor-1 gene activation by transforming growth factor-beta and tumor necrosis factor-alpha in endothelial cells. BAECs, PAI-1, TGF-beta, TNF-alpha
41  2000 Selective consumption of thyroxine-binding globulin during cardiac bypass surgery. CABG, TBG, TTR
42  2000 SERPIN regulation of factor XIa. The novel observation that protease nexin 1 in the presence of heparin is a more potent inhibitor of factor XIa than C1 inhibitor. FXIa, LRP, PN-1
43  2000 Topological localization of plasminogen activator inhibitor type 2. ELISA, PAI-2, uPA
44  1999 Mutational analysis in antithrombin deficiency. ---
45  1998 Analysis of a structural determinant in thrombin-protease nexin 1 complexes that mediates clearance by the low density lipoprotein receptor-related protein. LRP, PN-1, Th-PN1
46  1998 Receptor-mediated activation of murine peritoneal macrophages by antithrombin III acts as a costimulatory signal for nitric oxide synthesis. ATIII, IFN-gamma, NO
47  1997 Mutation analysis and loss of heterozygosity of PEDF in central nervous system primitive neuroectodermal tumors. CNS, LOH, PEDF, PNETs, SSCP
48  1997 The efficient catabolism of thrombin-protease nexin 1 complexes is a synergistic mechanism that requires both the LDL receptor-related protein and cell surface heparins. LRP, PN-1, TH, uPA
49  1996 Complex regulation of plasminogen activator inhibitor type-1 (PAI-1) gene expression by serum and substrate adhesion. NRK, PAI-1