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Abbreviation : ST
Long Form : small T antigen
No. Year Title Co-occurring Abbreviation
2021 Evaluating the Epithelial-Mesenchymal Program in Human Breast Epithelial Cells Cultured in Soft Agar Using a Novel Macromolecule Extraction Protocol. EMT, HMECs
2021 Reciprocal transactivation of Merkel cell polyomavirus and high-risk human papillomavirus promoter activities and increased expression of their oncoproteins. HR-HPV, LT, MCPyV
2020 Immortalized normal human lung epithelial cell models for studying lung cancer biology. hTERT, LT, SV40
2020 Merkel Cell Polyomavirus Small T Antigen Activates Noncanonical NF-κB Signaling to Promote Tumorigenesis. HPyV, MCC, MCPyV, ncNF-kappaB, SASP
2020 Merkel Cell Polyomavirus Small Tumor Antigen Activates Matrix Metallopeptidase-9 Gene Expression for Cell Migration and Invasion. EMT, LSD, MCC, MCV, MMP-9
2020 STRIPAK directs PP2A activity toward MAP4K4 to promote oncogenic transformation of human cells. STRIPAK
2019 A fail-safe system to prevent oncogenesis by senescence is targeted by SV40 small T antigen. BTG2, HP1BP3, LT, OIS, SASP, SV40
2019 Dual inhibition of MDM2 and MDM4 in virus-positive Merkel cell carcinoma enhances the p53 response. LT, MCCs, MCV, TP53
2019 Merkel cell polyomavirus Tumor antigens expressed in Merkel cell carcinoma function independently of the ubiquitin ligases Fbw7 and beta-TrCP. LSD, LT-t, MCC, MCPyV
10  2019 The Ubiquitin-Specific Protease Usp7, a Novel Merkel Cell Polyomavirus Large T-Antigen Interaction Partner, Modulates Viral DNA Replication. EBV, LT, MCC, MCPyV, Usp7
11  2018 CCL17/TARC and CCR4 expression in Merkel cell carcinoma. LT, MCC, MCPyV
12  2017 Merkel cell polyomavirus recruits MYCL to the EP400 complex to promote oncogenesis. ChIP-seq, LT, MCC, PP2A
13  2016 Transformation by Polyomavirus Middle T Antigen Involves a Unique Bimodal Interaction with the Hippo Effector YAP. MT, PI3K, PP2A, shRNA
14  2015 Expression of the small T antigen of Lymphotropic Papovavirus is sufficient to transform primary mouse embryo fibroblasts. ER, HuPyV9, LPV, LT, MCPyV, MEFs, SV40
15  2015 Merkel cell polyomavirus T antigens promote cell proliferation and inflammatory cytokine gene expression. LT, MCV, Rb
16  2014 Malawi polyomavirus is a prevalent human virus that interacts with known tumor suppressors. LT, MWPyV, PP2A, SV40
17  2014 Papillomavirus E7 oncoproteins share functions with polyomavirus small T antigens. HPV-16, PyV, SV40
18  2013 Merkel cell polyomavirus (MCPyV) strains in Japanese merkel cell carcinomas (MCC) are distinct from Caucasian type MCPyVs: genetic variability and phylogeny of MCPyV genomes obtained from Japanese MCPyV-infected MCCs. LT, MCC, MCPyV
19  2013 Merkel cell polyomavirus small T antigen targets the NEMO adaptor protein to disrupt inflammatory signaling. IKKalpha, MCC, MCPyV, NEMO, PP2A, PP4C
20  2013 Merkel cell polyomavirus-positive Merkel cell carcinoma cells do not require expression of the viral small T antigen. LT, MCC, MCV, shRNAs
21  2013 The T antigen locus of Merkel cell polyomavirus downregulates human Toll-like receptor 9 expression. BKPyV, dsDNA, JCPyV, KIPyV, LT, MCCs, MCPyV, RE, SV40, TLR9, WUPyV
22  2012 p27kip1 protein levels reflect a nexus of oncogenic signaling during cell transformation. LT, PP2A
23  2011 Upregulation of miR-27a contributes to the malignant transformation of human bronchial epithelial cells induced by SV40 small T antigen. HBERST, miRNA, PP2A, SV40
24  2008 Clonal selection in malignant transformation of human fibroblasts transduced with defined cellular oncogenes. ---
25  2007 Ligand binding to the androgen receptor induces conformational changes that regulate phosphatase interactions. AF-1, AR, PP2A, SV40
26  2007 Structural and biochemical insights into the regulation of protein phosphatase 2A by small t antigen of SV40. PP2A
27  2007 Structural basis of PP2A inhibition by small t antigen. PP2A
28  2005 PP2A-dependent transactivation of the cyclin A promoter by SV40 ST is mediated by a cell cycle-regulated E2F site. LT, PP2A, SV40
29  2005 Simian virus 40 small t antigen mediates conformation-dependent transfer of protein phosphatase 2A onto the androgen receptor. AR, PP2A
30  2005 Tumorigenic study on hepatocytes coexpressing SV40 with Ras. hTERT, LT, PP2A
31  2004 Identification of specific PP2A complexes involved in human cell transformation. HEK, PP2A
32  2004 Identification of TAZ as a binding partner of the polyomavirus T antigens. hr-t, LT
33  2004 PP2A fulfills its promises as tumor suppressor: which subunits are important? PP2A, SV40
34  2003 SV40 early region oncoproteins and human cell transformation. LT, pRB, SV40 ER
35  2002 Enumeration of the simian virus 40 early region elements necessary for human cell transformation. ER, LT, SV40
36  2001 Polyomavirus small t antigen prevents retinoic acid-induced retinoblastoma protein hypophosphorylation and redirects retinoic acid-induced G0 arrest and differentiation to apoptosis. RA
37  2001 Streptogramin- and tetracycline-responsive dual regulated expression of p27(Kip1) sense and antisense enables positive and negative growth control of Chinese hamster ovary cells. CHO
38  1998 Signaling from polyomavirus middle T and small T defines different roles for protein phosphatase 2A. MT, PI3K, PP2A
39  1991 The polyomavirus early region gene in transgenic mice causes vascular and bone tumors. LT, MT, Py