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Abbreviation : SW
Long Form : swainsonine
No. Year Title Co-occurring Abbreviation
2021 Swainsonine Triggers Paraptosis via ER Stress and MAPK Signaling Pathway in Rat Primary Renal Tubular Epithelial Cells. ER, RTECs, TEM
2021 The plant secondary compound swainsonine reshapes gut microbiota in plateau pikas (Ochotona curzoniae). PSCs, SCFAs
2020 Effects of Ensiling Oxytropis glabra with Whole-Plant Corn at Different Proportions on Fermentation Quality, Alkaloid Swainsonine Content, and Lactic Acid Bacteria Populations. LAB, OG
2020 Swainsonine promotes apoptosis by impairing lysosomal function and inhibiting autophagic degradation in rat primary renal tubular epithelial cells. BafA1, RAPA, RTECs
2020 Unveiling of Swainsonine Biosynthesis via a Multibranched Pathway in Fungi. NRPS-PKS
2019 Maternal exposure to swainsonine impaired the early postnatal development of mouse dentate gyrus of offspring. DG, PND
2019 Sesquiterpenoids and mycotoxin swainsonine from the locoweed endophytic fungus Alternaria oxytropis. ---
2019 Swainsonine inhibits proliferation and collagen synthesis of NIH-3T3 cells by declining miR-21. alpha-SMA, miR-21, TGF-beta1
2019 Swainsonine protects H9c2 cells against lipopolysaccharide-induced apoptosis and inflammatory injury via down-regulating miR-429. LPS, PM
10  2019 Swainsonine, an alpha-mannosidase inhibitor, may worsen cervical cancer progression through the increase in myeloid derived suppressor cells population. HPV
11  2019 Transcriptome Profiles of Alternaria oxytropis Provides Insights into Swainsonine Biosynthesis. ---
12  2017 Alteration of the PI3K/Akt signaling pathway by swainsonine affects 17beta-Estradiol secretion in ovary cells. CHO
13  2017 The Biosynthesis Pathway of Swainsonine, a New Anticancer Drug from Three Endophytic Fungi. ---
14  2015 Aberrant glycosylation of alphavbeta3 integrin is associated with melanoma progression. GlcNAc, MAA, PHA-L, SNA, VN
15  2015 Alteration of glycan structures by swainsonine affects steroidogenesis in bovine luteal cells. LSCs
16  2015 Fyn arrests swainsonine-induced apoptosis in 293T cells via Akt and its phosphorylation. ---
17  2015 N-glycans and metastasis in galectin-3 transgenic mice. polyLacNAc
18  2015 Swainsonine-induced apoptosis pathway in cerebral cortical neurons. ---
19  2015 The effects of swainsonine on the activity and expression of alpha-mannosidase in BRL-3A cells. AMAN
20  2014 Exposure to swainsonine impairs adult neurogenesis and spatial learning and memory. AMA, GFAP, NPCs, SYP
21  2014 Molecular characterization of Capra hircus lysosomal alpha-mannosidase and potential mutant site for the therapy of locoweed poisoning. chLAM, LAM
22  2014 Purification and characterization of a class II alpha-Mannosidase from Moringa oleifera seed kernels. dMNJ
23  2014 Swainsonine induces apoptosis through mitochondrial pathway and caspase activation in goat trophoblasts. GTCs
24  2014 Swainsonine induces caprine luteal cells apoptosis via mitochondrial-mediated caspase-dependent pathway. ---
25  2013 Potential degradation of swainsonine by intracellular enzymes of Arthrobacter sp. HW08. ---
26  2013 Swainsonine differentially affects steroidogenesis and viability in caprine luteal cells invitro. ---
27  2012 Swainsonine as a lysosomal toxin affects dopaminergic neurons. AMA
28  2011 N-glycan-defective breast cancer cells induce a phenotypic switch in polarization of bone marrow-derived macrophages. BMDMs, MTT
29  2011 The immunomodulatory effects of Ipomoea carnea in rats vary depending on life stage. RA
30  2010 Effect of alpha3beta1 and alphavbeta3 integrin glycosylation on interaction of melanoma cells with vitronectin. VN
31  2008 Biodegradation of Swainsonine by Acinetobacter calcoaceticus strain YLZZ-1 and its isolation and identification. ---
32  2008 Effects of swainsonine on the humoral immune response of lipopolysaccharide. HA, LPS, MER-HA, PFC
33  2008 Poly N-acetyllactosamine substitutions on N- and not O-oligosaccharides or Thomsen-Friedenreich antigen facilitate lung specific metastasis of melanoma cells via galectin-3. BG, polylacNAc
34  2007 VIPL has sugar-binding activity specific for high-mannose-type N-glycans, and glucosylation of the alpha1,2 mannotriosyl branch blocks its binding. DMJ, ER, KIF, PE, SA, sVIPL, VIPL
35  2006 Cloning and expression of mouse cytosolic alpha-mannosidase (Man2c1). DIM
36  2006 Effects of N-glycan processing inhibitors on signaling events and induction of apoptosis in galectin-1-stimulated Jurkat T lymphocytes. 1-dMM, CD, Gal-1, Luc, PMA
37  2006 Evidence that maturation of the N-linked glycans of the respiratory syncytial virus (RSV) glycoproteins is required for virus-mediated cell fusion: The effect of alpha-mannosidase inhibitors on RSV infectivity. DMJ, RSV
38  2006 Immunological evaluation of SW-HSA conjugate on goats. HSA
39  2006 Toxicokinetic profile of swainsonine following exposure to locoweed (Oxytropis sericea) in naive and previously exposed sheep. ALKP, AST, BW
40  2005 Clearance of para-aminohippuric acid in wethers consuming locoweed. ALKP, AST, BW, PAH
41  2005 Does glycosylation of melanoma cells influence their interactions with fibronectin? FN
42  2005 Regulatory roles of altered N- and O-glycosylation of CD45 in galectin-1-induced cell death in human diffuse large B cell lymphoma. BZGalNAc, DLBCL
43  2005 The regulatory roles of cell surface sialylation and N-glycans in human B cell lymphoma cell adhesion to galectin-1. DLBCL
44  2004 Altered N-glycosylation in CD45 and regulatory roles of altered N-glycosylation in galectin-1-induced growth inhibition in human diffuse large B cell lymphoma. DLBCL
45  2004 Regulatory roles of N-glycosylation of immunoglobulin M in CD40-CD40L-mediated cell survival of human diffuse large B cell lymphoma. DLBCL, ELISA
46  2004 Relations of the type and branch of surface N-glycans to cell adhesion, migration and integrin expressions. ATRA, DMJ, FN, HUVEC
47  2003 The impact of N- and O-glycosylation on the functions of Glut-1 transporter in human thyroid anaplastic cells. DMJ, TM
48  2001 Molecular cloning and expression of an alpha-mannosidase gene in Mycobacterium tuberculosis. 4MU-Man, dMNJ, Mtb
49  2000 Effect of subacute swainsonine (locoweed; Oxytropis sericea) consumption on immunocompetence and serum constituents of sheep in a nutrient-restricted state. ---
50  2000 [Inhibition effect of Swainsonine on the growth and metastasis of gastric cancer in vivo]. ---
51  1999 The selective enzymatic synthesis of lipophilic esters of swainsonine. PPL
52  1998 Interaction of swainsonine with lymphoid and highly perfused tissues: a pharmacokinetics explanation for sustained immunomodulation. ---
53  1994 Role of processing of the oligosaccharide chains in the affinity of lipoprotein lipase for heparin. CSTP, dMM, ER, LPL, TUN
54  1994 Swainsonine augments the cytotoxicity of human lymphokine-activated killer cells against autologous thyroid cancer cells. LAK
55  1994 Swainsonine, a glycosylation inhibitor, enhances both lymphocyte efficacy and tumour susceptibility in LAK and NK cytotoxicity. IL-2, LAK, NK
56  1993 A preliminary pharmacokinetic evaluation of the antimetastatic immunomodulator swainsonine: clinical and toxic implications. ---
57  1993 Carbonoyloxy analogs of the anti-metastatic drug swainsonine. Activation in tumor cells by esterases. ---
58  1993 The N-linked oligosaccharides of the Fc epsilon receptors of rat basophilic leukemia cells. CN, DMJ
59  1992 Rapid and reversible inhibition of tyrosinase activity by glucosidase inhibitors in human melanoma cells. CS, dMM, dNM, TM
60  1992 The presence of concanavalin-A(Con-A)-like molecules on natural-killer (NK)-sensitive target cells: their possible role in swainsonine-augmented human NK cytotoxicity. Ab, alpha-MM, Con A, LGL, NK, PBL
61  1991 Carbohydrate synthesis inhibitors decrease interleukin 1-stimulated lymphocyte binding to endothelial cells. CAST, DMN, DN
62  1991 Dependence of mouse thymocyte-erythrocyte rosette formation on complete identity at class-I-MHC. ---
63  1991 Swainsonine, an inhibitor of mannosidase II during glycoprotein processing, enhances concanavalin A-induced T cell proliferation and interleukin 2 receptor expression exclusively via the T cell receptor complex. CAST, MNL, TCR
64  1990 Analysis of carbohydrate properties essential for melanogenesis in tyrosinases of cultured malignant melanoma cells by differential carbohydrate processing inhibition. CS, dNM, Glc, MS, TP
65  1990 Effect of glycosylation inhibitors on N-glycosylpeptides and on invasion of malignant mouse MO4 cells in vitro. CS, dNM, MON
66  1990 Swainsonine, an inhibitor of glycoprotein processing, enhances cytotoxicity of large granular lymphocytes. 1-DMN, 1-DN, LGL
67  1989 Effect of swainsonine on stimulation and cell cycle progression of human lymphocytes. ---
68  1989 Potentiation of human lymphokine-activated killer cell activity by swainsonine, an inhibitor of glycoprotein processing. IL-2, LAK
69  1988 Simultaneous inhibition of multiple steps in the processing of N-linked oligosaccharides does not impair immunoglobulin secretion from rat hybridoma cells. CSP, dMM, dNM
70  1987 Lysosomal delivery of the major myelin glycoprotein in the absence of myelin assembly: posttranslational regulation of the level of expression by Schwann cells. ---
71  1986 Inhibition of N-linked oligosaccharide processing does not prevent the secretion of thyroglobulin. A study with swainsonine and deoxynojirimycin. dNM
72  1986 Inhibition of N-linked oligosaccharide trimming mannosidases blocks human B cell development. dMM, Ig, PWM, SAC
73  1986 Oligosaccharide modification by swainsonine treatment inhibits pulmonary colonization by B16-F10 murine melanoma cells. ---
74  1985 The mannosidase inhibitors 1-deoxymannojirimycin and swainsonine have no effect on the biosynthesis and infectivity of Rous sarcoma virus. DIM, RSV
75  1985 Transformation by the v-fms oncogene product: role of glycosylational processing and cell surface expression. CA, MdN, SM-FRE
76  1983 Effects of the glucosidase inhibitors nojirimycin and deoxynojirimycin on the biosynthesis of membrane and secretory glycoproteins. dNM, NM