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Abbreviation : TB4
Long Form : thymosin beta4
No. Year Title Co-occurring Abbreviation
2022 Platelets and osteoblasts: secretome connections. ECM, SPARC, TIMP1
2022 Systemic gene therapy with thymosin β4 alleviates glomerular injury in mice. ADR
2022 Thymosin beta-4 improves endothelial function and reparative potency of diabetic endothelial cells differentiated from patient induced pluripotent stem cells. ICAM-1, T2DM
2021 Di-(2-ethylhexyl) phthalate-induced tumor growth is regulated by primary cilium formation via the axis of H2O2 production-thymosin beta-4 gene expression. CilioA, DEHP, FBS, PC, ROS
2021 Intra-Articular Injection of BPC 157 for Multiple Types of Knee Pain. MRIs, OA
2021 Thymosin beta-4 prenatal administration improves fetal development and halts side effects due to preterm delivery. ---
2021 Thymosin beta4 increases cardiac cell proliferation, cell engraftment, and the reparative potency of human induced-pluripotent stem cell-derived cardiomyocytes in a porcine model of acute myocardial infarction. hiPSC-CMs, MI, MRI
2018 No effect of thymosin beta-4 on the expression of the transcription factor Islet-1 in the adult murine heart. ---
2018 Sources of variability in quantifying circulating thymosin beta-4: literature review and recommendations. ---
10  2017 Effects of exogenous thymosin beta4 on carbon tetrachloride-induced liver injury and fibrosis. ---
11  2017 Thymosin Beta-4 Is Elevated in Women With Heart Failure With Preserved Ejection Fraction. HF
12  2017 Thymosin beta-4 regulates activation of hepatic stellate cells via hedgehog signaling. GLI2, Hh, HSC, ILK, pGSK-3B
13  2016 Plasma levels of F-actin and F:G-actin ratio as potential new biomarkers in patients with septic shock. SIRS
14  2016 Systemic Dosing of Thymosin Beta 4 before and after Ischemia Does Not Attenuate Global Myocardial Ischemia-Reperfusion Injury in Pigs. CPB, IRI
15  2015 C-terminal variable AGES domain of Thymosin beta4: the molecule's primary contribution in support of post-ischemic cardiac function and repair. ---
16  2015 Peptide fragment of thymosin beta4 increases hippocampal neurogenesis and facilitates spatial memory. GSK-3beta, VEGF
17  2015 Thymosin beta 4 is associated with RUNX2 expression through the Smad and Akt signaling pathways in mouse dental epithelial cells. AMBN, ENAM, p-Akt
18  2014 Thymosin beta4 regulates cardiac valve formation via endothelial-mesenchymal transformation in zebrafish embryos. AVC, BMP, EMT, HAS, TGF-beta, zTB4
19  2013 Effects of thymosin beta4 on the bone formation of calvarial defects in rats. RT-PCR
20  2012 Promoting effects of thymosin beta4 on granulation tissue and new bone formation after tooth extraction in rats. ---
21  2012 Stimulation of adult resident cardiac progenitor cells by durable myocardial expression of thymosin beta 4 with ultrasound-targeted microbubble delivery. UTMD
22  2011 Elevated expression of thymosin beta4, vascular endothelial growth factor (VEGF), and hypoxia inducible factor (HIF)-1alpha in early-stage cervical cancers. HIF, VEGF
23  2011 Markers of progenitor cell recruitment and differentiation rise early during ischemia and continue during resuscitation in a porcine acute ischemia model. AMI, CPR, VEGF
24  2011 Thymosin beta 4 treatment after myocardial infarction does not reprogram epicardial cells into cardiomyocytes. MI
25  2010 Actin-sequestering protein, thymosin beta-4, induces paclitaxel resistance through ROS/HIF-1alpha stabilization in HeLa human cervical tumor cells. HIF, NAC, ROS, TB4P
26  2010 Actin-sequestering protein, thymosin beta-4, is a novel hypoxia responsive regulator. sh, Tg, VEGF
27  2010 Exogenous thymosin beta4 prevents apoptosis in human intervertebral annulus cells in vitro. ---
28  2010 Quantification of thymosin beta(4) in human cerebrospinal fluid using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. CJD, CSF, MALDI-TOF MS
29  2009 Thymosin beta4 mediated PKC activation is essential to initiate the embryonic coronary developmental program and epicardial progenitor cell activation in adult mice in vivo. Bves, PKC
30  2008 Actin-sequestering protein, thymosin-beta-4 (TB4), inhibits caspase-3 activation in paclitaxel-induced tumor cell death. siRNA
31  2008 Hypoxia-inducible transcription factor (HIF)-1 alpha stabilization by actin-sequestering protein, thymosin beta-4 (TB4) in Hela cervical tumor cells. HIF, HRE, TB4P, VEGF
32  2008 Overexpression of thymosin beta-10 inhibits VEGF mRNA expression, autocrine VEGF protein production, and tube formation in hypoxia-induced monkey choroid-retinal endothelial cells. ---
33  2008 Quantitative mass spectrometry identifies drug targets in cancer stem cell-containing side population. ---
34  2007 Expressed transcripts associated with high rates of egg production in chicken ovarian follicles. ACADL, cycB2, FTH1, ING4, TXN
35  2007 Recombinant thymosin beta 4 can promote full-thickness cutaneous wound healing. DTT
36  2006 ERK activation by thymosin-beta-4 (TB4) overexpression induces paclitaxel-resistance. siRNA, TB4-HeLa
37  2004 Up-regulation of thymosin beta 4 gene expression in experimentally-induced uterine adenomyosis in mice. ---