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Abbreviation : TG
Long Form : transgenic mice
No. Year Title Co-occurring Abbreviation
2021 Overexpression of Isl1 under the Pax2 Promoter, Leads to Impaired Sound Processing and Increased Inhibition in the Inferior Colliculus. IC
2021 Serine Mutations in Hsp27 abrogate its ability to inhibit p53 dependent apoptosis and Doxorubicin-induced Heart Failure in mice. hHsp27, LVID, non-Tg, sHSPs
2021 Systemic Overexpression of GDF5 in Adipocytes but Not Hepatocytes Alleviates High-Fat Diet-Induced Nonalcoholic Fatty Liver in Mice. AST, GDF5, NAFLD
2020 Erythropoietin signaling in osteoblasts is required for normal bone formation and for bone loss during erythropoietin-stimulated erythropoiesis. BV, EPO, EpoR
2020 Human CYP2D6 in the Brain Is Protective Against Harmine-Induced Neurotoxicity: Evidence from Humanized CYP2D6 Transgenic Mice. i.c.v, WT
2020 Inward Rectifier K+ Currents Contribute to the Proarrhythmic Electrical Phenotype of Atria Overexpressing Cyclic Adenosine Monophosphate Response Element Modulator Isoform CREM-IbΔC-X. AF, CREM, KChIP2
2020 Upregulation of polycistronic microRNA-143 and microRNA-145 in colonocytes suppresses colitis and inflammation-associated colon cancer. CCC
2019 Deletion of Ripk3 Prevents Motor Neuron Death In Vitro but not In Vivo. MNs, PCD, RIPK1
2019 Heterogeneous Nuclear Ribonucleoprotein F Mediates Insulin Inhibition of Bcl2-Modifying Factor Expression and Tubulopathy in Diabetic Kidney. Bmf, hnRNP F, IRPTCs, MAPK, RPTC, siRNA
10  2019 Influenza Virus-Induced Robust Expression of SOCS3 Contributes to Excessive Production of IL-6. IAV, IL-6, NF-kappaB, SOCS3, STAT3
11  2019 Myofibroblast beta2 adrenergic signaling amplifies cardiac hypertrophy in mice. beta-AR, ISO
12  2019 Overexpression of the Lolium perenne L. delta1-pyrroline 5-carboxylate synthase (LpP5CS) gene results in morphological alterations and salinity tolerance in switchgrass (Panicum virgatum L.). P5CS
13  2019 Voluntary physical activity counteracts Chronic Heart Failure progression affecting both cardiac function and skeletal muscle in the transgenic Tgαq*44 mouse model. CHF, VFWR
14  2018 CaMKII-mediated phosphorylation of RyR2 plays a crucial role in aberrant Ca2+ release as an arrhythmogenic substrate in cardiac troponin T-related familial hypertrophic cardiomyopathy. FHC, ISO, SpF, SR, TnT
15  2018 Characterization of transgenic mice expressing EGFP under the control of the monkey 20alpha-hydroxysteroid dehydrogenase promoter. 20alpha-HSD, EGFP
16  2018 Data on the localization of EGFP and 20alpha-hydroxysteroid dehydrogenase (20alpha-HSD) in the placenta and testes of transgenic mice. 20alpha-HSD, EGFP
17  2017 B lymphocytes repress hepatic tumorigenesis but not development in Hras12V transgenic mice. BTK, IGF-1
18  2017 Characterization of the Genetic Program Linked to the Development of Atrial Fibrillation in CREM-IbDeltaC-X Mice. AF
19  2017 Dried plum alleviates symptoms of inflammatory arthritis in TNF transgenic mice. DP, IL, NC, NF-kappaB, NFATc1, RA, TNF, TRAP
20  2017 miR-146a mediates inflammatory changes and fibrosis in the heart in diabetes. HCMECs
21  2017 miR-146a regulates glucose induced upregulation of inflammatory cytokines extracellular matrix proteins in the retina and kidney in diabetes. ECM, ECM, ECs, STZ, WT
22  2017 Mode of Tolerance Induction and Requirement for Aire Are Governed by the Cell Types That Express Self-Antigen and Those That Present Antigen. BM, mTECs, TRAs
23  2017 Muscle-derived extracellular superoxide dismutase inhibits endothelial activation and protects against multiple organ dysfunction syndrome in mice. EC-SOD, LPS, MODS, WT
24  2017 Sex Impact on Tau-Aggregation and Postsynaptic Protein Levels in the P301L Mouse Model of Tauopathy. ctr, p-tau
25  2017 The transcriptional regulation of the human angiotensinogen gene after high-fat diet is haplotype-dependent: Novel insights into the gene-regulatory networks and implications for human hypertension. ChIP, hAGT, Hap, RAAS, SNPs
26  2017 Transgenic mice display hair loss and regrowth overexpressing mutant Hr gene. HF, Hr
27  2016 HSPA12B Attenuated Acute Myocardial Ischemia/reperfusion Injury via Maintaining Endothelial Integrity in a PI3K/Akt/mTOR-dependent Mechanism. I/R, WT
28  2016 Macrophage CGI-58 Attenuates Inflammatory Responsiveness via Promotion of PPARgamma Signaling. ATGL, CGI-58, HDAC, HFD, LPS, PPAR, WT
29  2016 Murine matrix metalloproteinase-20 overexpression stimulates cell invasion into the enamel layer via enhanced Wnt signaling. MMP20
30  2016 Overexpression of Na+/Ca2+ exchanger 1 display enhanced relaxation in the gastric fundus. EFS, WT
31  2016 Protective role of ACE2-Ang-(1-7)-Mas in myocardial fibrosis by downregulating KCa3.1 channel via ERK1/2 pathway. ACE2, Ang, DIZE, WT
32  2015 99mTc(CO)3-Labeled Benzothiazole Derivatives Preferentially Bind Cerebrovascular Amyloid: Potential Use as Imaging Agents for Cerebral Amyloid Angiopathy. AD, CAA
33  2015 Apolipoprotein D Transgenic Mice Develop Hepatic Steatosis through Activation of PPARgamma and Fatty Acid Uptake. AA, H-apoD, WT
34  2015 HSPA12B attenuates acute lung injury during endotoxemia in mice. ALI, COX-2, ERKs, HSPA12B, ICAM-1, LPS, VEGF, WT
35  2015 Over-expression of calpastatin inhibits calpain activation and attenuates post-infarction myocardial remodeling. CAST, MI, WT
36  2015 Rapamycin improves motor function, reduces 4-hydroxynonenal adducted protein in brain, and attenuates synaptic injury in a mouse model of synucleinopathy. ---
37  2014 Cathepsin K overexpression modifies lung development in newborn mice. CatK, PN, WT
38  2014 Enhanced defense against mitochondrial hydrogen peroxide attenuates age-associated cognition decline. dTg, PRDX3
39  2014 Na/Ca(2+) exchanger 1 transgenic mice display increased relaxation in the distal colon. EFS, NCX1, PKG, sGC, WT
40  2014 Overexpression of rod photoreceptor glutamic acid rich protein 2 (GARP2) increases gain and slows recovery in mouse retina. ERG, GARP2, PDE6, ROS
41  2014 Reduced striatal dopamine DA D2 receptor function in dominant-negative GSK-3 transgenic mice. DA, GSK-3, WT
42  2014 Sirtuin 6 protects the heart from hypoxic damage. Bcl-2, CK, LDH, NF-kappaB, p-AKT, PI, ROS, SIRT6, WT
43  2014 TDP-43 modification in the hSOD1(G93A) amyotrophic lateral sclerosis mouse model. ALS, FALS, FTLD, NDs, SP, TDP-43
44  2013 Active Component of Danshen (Salvia miltiorrhiza Bunge), Tanshinone I, Attenuates Lung Tumorigenesis via Inhibitions of VEGF, Cyclin A, and Cyclin B Expressions. CM, hVEGF-A 165
45  2013 Broad suppression of NADPH oxidase activity exacerbates ischemia/reperfusion injury through inadvertent downregulation of hypoxia-inducible factor-1α and upregulation of peroxisome proliferator-activated receptor-α. I/R, KO, NOX
46  2013 CCN family member 2/connective tissue growth factor (CCN2/CTGF) has anti-aging effects that protect articular cartilage from age-related degenerative changes. CCN2, CTS, WT
47  2013 CHIP enhances angiogenesis and restores cardiac function after infarction in transgenic mice. CHIP, MI, WT
48  2013 Epidermal overexpression of transgenic DeltaNp63 promotes type 2 immune and myeloid inflammatory responses and hyperplasia via NF-kappaB activation. ---
49  2013 HSPA12B attenuates cardiac dysfunction and remodelling after myocardial infarction through an eNOS-dependent mechanism. eNOS, MI, WT
50  2013 Human 5-HT₄receptor stimulation in atria of transgenic mice. WT
51  2013 β-Catenin signaling in hepatocellular cancer: Implications in inflammation, fibrosis, and proliferation. C/N, CON, GS, HCC, N/C, TAA, TMA, WT
52  2012 Characterizing antiviral mechanism of interleukin-32 and a circulating soluble isoform in viral infection. IL-32, rIL-32gamma, VSV
53  2012 Constitutive phosphorylation of inhibitor-1 at Ser67 and Thr75 depresses calcium cycling in cardiomyocytes and leads to remodeling upon aging. beta-AR, MyBP-C, PKA, PP1, Ser67, Thr35, WT
54  2012 Defective renal water handling in transgenic mice over-expressing human CD39/NTPDase1. WT
55  2012 In vivo magnetic resonance imaging of transgenic mice expressing human ferritin. MRI, myc-hFTH, WT
56  2012 Villin promoter-mediated transgenic expression of transient receptor potential cation channel, subfamily V, member 6 (TRPV6) increases intestinal calcium absorption in wild-type and vitamin D receptor knockout mice. BMD, Ca, TRPV6, VDR-KO, WT
57  2011 Abeta-42 deposition significantly increases the insolubility of synaptophysin in the brains of hAPPsw/hPS2m double transgenic mice. NSE
58  2011 APOE epsilon3 attenuates experimental autoimmune neuritis by modulating T cell, macrophage and Schwann cell functions. APOE, EAN, PNS, SC, WT
59  2011 Halofuginone has anti-proliferative effects in acute promyelocytic leukemia by modulating the transforming growth factor beta signaling pathway. APL, HF, NOD/SCID, PML-RARalpha, TGF-beta
60  2011 HSP75 protects against cardiac hypertrophy and fibrosis. HSPs
61  2011 Increased inflammatory signaling and lethality of influenza H1N1 by nuclear thioredoxin-1. GR, hTrx1, NLS, Trx-1, WT
62  2011 MCP-1-induced protein attenuates endotoxin-induced myocardial dysfunction by suppressing cardiac NF-кB activation via inhibition of IкB kinase activation. MCPIP, WT
63  2011 Overexpression of cAMP-response element modulator causes abnormal growth and development of the atrial myocardium resulting in a substrate for sustained atrial fibrillation in mice. AF
64  2011 Overexpression of Nrdp1 in the heart exacerbates doxorubicin-induced cardiac dysfunction in mice. Ad-GFP, DOX, ROS, STAT3, WT
65  2011 Polyol pathway and diabetic nephropathy revisited: Early tubular cell changes and glomerulopathy in diabetic mice overexpressing human aldose reductase. TonEBP, Wt
66  2011 Sost downregulation and local Wnt signaling are required for the osteogenic response to mechanical loading. MAR, WT
67  2011 The role of runt-related transcription factor 2 (Runx2) in the late stage of odontoblast differentiation and dentin formation. DSPP
68  2010 Absence of mitochondrial toxicity in hearts of transgenic mice treated with abacavir. ABC, KO, LV, LVEDD, MCAT, mtDNA, NRTI, WT
69  2010 Accelerated liver regeneration and hepatocarcinogenesis in mice overexpressing serine-45 mutant beta-catenin. DEN, GS, HCC, PH, WT
70  2010 Chemokine CXCL14/BRAK transgenic mice suppress growth of carcinoma cell transplants. [corrected] HNSCC
71  2010 Effects of increased iron intake during the neonatal period on the brain of adult AbetaPP/PS1 transgenic mice. WT
72  2010 Forced expression of programmed death-1 gene on T cell decreased the incidence of type 1 diabetes. PD-1, STZ, WT
73  2010 Genomic profiling of messenger RNAs and microRNAs reveals potential mechanisms of TWEAK-induced skeletal muscle wasting in mice. miRs
74  2010 Losartan reduces mortality in a genetic model of heart failure. CSQ
75  2010 Postischemic cardiac recovery in heme oxygenase-1 transgenic ischemic/reperfused mouse myocardium. AF, AoP, CF, CO, HO-1, KO, LV, NTG, RV
76  2010 Transgenic cardiac-targeted overexpression of human thymidylate kinase. AZT, LV, mtDNA, NA, WT
77  2009 Dietary fish oil is antihypertrophic but does not enhance postischemic myocardial function in female mice. CTR, FO, PUFA, RPP, WT
78  2009 Dilated cardiomyopathy in transgenic mice expressing HIV Tat. FVB, HR, LVEDP, LVSP
79  2009 Expression of GAT1 in male reproductive system and its effects on reproduction in mice. GABA, HE, WT
80  2009 Mechanical properties of intact single fibres from wild-type and MLC/mIgf-1 transgenic mouse muscle. WT
81  2009 Nicotinamide mononucleotide adenylyltransferase expression in mitochondrial matrix delays Wallerian degeneration. NAD, NMNAT
82  2009 Overexpression of myosin phosphatase reduces Ca(2+) sensitivity of contraction and impairs cardiac function. MP, MYPT2
83  2009 Role of nuclear unphosphorylated STAT3 in angiotensin II type 1 receptor-induced cardiac hypertrophy. AT1R, t-STAT3, U-STAT3
84  2009 Transgenic mitochondrial superoxide dismutase and mitochondrially targeted catalase prevent antiretroviral-induced oxidative stress and cardiomyopathy. CM, LV, MCAT, WT
85  2008 Altered cellular immunity in transgenic mice with T cell-specific expression of human D4-guanine diphosphate-dissociation inhibitor (D4-GDI). D4-GDI, GDP, LMs
86  2008 High levels of serum IL-18 promote cartilage loss through suppression of aggrecan synthesis. OA, WT
87  2008 Overexpression/enhanced kinase activity of BCR/ABL and altered expression of Notch1 induced acute leukemia in p210BCR/ABL transgenic mice. ALL, CISs, CML
88  2008 The protective role of transferrin in Müller glial cells after iron-induced toxicity. CRALBP, LDH, MG, RIA, Tf, WT
89  2008 [Heat shock protein 27 attenuated doxorubicin-induced myocardial damage by reducing cardiomyocyte apoptosis, mitochondria damage and protein carbonylation]. CHF, DOX, HSP27, WT
90  2007 A diet high in omega-3 fatty acids does not improve or protect cognitive performance in Alzheimer's transgenic mice. AD, APP, NT
91  2007 Active immunization against Alzheimer's beta-amyloid peptide using phage display technology. AbetaP, AD
92  2007 Alterations in myostatin expression are associated with changes in cardiac left ventricular mass but not ejection fraction in the mouse. MCK, Mst
93  2007 Establishment of a poliovirus oral infection system in human poliovirus receptor-expressing transgenic mice that are deficient in alpha/beta interferon receptor. PV
94  2007 Glycogen synthase kinase-3alpha reduces cardiac growth and pressure overload-induced cardiac hypertrophy by inhibition of extracellular signal-regulated kinases. GSK-3, nTg, PKCepsilon, TAC
95  2007 Over-expression of heat shock protein 27 attenuates doxorubicin-induced cardiac dysfunction in mice. HF, HSP27, WT
96  2006 Antiretroviral nucleosides, deoxynucleotide carrier and mitochondrial DNA: evidence supporting the DNA pol gamma hypothesis. DNC, LV, mt, NRTIs, WT
97  2006 Differential expression of MMPs and TIMPs in moderate and severe heart failure in a transgenic model. HF, MMPs, WT
98  2006 Up-regulation of the inward rectifier K+ current (I K1) in the mouse heart accelerates and stabilizes rotors. DF, VT, WT
99  2005 AMP-activated protein kinase alpha2 activity is not essential for contraction- and hyperosmolarity-induced glucose transport in skeletal muscle. AICAR, AMPK, EDL
100  2005 Enhanced cardiac function in mice overexpressing protein phosphatase Inhibitor-2. PLB, PP, PP1, WT