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Abbreviation : TIMP
Long Form : tissue inhibitor of metalloproteinase
No. Year Title Co-occurring Abbreviation
2022 Isolation, Expansion, and Characterization of Placenta Originated Decidua Basalis-Derived Mesenchymal Stromal Cells. DB, GF, IL, MSCs
2022 Micro-fragmented adipose tissue regulated the biological functions of osteoarthritis synoviocytes by upregulating MiR-92a-3p expression. CCL, ELISA, HA, IL, MF, MMP, OA, PGE2, qRT-PCR, TNF-alpha
2021 22-O-(N-Boc-L-glycine) ester of renieramycin M inhibits migratory activity and suppresses epithelial-mesenchymal transition in human lung cancer cells. 22-Boc-Gly-RM, EMT
2021 A dynamic nomogram for predicting diabetic macular edema in type 2 diabetes patients based on plasma cytokines. AUC, DME, DME, PDGF, T2DM, VEGFR
2021 Abnormal B-cell development in TIMP-deficient bone marrow. BM, LSK
2021 Activated matrix metalloproteinase 8 in serum predicts severity of acute pancreatitis. aMMP-8, HNE, MMPs, MPO, ROC, SAP
2021 Alteration of Extracellular Matrix Components in the Anterior Pituitary Gland of Neonatal Rats Induced by a Maternal Bisphenol A Diet during Pregnancy. BPA, ECM, FS, MMP
2021 An exploratory study of associations with spontaneous preterm birth in primigravid pregnant women with a normal cervical length. MMP, sPTB
2021 Antirheumatic treatment is associated with reduced serum Syndecan-1 in Rheumatoid Arthritis. DMARDs, EG, MMP-9, MTX, RA, TNFi
10  2021 Application of TGF-beta1, TIMP-1 and TIMP-2 small interfering RNAs can alleviate CCl4-induced hepatic fibrosis in rats by rebalancing Th1/Th2 cytokines. si, Th
11  2021 Assessment of serum concentrations of matrix metalloproteinase 1, matrix metalloproteinase 2 and tissue inhibitors of metalloproteinases 1 in atopic dermatitis in correlation with disease severity and epidermal barrier parameters. AD, EASI, MMPs, TEWL
12  2021 Autologous Adipose-Derived Mesenchymal Stem Cells Combined with Shockwave Therapy Synergistically Ameliorates the Osteoarthritic Pathological Factors in Knee Joint. ADSCs, BMP, OA, PRG, SW, TSG
13  2021 Budesonide repairs decreased barrier integrity of eosinophilic nasal polyp epithelial cells caused by PM2.5. eos-CRSwNP, IL, NPs, PM2.5, qPCR, TER, TJ
14  2021 Changes in Inflammatory Cytokines in Saliva after Non-Surgical Periodontal Therapy: A Systematic Review and Meta-Analysis. IL, MMP, OHI, PGE2, SRP, TNF
15  2021 Comparison of Gene Expression of Inflammation- and Fibrosis-Related Factors Between the Anterior and Posterior Capsule in Patients With Rotator Cuff Tear and Shoulder Stiffness. MMP
16  2021 Comparison of the Cytokine Profile in Mesenchymal Stem Cells from Human Adipose, Umbilical Cord, and Placental Tissues. A-MSCs, IGFBP, IL, MSCs, pMSCs, UC-MSCs
17  2021 Comprehensive analysis of expression, prognosis and immune infiltration for TIMPs in glioblastoma. DSS, ECM, GBM, MMP, OS
18  2021 Coxsackievirus A2 Leads to Heart Injury in a Neonatal Mouse Model. AST, CTGF, CVA2, HFMD, IL-1beta, LDH, MAPK, MCP-1, MMP, NF-kappaB, PI3K, TNF-alpha
19  2021 Dermal fibroblasts cultured from donors with type 2 diabetes mellitus retain an epigenetic memory associated with poor wound healing responses. DF, T2DM, TNF-alpha
20  2021 Diagnostic values of MMP-7, MMP-9, MMP-11, TIMP-1, TIMP-2, CEA, and CA19-9 in patients with colorectal cancer. CA, CEA, CRC, MMP
21  2021 Differential Expression of MMP2 and TIMP2 in Peripheral Blood Mononuclear Cells After Roux-en-Y Gastric Bypass. BMI, CG, ECM, FM, MMP, PBMCs, RNA, RYBG, SG
22  2021 Diverse effects of pan-ROCK and ROCK2 inhibitors on 2 D and 3D cultured human trabecular meshwork (HTM) cells treated with TGFbeta2. ECM, HTM, MMP, Rip, ROCK, TEER
23  2021 Effect and mechanism of vitamin D activation disorder on liver fibrosis in biliary atresia. BA, Col, HSCs, MMP, TGF
24  2021 Effect of anti-tuberculosis treatment on the systemic levels of tissue inhibitors of metalloproteinases in tuberculosis - Diabetes co-morbidity. ATT, NDM, TB, TB-DM
25  2021 Effect of hTIMP-1 overexpression in human umbilical cord mesenchymal stem cells on the repair of pancreatic islets in type-1 diabetic mice. EGFP, hUCMSCs, MSCs, T1DM
26  2021 Effect of sugar metabolite methylglyoxal on equine lamellar explants: An ex vivo model of laminitis. HE, MG, MMP
27  2021 Effects of (-)-Loliolide against Fine Dust Preconditioned Keratinocyte Media-Induced Dermal Fibroblast Inflammation. FD, HDF, MMP, NF
28  2021 Effects of lumican expression on the apoptosis of scleral fibroblasts: In vivo and in vitro experiments. MMP
29  2021 Elevated Plasma Levels of Matrix Metalloproteinase-3 and Tissue-Inhibitor of Matrix Metalloproteinases-1 Associate With Organ Dysfunction and Mortality in Sepsis. AKI, ARDS, MMP, OR
30  2021 Enhanced transforming growth factor-beta signaling and fibrosis in the pectoralis major muscle of broiler chickens affected by wooden breast myopathy. ECM, MMP, PM, TGF-beta, WB
31  2021 Establishment of appropriate glaucoma models using dexamethasone or TGFβ2 treated three-dimension (3D) cultured human trabecular meshwork (HTM) cells. alpha-SMA, Col, DEX, ECM, FN, HTM, MMP, TEER, TM
32  2021 Fibrosis as a result of polyhexamethylene guanide exposure in cultured Statens Seruminstitut Rabbit Cornea (SIRC) cells. alpha-SMA, HO-1, MMP, MTT, PCR, PHMG, SIRC, TGF-beta
33  2021 Genetic variants of tissue inhibitors of matrix metalloproteinase 1 (rs4898) and 2 (rs8179090) in diverticulosis. ---
34  2021 HBV induces liver fibrosis via the TGF-beta1/miR-21-5p pathway. col1a1, HBV, miR, SMA
35  2021 High cyclic tensile stress disrupts the extracellular matrix in human chondrocyte by F-actin cytoskeletal polymerization and reactive oxygen species production. CHs, CTS, ECM, MMP, NAC, ROS
36  2021 In vitro and in vivo tenocyte-protective effectiveness of dehydroepiandrosterone against high glucose-induced oxidative stress. DHEA, DHEA group, HG, IL-6, LG, MMP, mRNA, NOX, ROS
37  2021 MicroRNA-146b-5p promotes atrial fibrosis in atrial fibrillation by repressing TIMP4. AF, hiPSC-aCMs, MI, MMP
38  2021 MiR-130a-3p Alleviates Liver Fibrosis by Suppressing HSCs Activation and Skewing Macrophage to Ly6Clo Phenotype. HSCs, LV, MAPK, miRNAs, MMP, S. japonicum, TGFBR
39  2021 Modulation of peritumoral fibroblasts with a membrane-tethered tissue inhibitor of metalloproteinase (TIMP) for the elimination of cancer cells. ECM, GPI
40  2021 Modulation of the Physical Properties of 3D Spheroids Derived from Human Scleral Stroma Fibroblasts (HSSFs) with Different Axial Lengths Obtained from Surgical Patients. Col, ECM, ER, FN, HIF-1A, HSSFs, IHC, LOX, MMP
41  2021 Ocular TGF-β, Matrix Metalloproteinases, and TIMP-1 Increase with the Development and Progression of Diabetic Retinopathy in Type 2 Diabetes Mellitus. AH, DM, DR, MMPs, NPDR, PDR
42  2021 Oncostatin M promotes infarct repair and improves cardiac function after myocardial infarction. CCR, IL, MI, MMP, OSM
43  2021 Prognostic Value of Multiple Circulating Biomarkers for 2-Year Death in Acute Heart Failure With Preserved Ejection Fraction. GDF15, HFpEF, hsTnT, IDI, MMP, NRI, SVM, TNF-alpha
44  2021 Prostaglandin-E2 receptor-4 stimulant rescues cardiac malfunction during myocarditis and protects the heart from adverse ventricular remodeling after myocarditis. DCM, EP4, LV, MMP
45  2021 Racial difference in atrial size and extracellular matrix homeostatic response to hypertension: Is this a potential mechanism of reduced atrial fibrillation in African Americans? AA, AF, ECM, HFpEF, HTN, LVH, MMP
46  2021 Repeated exposure of house dust mite induces progressive airway inflammation in mice: Differential roles of CCL17 and IL-13. AHR, BAL, HDM, mAbs
47  2021 Role of matrix metalloproteinases and their tissue inhibitors in the pathological mechanisms underlying maxillofacial cystic lesions. MMPs
48  2021 Salivary glands of fetuses are adversely affected by artificial food colorings in rats. anti-MMP2
49  2021 Schwann cells promote prevascularization and osteogenesis of tissue-engineered bone via bone marrow mesenchymal stem cell-derived endothelial cells. AECs, BM-MSCs, IECs, IOBs, SC-CM, SCs, TEBGs, VEGF
50  2021 Screening of the Drug-Induced Effects of Prostaglandin EP2 and FP Agonists on 3D Cultures of Dexamethasone-Treated Human Trabecular Meshwork Cells. alpha-SMA, ATF6, CHOP, Col, DEX, ECM, ER, FITC, FN, GRP, HTM, IRE1, MMP, OMD, PGF2 alpha, TEER
51  2021 Serum tissue inhibitor of MMP-1 levels at any moment of the first week of spontaneous intracerebral hemorrhage may predict early mortality. SIH
52  2021 The Combination of Electroacupuncture and Massage Therapy Alleviates Myofibroblast Transdifferentiation and Extracellular Matrix Production in Blunt Trauma-Induced Skeletal Muscle Fibrosis. CTGF, EA
53  2021 The EP2 agonist, omidenepag, alters the physical stiffness of 3D spheroids prepared from human corneal stroma fibroblasts differently depending on the osmotic pressure. AQP1, Col, ECM, ER, FITC, FN, hCSFs, MMP, OMD, SEM, TEER
54  2021 The Imbalance of MMP-2/TIMP-2 and MMP-9/TIMP-1 Contributes to Collagen Deposition Disorder in Diabetic Non-Injured Skin. HDFs, MMP
55  2021 The prognostic and diagnostic value of tissue inhibitor of metalloproteinases gene family and potential function in gastric cancer. AUC, GC, GSEA
56  2021 The role of Smad1/5 in mantle immunity of the pearl oyster Pinctada fucata martensii. BMP-2, Cu,Zn-SOD, IL-17, LITAF, MMP, NF-kappaB
57  2021 The Role of the Metzincin Superfamily in Prostate Cancer Progression: A Systematic-Like Review. ADAM, MMP, MT-MMP
58  2021 Treatment of Sorsby fundus dystrophy with anti-tumor necrosis factor-alpha medication. OCT, TNF-alpha
59  2021 Uniportal video-assisted thoracic surgery for major lung resection is associated with less immunochemokine disturbances than multiportal approach. IGFBP, MMP, VATS
60  2021 Wood Smoke Extract Promotes Extracellular Matrix Remodeling in Normal Human Lung Fibroblasts. ECM, MMP, NHLFs, PAHs, TGF, WS, WSE
61  2020 Aesculetin Attenuates Alveolar Injury and Fibrosis Induced by Close Contact of Alveolar Epithelial Cells with Blood-Derived Macrophages via IL-8 Signaling. BALF, CXCR2, IL, mCM, MMP, PHMG, TNF
62  2020 An Anthocyanin-Enriched Extract from Vaccinium uliginosum Improves Signs of Skin Aging in UVB-Induced Photodamage. ERK, HPLC, JNK, MMP, TEWL, UVB
63  2020 Associations of TIMP-3 Genetic Polymorphisms with EGFR Statuses and Cancer Clinicopathologic Development in Lung Adenocarcinoma Patients. aOR, CI, EGFR, LADC, MMPs
64  2020 Beneficial effects of N-acetylcysteine on protease-antiprotease balance in attenuating bleomycin-induced pulmonary fibrosis in rats. AECs, MMP, NAC, TGF-beta1
65  2020 Cigarette Smoke Extract Stimulates MMP-2 Production in Nasal Fibroblasts via ROS/PI3K, Akt, and NF-kappaB Signaling Pathways. CSE, MMP, ROS
66  2020 ClassC1 decoy oligodeoxynucleotide inhibits profibrotic genes expression in rat hepatic stellate cells. HSC, ODNs, TGF
67  2020 Concerted actions by MMPs, ADAMTS and serine proteases during remodeling of the cartilage callus into bone during osseointegration of hip implants. NE, OA, PR3, SLPI
68  2020 CpG postconditioning after reperfused myocardial infarction is associated with modulated inflammation, less apoptosis, and better left ventricular function. CpG, LAD, LV, MHC, MI, MMP, MMP-8, TLR9
69  2020 Cytokines, Angiogenesis, and Extracellular Matrix Degradation are Augmented by Oxidative Stress in Endometriosis. COX, ECM, IL, MMP, NF-kappaB, OS, VEGF
70  2020 Decreased Collagen Type I is Associated with Increased Metalloproteinase-2 Activity and Protein Expression of Leptin in the Myocardium of Obese Rats. ---
71  2020 Development of Postoperative Pain in Patients with End-Stage Knee Osteoarthritis Is Associated with Upregulation of Genes Related to Extracellular Matrix Degradation, Inflammation, and Apoptosis Measured in the Peripheral Blood before Knee Surgery. COX, DN4, IL, OA, PBMCs, ROC, TNF, VAS, WOMAC
72  2020 DNA methylation of MMPs and TIMPs in atherothrombosis process in carotid plaques and blood tissues. DNAm, ISC-1, ISC-2, MMP
73  2020 Effect of prostaglandin analogs: Latanoprost, bimatoprost, and unoprostone on matrix metalloproteinases and their inhibitors in human trabecular meshwork endothelial cells. MMPs, TM
74  2020 Effects of a Matrix Metalloproteinase Inhibitor-Eluting Stent on In-Stent Restenosis. ISR, MMP, VSMCs
75  2020 Effects of exercise training on renal interstitial fibrosis and renin-angiotensin system in rats with chronic renal failure. ACE, MMP, RAS, TGF-beta1
76  2020 Evaluation of extracellular matrix protein expression and apoptosis in the uterosacral ligaments of patients with or without pelvic organ prolapse. Bax, Bcl-2, ECM, ER, IHC, MMP, POP, USL
77  2020 Evaluation of significant gene expression changes in congenital and acquired cholesteatoma. EGFR, MMP, SPSS
78  2020 Improvement of Impaired Motor Functions by Human Dental Exfoliated Deciduous Teeth Stem Cell-Derived Factors in a Rat Model of Parkinson's Disease. CNS, IGFBP-6, IPA, PD, SHED, SHED-CM, TGF-1
79  2020 Inhibiting the NLRP3 inflammasome with MCC950 ameliorates retinal neovascularization and leakage by reversing the IL-1β/IL-18 activation pattern in an oxygen-induced ischemic retinopathy mouse model. Ang-2, ASC, CARD, CAS1, IL, MMP, NLRP3, OIR, PDGF-B, PDGFR-beta, RNV, VEGF, VEGFR
80  2020 Insulin-like growth factor-binding protein 3 inhibits angiotensin II-induced aortic smooth muscle cell phenotypic switch and matrix metalloproteinase expression. ACTA2, Ang, AoSMC, IGFBP3, MMP, MYH11, SPP1, TAD
81  2020 Interplay between perivascular and perineuronal extracellular matrix remodelling in neurological and psychiatric diseases. CNS, ECM, MMPs
82  2020 Interstitial changes after reperfused myocardial infarction in swine: morphometric and genetic analysis. ECM, MI
83  2020 Irisin Recovers Osteoarthritic Chondrocytes In Vitro. ERK, hOAC, IL, iNOS, JNK, MAPK, MMP, NF-kappaB
84  2020 Levels of Gene Expression of Immunological Biomarkers in Peri-Implant and Periodontal Tissues. IL, MMP, TNF-alpha
85  2020 Matrix metalloproteinases regulate ECM accumulation but not larval heart growth in Drosophila melanogaster. ECM
86  2020 MiR-95-5p involves in the migration and invasion of trophoblast cells by targeting low density lipoprotein receptor-related protein 6. LRP6, miR, MMP, PE, qRT-PCR, WB
87  2020 Modulation of Immune Responses by Platelet-Derived ADAM10. ADAM, MMP
88  2020 Molecular mechanism of the effect of angiopoietin-like protein 8 on the proliferation, invasion and migration of placental trophoblasts in preeclampsia. ANGPTL8, MMP, PE, si
89  2020 Morphometric and Molecular Muscle Remodeling after Passive Stretching in Elderly Female Rats. COL1, Col3, TGF-beta1, TNF-alpha
90  2020 Nebivolol Prevents Up-Regulation of Nox2/NADPH Oxidase and Lipoperoxidation in the Early Stages of Ethanol-Induced Cardiac Toxicity. MMP, SOD, TBARS
91  2020 Novel biomarkers of acute kidney injury in children: an update on recent findings. AKI, IGFBP, IL, NGAL
92  2020 Protective effects of desipramine on alveolar bone in experimental periodontitis. COX, IL, iNOS, MMP
93  2020 Resveratrol inhibits the tumor migration and invasion by upregulating TET1 and reducing TIMP2/3 methylation in prostate carcinoma cells. 5hmC, 5mC, PCa, RES, TET1
94  2020 Role of biomarkers of cardiac remodeling, myofibrosis, and inflammation in assessment of disease severity in euvolemic patients with chronic stable heart failure. CHF, GDF, NT-proBNP, sST2
95  2020 SARS-CoV-2 induces transcriptional signatures in human lung epithelial cells that promote lung fibrosis. ACE, ADAM, AGT, COVID-19, CTGF, FN, SARS, TMPRSS, VEGF
96  2020 Shear Stress and Aortic Strain Associations With Biomarkers of Ascending Thoracic Aortic Aneurysm. miRNA, MMP, TAWSS, WSS
97  2020 Synovial fluid fingerprinting in end-stage knee osteoarthritis: a novel biomarker concept. AUC, esOA, IP-10, MCP, OA, PLS-DA, ROC, SF, TGF
98  2020 The Identification of Immune-Related Plasma Proteins Associated with Spontaneous Preterm Delivery and Intra-Amniotic Infection in Women with Premature Cervical Dilation or an Asymptomatic Short Cervix. AF, AUC, ELISA, IL, MMP, SPTD
99  2020 Three Tiaobu Feishen formulae reduces cigarette smoke-induced inflammation in human airway epithelial cells. AP, BJF, BYF, CSE, IL, LPS, MAPK, MMP, NF, PPAR, SOD, STAT, TBFS, TNF, YZF
100  2020 Tissue Inhibitor of Metalloproteinase (TIMP) Peptidomimetic as an Adjunctive Therapy for Infectious Keratitis. alpha-SMA, MMP-9