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Abbreviation : TRAP
Long Form : telomeric repeat amplification protocol
No. Year Title Co-occurring Abbreviation
2022 Monitoring Telomere Maintenance During Regeneration of Annelids. FISH, TRF
2022 New Genetic Bomb Trigger: Design, Synthesis, Molecular Dynamics Simulation, and Biological Evaluation of Novel BIBR1532-Related Analogs Targeting Telomerase against Non-Small Cell Lung Cancer. ---
2022 Sensitive naked-eye detection of telomerase activity based on exponential amplification reaction and lateral flow assay. EXPAR, LFR-EXPAR
2022 Single-molecule displacement assay reveals strong binding of polyvalent dendrimer ligands to telomeric G-quadruplex. smDA
2022 The telomere maintenance mechanism spectrum and its dynamics in gliomas. ALT, TMM
2021 Cost-Effective Trap qPCR Approach to Evaluate Telomerase Activity: an Important Tool for Aging, Cancer, and Chronic Disease Research. ---
2021 Detection of Urothelial Bladder Cancer Based on Urine and Tissue Telomerase Activity Measured by Novel RT-TRAP-2PCR Method. BCa, NMIBC, TA
2021 hTERT Downregulation Attenuates Resistance to DOX, Impairs FAK-Mediated Adhesion, and Leads to Autophagy Induction in Breast Cancer Cells. FAK, hTERT
2021 IL-15 Upregulates Telomerase Expression and Potently Increases Proliferative Capacity of NK, NKT-Like, and CD8 T Cells. anti-TERT, CFSE, IL-15, NK, PBMCs
10  2021 Nonradioactive direct telomerase activity detection using biotin-labeled primers. DTA
11  2021 Telomerase Activity Analysis In Urine Sediment for Bladder Cancer. ---
12  2021 Telomere Length in Valve Tissue Is Shorter in Individuals With Aortic Stenosis and in Calcified Valve Areas. AS, TL, TRF
13  2020 A CRISPR-driven colorimetric code platform for highly accurate telomerase activity assay. FN, IC, TL-LFA
14  2020 Adiponectin attenuates the premature senescence of vascular smooth muscle cells induced by high glucose through mTOR signaling pathway. SA-beta-gal, VSMCs
15  2020 Effect of bisphenols on telomerase expression and activity in breast cancer cell lines. BPA, BPF, BPS, ER, RT-qPCR, RTL
16  2020 Expression Pattern of Telomerase Reverse Transcriptase (hTERT) Variants and Bcl-2 in Peripheral Lymphocytes of Systemic Lupus Erythematosus Patients. SLE
17  2020 Lymphopenia in primary Sjogren's syndrome is associated with premature aging of naive CD4+ T cells. pSS, SABG, TREC, TRECs
18  2020 Reduced telomere shortening in lifelong trained male football players compared to age-matched inactive controls. BP, FISH, MNC, PCR, RHR, TRF
19  2020 Targeting G-quadruplex DNA with synthetic dendritic peptide: modulation of the proliferation of human cancer cells. ---
20  2019 Amplification-free and direct fluorometric determination of telomerase activity in cell lysates using chimeric DNA-templated silver nanoclusters. AgNCs
21  2019 Chidamide-induced ROS accumulation and miR-129-3p-dependent cell cycle arrest in non-small lung cancer cells. HDACi, hTERT, NAC, NSCLC, ROS, TS
22  2019 Droplet Digital TRAP (ddTRAP): Adaptation of the Telomere Repeat Amplification Protocol to Droplet Digital Polymerase Chain Reaction. ddTRAP, PCR
23  2019 Nonradioactive and Radioactive Telomerase Assays for Detecting Diminished Telomerase Activity in Cancer Cells after Treatment with Retinoid. ---
24  2019 Telomerase Inhibitor TMPyP4 Alters Adhesion and Migration of Breast-Cancer Cells MCF7 and MDA-MB-231. ---
25  2019 Telomerase stability and evaluation of real-time telomeric repeat amplification protocol. NMR
26  2019 The Anticancer Efficacy of Platinum Azidothymidin on Hepatocellular Carcinoma Via Affecting the Telomerase and the BcL-2 Genes Expression. AZT, ELISA
27  2018 Activated carbon N-acetylcysteine microcapsule protects against nonalcoholic fatty liver disease in young rats via activating telomerase and inhibiting apoptosis. ACNAC, ALT, AST, FDA, HFD, NAFLD
28  2018 Design, Synthesis and Pharmacological Evalution of 1,3,4-Oxadiazole Derivatives as Collapsin Response Mediator Protein 1 (CRMP 1) Inhibitors. CRMP 1
29  2017 Advances in the detection of telomerase activity using isothermal amplification. PCR
30  2017 Arylsulfanyl groups - Suitable side chains for 5-substituted 1,10-phenanthroline and nickel complexes as G4 ligands and telomerase inhibitors. CD, FID, Phen-Ni
31  2017 Assessing Telomerase Activities in Mammalian Cells Using the Quantitative PCR-Based Telomeric Repeat Amplification Protocol (qTRAP). qTRAP, qTRAP
32  2017 Catalytic assembly of DNA nanostructures on a nanoporous gold array as 3D architectures for label-free telomerase activity sensing. ELISA, LOD, MG, NPGA, PCR, SERS, XPS
33  2017 Enterolactone Reduces Telomerase Activity and The Level of Its Catalytic Subunit in Breast Cancer Cells. END, ENL, hTERT, PCR
34  2017 Highly Sensitive Telomerase Assay Insusceptible to Telomerase and Polymerase Chain Reaction Inhibitors for Cervical Cancer Screening Using Scraped Cells. aPCR
35  2017 Quantitative Determination of Telomerase Activity by Combining Fluorescence Correlation Spectroscopy with Telomerase Repeat Amplification Protocol. FCS
36  2017 [Effect of telomerase activation on biological behaviors of neural stem cells in rats with hypoxic-ischemic insults]. LDH, OGD, TERT
37  2016 DHA-enriched fish oil upregulates cyclin-dependent kinase inhibitor 2A (P16INK) expression and downregulates telomerase activity without modulating effects of PPARgamma Pro12Ala polymorphism in type 2 diabetic patients: A randomized, double-blind, placebo-controlled clinical trial. DHA, PBMC, RT-PCR
38  2016 G-Quadruplex ligands: Potent inhibitors of telomerase activity and cell proliferation in Plasmodium falciparum. ---
39  2016 High-throughput identification of telomere-binding ligands based on the fluorescence regulation of DNA-copper nanoparticles. CD, cDNA, dsDNA
40  2016 Model-Guided Interface Probe Arrangement for Sensitive Protein Detection. AuNPs
41  2016 Telomerase activity in non-small cell lung cancer. NSCLC
42  2016 Telomerase repeat amplification protocol (TRAP) activity upon recombinant expression and purification of human telomerase in a bacterial system. ---
43  2016 Telomerase Repeated Amplification Protocol (TRAP). PCR, TIF, TRF
44  2016 Telomere Dysfunction Induced Foci (TIF) Analysis. TIF, TIFs, TRF
45  2016 Telomere Restriction Fragment (TRF) Analysis. TIF, TRF, TRF
46  2015 A PCR-free fluorescence strategy for detecting telomerase activity via double amplification strategy. MB, tDNA, TS
47  2015 Allium telomeres unmasked: the unusual telomeric sequence (CTCGGTTATGGG)n is synthesized by telomerase. FISH, TERT
48  2015 Detection of telomerase activity using microchip electrophoresis. HPMC, PCR, PEO
49  2015 Effects of bleomycin A5 on caspase-3, P53, bcl-2 expression and telomerase activity in vascular endothelial cells. ---
50  2015 Effects of silymarin and silymarin-doxorubicin applications on telomerase activity of human hepatocellular carcinoma cell line HepG2. HCC, TBARS
51  2015 Exonuclease I manipulating primer-modified gold nanoparticles for colorimetric telomerase activity assay. Exo I, GNPs
52  2015 Expression Pattern of Alternative Splicing Variants of Human Telomerase Reverse Transcriptase (hTERT) in Cancer Cell Lines Was not Associated with the Origin of the Cells. hTERT
53  2015 Human endometrial epithelial telomerase is important for epithelial proliferation and glandular formation with potential implications in endometriosis. EEC, IHC, MPA, TA, TL
54  2015 MST-312 induces G2/M cell cycle arrest and apoptosis in APL cells through inhibition of telomerase activity and suppression of NF-kappaB pathway. APL, EGCG, PBMCs
55  2015 Non-radioactive assay methods for the assessment of telomerase activity and telomere length. ---
56  2015 PCDH10 Interacts With hTERT and Negatively Regulates Telomerase Activity. hTERT, PCDH10
57  2015 Potent Human Telomerase Inhibitors: Molecular Dynamic Simulations, Multiple Pharmacophore-Based Virtual Screening, and Biochemical Assays. MDS
58  2015 Recurrent TERT promoter mutations identified in a large-scale study of multiple tumour types are associated with increased TERT expression and telomerase activation. GIST, RT-qPCR, TERT
59  2015 Targeting Human Telomerase Reverse Transcriptase by a Simple siRNA Expression Cassette in HepG2 Cells. HCC, hTERT, PCR, PI, RT, SEC, siRNAs
60  2015 The addition of a spin column step in the telomeric repeat application protocol removes telomerase inhibitors. PCR
61  2015 TTAGG-repeat telomeres and characterization of telomerase in the beet armyworm, Spodoptera exigua (Lepidoptera: Noctuidae). TER, TERT
62  2014 Anti-proliferative effects of Atractylis lancea (Thunb.) DC. via down-regulation of the c-myc/hTERT/telomerase pathway in Hep-G2 cells. hTERT
63  2014 Anticancer activity for targeting telomeric G-quadruplex and antiangiogenesis of a novel Ru(II)-Se complex. HUVEC, PCR, Phen-Se, Ru-Se
64  2014 Antisense oligodeoxynucleotide against human telomerase reverse transcriptase inhibits the proliferation of Eca-109 esophageal carcinoma cells. AS-ODNs, hTERT, hTR, PS-ASODN
65  2014 Assessment of DNA damage and telomerase activity in exfoliated urinary cells as sensitive and noninvasive biomarkers for early diagnosis of bladder cancer in ex-workers of a rubber tyres industry. ---
66  2014 Expression of HPV-16 E6 protein and p53 inactivation increases the uterine cervical cancer invasion. ---
67  2014 Quantitative telomerase enzyme activity determination using droplet digital PCR with single cell resolution. ddPCR, ddTRAP
68  2014 Telomerase activity analyzed with TRAP in situ provides additional information in effusions remaining equivocal after immunocytochemistry and hyaluronan analysis. ---
69  2014 Telomerase activity in the various regions of mouse brain: non-radioactive telomerase repeat amplification protocol (TRAP) assay. ---
70  2014 Telomerase inhibition abolishes the tumorigenicity of pediatric ependymoma tumor-initiating cells. ALT, TICs
71  2014 Telomere 1 (POT1) gene expression and its association with telomerase activity in colorectal tumor samples with different pathological features. ---
72  2013 A comparative study of telomerase activity and cytologic diagnosis in malignant ascites. RTQ-TRAP
73  2013 Aging phenotypes in cultured normal human mammary epithelial cells are correlated with decreased telomerase activity independent of telomere length. flowFISH, HMEC, RTL
74  2013 Aspirin inhibits human telomerase activation in unstable carotid plaques. ELISA, hTERT, PMNs, RT-PCR
75  2013 Assessment and quantification of telomerase enzyme activity. PCR, Q-TRAP
76  2013 Development of a novel telomerase assay using the PPDK-luciferin-luciferase detection system. CV, PCR, PLLBA, PPDK, S/N
77  2013 Effects of gamma irradiation on cell cycle, apoptosis and telomerase activity in p53 wild-type and deficient HCT116 colon cancer cell lines. ---
78  2013 Graphene-mesoporous silica-dispersed palladium nanoparticles-based probe carrier platform for electrocatalytic sensing of telomerase activity at less than single-cell level. PCR
79  2013 Impact of Hepatitis C Virus (HCV) infection on biomolecular markers influencing the pathogenesis of bladder cancer. BC, FGFR3, HCV, Rb, SCCs
80  2013 Label-free, PCR-free chip-based detection of telomerase activity in bladder cancer cells. PCR
81  2013 Progenitor cell line (hPheo1) derived from a human pheochromocytoma tumor. BMP4, hTERT, NGF, PNMT
82  2013 Ruthenium(II) polypyridyl complexes as G-quadruplex inducing and stabilizing ligands in telomeric DNA. FRET, PCR
83  2013 SSEA-1 isolates human endometrial basal glandular epithelial cells: phenotypic and functional characterization and implications in the pathogenesis of endometriosis. TLs
84  2013 Targeting telomeric G-quadruplexes with the ruthenium(II) complexes [Ru(bpy)(2)(ptpn)](2+) and [Ru(phen)(2)(ptpn)](2+). CD, FRET, PCR
85  2013 Telomere length modulation in human astroglial brain tumors. AA, GBM, LGA, NBT, TANKs-PARP, TRF
86  2013 The beta-carboline alkaloid harmine inhibits telomerase activity of MCF-7 cells by down-regulating hTERT mRNA expression accompanied by an accelerated senescent phenotype. ---
87  2013 The effect of hydroxycamptothecin and pingyangmycin on human squamous cell carcinoma of the tongue. HCPT, PYM
88  2013 Using PCR coupled to PAGE for detection and semiquantitative evaluation of telomerase activity. ---
89  2013 [Expression of telomerase activity and its related genes in the marrow hemopoietic stem cells of children with aplastic anemia]. AA
90  2012 Genomic amplification of the human telomerase gene (hTERC) associated with human papillomavirus is related to the progression of uterine cervical dysplasia to invasive cancer. CIN, FISH, HPV, hTERT, IHC
91  2012 Improved inhibition of telomerase by short twisted intercalating nucleic acids under molecular crowding conditions. TINA
92  2012 Prostate-specific antigen gene expression and telomerase activity in breast cancer patients: possible relationship to steroid hormone receptors. PSA, RTA
93  2012 Telomerase activity alterations in sequential passages of mouse embryonic stem cells. TA
94  2012 The effect of silymarin on telomerase activity in the human leukemia cell line K562. ---
95  2012 [Clinical significance of telomerase activity detection of myeloid element in immune related hematocytopenia]. BMMNC, FcgammaIIR, IF, IL-17A, IRH/IRP, MR, TA
96  2011 Change of telomerase activity in peripheral whole blood of head and neck squamous cell carcinoma patients before and after surgery: a pilot study. HNSCC
97  2011 Combining cytology, TRAP assay, and FISH analysis for the detection of bladder cancer in symptomatic patients. ---
98  2011 Contribution of telomere G-quadruplex stabilization to the inhibition of telomerase-mediated telomere extension by chemical ligands. ---
99  2011 Molecular analysis of T-DNA insertion mutants identified putative regulatory elements in the AtTERT gene. ---
100  2011 Prostate tumor cells with cancer progenitor properties have high telomerase activity and are rapidly killed by telomerase interference. CPCs