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Abbreviation : UDPGA
Long Form : uridine 5'-diphosphoglucuronic acid
No. Year Title Co-occurring Abbreviation
2023 Characterisation of UDP-glucuronosyltransferase activity in sea turtle Chelonia mydas. 4-MU, BSA, UGT
2022 Identification of naturally occurring inhibitors in Xian-Ling-Gu-Bao capsule against the glucuronidation of estrogens. HIM, HLM, UGT, XLGB
2021 High-resolution mass spectrometry-based approach for the identification and profiling of the metabolites of taletrectinib formed in liver microsomes. NADPH, UHPLC-HRMS
2021 Permeabilized Cryopreserved Human Hepatocytes as an Exogenous Metabolic System in a Novel Metabolism-Dependent Cytotoxicity Assay for the Evaluation of Metabolic Activation and Detoxification of Drugs Associated with Drug-Induced Liver Injuries: Results with Acetaminophen, Amiodarone, Cyclophosphamide, Ketoconazole, Nefazodone, and Troglitazone. GST, HEK293, MDCA, PAPS, SULT, UGT
2019 Identification of specific UGT1A9-mediated glucuronidation of licoricidin in human liver microsomes. HLMs, UGTs
2019 Insight into tartrate inhibition patterns in vitro and in vivo based on cocrystal structure with UDP-glucuronosyltransferase 2B15. UGTs
2019 Metabolic activation of TM5441 in vitro and in vivo: Formation of reactive metabolites and human enzymes involved. CYP450s, NAL, PAI-1, UGTs
2018 Characterization of CYPs and UGTs Involved in Human Liver Microsomal Metabolism of Osthenol. HLM, HLMs, NADPH, UGT
2018 Optimization of Experimental Conditions of Automated Glucuronidation Assays in Human Liver Microsomes Using a Cocktail Approach and Ultra-High Performance Liquid Chromatography-Tandem Mass Spectrometry. BSA, UGT
10  2017 Characterization of Phase I and Phase II Hepatic Metabolism and Reactive Intermediates of Larrea nitida Cav. and Its Lignan Compounds. MNDGA, NADPH, NDGA
11  2017 Glucuronidation of icaritin by human liver microsomes, human intestine microsomes and expressed UDP-glucuronosyltransferase enzymes: identification of UGT1A3, 1A9 and 2B7 as the main contributing enzymes. CDCA, HIM, HLM, UGT
12  2016 Optimization of a UDP-glucuronosyltransferase assay for trout liver S9 fractions: activity enhancement by alamethicin, a pore-forming peptide. BSA, UGT
13  2015 Accurate identification of UDP-glucuronosyltransferase 1A1 (UGT1A1) inhibitors using UGT1A1-overexpressing HeLa cells. UGT1A1
14  2015 Glucuronidation of bavachinin by human tissues and expressed UGT enzymes: Identification of UGT1A1 and UGT1A8 as the major contributing enzymes. BCI, BCIG, HIM, HLM, UGTs
15  2015 Significantly Different Covalent Binding of Oxidative Metabolites, Acyl Glucuronides, and S-Acyl CoA Conjugates Formed from Xenobiotic Carboxylic Acids in Human Liver Microsomes. ---
16  2014 Identification of saturated and unsaturated fatty acids released during microsomal incubations. ---
17  2014 Structure-Metabolism Relationships in the Glucuronidation of d-Amino Acid Oxidase Inhibitors. DAAO
18  2013 Glucuronidation of a sarpogrelate active metabolite is mediated by UDP-glucuronosyltransferases 1A4, 1A9, and 2B4. HLMs, UGTs
19  2012 Characterization of the metabolism of sibiricaxanthone F and its aglycone in vitro by high performance liquid chromatography coupled with Q-trap mass spectrometry. BI, EMS-IDA-EPI, MRM, SF
20  2010 Effects of acute renal failure induced by uranyl nitrate on the pharmacokinetics of liquiritigenin and its two glucuronides, M1 and M2, in rats. ARF, AUC, LQ, UGT
21  2010 Identification and characterization of oxymetazoline glucuronidation in human liver microsomes: evidence for the involvement of UGT1A9. HLMs, UGTs
22  2009 A liquid chromatography/tandem mass spectrometry method for detecting UGT-mediated bioactivation of drugs as their N-acetylcysteine adducts in human liver microsomes. ESI, NAC, UGT
23  2009 Enhanced potency of nucleotide-dendrimer conjugates as agonists of the P2Y14 receptor: multivalent effect in G protein-coupled receptor recognition. ---
24  2009 Glycerolysis of acyl glucuronides as an artifact of in vitro drug metabolism incubations. ---
25  2008 In vitro metabolism of KBH-A40, a novel delta-lactam-based histone deacetylase (HDAC) inhibitor, in human liver microsomes and serum. HDAC, NADPH
26  2008 Preparative enzymatic synthesis of glucuronides of zearalenone and five of its metabolites. UDPGT
27  2007 Characterization of 1'-hydroxymidazolam glucuronidation in human liver microsomes. UGTs
28  2007 Identification and characterization of two chloramphenicol glucuronides from the in vitro glucuronidation of chloramphenicol in human liver microsomes. CP, CPGlu, HLM, HPLC, UGT
29  2006 A simple in vitro model to study the stability of acylglucuronides. ---
30  2006 N-Glucuronidation of the antiepileptic drug retigabine: results from studies with human volunteers, heterologously expressed human UGTs, human liver, kidney, and liver microsomal membranes of Crigler-Najjar type II. UGT
31  2005 Repeated glucuronidation at one hydroxyl group leads to structurally novel diglucuronides of steroid sex hormones. ---
32  2004 Human placental glucuronidation and transport of 3'azido-3'-deoxythymidine and uridine diphosphate glucuronic acid. AZT, UGT
33  2004 Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of 3-hydroxydesloratadine. UGTs
34  2003 Structure-activity studies of glucose transfer: determination of the spontaneous rates of hydrolysis of uridine 5'-diphospho-alpha-D-glucose (UDPG) and uridine 5'-diphospho-alpha-D-glucuronic acid (UDPGA). UDPG
35  2002 Inhibition of mycophenolic acid glucuronidation by niflumic acid in human liver microsomes. MPA, NA
36  2001 Mycophenolic acid glucuronidation and its inhibition by non-steroidal anti-inflammatory drugs in human liver and kidney. MPA, NSAIDs
37  1999 Morphine regulation of a novel uridine diphosphate glucuronosyl-transferase in guinea pig pups following in utero exposure. UGTs
38  1998 Hydromorphone-3-glucuronide: biochemical synthesis and preliminary pharmacological evaluation. H3G, HPLC, HPLC-MS-MS, UV
39  1996 Glucuronidation metabolic kinetics of valproate in guinea pigs: nonlinear at clinical concentration levels. VPA
40  1995 Structure-activity relationship of a pyrimidine receptor in the rat isolated superior cervical ganglion. ATP, CTP, DPCPX, GTP, SCG, TTP, UDP, UDPG, UMP, UTP
41  1995 The use of capillary electrophoresis for studying the in vitro glucuronidation of 7-hydroxycoumarin. UDP
42  1994 Glucuronidation of N-hydroxy heterocyclic amines by human and rat liver microsomes. N-OH-ABP, N-OH-DMABP, PhIP
43  1994 Modulative effects of metabolic effectors on benzo(a)pyrene-induced cytotoxicity and mutagenicity in mammalian cells. CHO/HPRT, GSHTs, MFO
44  1992 Effect of malaria on phenol conjugation pathways in perfused rat liver. CL, MI
45  1990 Acyl glucuronidation and glucosidation of pranoprofen, a 2-arylpropionic acid derivative, in mouse liver and kidney homogenates. UDPG
46  1989 Hepatic and intestinal drug-metabolizing enzymes and the tissue distribution and excretion of 14C-7,12-dimethylbenz[a]anthracene in rats fed diets varying in fat concentration. 14C-DMBA, BPH
47  1988 Human brain metabolism of morphine and naloxone. M3G, N3G
48  1988 Localization and characterization of drug-metabolizing enzymes along the villus-crypt surface of the rat small intestine--II. Conjugases. 3-MC, GST, GT, PB
49  1987 Changes in phase I and phase II biotransformation with age in male Fischer 344 rat colon: relationship to colon carcinogenesis. ADH, BG, BPOH, GSH-Px, GST
50  1987 Effects of adenosine on glucuronidation and uridine diphosphate glucuronic acid (UDPGA) synthesis in isolated rat hepatocytes. ADO, dbcAMP
51  1987 Influence of uridine diphosphoglucuronic acid on bilirubin glucuronidation in liver microsomes from normal and spironolactone-treated rats. BDG, SP
52  1987 Product inhibition of benzo[a]pyrene metabolism in uninduced rat liver microsomes: effect of diol epoxide formation. 9-PO, BP, DE, MC, UT
53  1986 De novo pyrimidine nucleotide biosynthesis in isolated rat glomeruli. GBM, UDPAG, UDPG, UTP
54  1986 Mutagenicity of some hydroxylaminotoluene derivatives towards Salmonella typhimurium in esterification systems. 2HA4NT, 2HA6NT, 4AA2HAT, 4HA2NT, ATP, MCF, PAPS, PCP
55  1986 Nutritional parameters that alter hepatic drug metabolism, conjugation, and toxicity. MFO
56  1986 [Study of promutagen biotransformation in the Ames test. III. The role of conjugation with glucuronic acid and sulfate in the modification of mutagenic effect of nitrosomorpholine, diethylnitrosamine and cyclophosphamide]. CP, DENA, NM, PAPS
57  1984 Glucuronide conjugation reduces the cytotoxicity but not the mutagenicity of benzo(a)pyrene in the CHO/HGPRT assay. MFO
58  1983 A new assay and cellular localization for an inducible glucuronyltransferase in the embryonic chick liver. ---
59  1983 Depletion of hepatic uridine diphosphoglucuronic acid decreases the biliary excretion of drugs. DE, Gal
60  1983 Interaction of uridine 5'-diphosphoglucuronic acid (UDPGA) with cytochrome P 450. ---
61  1982 Change in kinetic properties and metabolic clearance of UDP-glucuronyltransferase for p-phenyl benzoic acid in developing fetus of rat. PPBA, UDPGT
62  1982 Determination of hepatic uridine 5'-diphosphoglucuronic acid concentration by conjugation with diethylstilbestrol. DES
63  1982 Effects of early diabetes on uridine diphosphosugar synthesis in the rat renal cortex. UDPA-GAL, UDPG, UDPgal, UTP
64  1981 Activation of phenanthrene to mutagenic metabolites and evidence for at least two different activation pathways. PAPS
65  1981 Effect of glutathione and uridine 5'-diphosphoglucuronic acid on mutagenesis by benzo[a]pyrene and aflatoxin B1 in the Salmonella/microsome assay. BP
66  1977 Modification of benzo(a)pyrene metabolism with microsomes by addition of uridine 5'-diphosphoglucuronic acid. BaP
67  1975 Recent studies on cytochrome P-450-linked functions in isolated rat liver cells. ---
68  1970 Control of colanic acid synthesis. GDPF, PFA, UDP-Gal, UDPG
69  1969 Studies on phenolic steroids in human subjects. 8. Metabolism of estriol-16 alpha-glucosiduronate. ---
70  1968 Biosynthesis of beta-glucuronides of retinol and of retinoic acid in vivo and in vitro. ---