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Abbreviation : VSMCs
Long Form : vascular smooth muscle cells
No. Year Title Co-occurring Abbreviation
2021 (-)-Epicatechin gallate blocks the development of atherosclerosis by regulating oxidative stress in vivo and in vitro. ECG, HFD, HO-1, oxLDL
2021 20-HETE-promoted cerebral blood flow autoregulation is associated with enhanced pericyte contractility. alpha-SMA, CBF, PAs
2021 5-LO-derived LTB4 plays a key role in MCP-1 expression in HMGB1-exposed VSMCs via a BLTR1 signaling axis. HMGB1, LO, LTB4, MCP-1
2021 A microRNA‑17‑5p/homeobox B13 axis participates in the phenotypic modulation of vascular smooth muscle cells. HOXB13
2021 A narrative review of exosomes in vascular calcification. VC
2021 Abnormal Pressure Stress Reduces Interleukin-1β-Induced Cyclooxygenase-2 Expression in Cultured Rat Vascular Smooth Muscle Cells. COX-2, ERK, IL, PKC, PMA
2021 Acid sphingomyelinase promotes SGK1-dependent vascular calcification. ASM, CKD, SGK1
2021 Activating BK channels ameliorates vascular smooth muscle calcification through Akt signaling. beta-GP, CKD, VC
2021 Adenine base editing to treat progeria syndrome and extend the lifespan. HGPS, LMNA
10  2021 Adipocyte factor CTRP6 inhibits homocysteine-induced proliferation, migration, and dedifferentiation of vascular smooth muscle cells through PPARγ/NLRP3. AS, Hcy
11  2021 Adipokines in vascular calcification. AT
12  2021 ALKBH1 reduces DNA N6-methyladenine to allow for vascular calcification in chronic kidney disease. 6mA, ALKBH1, CKD, suPAR
13  2021 Alternative C3 Complement System: Lipids and Atherosclerosis. AT, ECM, FH
14  2021 Ambient Particulate Matter Induces Vascular Smooth Muscle Cell Phenotypic Changes via NOX1/ROS/NF-κB Dependent and Independent Pathways: Protective Effects of Polyphenols. NADPH, PASMCs, PM, ROS
15  2021 AMPA-Type Glutamate Receptors Associated With Vascular Smooth Muscle Cell Subpopulations in Atherosclerosis and Vascular Injury. AMPA, CVD
16  2021 Analysis of crucial genes, pathways and construction of the molecular regulatory networks in vascular smooth muscle cell calcification. COs, CVSMCs, DANCR, DEGs, DETF, ECM, FOX, lncRNA, MELK, SNAI2, TFs, VC
17  2021 Angiotensin II-induced histone deacetylase 5 phosphorylation, nuclear export, and Egr-1 expression are mediated by Akt pathway in A10 vascular smooth muscle cells. Ang II, Egr-1, HDAC5, IGF-1, PI3K
18  2021 Angiotensin II-induced overexpression of sirtuin 1 contributes to enhanced expression of Giα proteins and hyperproliferation of vascular smooth muscle cells. Ang II, EGFR, IGFR, MAP, PDGFR, SIRT1
19  2021 Anisotropic Mechanics of Vascular Smooth Muscle Cells Exposed to Dynamic Loads. CBS
20  2021 Anti-Atherosclerotic Effect of Afrocyclamin A against Vascular Smooth Muscle Cells Is Mediated via p38 MAPK Signaling Pathway. ET-1, IL-1beta, MDA, NO, p-p38MAPK, PCNA, SOD, TNF-alpha, VCAM-1
21  2021 Antioxidant and Anti-atherogenic Properties of Prosopis strombulifera and Tessaria absinthioides Aqueous Extracts: Modulation of NADPH Oxidase-Derived Reactive Oxygen Species. AEPs, apoE-KO, HFD, ROS, TAS, TBARS
22  2021 Apelin receptor upregulation in spontaneously hypertensive rat contributes to the enhanced vascular smooth muscle cell proliferation by activating autophagy. 3-MA, SHR, WKY
23  2021 Apolipoprotein-AI and AIBP synergetic anti-inflammation as vascular diseases therapy: the new perspective. apoA-I, AS, CADs, ECs, PAH, VDs
24  2021 Aralia armata (Wall.) Seem Improves Intimal Hyperplasia after Vascular Injury by Downregulating the Wnt3α/Dvl-1/β-Catenin Pathway. PCR, WB
25  2021 Architecture-Dependent Mechano-Adaptation in Single Vascular Smooth Muscle Cells. CmuBS
26  2021 Association of miR-192-5p with Atherosclerosis and its Effect on Proliferation and Migration of Vascular Smooth Muscle Cells. AS
27  2021 A neutralizing IL-11 antibody reduces vessel hyperplasia in a mouse carotid artery wire injury model. CAD, IL-11, MMP-2, PAD, SM22alpha
28  2021 Berberine Reverses Nitroglycerin Tolerance through Suppressing Protein Kinase C Alpha Activity in Vascular Smooth Muscle Cells. NTG, PKC, PKCalpha
29  2021 Bioinformatics Analysis Reveals MicroRNA-193a-3p Regulates ACTG2 to Control Phenotype Switch in Human Vascular Smooth Muscle Cells. AD, miRNA
30  2021 Blocking circ_UBR4 suppressed proliferation, migration, and cell cycle progression of human vascular smooth muscle cells in atherosclerosis. AS, oxLDL, ROCK1
31  2021 Bone marrow-derived AXL tyrosine kinase promotes mitogenic crosstalk and cardiac allograft vasculopathy. CAV
32  2021 Bone mesenchymal stem cell derived exosomes alleviate high phosphorus-induced calcification of vascular smooth muscle cells through the NONHSAT 084969.2/NF-κB axis. BMSC-Exos, VC
33  2021 Calcifying characteristics of peripheral vascular smooth muscle cells of chronic kidney disease patients with critical limb ischemia. CKD, CLI, PAD
34  2021 Calcineurin (PPP3CB) regulates angiotensin II-dependent vascular remodelling by potentiating EGFR signalling in mice. Ang II, CTGF, EGFR, EMCs, HB-EGF, TGF-beta, WT
35  2021 CARMN Loss Regulates Smooth Muscle Cells and Accelerates Atherosclerosis in Mice. HCASMCs, lncRNAs, miRNAs
36  2021 CD38 deficiency alleviates Ang II-induced vascular remodeling by inhibiting small extracellular vesicle-mediated vascular smooth muscle cell senescence in mice. Ang II, NAD, SA-sEVs
37  2021 Celastrol ameliorates vascular neointimal hyperplasia through Wnt5a-involved autophagy. ---
38  2021 Cellular Crosstalk between Endothelial and Smooth Muscle Cells in Vascular Wall Remodeling. CVD, EC
39  2021 Cellular Senescence Affects Cardiac Regeneration and Repair in Ischemic Heart Disease. CM, IHD, MI, SASP, VECs
40  2021 CHOP Increases TRIB3-Dependent miR-208 Expression to Potentiate Vascular Smooth Muscle Cell Proliferation and Migration by Downregulating TIMP3 in Atherosclerosis. alpha-SMA, CHOP, miR-208, TIMP3, TRIB3
41  2021 Circadian misalignment promotes vascular smooth muscle cell apoptosis via defective autophagy. CLOCK
42  2021 CircMAPK1 promotes the proliferation and migration of vascular smooth muscle cells through miR-22-3p/ methyl-CpG binding protein 2 axis. ---
43  2021 CircMTO1 inhibits ox-LDL-stimulated vascular smooth muscle cell proliferation and migration via regulating the miR-182-5p/RASA1 axis. AS, circRNAs, oxLDL
44  2021 Circular RNA circ-ARFIP2 regulates proliferation, migration and invasion in human vascular smooth muscle cells via miR-338-3p-dependent modulation of KDR. CCK-8, circRNAs, EdU, HUASMCs, IA, KDR, miRNA, qRT-PCR, RIP, RNase
45  2021 Circular RNA circLMF1 regulates PDGF-BB-induced proliferation and migration of human aortic smooth muscle cells by regulating the miR-125a-3p/VEGFA or FGF1 axis. CCK-8, circLMF1, circRNAs, FGF1, HASMCs, miR-125a-3p, OPN, PCNA, PDGF-BB, RIP, RT-qPCR, VEGFA
46  2021 Circular RNA circUBR4 regulates ox-LDL-induced proliferation and migration of vascular smooth muscle cells through miR-185-5p/FRS2 axis. circRNAs, EdU, FRS2, oxLDL, RT-qPCR
47  2021 Circular RNA Expression: Its Potential Regulation and Function in Abdominal Aortic Aneurysms. AAAs, circRNAs, ECs
48  2021 Circular RNA PPP1CC promotes Porphyromonas gingivalis-lipopolysaccharide-induced pyroptosis of vascular smooth muscle cells by activating the HMGB1/TLR9/AIM2 pathway. circ, IL, Pg
49  2021 Circular RNA UVRAG Mediated by Alternative Splicing Factor NOVA1 Regulates Adhesion and Migration of Vascular Smooth Muscle Cells. circRNAs
50  2021 Circ_0002984 induces proliferation, migration and inflammation response of VSMCs induced by ox-LDL through miR-326-3p/VAMP3 axis in atherosclerosis. circRNAs, oxLDL, VAMP3
51  2021 Circ_0004872 promotes platelet-derived growth factor-BB-induced proliferation, migration and dedifferentiation in HA-VSMCs via miR-513a-5p/TXNIP axis. 3'UTR, alpha-SMA, AS, CCK-8, circ_0004872, HA-VSMCs, MAPK1, miR-513a-5p, mRNA, OPN, PDGF-BB, RT-qPCR, TXNIP
52  2021 Circ_GRN Promotes the Proliferation, Migration, and Inflammation of Vascular Smooth Muscle Cells in Atherosclerosis Through miR-214-3p/FOXO1 Axis. AS, circ_GRN, FOXO1, hVSMCs, miR, oxLDL
53  2021 ClC-3: A Novel Promising Therapeutic Target for Atherosclerosis. ClC-3, VRCCs
54  2021 Coenzyme Q10 inhibits intracranial aneurysm formation and progression in a mouse model. CoQ10, IA
55  2021 Crosstalk between Renal and Vascular Calcium Signaling: The Link between Nephrolithiasis and Vascular Calcification. CaSR, VECs
56  2021 Curcumin inhibits the proliferation and migration of vascular smooth muscle cells by targeting the chemerin / CMKLR1 / LCN2 axis. AS, HFD, LCN2, MMP-9, PCNA
57  2021 Curcumin nicotinate suppresses abdominal aortic aneurysm pyroptosis via lncRNA PVT1/miR-26a/KLF4 axis through regulating the PI3K/AKT signaling pathway. AAA, CUR, CurTn, KLF4, PVT1, qPCR
58  2021 Curcumin-mediated Photodynamic Therapy Inhibits the Phenotypic Transformation, Migration, and Foaming of Oxidized Low-density Lipoprotein-treated Vascular Smooth Muscle Cells by Promoting Autophagy. 3-MA, CUR, oxLDL
59  2021 Cyclin G2 promotes the formation of smooth muscle cells derived foam cells in atherosclerosis via PP2A/NF-κB/LOX-1 pathway. LOX-1, PP2A
60  2021 Decreased phosphorylation facilitates the degradation of the endogenous protective molecule c-Ski in vascular smooth muscle cells. AS, c-Ski, oxLDL, PDGF
61  2021 Deficiency of peroxisome proliferator-activated receptor α attenuates apoptosis and promotes migration of vascular smooth muscle cells. Ang, PPAR
62  2021 Degradation of Premature-miR-181b by the Translin/Trax RNase Increases Vascular Smooth Muscle Cell Stiffness. AVP
63  2021 Deletion of Fam172a accelerates advanced atherosclerosis and induces plaque instability. FAM172A
64  2021 Deletion of Superoxide Dismutase 1 Blunted Inflammatory Aortic Remodeling in Hypertensive Mice under Angiotensin II Infusion. Ang II, IL-6, PEG, SOD
65  2021 Dexamethasone reduces the formation of thoracic aortic aneurysm and dissection in a murine model. BAPN, DEX, TAAD
66  2021 Different Effects of Endothelial Extracellular Vesicles and LPS-Induced Endothelial Extracellular Vesicles on Vascular Smooth Muscle Cells: Role of Curcumin and Its Derivatives. AS, EVs, HASMCs, HUVECs, NTA, oxLDL
67  2021 Differentiation of adipose tissue-derived stem cells towards vascular smooth muscle cells on modified poly(L-lactide) foils. ADSCs, DEX, PEG, PLLA, PS
68  2021 Dihydroartemisinin ameliorates balloon injury-induced neointimal formation through suppressing autophagy in vascular smooth muscle cells. 3-MA, DHA, PDGF-BB
69  2021 Doxorubicin induces arterial stiffness: A comprehensive in vivo and ex vivo evaluation of vascular toxicity in mice. aaPWV, DOX, eNOS, NO, PE
70  2021 Effect of miR-126 on the Proliferation and Migration of Vascular Smooth Muscle Cells in Aortic Aneurysm Mice Under PI3K/AKT/mTOR Signaling Pathway. mTOR, PI3K, PTEN
71  2021 Effects of Bunao-Fuyuan decoction serum on proliferation and migration of vascular smooth muscle cells in atherosclerotic. AS, BNFY
72  2021 Effects of carotid baroreceptor stimulation on aortic remodeling in obese rats. AdipoR1, AGT, Ang II, AT1R, AT2R, CBS, ER, HFD, LEPR, NO, RAS, ROS, SBP, SNS, WAT
73  2021 Efficacy and limitations of senolysis in atherosclerosis. RS, SAbetaG, Sca-1, scRNA-seq, SIPS
74  2021 Emerging role of exosomes in arterial and renal calcification. AS, CKD, DC, EC
75  2021 Emerging Role of Pericytes and Their Secretome in the Heart. ECM
76  2021 Endolysosomal Ca2+ signaling in cardiovascular health and disease. CV, EL, NAADP, RyRs, SR/ER, TPC1-2, TRPML1
77  2021 Endothelin antagonism and sodium glucose Co-transporter 2 inhibition. A potential combination therapeutic strategy for COVID-19. ETA, SARS-CoV-2, SGLT-2
78  2021 Engineered 3D vessel-on-chip using hiPSC-derived endothelial- and vascular smooth muscle cells. ECs, hiPSCs, VoC
79  2021 Eplerenone inhibits oxidized low-density lipoprotein-induced proliferation and migration of vascular smooth muscle cells by downregulating GPER expression. AS, EPL, GPER, oxLDL
80  2021 Exosomal long non-coding RNA LIPCAR derived from oxLDL-treated THP-1 cells regulates the proliferation of human umbilical vein endothelial cells and human vascular smooth muscle cells. lncRNA, oxLDL
81  2021 Exosomal Transfer of miR-185 Is Controlled by hnRNPA2B1 and Impairs Re-endothelialization After Vascular Injury. CAD, ECs, PDGF
82  2021 Exosomes in Atherosclerosis, a Double-Edged Sword: Their Role in Disease Pathogenesis and Their Potential as Novel Therapeutics. CAD, VECs
83  2021 Extracellular signal-regulated kinase inhibition prevents venous adaptive remodeling via regulation of Eph-B4. VGA, VGS
84  2021 Extracellular vesicle-mediated miR135a-5p transfer in hypertensive rat contributes to vascular smooth muscle cell proliferation via targeting FNDC5. AFs, EVs, FNDC5, SHR, WKY
85  2021 FAK in the nucleus prevents VSMC proliferation by promoting p27 and p21 expression via Skp2 degradation. CDKIs, CDKs, FAK, Fzr1, KD, Skp2
86  2021 Fate and State of Vascular Smooth Muscle Cells in Atherosclerosis. ---
87  2021 Ferroptosis: the potential value target in atherosclerosis. AS, VECs
88  2021 Fisetin Alleviates Neointimal Hyperplasia via PPARγ/PON2 Antioxidative Pathway in SHR Rat Artery Injury Model. Ang II, PON2
89  2021 Generation of Vascular Smooth Muscle Cells From Induced Pluripotent Stem Cells: Methods, Applications, and Considerations. ---
90  2021 Globular adiponectin inhibits osteoblastic differentiation of vascular smooth muscle cells through the PI3K/AKT and Wnt/β-catenin pathway. Akt, beta-GP, CKD, gAd, VC
91  2021 Glutamine switches vascular smooth muscle cells to synthetic phenotype through inhibiting miR-143 expression and upregulating THY1 expression. MYH11, THY1
92  2021 Golgi a-mannosidase II mediates the formation of vascular smooth muscle foam cells under inflammatory stress. ER, GMII, IF, LDLR, LDLs, LPS
93  2021 H3K4 Methyltransferase Smyd3 Mediates Vascular Smooth Muscle Cell Proliferation, Migration, and Neointima Formation. PDGF
94  2021 High dose insulin promotes the proliferation of vascular smooth muscle cells via AP-1/SM-α pathway. ---
95  2021 High-mobility group box-1 promotes vascular calcification in diabetic mice via endoplasmic reticulum stress. 4-PBA, AGEs, ALP, ERS, GLY, HMGB1, ICC, IHC, RT-PCR, STZ
96  2021 Huotan Jiedu Tongluo Decoction Inhibits Balloon-Injury-Induced Carotid Artery Intimal Hyperplasia in the Rat through the PERK-eIF2α-ATF4 Pathway and Autophagy Mediation. BI, CCA, ERS, HE, HTJDTLD, HUVEC, IHC, ISR, MA, NIA, PCI, PCNA, TCM, TM
97  2021 Hydrolysis of Extracellular ATP by Vascular Smooth Muscle Cells Transdifferentiated into Chondrocytes Generates Pi but Not PPi. ADP, AMP, ATP, Pi, TNAP
98  2021 Identification of Differently Expressed mRNAs in Atherosclerosis Reveals CDK6 Is Regulated by circHIPK3/miR-637 Axis and Promotes Cell Growth in Human Vascular Smooth Muscle Cells. CircRNA, DEGs, PPI
99  2021 Identification of transfer RNA-derived fragments and their potential roles in aortic dissection. AD, tRFs, tRNA
100  2021 IKKε knockout alleviates angiotensin II-induced apoptosis and excessive autophagy in vascular smooth muscle cells by regulating the ERK1/2 pathway. AAA, Ang II, IKKepsilon