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Abbreviation : WKY
Long Form : Wistar-Kyoto normotensive rats
No. Year Title Co-occurring Abbreviation
2021 Anti-apoptotic and pro-survival effect of exercise training on early aged hypertensive rat cerebral cortex. AIF, EndoG, IGF, TNF
2021 Tengdan Capsule Prevents Hypertensive Kidney Damage in SHR by Inhibiting Periostin-Mediated Renal Fibrosis. BP, BUN, CRE, HPLC, SHR, TDC
2021 Time-Dependent Effects of Individual and Combined Treatments With Nebivolol, Lisinopril, and Valsartan on Blood Pressure and Vascular Reactivity to Angiotensin II and Norepinephrine. SHR
2013 A single exposure to acrolein desensitizes baroreflex responsiveness and increases cardiac arrhythmias in normotensive and hypertensive rats. ECG, HR, SH
2013 Role of (pro)rennin receptor in cardiomyocytes of heart failure rat model. HF, IVS, LV, sh-RNA, SHR
2012 Dobutamine "stress" test and latent cardiac susceptibility to inhaled diesel exhaust in normal and hypertensive rats. DE, ECG, HR, SH
2010 Regulation of 3',5'-cAMP in preglomerular smooth muscle and endothelial cells from genetically hypertensive rats. PDE4, SHR
2010 Wistar-Kyoto and spontaneously hypertensive rat blood pressure after embryo transfer into different wombs and cross-suckling. BP, BW
2008 Changes in mitochondrial functionality and calcium uptake in hypertensive rats as a function of age. SHR
10  2008 Surges of arterial pressure during REM sleep in spontaneously hypertensive rats. REM sleep, SHR
11  2007 Central and baroreflex control of heart period during the wake-sleep cycle in spontaneously hypertensive rats. CCF, NREMS, QW, REMS, SHR
12  2003 Peripheral tissue distribution of orphanin FQ precusor mRNA in stroke-prone spontaneously hypertensive rats. OFQ, RT-PCR, SHRSP, VSMCs
13  2003 Responsiveness, affinity constants and beta 2-adrenoceptor reserves for isoprenaline on portal veins from normo- and pre- and hypertensive rats. BAAM, SHRs
14  2002 Responsiveness, affinity constants and beta-adrenoceptor reserves for isoprenaline on aortae from normo-, pre- and hypertensive rats. BAAM, SHRs
15  2001 Effects of clofilium on cardiovascular tissues from normo- and hypertensive rats. SHRs
16  2001 Effects of tedisamil on cardiovascular tissues isolated from normo- and hypertensive rats. ---
17  2001 Hypertension in normotensive and hypertensive rats by spermine ingestion. ANP, EIA, SHR
18  2001 Increased response to prostaglandin H2 precedes changes in PGH synthase-1 expression in the SHR aorta. RT-PCR
19  2001 Potency, affinity constants and receptor reserves for noradrenaline and adrenaline on aortae from aged normo- and hypertensive rats. SHRs
20  2001 Responsiveness, affinity constants and receptor reserves for serotonin on aortae of aged normotensive and hypertensive rats. SHRs
21  2000 Multiple evidence of a segmental defect in the anterior forebrain of an animal model of hyperactivity and attention deficit. CaMKII, DA, ICC, MPH, SHR, TFs
22  2000 Remodeling of neural networks in the anterior forebrain of an animal model of hyperactivity and attention deficits as monitored by molecular imaging probes. ADHD, CaMKII, CO, DA, MP, SHR, TF
23  2000 Sodium intake is increased by social stress and the Y chromosome and reduced by clonidine. SHR, SNS, Yc
24  1999 Effects of BDF 9148 on the action potentials and contractions of left ventricles from normo- and hypertensive rats. SHR
25  1999 Effects of tetraethylammonium, 4-aminopyridine and bretylium on cardiovascular tissues from normo- and hypertensive rats. SHRs
26  1998 Regional sympathetic activity in pre-hypertensive phase of spontaneously hypertensive rats. NE, SHR, SNS
27  1998 The relaxing effect of BDF 9148 on the KCl-contracted aorta isolated from normo- and hyper-tensive rats. SHRs
28  1996 Extracellular catechol and indole turnover in the nucleus of the solitary tract of spontaneously hypertensive and Wistar-Kyoto normotensive rats in response to drug-induced changes in arterial blood pressure. 5-HIAA, NE, NTS, SHRs
29  1996 Physiological Role of Brain Angiotensin III in Drinking Behavior in the Rat. AIII, i.c.v, SH
30  1996 Plasma membrane calcium pump-mediated calcium efflux and bulk cytosolic free calcium in cultured aortic smooth muscle cells from spontaneously hypertensive and Wistar-Kyoto normotensives rats. SHR
31  1996 Vascular effects of metformin. Possible mechanisms for its antihypertensive action in the spontaneously hypertensive rat. SHR, SM
32  1995 Insight into blood-pressure control in SHR via the response to acute hemorrhage: a spectral analysis approach. ABP, SHR
33  1994 Different effects of amphetamine on reinforced variations versus repetitions in spontaneously hypertensive rats (SHR). ADHD, SHR
34  1994 Enhanced 45Ca2+ efflux in cultured vascular smooth muscle cells from spontaneously hypertensive rats. SHR, VSMC
35  1994 Monocyte adhesion to cerebromicrovascular endothelial cells derived from hypertensive and normotensive rats. EC, ICAM-1, SHR
36  1993 Dissociation of catecholamine and corticosterone responses to different types of stress in rats. SHR
37  1993 High sensitivity of hypertensive aortic myocytes to norepinephrine and angiotensin. SHR
38  1993 Potassium channel antagonists and vascular reactivity in stroke-prone spontaneously hypertensive rats. SHRSP
39  1993 Spontaneously hypertensive rats (SHR) readily learn to vary but not repeat instrumental responses. ADDH, SHR
40  1992 Extracellular calcium, contractile activity and membrane potential in tail arteries from genetically hypertensive rats. SHRSP
41  1992 Nonendothelial aortic source of nitric oxide in Wistar-Kyoto normotensive and spontaneous hypertensive rats. L-Arg, L-NAME, NO, SHR
42  1991 Down-regulation of brain and spinal cord K-opiate receptors in spontaneously hypertensive, Wistar-Kyoto normotensive, and Sprague-Dawley rats by chronic treatment with U-50, 488H. SD, SHR
43  1991 Effect of hydralazine on the mesenteric vasculature of hypertensive rats. SHR
44  1990 Aminopeptidase-induced elevations and reductions in blood pressure in the spontaneously hypertensive rat. APA, LAP-M, SHR
45  1990 Augmented phosphoinositide metabolism in aortas from genetically hypertensive rats. NCDC, SHRSP
46  1990 Changes of beta-adrenoceptors in the aortic muscle cells of spontaneously hypertensive rats. SHR
47  1990 Enhanced vasomotion of cerebral arterioles in spontaneously hypertensive rats. SHR
48  1990 Intracellular Ca2+ metabolism of isolated resistance arteries and cultured vascular myocytes of spontaneously hypertensive and Wistar-Kyoto normotensive rats. SHR
49  1990 Resistance artery phosphoinositide metabolism in genetic hypertension. SHR
50  1990 [Genetic abnormalities in cultured cutaneous fibroblasts in SHR rats]. SHR
51  1989 Defective modulation of noradrenergic neurotransmission by endogenous prostaglandins in aging spontaneously hypertensive rats. Ang II, NE, PNS, SHR
52  1989 Defective modulation of noradrenergic neurotransmission by exogenous prostaglandins in aging spontaneously hypertensive rats. SHR
53  1989 Enhanced release of atrial natriuretic factor by endothelin in atria from hypertensive rats. ANF, IR-ANF, SHR
54  1989 Erythrocyte membrane calcium adenosine 5'-triphosphatase activity in the spontaneously hypertensive rat. ATP, IOVs, SHR
55  1989 Strain, age, but not gender, influence ulcer severity induced by water-restraint stress. BT, LE, SD, SHR, SR, WR
56  1988 Auditory startle in normotensive and hypertensive rats. BHR, SHR
57  1988 Endothelial regulation of cyclic GMP and vascular responses in hypertension. ACh, DOCA, NE, SHR
58  1988 Structural and reactivity alterations of the renal vasculature of spontaneously hypertensive rats prior to and during established hypertension. RVR, SHR, SMCs
59  1987 Effects of an angiotensin-converting enzyme (ACE) inhibitor, SA446, on tissue ACE activity in normotensive, spontaneously hypertensive, and renal hypertensive rats. ACE, RHR, SHR
60  1987 Elastin and elastase-like enzyme change in aorta of rat with malignant hypertension. SHRSP
61  1987 High resolution 23Na-nuclear magnetic resonance study of stroke-prone spontaneously hypertensive rat erythrocytes. NMR, SHRSP, TTHA
62  1987 Increased 45Ca influx in response to alpha 1-adrenoceptor stimulation in spontaneously hypertensive rat caudal artery. NE, SHR
63  1987 Preweanling behavioral development in spontaneously hypertensive, borderline hypertensive, and Wistar-Kyoto normotensive rats. BHR, SHR
64  1987 Scanning electron microscopy of vascular smooth muscle cells from rat muscular arteries. SEM, SHR, SMC
65  1986 Age dependent changes in myosin ATPase activity in the myocardium of spontaneously hypertensive rats. SHR
66  1985 A Na+-Ca2+ exchange process in isolated sarcolemmal membranes of mesenteric arteries from WKY and SHR rats. SHR
67  1985 Effect of swimming training on cardiac function and myosin ATPase activity in SHR. ATPase, SHR
68  1985 Effects of ethanol on reproduction and arterial hypertension in spontaneously hypertensive and normotensive rats: a preliminary communication. SHR
69  1985 Structural and functional adaptation in the rat myocardium and coronary vascular bed caused by changes in pressure and volume load. LV, SHR
70  1984 Contractile responses of vasa deferentia from rats with genetic and experimental hypertension. DHR, DOC, NE, NWR, SHR
71  1984 On the abnormalities of contractile responses of rat vasa deferentia to norepinephrine in genetic hypertension. DHR, DNR, DOC, NE, SHR
72  1984 Release of prostaglandins by the mesenteric artery of the renovascular and spontaneously hypertensive rat. 6-keto-PGF1 alpha, NE, PGE2, SHR
73  1983 Dissociation of genetic hyperactivity and hypertension in SHR. BP, SHR
74  1983 Effect of the intracerebroventricular injection of dopamine on blood pressure in the spontaneously hypertensive rat. DOC, i.c.v, SHR
75  1983 Sympathetic nerves and adrenal medulla: contributions to cardiovascular-conditioned emotional responses in spontaneously hypertensive rats. HR, MAP, SHR
76  1983 Ultrastructural changes in mesenteric arteries from spontaneously hypertensive rats. A morphometric study. IEL, SHR, SMC
77  1983 Vasodilator responses to cholinergic and adrenergic stimulants in spontaneously hypertensive (SHR) and Wistar-Kyoto (WKY) normotensive rats. MAP, SHR
78  1982 Altered renal alpha 2-adrenergic receptor regulation in genetically hypertensive rats. SHR
79  1982 Effect of clonidine and propranolol on venous smooth muscle from spontaneously hypertensive rats. GAG's, PA
80  1982 Erythrocytic sodium ion transport systems in primary and secondary hypertension of the rat. SHR
81  1982 Left ventricular hypertrophy improves cardiac performance in spontaneously hypertensive rats. LVEDP, SHR, SV
82  1982 Red blood cell and plasma distribution in SHR cremaster muscle microvessels. DTAF-RBC, FITC, SHR
83  1982 Sympathetic supraspinal control of venous membrane potential in spontaneous hypertension in vivo. PBZ, SHR
84  1981 Differential effects of D 600 on contractile response of aorta and portal vein from spontaneously hypertensive rats. SHR
85  1981 Norepinephrine effect on in situ venous membrane potential in spontaneously hypertensive rats. NE, PSS, SHR, TTX, VSM
86  1981 Whole-body venous capacity and effective total tissue compliance in SHR. ETTC, MCFP, SHR
87  1980 Possible role of phosphorylation-dephosphorylation in the regulation of calcium metabolism in cardiovascular tissues of SHR. SHR
88  1979 Evidence for enhanced sodium transport in the tail artery of the spontaneously hypertensive rat. PSS, SHR
89  1979 Natural biventricular hypertrophy in normotensive rats. I. Physical and hemodynamic characteristics. BVH, SHR
90  1979 Serial renin-angiotensin studies in spontaneously hypertensive and Wistar-Kyoto normotensive rats. Transition from normal- to high-renin status during the established phase of spontaneous hypertension. PRA, PRC, SHR
91  1978 Fluid volumes during onset of spontaneous hypertension in rats. ECFV, MAP, NR, PV, SHR, TBWV
92  1978 Renal prostaglandin production in the Japanese (Kyoto) spontaneously hypertensive rat. PGE2, PGF2 alpha, SH
93  1978 Vasoconstrictor hyperresponsiveness: an early pathogenic mechanism in the spontaneously hypertensive rat. NE, SHR