| 1 |
2022 |
Combination of Clptm1L and TMEM207 Expression as a Robust Prognostic Marker in Oral Squamous Cell Carcinoma. |
Clptm1L, ER, OSCC |
| 2 |
2022 |
EHBP1, TUBB, and WWOX SNPs, Gene-Gene and Gene-Environment Interactions on Coronary Artery Disease and Ischemic Stroke. |
CAD, EHBP1, IS, SNPs, TUBB |
| 3 |
2022 |
Novel Mutation With Literature Review WW Domain-Containing Oxidoreductase (WWOX) Gene. |
WES |
| 4 |
2022 |
Structural insights into the role of the WW2 domain on tandem WW/PPxY-motif interactions of oxidoreductase WWOX. |
ITC, NMR |
| 5 |
2021 |
Altered neocortical oscillations and cellular excitability in an in vitro Wwox knockout mouse model of epileptic encephalopathy. |
--- |
| 6 |
2021 |
Angiomotin Counteracts the Negative Regulatory Effect of Host WWOX on Viral PPxY-Mediated Egress. |
AMOT, LASV, VLPs |
| 7 |
2021 |
Associations between TUBB-WWOX SNPs, their haplotypes, gene-gene, and gene-environment interactions and dyslipidemia. |
SNPs, TUBB |
| 8 |
2021 |
Cellular Expression and Subcellular Localization of Wwox Protein During Testicular Development and Spermatogenesis in Rats. |
--- |
| 9 |
2021 |
Downregulated Expression of WWOX in Cervical Carcinoma: A Case-Control Study. |
HPV |
| 10 |
2021 |
Effect of WW Domain-Containing Oxidoreductase Gene Polymorphism on Clinicopathological Characteristics of Patients with EGFR Mutant Lung Adenocarcinoma in Taiwan. |
EGFR, OR |
| 11 |
2021 |
Expression of WW domain-containing oxidoreductase and its clinical implication in endometrial adenocarcinoma patients with metabolic syndrome. |
MS, OS |
| 12 |
2021 |
Genetic Neonatal-Onset Epilepsies and Developmental/Epileptic Encephalopathies with Movement Disorders: A Systematic Review. |
DE/EE, MD |
| 13 |
2021 |
Genome-wide association and transcriptome analysis suggests total serum ghrelin to be linked with GFRAL. |
CNTNAP2, GDF15, GFRAL, GHRL, GWAS, RPL36, TWAS |
| 14 |
2021 |
Identification of a novel association for the WWOX/HIF1A axis with gestational diabetes mellitus (GDM). |
GDM, HIF1 |
| 15 |
2021 |
In vitro and in silico assessment of the effect of WWOX expression on invasiveness pathways associated with AP-2 transcription factors in bladder cancer. |
AP-2 |
| 16 |
2021 |
Methylation of WWOX gene promotes proliferation of osteosarcoma cells. |
CCK-8 |
| 17 |
2021 |
Modeling genetic epileptic encephalopathies using brain organoids. |
DEE, SCAR12, WOREE |
| 18 |
2021 |
Molecular Functions of WWOX Potentially Involved in Cancer Development. |
--- |
| 19 |
2021 |
Neonatal neuronal WWOX gene therapy rescues Wwox null phenotypes. |
SCAR12, WOREE |
| 20 |
2021 |
Neurological Disorders Associated with WWOX Germline Mutations-A Comprehensive Overview. |
SCAR12 |
| 21 |
2021 |
Photoreceptor Cell Calcium Dysregulation and Calpain Activation Promote Pathogenic Photoreceptor Oxidative Stress and Inflammation in Prodromal Diabetic Retinopathy. |
CI |
| 22 |
2021 |
RHBDD2‑WWOX protein interaction during proliferative and differentiated stages in normal and breast cancer cells. |
RHBDD2 |
| 23 |
2021 |
Synergistic effect of toosendanin and regorafenib against cell proliferation and migration by regulating WWOX signaling pathway in hepatocellular carcinoma. |
HCC, RGF, TRC, TSN |
| 24 |
2021 |
WWOX activation by toosendanin suppresses hepatocellular carcinoma metastasis through JAK2/Stat3 and Wnt/beta-catenin signaling. |
HCC, TSN |
| 25 |
2021 |
WWOX and Its Binding Proteins in Neurodegeneration. |
AD |
| 26 |
2021 |
WWOX-Related Neurodevelopmental Disorders: Models and Future Perspectives. |
DEEs |
| 27 |
2020 |
A Chinese patient with epilepsy and WWOX compound heterozygous mutations. |
--- |
| 28 |
2020 |
Aberrant expression of WWOX and its association with cancer stem cell biomarker expression. |
CSCs, IBC, LNM, OS, TNM |
| 29 |
2020 |
Characterization of WWOX expression and function in canine mast cell tumors and malignant mast cell lines. |
MCTs |
| 30 |
2020 |
Clinical epigenetics and multidrug-resistant bacterial infections: host remodelling in critical illness. |
HDACi, MDR, MLH1 |
| 31 |
2020 |
Early onset epileptic encephalopathy caused by novel compound heterozygous mutation of WWOX gene. |
WOREE |
| 32 |
2020 |
Expression and clinical significance of WWOX, Elf5, Snail1 and EMT related factors in epithelial ovarian cancer. |
EMT |
| 33 |
2020 |
Pleiotropic tumor suppressor functions of WWOX antagonize metastasis. |
EMT, miRNAs, TNBC |
| 34 |
2020 |
The correlation of the expressions of WWOX, LGR5 and vasohibin-1 in epithelial ovarian cancer and their clinical significance. |
CSCs, EOC, FIGO, LGR5, LNM, OS, VASH1 |
| 35 |
2020 |
Virus-encoded miR-155 ortholog in Marek's disease virus promotes cell proliferation via suppressing apoptosis by targeting tumor suppressor WWOX. |
CEF, KSHV, MD, MDV-1, miR-155, miRNAs |
| 36 |
2020 |
Wwox Deficiency Causes Downregulation of Prosurvival ERK Signaling and Abnormal Homeostatic Responses in Mouse Skin. |
--- |
| 37 |
2020 |
WWOX promotes apoptosis and inhibits autophagy in paclitaxel‑treated ovarian carcinoma cells. |
EOC, PARP, PTX |
| 38 |
2020 |
WWOX regulates the Elf5/Snail1 pathway to affect epithelial-mesenchymal transition of ovarian carcinoma cells in vitro. |
EMT |
| 39 |
2019 |
A 16q22.2-q23.1 deletion identified in a male infant with West syndrome. |
ID, VPA |
| 40 |
2019 |
Decoding the link between WWOX and p53 in aggressive breast cancer. |
BLBC, TNBC |
| 41 |
2019 |
Delineating WWOX Protein Interactome by Tandem Affinity Purification-Mass Spectrometry: Identification of Top Interactors and Key Metabolic Pathways Involved. |
ER, TAP-MS, TCA |
| 42 |
2019 |
Functional genetic variant of WW domain containing oxidoreductase gene associated with urothelial cell carcinoma clinicopathologic characteristics and long-term survival. |
DSS, UCC |
| 43 |
2019 |
Loss of Wwox Causes Defective Development of Cerebral Cortex with Hypomyelination in a Rat Model of Lethal Dwarfism with Epilepsy. |
--- |
| 44 |
2019 |
Novel compound heterozygous mutations in the WWOX gene cause early infantile epileptic encephalopathy. |
SCAR12 |
| 45 |
2019 |
Novel WWOX deleterious variants cause early infantile epileptic encephalopathy, severe developmental delay and dysmorphism among Yemenite Jews. |
--- |
| 46 |
2019 |
Quest for Tangible Biomarkers for Triple-Negative Breast Cancer. |
TNBC |
| 47 |
2019 |
The clinicopathological significance of ubiquitin-conjugating enzyme E2C, leucine-rich repeated-containing G protein-coupled receptor, WW domain-containing oxidoreductase, and vasculogenic mimicry in invasive breast carcinoma. |
DFS, IBC, LNM, MVD, OS, TNM, UBE2C, VM |
| 48 |
2019 |
Wwox Deletion in Mouse B Cells Leads to Genomic Instability, Neoplastic Transformation, and Monoclonal Gammopathies. |
CSR, DSB |
| 49 |
2018 |
A novel missense variant in the SDR domain of the WWOX gene leads to complete loss of WWOX protein with early-onset epileptic encephalopathy and severe developmental delay. |
SDR |
| 50 |
2018 |
Association of WWOX rs9926344 polymorphism with poor prognosis of hepatocellular carcinoma. |
HCC, SNPs, TOFMS |
| 51 |
2018 |
Cancerous Protein Network That Inhibits the Tumor Suppressor Function of WW Domain-Containing Oxidoreductase (WWOX) by Aberrantly Expressed Molecules. |
--- |
| 52 |
2018 |
Correlation of expression of WWOX and JNK with clinicopathologic features in human breast carcinoma. |
IHC, JNK, RT-PCR |
| 53 |
2018 |
Expression of B Cell-Specific Moloney Murine Leukemia Virus Integration Site 1 (BMI-1) and WW Domain-Containing Oxidoreductase (WWOX) in Liver Cancer Tissue and Normal Liver Tissue. |
ANOVA, Bmi-1, RT-PCR |
| 54 |
2018 |
Immunohistochemical WWOX Expression and Association with Angiogenesis, p53 Expression, Cell Proliferation and Clinicopathological Parameters in Cervical Cancer. |
ICSCC |
| 55 |
2018 |
LncRNA WWOX‑AS1 inhibits the proliferation, migration and invasion of osteosarcoma cells. |
lnc |
| 56 |
2018 |
Loss of Wwox drives metastasis in triple-negative breast cancer by JAK2/STAT3 axis. |
BC, TNBC |
| 57 |
2018 |
Low expression of WW domain-containing oxidoreductase associates with hepatocellular carcinoma aggressiveness and recurrence after curative resection. |
AFP, DCA, gamma-GT, HCC, OS, RFS |
| 58 |
2018 |
Modeling WWOX Loss of Function in vivo: What Have We Learned? |
CFS, SDR |
| 59 |
2018 |
Relationship of genetic variant distributions of WW domain-containing oxidoreductase gene with uterine cervical cancer. |
SNPs |
| 60 |
2018 |
Somatic loss of WWOX is associated with TP53 perturbation in basal-like breast cancer. |
BLBC, TNBC |
| 61 |
2018 |
The downregulation of WWOX induces epithelial-mesenchymal transition and enhances stemness and chemoresistance in breast cancer. |
--- |
| 62 |
2018 |
VOPP1 promotes breast tumorigenesis by interacting with the tumor suppressor WWOX. |
VOPP1 |
| 63 |
2018 |
WWOX controls hepatic HIF1α to suppress hepatocyte proliferation and neoplasia. |
HCC, HIF-1alpha |
| 64 |
2018 |
WWOX-associated encephalopathies: identification of the phenotypic spectrum and the resulting genotype-phenotype correlation. |
SCAR12 |
| 65 |
2017 |
A new tumor suppressor lncRNA RP11-190D6.2 inhibits the proliferation, migration, and invasion of epithelial ovarian cancer cells. |
EOC, lncRNAs |
| 66 |
2017 |
Decreased WWOX expression promotes angiogenesis in osteosarcoma. |
MVD |
| 67 |
2017 |
Evodiamine Exerts an Anti-Hepatocellular Carcinoma Activity through a WWOX-Dependent Pathway. |
HCC |
| 68 |
2017 |
Exogenous WWOX enhances apoptosis and weakens metastasis in CNE2 nasopharyngeal carcinoma cells through the intrinsic apoptotic pathway. |
NPC |
| 69 |
2017 |
Exosomes containing differential expression of microRNA and mRNA in osteosarcoma that can predict response to chemotherapy. |
CDC5L, CIP4, mRNAs, MTAP, OS, PEDF |
| 70 |
2017 |
Exploring the mechanism of WWOX growth inhibitory effects on oral squamous cell carcinoma. |
ERK/MAPK, OSCC |
| 71 |
2017 |
Expression of ORAOV1, CD133 and WWOX correlate with metastasis and prognosis in gastric adenocarcinoma. |
GAC, LNM, ORAOV1, TNM |
| 72 |
2017 |
Functional genetic variant of WW domain-containing oxidoreductase (WWOX) gene is associated with hepatocellular carcinoma risk. |
ALT, HCC, SNP, SNPs |
| 73 |
2017 |
Functions and Epigenetic Regulation of Wwox in Bone Metastasis from Breast Carcinoma: Comparison with Primary Tumors. |
HGF, TAZ |
| 74 |
2017 |
Loss of lung WWOX expression causes neutrophilic inflammation. |
--- |
| 75 |
2017 |
PARTICLE triplexes cluster in the tumor suppressor WWOX and may extend throughout the human genome. |
--- |
| 76 |
2017 |
Recurrent alterations of the WW domain containing oxidoreductase gene spanning the common fragile site FRA16D in multiple myeloma and monoclonal gammopathy of undetermined significance. |
CFS, MGUS, MM |
| 77 |
2017 |
The circRNA interactome-innovative hallmarks of the intra- and extracellular radiation response. |
circRNAs, IR, ncRNA, QKI |
| 78 |
2017 |
The long non-coding RNA PARTICLE is associated with WWOX and the absence of FRA16D breakage in osteosarcoma patients. |
--- |
| 79 |
2017 |
The non-inflammatory role of C1q during Her2/neu-driven mammary carcinogenesis. |
--- |
| 80 |
2017 |
TMEM207 hinders the tumour suppressor function of WWOX in oral squamous cell carcinoma. |
OSCC |
| 81 |
2017 |
WW domain-binding protein 2: an adaptor protein closely linked to the development of breast cancer. |
ER, PAX8, PR, WBP2, Yap |
| 82 |
2017 |
WWOX sensitises ovarian cancer cells to paclitaxel via modulation of the ER stress response. |
EOC, ER, GRP78, OS, PFS |
| 83 |
2016 |
Association of polymorphisms in WWOX gene with risk and outcome of osteosarcoma in a sample of the young Chinese population. |
SNPs |
| 84 |
2016 |
Deregulated WWOX is involved in a negative feedback loop with microRNA-214-3p in osteosarcoma. |
EMT, miR |
| 85 |
2016 |
Ectopic WWOX Expression Inhibits Growth of 5637 Bladder Cancer Cell In Vitro and In Vivo. |
--- |
| 86 |
2016 |
Functional genetic variant in the Kozak sequence of WW domain-containing oxidoreductase (WWOX) gene is associated with oral cancer risk. |
--- |
| 87 |
2016 |
Genetic association study identifies a functional CNV in the WWOX gene contributes to the risk of intracranial aneurysms. |
IAs |
| 88 |
2016 |
Reduced expression of the WW domain-containing oxidoreductase in human hematopoietic malignancies. |
--- |
| 89 |
2016 |
Role of WW Domain-containing Oxidoreductase WWOX in Driving T Cell Acute Lymphoblastic Leukemia Maturation. |
--- |
| 90 |
2016 |
The influence of the WWOX gene on the regulation of biological processes during endometrial carcinogenesis. |
CDH1, CTNNB1, EZR, MMP-2, PTEN, VIM, ZEB1 |
| 91 |
2016 |
The role of WWOX polymorphisms on COPD susceptibility and pulmonary function traits in Chinese: a case-control study and family-based analysis. |
SNPs |
| 92 |
2016 |
W44X mutation in the WWOX gene causes intractable seizures and developmental delay: a case report. |
WES |
| 93 |
2016 |
WWOX CNV-67048 Functions as a Risk Factor for Epithelial Ovarian Cancer in Chinese Women by Negatively Interacting with Oral Contraceptive Use. |
CNVs, EOC |
| 94 |
2016 |
WWOX inhibits the invasion of lung cancer cells by downregulating RUNX2. |
MMP-9 |
| 95 |
2015 |
Adenovirus-delivered wwox inhibited lung cancer growth in vivo in a mouse model. |
AFP, CEA, PCNA |
| 96 |
2015 |
Allostery mediates ligand binding to WWOX tumor suppressor via a conformational switch. |
PPxY |
| 97 |
2015 |
Ectopic expression of the WWOX gene suppresses stemness of human ovarian cancer stem cells. |
NOD, SCID |
| 98 |
2015 |
Effect of the WWOX gene on the regulation of the cell cycle and apoptosis in human ovarian cancer stem cells. |
CDK, JNK, PCR |
| 99 |
2015 |
Identification of a possible susceptibility locus for UVB-induced skin tanning phenotype in Korean females using genomewide association study. |
GWA, SNPs, UV |
| 100 |
2015 |
Loss of wwox expression in zebrafish embryos causes edema and alters Ca(2+) dynamics. |
--- |
A Search Service for Abbreviation / Long Form
