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Abbreviation : XOD
Long Form : xanthine oxidase
No. Year Title Co-occurring Abbreviation
2022 In vitro and in vivo ameliorative effects of polyphenols from purple potato leaves on renal injury and associated inflammation induced by hyperuricemia. PSPLP
2022 [Effects of medium and long-term insulin pretreatment on the activity of main oxidase and antioxidant enzyme in the myocardium of burned rats with delayed fluid resuscitation]. CAT, Cu,Zn-SOD, GSH-Px, MPO, NPH, SD, TBSA
2021 Anti-Hyperuricemic and Nephroprotective Effects of Dihydroberberine in Potassium Oxonate- and Hypoxanthine-Induced Hyperuricemic Mice. ADA, ASC, BBR, BUN, DHB, NLRP3
2021 Antihyperuricemia and antigouty arthritis effects of Persicaria capitata herba in mice. GLUT9, HUA, MSUC, URAT1
2021 Antihyperuricemic Effect of Dendropanax morbifera Leaf Extract in Rodent Models. ALP, ALT, DMLE, PO, UA
2021 Astaxanthin attenuated hyperuricemia and kidney inflammation by inhibiting uric acid synthesis and the NF-kappa B/NLRP3 signaling pathways in potassium oxonate and hypoxanthine-induced hyperuricemia mice. ADA, ASX, BUN, Cr, HX, PO, UA
2021 Chlorogenic acid supplementation ameliorates hyperuricemia, relieves renal inflammation, and modulates intestinal homeostasis. BUN, CGA, Cr, HUA, IL, LPS, NLRP3, SCFAs, TNF, UA, ZO-1
2021 Design, synthesis and bioactive evaluation of geniposide derivatives for antihyperuricemic and nephroprotective effects. ---
2021 Determination of inhibitory activity of Salvia miltiorrhiza extracts on xanthine oxidase with a paper-based analytical device. PAD, SME
10  2021 Effects of Macroporous Resin Extract of Dendrobium officinale Leaves in Rats with Hyperuricemia Induced by Fructose and Potassium Oxonate. ABCG2, Cr, DoMRE, GLUT9, SUA, UA, URAT1
11  2021 Elevated Serum Uric Acid is Associated With Poor Survival in Advanced HCC Patients and Febuxostat Improves Prognosis in HCC Rats. DEN, HCC
12  2021 Ellagic Acid Exerts Beneficial Effects on Hyperuricemia by Inhibiting Xanthine Oxidase and NLRP3 Inflammasome Activation. EA, MSU, UA
13  2021 Enhancement of oral bioavailability and anti-hyperuricemic activity of aloe emodin via novel Soluplus-glycyrrhizic acid mixed micelle system. AE, AE-M, IL, MSU
14  2021 Evaluation of Enzyme Inhibitory Activity of Flavonoids by Polydopamine-Modified Hollow Fiber-Immobilized Xanthine Oxidase. PDA
15  2021 Exploring the potential of novel xanthine oxidase inhibitory peptide (ACECD) derived from Skipjack tuna hydrolysates using affinity-ultrafiltration coupled with HPLC-MALDI-TOF/TOF-MS. ACECD, HS, MW, XODI
16  2021 Expression and role of interleukin-1beta and associated biomarkers in deep vein thrombosis. CECs, DVT, IL-1beta, TF
17  2021 Flower beverages of native medicinal plants from Argentina (Acacia caven, Geoffroea decorticans and Larrea divaricata) as antioxidant and anti-inflammatory. LOX
18  2021 Impact of Camellia japonica Bee Pollen Polyphenols on Hyperuricemia and Gut Microbiota in Potassium Oxonate-Induced Mice. ABCG2, CPE-E, GLUT9, NLRP3, OAT1, OCT1, PO, URAT1
19  2021 Inflammatory Response and Oxidative Stress as Mechanism of Reducing Hyperuricemia of Gardenia jasminoides-Poria cocos with Network Pharmacology. GPE, HUA
20  2021 Inhibitory mechanism of xanthine oxidase activity by caffeoylquinic acids in vitro. CQAs, diCQAs, monoCQAs
21  2021 Isorhamnetin, the xanthine oxidase inhibitor from Sophora japonica, ameliorates uric acid levels and renal function in hyperuricemic mice. IRh, PO, UA, WSF
22  2021 Lactic acid bacteria strains relieve hyperuricaemia by suppressing xanthine oxidase activity via a short-chain fatty acid-dependent mechanism. LAB, LPS, SCFA, UA
23  2021 Natural Xanthine Oxidase Inhibitor 5-O-Caffeoylshikimic Acid Ameliorates Kidney Injury Caused by Hyperuricemia in Mice. SGR
24  2021 New Lignanamides with Antioxidant and Anti-Inflammatory Activities Screened Out and Identified from Warburgia ugandensis Combining Affinity Ultrafiltration LC-MS with SOD and XOD Enzymes. ABTS, COX-2, DPPH, FRAP, SOD
25  2021 Orange emissive carbon dots for fluorescent determination of hypoxanthine in fish. HX, NTBC, O-CDs
26  2021 Pharmacological Basis for Use of a Novel Compound in Hyperuricemia: Anti-Hyperuricemic and Anti-Inflammatory Effects. GLUT9, HE, URAT1
27  2021 Pyroptosis inhibition alleviates potassium oxonate- and monosodium urate-induced gouty arthritis in mice. BUN, MSU, PO, qRT-PCR
28  2021 Pyroptosis inhibition alleviates potassium oxonate- and monosodium urate-induced gouty arthritis in mice. BUN, MSU, PO, qRT-PCR
29  2021 Screening of Xanthine Oxidase Inhibitors by Liquid Crystal-Based Assay Assisted with Enzyme Catalysis-Induced Aptamer Release. LC
30  2021 Sensitive ratiometric fluorescence assay for detecting xanthine in serum based on the inner filter effect of enzyme-catalyzed oxidation products to silicon nanoparticles. DAP, HRP, IFE, SiNPs
31  2021 Sonneratia apetala seed oil attenuates potassium oxonate/hypoxanthine-induced hyperuricemia and renal injury in mice. CRE, UA, UFAs
32  2021 Systematic investigation of the amino acid profiles that are correlated with xanthine oxidase inhibitory activity: Effects, mechanism and applications in protein source screening. ---
33  2021 The anti-hyperuricemic effects of green alga Enteromorpha prolifera polysaccharide via regulation of the uric acid transporters in vivo. EPP, NMR, UA
34  2021 The Extract of Sonneratia apetala Leaves and Branches Ameliorates Hyperuricemia in Mice by Regulating Renal Uric Acid Transporters and Suppressing the Activation of the JAK/STAT Signaling Pathway. BUN, CAT, CRE, GLUT9, HUA, HX, IL-18, IL-1beta, IL-6, JAK2, MCP-1, MDA, NF-kappaB, PO, SAL, SOCS3, SOD, STAT3, TGF-beta, UA, URAT1
35  2021 Withaferin A protects against hyperuricemia induced kidney injury and its possible mechanisms. ABCG2, BUN, GLUT9, OAT1, PO, UA, URAT1
36  2021 [Comprehensive antioxidant and anti-inflammatory activity of alcohol extracts from Chrysanthemum indicum in different areas based on entropy weight and TOPSIS methodology]. LOX
37  2021 [Preliminary study on effect of Phellinus igniarius ethanol extract on serum uric acid metabolism and gut microbiome in rats]. ADA, OAPS, SUA
38  2021 [Study on drug-target binding kinetics profiles of flavonoids in Chrysanthemum morifolium and xanthine oxidase]. SPR
39  2020 A natural complex product Yaocha reduces uric acid level in a live zebrafish model. OAT1, UA, XO
40  2020 Anti-Hyperuricemic Effects of Astaxanthin by Regulating Xanthine Oxidase, Adenosine Deaminase and Urate Transporters in Rats. ADA, AST, HUA, UA
41  2020 Antihyperuricemic efficacy of Scopoletin-loaded Soluplus micelles in yeast extract/potassium oxonate-induced hyperuricemic mice. OAT1, Sco, Sco-Ms
42  2020 Apilarnil: A Novel Neuroprotective Candidate. CAT, IL-1beta, IL-6, LPS, MDA, SOD, TNF-alpha
43  2020 Application of multi-dimensional and multi-informational (MD-MI) integrated xanthine oxidase and superoxide anion fingerprint in quality evaluation of Scutellariae Radix. MD-MI, SR, TCM
44  2020 Baicalein alleviates hyperuricemia by promoting uric acid excretion and inhibiting xanthine oxidase. BAL, PO, UA
45  2020 Beneficial Effects of Macroporous Resin Extract of Dendrobium candidum Leaves in Rats with Hyperuricemia Induced by a High-Purine Diet. ADA, DLE, HUA, UA
46  2020 Effects and Mechanisms of Dendrobium officinalis Six Nostrum for Treatment of Hyperuricemia with Hyperlipidemia. ADA, DOF, ELISA, HPA, HUA, IHC, LDL-C, LPL, PDZK1, PO, TC, UA
47  2020 Epigallocatechin gallate reduces uric acid levels by regulating xanthine oxidase activity and uric acid excretion in vitro and in vivo. EGCG
48  2020 Evaluation of Anticancer Activity of Satureja montana Supercritical and Spray-Dried Extracts on Ehrlich's Ascites Carcinoma Bearing Mice. CAT, EAC, GR, GSH-Px, LPx
49  2020 Evaluation of xanthine oxidase inhibitory activity of flavonoids by an online capillary electrophoresis-based immobilized enzyme microreactor. IMER
50  2020 Flexible enzyme cascade sensing platform based on a G-quadruplex nanofiber biohydrogel for target colorimetric sensing. FECS, GOD
51  2020 Flourensia fiebrigii S.F. blake: A medicinal plant from the Argentinean highlands with potential use as anti-rheumatic and anti-inflammatory. LOX, sPLA2
52  2020 Four new prenylflavonol glycosides from the leaves of Cyclocarya paliurus. LPS, NO
53  2020 Inulin supplementation ameliorates hyperuricemia and modulates gut microbiota in Uox-knockout mice. PCS, SCFA, UA, WT, ZO-1
54  2020 Isoorientin exerts a urate-lowering effect through inhibition of xanthine oxidase and regulation of the TLR4-NLRP3 inflammasome signaling pathway. BUN, CRE, CTSB, IL-18, ISO, TLR4, UA
55  2020 Lifeceramics-treated water reduces serum uric acid levels and improves hemorheological activity in hyperuricemic rats. AP, HUA, LC, LC water, PO, SUA
56  2020 Lung injury induced by short-term mechanical ventilation with hyperoxia and its mitigation by deferoxamine in rats. DFO, GR, SP-C, SP-D
57  2020 Lycium barbarum polysaccharides protect mice from hyperuricaemia through promoting kidney excretion of uric acid and inhibiting liver xanthine oxidase. GLUT9, OAT1, OAT3, SUA, UUA
58  2020 Metabolic mechanism and anti-inflammation effects of sinomenine and its major metabolites N-demethylsinomenine and sinomenine-N-oxide. SIN, SNO
59  2020 New prenylflavonol glycosides with xanthine oxidase inhibitory activity from the leaves of Cyclocarya paliurus. ---
60  2020 Paper-Based Enzyme Biosensor for One-Step Detection of Hypoxanthine in Fresh and Degraded Fish. HX, NBT
61  2020 Protective Effects of Biscoclaurine Alkaloids on Leukopenia Induced by 60Co-gamma Radiation. BA, IFN-gamma, MDA, SOD, VCAM-1, WBC
62  2020 The effect of Panax notoginseng saponins on oxidative stress induced by PCV2 infection in immune cells: in vitro and in vivo studies. iNOS, MPO, NO, PCV2, PNS, ROS
63  2020 Three-dimensional donor-acceptor-type photoactive material/conducting polyaniline hydrogel complex for sensitive photocathodic enzymatic bioanalysis. PAniHs
64  2020 [Study on mechanism of Fangji Huangqi Decoction on hypouricemic effect and renal protection in hyperuricemia mice]. beta2-MG, EGFR, FHT, HUA, IL-1beta, LRRK1, NF-kappaB, OAT1, PDZK1, URAT1
65  2019 Alteration of the Antioxidant Capacity and Gut Microbiota under High Levels of Molybdenum and Green Tea Polyphenols in Laying Hens. ALT, AST, GSH-ST, MDA, Mo, T-AOC, TP
66  2019 Antihyperuricemic effect of dietary polyphenol sinapic acid commonly present in various edible food plants. SA
67  2019 ATMP-induced three-dimensional conductive polymer hydrogel scaffold for a novel enhanced solid-state electrochemiluminescence biosensor. ANI, ATMP, ECL, PANI
68  2019 Comprehensive analysis of mechanism underlying hypouricemic effect of glucosyl hesperidin. GH, SUA
69  2019 Curcumin attenuates potassium oxonate-induced hyperuricemia and kidney inflammation in mice. BUN, CRE, CUR, PO, UA
70  2019 Development of a highly sensitive xanthine oxidase-based biosensor for the determination of antioxidant capacity in Amazonian fruit samples. PB
71  2019 Dihydrocaffeic Acid Prevents UVB-Induced Oxidative Stress Leading to the Inhibition of Apoptosis and MMP-1 Expression via p38 Signaling Pathway. CAT, DHCA, MAPK, MMP, ROS, SOD
72  2019 Effects of Alismatis Rhizoma and Rhizoma Smilacis Glabrae Decoction on Hyperuricemia in Rats. AR, HUA, RSG, UA, URAT1
73  2019 Effects of ChondroT on potassium Oxonate-induced Hyperuricemic mice: downregulation of xanthine oxidase and urate transporter 1. BUN, Cr, mURAT1, PO, UA
74  2019 Enhancement of Oral Bioavailability and Anti-hyperuricemic Activity of Isoliquiritigenin via Self-Microemulsifying Drug Delivery System. ISL, ISL-SMEDDS, SMEDDS
75  2019 Enhancing Effect on Radical Scavenging Activity of Edible Brown Alga, Laminaria japonica (Ma-konbu) by Roasting Treatment. DPPH, HPX, OPZ, ROS
76  2019 Forster Resonance Energy Transfer-Based Fluorescent Probe for the Selective Imaging of Hydroxylamine in Living Cells. HA
77  2019 Hypouricemic and nephroprotective roles of anthocyanins in hyperuricemic mice. ACNs, BUN, HUA, IL-1beta, SCr, SUA, TNF-alpha
78  2019 Ku86 alleviates human umbilical vein endothelial cellular apoptosis and senescence induced by a low dose of ionizing radiation. HUVECs, SOD2
79  2019 Lychnophora pinaster ethanolic extract and its chemical constituents ameliorate hyperuricemia and related inflammation. ---
80  2019 Modified Chuanhu anti-gout mixture, a traditional Chinese medicine, protects against potassium oxonate-induced hyperuricemia and renal dysfunction in mice. CAGM, PO, URAT1
81  2019 Novel urate transporter 1 (URAT1) inhibitors: a review of recent patent literature (2016-2019). URAT1
82  2019 Oxidative Status before and after Renal Replacement Therapy: Differences between Conventional High Flux Hemodialysis and on-Line Hemodiafiltration. HFD, OL-HDF, oxLDL, TAC
83  2019 Peroxiredoxin 6 knockout aggravates cecal ligation and puncture-induced acute lung injury. ALI, BALF, CAT, CLP, GSH-Px, IL, MDA, MMP, MPO, NF, PRDX, SOD, T-AOC
84  2019 Protective Effects of alpha-Lipoic Acid on Vascular Oxidative Stress in Rats with Hyperuricemia. ALA, BUN, CAT, CREA, GSH-Px, HDL-C, HUA, LDL-C, MDA, SOD, TC, UA
85  2019 Screening, and identification of the binding position, of xanthine oxidase inhibitors in the roots of Lindera reflexa Hemsl using ultrafiltration LC-MS combined with enzyme blocking. LC-MS, LR
86  2019 The anti-hyperuricemic effect of four astilbin stereoisomers in Smilax glabra on hyperuricemic mice. BUN, OAT1, OCTN2, SCr, SUA, TFSG
87  2019 Two new phenylpropanoid glycosides from Lagotis brachystachya Maxim and their Xanthione Oxidase inhibitions. ---
88  2019 Two symmetrical unsaturated acids isolated from Viscum album. DPPH
89  2019 Xanthine oxidase inhibitor ameliorates postischemic renal injury in mice by promoting resynthesis of adenine nucleotides. 10mIR
90  2019 [Astragalus polysaccharide inhibits autophagy and regulates expression of autophagy-related proteins in lung cancer A549 cells induced by xanthine oxidase]. APS, LC3B, MDC, mTOR, TEM
91  2018 4-(2-(4-chlorophenyl)-1-((4-chlorophenyl)amino)ethyl)benzene-1, 3-diol is a potential agent for gout therapy as a dual inhibitor of XOD and NLRP3. ASC, CBED, IL, MSU, NLRP3
92  2018 A novel amperometric enzyme inhibition biosensor based on xanthine oxidase immobilised onto glassy carbon electrodes for bisphenol A determination. BPA
93  2018 A novel IgG1 monoclonal antibody against xanthine oxidase alleviates inflammation induced by potassium oxonate in mice. ---
94  2018 Actions of Inonotus obliquus against Hyperuricemia through XOD and Bioactives Screened by Molecular Modeling. SUA, URAT1
95  2018 Anti-hyperuricemic and anti-gouty arthritis activities of polysaccharide purified from Lonicera japonica in model rats. ---
96  2018 Anti-Hyperuricemic Effect of 2-Hydroxy-4-methoxy-benzophenone-5-sulfonic Acid in Hyperuricemic Mice through XOD. GLUT9, HMS, OAT1
97  2018 Anti-hyperuricemic peptides derived from bonito hydrolysates based on in vivo hyperuricemic model and in vitro xanthine oxidase inhibitory activity. BH, DWH, PO, SH
98  2018 Antihyperuricemic effect of mangiferin aglycon derivative J99745 by inhibiting xanthine oxidase activity and urate transporter 1 expression in mice. ABCG2, BUN, FEUA, GLUT9, MDA, OAT1, PCR, URAT1
99  2018 Antimicrobial and antiurease potential of Diorganotin(IV) Schiff bases. AA, DPPH, EE, ORAC
100  2018 Antioxidant and xanthine oxidase inhibitory activity of Eucommia ulmoides Oliver leaf extracts. AA, DPPH, EE, ORAC