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Abbreviation : miR-21
Long Form : microRNA-21
No. Year Title Co-occurring Abbreviation
2022 A dual-amplification mode and Cu-based metal-organic frameworks mediated electrochemical biosensor for sensitive detection of microRNA. CHA, Cu-MOFs, EC, HCR, miRNA
2022 A functionalized collagen-I scaffold delivers microRNA 21-loaded exosomes for spinal cord injury repair. CBD, Col I, Lamp2b, miRNA, SCI
2022 A Prussian blue nanoparticles-based fluorescent nanoprobe for monitoring microRNA-92a and microRNA-21. CRC, Cy5, miR-92a, PBNPs
2022 An Ultrasensitive Electrochemical Biosensor Integrated by Nicking Endonuclease-Assisted Primer Exchange Reaction Cascade Amplification and DNA Nanosphere-Mediated Electrochemical Signal-Enhanced System for MicroRNA Detection. cDNA, DNS, DP, miRNAs, PER, sDNA
2022 Anti-microRNA-21 Therapy on Top of ACE Inhibition Delays Renal Failure in Alport Syndrome Mouse Models. ACEi, ACEi
2022 Anti-PD-L1 Antibody Enhances T Cell Immune Responses and Reduces Resistance of Breast Cancer Cells to Radiotherapy. BC, PD-L1, PDCD4
2022 Arsenic activates STAT3 signaling during the transformation of the human bronchial epithelial cells. pSTAT3S727, pSTAT3Y705, SHP-1
2022 Association between genetic variants of microRNA-21 and microRNA-155 and systemic lupus erythematosus: A case-control study from a Chinese population. CIs, miR-155, ORs, RT-qPCR, SLE
2022 Chitosan/Hyaluronic Acid/MicroRNA-21 Nanoparticle-Coated Smooth Titanium Surfaces Promote the Functionality of Human Gingival Fibroblasts. CS, HA, TPP
10  2022 Circulating exosomal miR-21 mediates HUVEC proliferation and migration through PTEN/PI3K/AKT in Crohn's disease. AKT, CD, HIF-1alpha, HUVECs, PI3K, PTEN, qPCR, VEGF
11  2022 Comparison of serum biomarkers of myocardial fibrosis with cardiac magnetic resonance in patients operated for tetralogy of Fallot. CMR, IQR, LV, PVR, TOF
12  2022 Deletion of MicroRNA-21 Impairs Neovascularization Following Limb Ischemia: From Bedside to Bench. MALEs, PAD
13  2022 DNA Logic Nanodevices for the Sequential Imaging of Cancer Markers through Localized Catalytic Hairpin Assembly Reaction. CHA, DT, MUC1, MUC1-apt, TDLNs
14  2022 Dynamic Changes in miR-21 Regulate Right Ventricular Dysfunction in Congenital Heart Disease-Related Pulmonary Arterial Hypertension. AVS, HF, PAH, RV
15  2022 Exosome-Mediated miR-21 Was Involved in the Promotion of Structural and Functional Recovery Effect Produced by Electroacupuncture in Sciatic Nerve Injury. EA
16  2022 Exosomes derived from microRNA-21 overexpressed adipose tissue-derived mesenchymal stem cells alleviate spine osteoporosis in ankylosing spondylitis mice. AD-MSCs, AS, IL, MSCs, PGIA, TRACP
17  2022 Fabrication of a Free-Standing MWCNT Electrode by Electric Field Force for an Ultra-Sensitive MicroRNA-21 Nano-Genosensor. MWCNTs
18  2022 Gender Differential Expression of AR/miR-21 Signaling Axis and Its Protective Effect on Renal Ischemia-Reperfusion Injury. AR
19  2022 Genosensors, a nanomaterial-based platform for microRNA-21 detection, non-invasive methods in early detection of cancer. ---
20  2022 HPV-Induced MiR-21 Promotes Epithelial Mesenchymal Transformation and Tumor Progression in Cervical Cancer Cells through the TGFβ R2/hTERC Pathway. CC, EMT, HPV
21  2022 Hydrogen sulfide and miR21 are suitable biomarkers of hypoxic exposure. ET-1
22  2022 Macrophage-targeting gene silencing orchestrates myocardial microenvironment remodeling toward the anti-inflammatory treatment of ischemia-reperfusion (IR) injury. IR, NCs, siMOF
23  2022 Mechanism of the switch from NO to H2O2 in endothelium-dependent vasodilation in diabetes. CAD, EDD, L-NAME, MBF, NO, WT
24  2022 Melatonin promotes apoptosis of thyroid cancer cells via regulating the signaling of microRNA-21 (miR-21) and microRNA-30e (miR-30e). CASC7, IHC, MEL, miR-30e, PTEN
25  2022 Mesenchymal stem cell-derived exosome-educated macrophages alleviate systemic lupus erythematosus by promoting efferocytosis and recruitment of IL-17+ regulatory T cell. Arg-1, BM-MSCs, iNOS, miR-16, ROS, SLE, Treg
26  2022 MicroRNA-21 as a potential biomarker for detecting esophageal carcinoma in Asian populations: a meta-analysis. DOR, EC, NLR, PLR, QUADAS-2, SEN, SPE
27  2022 MicroRNA-21 expression in single living cells revealed by fluorescence and SERS dual-response microfluidic droplet platform. ---
28  2022 MicroRNA-21 induces cisplatin resistance in head and neck squamous cell carcinoma. HNC, HNSCC, NC, PTEN
29  2022 MicroRNA-21 promotes epithelial-mesenchymal transition and migration of human bronchial epithelial cells by targeting poly (ADP-ribose) polymerase-1 and activating PI3K/AKT signaling. EMT, siRNA
30  2022 MicroRNA-21: A Critical Pathogenic Factor of Diabetic Nephropathy. DN
31  2022 MIP From Legionella pneumophila Influences the Phagocytosis and Chemotaxis of RAW264.7 Macrophages by Regulating the lncRNA GAS5/miR-21/SOCS6 Axis. L. pneumophila, lncRNA, mip, SOCS
32  2022 miR-21 antagonist alleviates colitis and angiogenesis via the PTEN/PI3K/AKT pathway in colitis mice induced by TNBS. CD, CD31, DAI, ELISA, IL-1beta, PI3K, PTEN, RNase, TNBS, TNF-alpha, VEGF
33  2022 MiR-21 in Lung Transplant Recipients With Chronic Lung Allograft Dysfunction. BOS, CLAD, EMT, NICD, RAS
34  2022 miR-21 promotes the fibrotic properties in oral mucosa through targeting PDCD4. fBMFs, OSF, PDCD4
35  2022 miR21 deletion in osteocytes has direct and indirect effects on skeletal muscle in a sex-dimorphic manner in mice. OtmiR21Delta
36  2022 miR21 modulates the Hippo signaling pathway via interference with PP2A Bβ to inhibit trophoblast invasion and cause preeclampsia. EVT, PE
37  2022 miRNA-21 regulates CD69 and IL-10 expression in canine leishmaniasis. CanL
38  2022 Onco-miR-21 Promotes Stat3-Dependent Gastric Cancer Progression. ---
39  2022 Paper-Based Devices for Capturing Exosomes and Exosomal Nucleic Acids From Biological Samples. ELISA, miRNAs, POCT, RT-qPCR
40  2022 Potential Values of Circulating microRNA-21 to Predict Early Recurrence in Patients with Colorectal Cancer after Treatments. CA19-9, CEA, CRC
41  2022 Protective Effects of PPARγ on Renal Ischemia-Reperfusion Injury by Regulating miR-21. PDCD4, PPARgamma, RIRI
42  2022 Rapid and ultrasensitive detection of DNA and microRNA-21 using a zirconium porphyrin metal-organic framework-based switch fluorescence biosensor. dsDNA, FRET, PET, ssDNA, ZrMOF
43  2022 Regulatory network identified by pulmonary transcriptome and proteome profiling reveals extensive change of tumor-related genes in microRNA-21 knockout mice. DEGs, KO, WT
44  2022 Relation of circulating lncRNA GAS5 and miR-21 with biochemical indexes, stenosis severity, and inflammatory cytokines in coronary heart disease patients. CHD, CRP, IL, IQR, lnc-GAS5, TNF-alpha
45  2022 Relationship between circulating miRNA-21, atrial fibrosis, and atrial fibrillation in patients with atrial enlargement. AF, AUC, CI, LA, miRNAs, MRI, qRT-PCR, ROC, SR, TTE
46  2022 Revisiting miRNA-21 as a Therapeutic Strategy for Myocardial Infarction: A Systematic Review. ---
47  2022 Roles of MicroRNA-21 in Skin Wound Healing: A Comprehensive Review. ---
48  2022 Sensitive fluorescent detection of exosomal microRNA based on enzymes-assisted dual-signal amplification. CP, DSN, GC, miRNAs, PC
49  2022 Splenic Marginal Zone B Lymphocytes Regulate Cardiac Remodeling After Acute Myocardial Infarction in Mice. HIF-alpha, MI, MZB
50  2022 Tangeretin Synergizes with 5-Fluorouracil to Induce Autophagy through MicroRNA-21 in Colorectal Cancer Cells. 5-FU, CRC, HTS
51  2022 The clinical value of miRNA-21 in cervical cancer: A comprehensive investigation based on microarray datasets. CC, GEO, mTOR
52  2022 Transcription Factor FOXO3a Overexpression Inhibits the Progression of Neuroblastoma by Regulating the miR-21/SPRY2/ERK Axis. ERK
53  2022 Tuning Surface Properties via Plasma Treatments for the Improved Capture of MicroRNA Biomarkers. ---
54  2022 Upconversion Nanoparticle@Au Core-Satellite Assemblies for In Situ Amplified Imaging of MicroRNA in Living Cells and Combined Cancer Phototherapy. miRNA, PDT, PTT, RB, TMSD, UCL
55  2022 [Role and mechanism of signal transducer and activator of transcription protein STAT1/3/5 in hyperoxia-induced acute lung injury]. ELISA, HALI, MDA, MMP-9, NEU, RT-PCR, SOD, TNF-alpha
56  2021 A Deoxyribozyme-Initiated Self-Catalytic DNA Machine for Amplified Live-Cell Imaging of MicroRNA. CSA, SDA
57  2021 A nanoprobe for fluorescent monitoring of microRNA and targeted delivery of drugs. DOX, MOFs, NIR, UCNPs
58  2021 A One-Two-Three Multifunctional System for Enhanced Imaging and Detection of Intracellular MicroRNA and Chemogene Therapy. ---
59  2021 A persistent luminescence resonance energy transfer-based molecular beacon probe for the highly sensitive detection of microRNA in biological samples. MB, NIR, PAA, PL, PLNPs, TR-LRET
60  2021 A signal-on fluorescence-based strategy for detection of microRNA-21 based on graphene oxide and lamda exonuclease-based signal amplification. GO, miRNA, ssDNA
61  2021 Brief report: Lymph node morphology in stage II colorectal cancer. ---
62  2021 Calcium phosphate-polymeric nanoparticle system for co-delivery of microRNA-21 inhibitor and doxorubicin. CaP, DOX, NP
63  2021 Cancer-associated fibroblasts induce monocytic myeloid-derived suppressor cell generation via IL-6/exosomal miR-21-activated STAT3 signaling to promote cisplatin resistance in esophageal squamous cell carcinoma. ESCC, IL, M-MDSCs, STAT3
64  2021 Curcumin protects against inflammation and lung injury in rats with acute pulmonary embolism with the involvement of microRNA-21/PTEN/NF-kappaB axis. APE
65  2021 Dairy consumption and hepatocellular carcinoma risk. BCAAs, HBV, HCC, HCV, IGF-1, mTORC1, T2DM
66  2021 Deviations in MicroRNA-21 Expression Patterns Identify a Therapeutic Target for Diabetic Wound Healing. ---
67  2021 Direct detection of intracellular miRNA in living circulating tumor cells by tumor targeting nanoprobe in peripheral blood. CHA, CTCs, HA, PS
68  2021 DNAzyme cascade circuits in highly integrated DNA nanomachines for sensitive microRNAs imaging in living cells. DTP, miRNAs
69  2021 Downregulation of microRNA-21 contributes to decreased collagen expression in venous malformations via transforming growth factor-β/Smad3/microRNA-21 signaling feedback loop. HUVECs, TGF-beta, VMs
70  2021 Endogenous microRNA triggered enzyme-free DNA logic self-assembly for amplified bioimaging and enhanced gene therapy via in situ generation of siRNAs. DNWs, FRET, siRNA, VEGF
71  2021 Exosomal MicroRNA-21 Promotes Keloid Fibroblast Proliferation and Collagen Production by Inhibiting Smad7. ---
72  2021 Expression of microRNA-21 and TIMP-3 in paradoxical psoriasiform reactions during treatment with antitumor necrosis factor agents. TIMP-3, TNF-alpha
73  2021 Expression of microRNA-21 in saliva and tumor tissue of patients with oral squamous cell carcinoma: a predictor of cervical lymph node metastasis. OSCC
74  2021 Expression Pattern of MicroRNA-21 during the Liver Ischemia/Reperfusion. ALP, AST, FASL, I/R, PDCD4, RT-PCR, TAC, TIA1
75  2021 Hematocrit-Related Alterations of Circulating microRNA-21 Levels in Heart Failure Patients with Reduced Ejection Fraction: A Preliminary Study. H-score, HF
76  2021 Hyperoside prevents sepsis-associated cardiac dysfunction through regulating cardiomyocyte viability and inflammation via inhibiting miR-21. CLP, Hyp, LPS
77  2021 Immobilising hairpin DNA-conjugated distyryl boron dipyrromethene on gold@polydopamine core-shell nanorods for microRNA detection and microRNA-mediated photodynamic therapy. DSBDP
78  2021 Intranasal delivery of self-assembled nanoparticles of therapeutic peptides and antagomirs elicits anti-tumor effects in an intracranial glioblastoma model. RAGE, RAP
79  2021 Kidney microRNA-21 Expression and Kidney Function in IgA Nephropathy. IgAN
80  2021 Lithocholic Acid Induces miR21, Promoting PTEN Inhibition via STAT3 and ERK-1/2 Signaling in Colorectal Cancer Cells. CRC, LCA, PTEN
81  2021 Living-Cell MicroRNA Imaging with Self-Assembling Fragments of Fluorescent Protein-Mimic RNA Aptamer. DFHO, RIFC
82  2021 Long non-coding RNA BRE-AS1 inhibits the proliferation, migration, and invasion of cancer cells in triple-negative breast cancer and predicts patients' survival by downregulating miR-21. TNBC
83  2021 Macrophage-Derived MicroRNA-21 Drives Overwhelming Glycolytic and Inflammatory Response during Sepsis via Repression of the PGE2/IL-10 Axis. ---
84  2021 micro-RNA 21 detection with a limit of 2 pM in 1min using a size-accordable concentration module operated by electrohydrodynamic actuation. MB, RT-PCR
85  2021 microRNA-21 ameliorates the impairment of autophagy in palatal wound healing. ATG5, Beclin1, ECM, GMSCs, HGFs, WT
86  2021 MicroRNA-21 Deficiency Promotes the Early Th1 Immune Response and Resistance toward Visceral Leishmaniasis. miR-21KO, VL
87  2021 MicroRNA-21 deficiency suppresses prostate cancer progression through downregulation of the IRS1-SREBP-1 signaling pathway. ACC, FASN, IRS-1, MEFs, PCa, SREBP-1
88  2021 MicroRNA-21 expression in cancer cells is an independent biomarker of progression-free survival of endometrioid endometrial carcinoma. FIGO, ISH, LNA
89  2021 MicroRNA-21 Inhibition Suppresses Alveolar M2 Macrophages in an Ovalbumin-Induced Allergic Asthma Mice Model. AHR, BALF, IFN, IHC, IL, KO, OVA
90  2021 MicroRNA-21 mediates the protective role of emulsified isoflurane against myocardial ischemia/reperfusion injury in mice by targeting SPP1. EI, I/R, SPP1
91  2021 MicroRNA-21 Plays Multiple Oncometabolic Roles in Colitis-Associated Carcinoma and Colorectal Cancer via the PI3K/AKT, STAT3, and PDCD4/TNF-alpha Signaling Pathways in Zebrafish. CAC, CRC, IBD
92  2021 MicroRNA-21 Plays Multiple Oncometabolic Roles in the Process of NAFLD-Related Hepatocellular Carcinoma via PI3K/AKT, TGF-β, and STAT3 Signaling. DEN, DOX, HCC, HSC, NAFLD, NASH
93  2021 MicroRNA-21-containing microvesicles from tubular epithelial cells promote cardiomyocyte hypertrophy. CKD, CVD, MVs
94  2021 MicroRNA-21-Dependent Macrophage-to-Fibroblast Signaling Determines the Cardiac Response to Pressure Overload. cMPs
95  2021 MicroRNA-21: An Emerging Player in Bone Diseases. MiRNAs, OA
96  2021 MiR-21 Is Required for the Epithelial-Mesenchymal Transition in MDA-MB-231 Breast Cancer Cells. BCa, EMT, EVs
97  2021 miR-21 regulates ischemic neuronal injury via the p53/Bcl-2/Bax signaling pathway. ---
98  2021 Mir-21 Suppression Promotes Mouse Hepatocarcinogenesis. HCC
99  2021 MiR-21-3p Inhibits Adipose Browning by Targeting FGFR1 and Aggravates Atrial Fibrosis in Diabetes. AF, EAT, FGFR
100  2021 miR-21-regulated M2 polarization of macrophage is involved in arsenicosis-induced hepatic fibrosis through the activation of hepatic stellate cells. Arg1, p-mTOR, PTEN, THP-M