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Abbreviation : non-Tg
Long Form : non-transgenic
No. Year Title Co-occurring Abbreviation
2020 The effects of voluntary running on cerebrovascular morphology and spatial short-term memory in a mouse model of amyloidosis. AD, MCI, Tg
2019 Blast-Mediated Traumatic Brain Injury Exacerbates Retinal Damage and Amyloidosis in the APPswePSENd19e Mouse Model of Alzheimer's Disease. AD, APP, cPLR, Non-TG-Blast, OCT, PERG, RGC, TBI, Tg
2019 Glutathione peroxidase-1 gene rescues cocaine-induced conditioned place preference in mice by inhibiting sigma-1 receptor expression. c-Fos-IR, CPP, GPx-1, GPx-1 KO, GPx-1 TG, NAc, WT
2019 Human tau pathology transmits glial tau aggregates in the absence of neuronal tau. AD, CBD, PSP
2019 Isoflurane mediated neuropathological and cognitive impairments in the triple transgenic Alzheimer's mouse model are associated with hippocampal synaptic deficits in an age-dependent manner. AD, CA1, ISO, LTP, MWM, PPF
2019 Mitochondrial Movement and Number Deficits in Embryonic Cortical Neurons from 3xTg-AD Mice. AD
2019 Overexpression of glutathione peroxidase-1 attenuates cocaine-induced reproductive dysfunction in male mice by inhibiting nuclear factor kappaB. GPx, GPx-1 KO, GPx-1 TG, NF-kappaB, PDTC, WT
2019 Oxidation of KCNB1 potassium channels in the murine brain during aging is associated with cognitive impairment. MWM
2018 Altered brain activity during withdrawal from chronic alcohol is associated with changes in IL-6 signal transduction and GABAergic mechanisms in transgenic mice with increased astrocyte expression of IL-6. EEG, GABAAR, IL-6
10  2018 Altered hippocampal synaptic function in transgenic mice with increased astrocyte expression of CCL2 after withdrawal from chronic alcohol. LTP
11  2018 Astrocytic mobilization of glutathione peroxidase-1 contributes to the protective potential against cocaine kindling behaviors in mice via activation of JAK2/STAT3 signaling. GFAP, GPX1
12  2018 Characterization of a 3xTg-AD mouse model of Alzheimer's disease with the senescence accelerated mouse prone 8 (SAMP8) background. AD, GFAP, NeuN, SAMP8
13  2018 Genetic overexpression of glutathione peroxidase-1 attenuates microcystin-leucine-arginine-induced memory impairment in mice. GPx, GPx-1 Tg, i.c.v, MCLR, Nrf2, SOD
14  2018 Supragranular Pyramidal Cells Exhibit Early Metabolic Alterations in the 3xTg-AD Mouse Model of Alzheimer's Disease. AD, FRET, scRT-mPCR
15  2018 Temporal and regional progression of Alzheimer's disease-like pathology in 3xTg-AD mice. AD
16  2017 Dyrk1 inhibition improves Alzheimer's disease-like pathology. AD, APP, Dyrk1a
17  2017 Loss of Parkin reduces inflammatory arthritis by inhibiting p53 degradation. KO, PD, RA
18  2017 Pathological Tau Strains from Human Brains Recapitulate the Diversity of Tauopathies in Nontransgenic Mouse Brain. AD, AD
19  2017 Rapamycin-Sensitive Late-LTP is Enhanced in the Hippocampus of IL-6 Transgenic Mice. CNS, LTP, mTOR
20  2016 Identification of learning-induced changes in protein networks in the hippocampi of a mouse model of Alzheimer's disease. AD, iTRAQ
21  2016 Mitochondrial Abnormalities and Synaptic Loss Underlie Memory Deficits Seen in Mouse Models of Obesity and Alzheimer's Disease. AD
22  2016 Monitoring of Venus transgenic cell migration during pregnancy in non-transgenic rabbits. gDNA, PBMCs, qPCR, Tg
23  2016 Redox Proteomic Profiling of Specifically Carbonylated Proteins in the Serum of Triple Transgenic Alzheimer's Disease Mice. AD, ELISA, IGKC, IGLC2
24  2016 Severe hypertriglyceridemia does not protect from ischemic brain injury in gene-modified hypertriglyceridemic mice. GPIHBP1, HTG, tMCAO
25  2016 Suppression of glucose-6-phosphate-isomerase induced arthritis by oral administration of transgenic rice seeds expressing altered peptide ligands of glucose-6-phosphate-isomerase. APL, APL12-TG, GIA, hGPI325-339-TG, ILN
26  2015 Age-dependent impairment of glucose tolerance in the 3xTg-AD mouse model of Alzheimer's disease. AD
27  2015 Circadian Disruption Reveals a Correlation of an Oxidative GSH/GSSG Redox Shift with Learning and Impaired Memory in an Alzheimer's Disease Mouse Model. AD, AD
28  2015 Multi-target iron-chelators improve memory loss in a rat model of sporadic Alzheimer's disease. MWM, PA, SAD
29  2015 NR2B-dependent cyclophilin D translocation suppresses the recovery of synaptic transmission after oxygen-glucose deprivation. CsA, CypD, mPTP, NMDA, OGD
30  2015 Transgenic mice with increased astrocyte expression of IL-6 show altered effects of acute ethanol on synaptic function. CNS, fEPSP, IL-6, IL-6-tg, PS
31  2015 Transient Cerebral Ischemia Promotes Brain Mitochondrial Dysfunction and Exacerbates Cognitive Impairments in Young 5xFAD Mice. AD, Mfn2, OPA1
32  2014 Age-related decline in white matter integrity in a mouse model of tauopathy: an in vivo diffusion tensor magnetic resonance imaging study. AD, DT-MRI, FA, WM
33  2014 Alzheimer disease in a mouse model: MR imaging-guided focused ultrasound targeted to the hippocampus opens the blood-brain barrier and improves pathologic abnormalities and behavior. MR
34  2014 Dominant negative connexin26 mutation R75W causing severe hearing loss influences normal programmed cell death in postnatal organ of Corti. GER, GJB2
35  2014 Extensive dysregulations of oligodendrocytic and astrocytic connexins are associated with disease progression in an amyotrophic lateral sclerosis mouse model. ALS, AQP4, Cxs, EAAT2, GFAP, GJs, MOG, mSOD1, mSOD1-Tg
36  2014 Microglial response to Alzheimer's disease is differentially modulated by voluntary wheel running and enriched environments. AD, ENR, RUN, S.Mol, STD
37  2013 Altered regional cardiac wall mechanics are associated with differential cardiomyocyte calcium handling due to nebulette mutations in preclinical inherited dilated cardiomyopathy. CMR, DCM, NEBL, Tg
38  2013 Dual-energy precursor and nuclear erythroid-related factor 2 activator treatment additively improve redox glutathione levels and neuron survival in aging and Alzheimer mouse neurons upstream of reactive oxygen species. AD, GCL, Nrf2, ROS
39  2013 Early decline in glucose transport and metabolism precedes shift to ketogenic system in female aging and Alzheimer's mouse brain: implication for bioenergetic intervention. ---
40  2013 Enhanced synthesis and release of dopamine in transgenic mice with gain-of-function alpha6* nAChRs. DA, NAc, nAChRs, NE
41  2013 Mechanical and energetic properties of papillary muscle from ACTC E99K transgenic mouse models of hypertrophic cardiomyopathy. ---
42  2013 Proliferation, differentiation and amyloid-beta production in neural progenitor cells isolated from TgCRND8 mice. APP
43  2013 Tumor promotion by 12-O-tetradecanoylphorbol-13-acetate in an ultra-short-term skin carcinogenesis bioassay using rasH2 mice. DMBA, Tg, TPA
44  2013 Ultrahigh resolution mass spectrometry-based metabolic characterization reveals cerebellum as a disturbed region in two animal models. TCDD, Tg
45  2012 A reversible early oxidized redox state that precedes macromolecular ROS damage in aging nontransgenic and 3xTg-AD mouse neurons. AD, ROS
46  2012 Age-related changes in core body temperature and activity in triple-transgenic Alzheimer's disease (3xTgAD) mice. AD
47  2012 Altered synaptic transmission in the hippocampus of transgenic mice with enhanced central nervous systems expression of interleukin-6. IL-6, IL-6 tg
48  2012 Early presynaptic and postsynaptic calcium signaling abnormalities mask underlying synaptic depression in presymptomatic Alzheimer's disease mice. AD, LTD, LTP, PS, RyR
49  2012 Enhanced expression of glia maturation factor correlates with glial activation in the brain of triple transgenic Alzheimer's disease mice. GMF, Iba-1, IFN-gamma, IL-6, TNF-alpha
50  2012 Expression of human CD46 has no effect on porcine circovirus type 2 infection and shedding in the experimental pig model. CD46, dpi, PCV2
51  2012 High tryptophan diet reduces CA1 intraneuronal beta-amyloid in the triple transgenic mouse model of Alzheimer's disease. AD, HTrP, S.Mol, SERT
52  2011 Allopregnanolone restores hippocampal-dependent learning and memory and neural progenitor survival in aging 3xTgAD and nonTg mice. AD
53  2011 Focal cerebral ischemia and mitochondrial dysfunction in the TNFalpha-transgenic rat. MCAO, TNF-alpha, TNFalpha-Tg
54  2011 Multi-faced neuroprotective effects of Ginsenoside Rg1 in an Alzheimer mouse model. AD, APP
55  2011 Notch activation enhances the microglia-mediated inflammatory response associated with focal cerebral ischemia. GSI, Tg
56  2011 Ovarian hormone loss induces bioenergetic deficits and mitochondrial beta-amyloid. ABAD, AD
57  2011 Voluntary running and environmental enrichment restores impaired hippocampal neurogenesis in a triple transgenic mouse model of Alzheimer's disease. AD, ENR, HH3, NeuN, RUN
58  2010 A maladaptive role for EP4 receptors in podocytes. ---
59  2010 Increase in the density of resting microglia precedes neuritic plaque formation and microglial activation in a transgenic model of Alzheimer's disease. AD
60  2009 Deviant ryanodine receptor-mediated calcium release resets synaptic homeostasis in presymptomatic 3xTg-AD mice. AD, ER, RyR
61  2009 Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease. ABAD, AD, PDH
62  2008 Focal cerebral ischemia in the TNFalpha-transgenic rat. LDF, MCAO, TNF-alpha
63  2008 GABA(A) receptor-mediated acceleration of aging-associated memory decline in APP/PS1 mice and its pharmacological treatment by picrotoxin. AD, APP, LTP, PTX
64  2008 Impaired adult neurogenesis in the dentate gyrus of a triple transgenic mouse model of Alzheimer's disease. AD, DG, HH3, SGZ
65  2007 Enhanced ryanodine-mediated calcium release in mutant PS1-expressing Alzheimer's mouse models. AD
66  2007 Overexpression of apolipoprotein CIII increases and CETP reverses diet-induced obesity in transgenic mice. apo
67  2007 Overexpression of dimethylarginine dimethylaminohydrolase inhibits asymmetric dimethylarginine-induced endothelial dysfunction in the cerebral circulation. ADMA, DDAH-1-Tg, DDAHs, NOS
68  2006 Adoptive transfer of nontransgenic mesenteric lymph node cells induces colitis in athymic HLA-B27 transgenic nude rats. MLN, Tg
69  2006 Enhanced ryanodine receptor recruitment contributes to Ca2+ disruptions in young, adult, and aged Alzheimer's disease mice. AD, ER, RyRs
70  2006 Identification of putative in vivo substrates of calpain 3 by comparative proteomics of overexpressing transgenic and nontransgenic mice. CAPN3, CAPN3, MLC1
71  2005 Lack of urinary bladder carcinogenicity of sodium L-ascorbate in human c-Ha-ras proto-oncogene transgenic rats. Tg
72  2004 Corticotropin-releasing factor overexpression decreases ethanol drinking and increases sensitivity to the sedative effects of ethanol. CRF, CTA, EtOH, LORR, Tg
73  2004 Overexpression of brain natriuretic peptide facilitates neutrophil infiltration and cardiac matrix metalloproteinase-9 expression after acute myocardial infarction. BNP, BNP-Tg, MI, MMP
74  2004 Overexpression of CuZn-SOD prevents lipopolysaccharide-induced endothelial dysfunction. ACh, LPS, SOD-Tg
75  2004 Reduced ratio of protective versus proinflammatory cytokine responses to commensal bacteria in HLA-B27 transgenic rats. CBL, MLN, SPF, Tg
76  2003 Constitutive over-expression of the insulin receptor substrate-1 causes functional up-regulation of Fas receptor. IRS-1, MAPK, PI3K, Tg
77  2003 Increased auditory startle response and reduced prepulse inhibition of startle in transgenic mice expressing a double mutant form of amyloid precursor protein. AD, PPI, Tg
78  2002 Age-independent and age-related deficits in visuospatial learning, sleep-wake states, thermoregulation and motor activity in PDAPP mice. REM, Tb
79  2002 Coordination between donor cell type and cell cycle stage improves nuclear cloning efficiency in cattle. BFFs, NT
80  2002 Inhibitory effects of 17beta-estradiol and 4-n-octylphenol on 7,12-dimethylbenz[a]anthracene-induced mammary tumor development in human c-Ha-ras proto-oncogene transgenic rats. 4-n-OP, DMBA, Tg
81  2002 Interleukin-5 transgenic mice show augmented resistance to Angiostrongylus costaricensis infection. IL-5, Tg
82  2001 Aberrant expression of cyclin D1 in pulmonary proliferative lesions induced by high doses of urethane in transgenic mice carrying the human prototype c-H-ras gene. ---
83  2001 Monoclonal antibody against brain natriuretic peptide and characterization of brain natriuretic peptide-transgenic mice. ANP, BNP, BP
84  2000 Age-related amyloid beta deposition in transgenic mice overexpressing both Alzheimer mutant presenilin 1 and amyloid beta precursor protein Swedish mutant is not associated with global neuronal loss. AD, CA1, FC, PS1
85  2000 Carcinogen dose-dependent variation in the transgene mutation spectrum in urethane-induced lung tumors in transgenic mice carrying the human prototype c-Ha-ras gene. Tg
86  1999 B7-1 overexpression by thymic epithelial cells results in transient and long-lasting effects on thymocytes and peripheral T helper cells but does not result in immunodeficiency. Tg
87  1999 Physiological roles of gammadelta T-cell receptor intraepithelial lymphocytes in cytoproliferation and differentiation of mouse intestinal epithelial cells. GF, IEL, IFN-gamma, LI, MHC, RT-PCR, SI, SPF, TCR
88  1999 Varying cecal bacterial loads influences colitis and gastritis in HLA-B27 transgenic rats. SFBL, sham, Tg
89  1997 Increased acute-phase response and renal amyloidosis in aged CD2-fas-transgenic mice. Fas-Tg
90  1996 Activation and negative selection of functionally distinct subsets of antibody-secreting cells by influenza hemagglutinin as a viral and a neo-self antigen. ASC, PR8 HA
91  1996 AP-1 DNA-binding activation by methamphetamine involves oxidative stress. METH, SOD-Tg
92  1996 Inhibition of diabetic nephropathy by a GH antagonist: a molecular analysis. Tg
93  1995 Methamphetamine-induced serotonin neurotoxicity is mediated by superoxide radicals. CuZnSOD, DA, homo, METH, Tg
94  1995 Neurotoxicity, drugs and abuse, and the CuZn-superoxide dismutase transgenic mice. DOPAC, METH
95  1995 Overexpression of the T-cell receptor V beta 3 in transgenic mice increases mortality during infection by enterotoxin A-producing Staphylococcus aureus. IL-1beta, TNF-alpha
96  1994 Autoradiographic distribution of mu opioid receptors in the brains of Cu/Zn-superoxide dismutase mice. SNpc, SOD, SOD-Tg, VTA
97  1994 Virus-specific CD8+ T-cell responses in mice transgenic for a T-cell receptor beta chain selected at random. CTL, TCR
98  1993 Immunopharmacology of the superantigen staphylococcal enterotoxin A in T-cell receptor V beta 3 transgenic mice. CTL, IFN-gamma, IL-1, MHC, RT-PCR, SEA, TCR, TNF-alpha