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Abbreviation : tMCAO
Long Form : transient middle cerebral artery occlusion
No. Year Title Co-occurring Abbreviation
2021 A longitudinal PET/MR imaging study of colony stimulating factor-1 receptor-mediated microglia depletion in experimental stroke. CSF-1R, MR, PET, TMEM119, TSPO
2021 A neutrophil-mimetic magnetic nanoprobe for molecular magnetic resonance imaging of stroke-induced neuroinflammation. NMNPs, PLGA, SPIO
2021 A novel PGAM5 inhibitor LFHP-1c protects blood-brain barrier integrity in ischemic stroke. BBB
2021 Astragaloside IV promotes microglia/macrophages M2 polarization and enhances neurogenesis and angiogenesis through PPARγ pathway after cerebral ischemia/reperfusion injury in rats. AS-IV, BDNF, IGF-1, PPARgamma, VEGF
2021 Autophagy Elicits Neuroprotection at the Subacute Phase of Transient Cerebral Ischaemia but Has Few Effects on Neurological Outcomes After Permanent Ischaemic Stroke in Rats. pMCAO
2021 Autophagy is Involved in Neuroprotective Effect of Alpha7 Nicotinic Acetylcholine Receptor on Ischemic Stroke. 3-MA, alpha7nAChR, OGD/R
2021 Baicalin-loaded macrophage-derived exosomes ameliorate ischemic brain injury via the antioxidative pathway. BA, pMCAO, ROS
2021 Bioinformatic Analysis of Exosomal MicroRNAs of Cerebrospinal Fluid in Ischemic Stroke Rats After Physical Exercise. CSF, GO, KEGG, miRNAs, SD
2021 BK Channel-Mediated Microglial Phagocytosis Alleviates Neurological Deficit After Ischemic Stroke. DMSO, OGD
10  2021 Bone Marrow-Derived IL-1Ra Increases TNF Levels Poststroke. BM, CXCL1, IL, IL-1ra, TLR2, TNF
11  2021 Brain Protein Expression Profile Confirms the Protective Effect of the ACTH(4-7)PGP Peptide (Semax) in a Rat Model of Cerebral Ischemia-Reperfusion. ---
12  2021 Continuous Glibenclamide Prevents Hemorrhagic Transformation in a Rodent Model of Severe Ischemia-Reperfusion. EVT, HT
13  2021 CQMUH-011 Inhibits LPS-Induced Microglia Activation and Ameliorates Brain Ischemic Injury in Mice. ERK, I/R, IkappaBalpha, IL, LPS, MAPKs, MyD88, PCNA, TLR4, TNF
14  2021 Cryptotanshinone reduces neurotoxicity induced by cerebral ischemia-reperfusion injury involving modulation of microglial polarization. CTS, I/R
15  2021 Delayed diapedesis of CD8 T cells contributes to long-term pathology after ischemic stroke in male mice. ---
16  2021 Dental pulp stem cell-derived exosomes alleviate cerebral ischaemia-reperfusion injury through suppressing inflammatory response. DPSC-Exos, I/R, OGD/R
17  2021 Different combinations of high-frequency rTMS and cognitive training improve the cognitive function of cerebral ischemic rats. DEGs, PSCI, rTMS, rTMS-COG
18  2021 Dynamic changes in Beclin-1, LC3B and p62 at various time points in mice with temporary middle cerebral artery occlusion and reperfusion (tMCAO). TEM
19  2021 Elastase inhibitor agaphelin protects from acute ischemic stroke in mice by reducing thrombosis, blood-brain barrier damage, and inflammation. ---
20  2021 Extracellular vesicles derived from M2 microglia reduce ischemic brain injury through microRNA-135a-5p/TXNIP/NLRP3 axis. CCK-8, ELISA, EVs, miR-135a-5p, NLRP3, OGD/R, RT-qPCR, TTC, TXNIP
21  2021 Fatty Acid-Binding Proteins Aggravate Cerebral Ischemia-Reperfusion Injury in Mice. FABPs
22  2021 Genistein-3'-sodium sulfonate Attenuates Neuroinflammation in Stroke Rats by Down-Regulating Microglial M1 Polarization through α7nAChR-NF-κB Signaling Pathway. GSS, LPS
23  2021 Geranylgeranylacetone ameliorated ischemia/reperfusion induced-blood brain barrier breakdown through HSP70-dependent anti-apoptosis effect. BBB, EB, GGA, HSP, I/R, OGD, qRT-PCR, TEER, TJPs
24  2021 Glycocalyx is critical for blood-brain barrier integrity by suppressing caveolin1-dependent endothelial transcytosis following ischemic stroke. BBB, Cav-1, GCX
25  2021 Harnessing the mitochondrial integrity for neuroprotection: Therapeutic role of piperine against experimental ischemic stroke. BDNF, CREB, cyt c, GFAP, IL-1beta, IS, PIP, qRT-PCR
26  2021 High-salt diet downregulates TREM2 expression and blunts efferocytosis of macrophages after acute ischemic stroke. AIS, HSD, TREM2
27  2021 Impact of hydroxytyrosol on stroke: tracking therapy response on neuroinflammation and cerebrovascular parameters using PET-MR imaging and on functional outcomes. EVOO, HT, NO, TBARS
28  2021 Increased Renal Dysfunction, Apoptosis, and Fibrogenesis Through Sympathetic Hyperactivity After Focal Cerebral Infarction. ACIS, AKI
29  2021 Interference with long noncoding RNA SNHG3 alleviates cerebral ischemia-reperfusion injury by inhibiting microglial activation. HDAC3, OGD/R
30  2021 Ischemic Stroke Increased Gadolinium Deposition in the Brain and Aggravated Astrocyte Injury After Gadolinium-Based Contrast Agent Administration: Linear Versus Macrocyclic Agents. Gd, MMP, OGD/R, ROS
31  2021 Long-term dietary supplementation with plant-derived omega-3 fatty acid improves outcome in experimental ischemic stroke. ALA
32  2021 MCT2 overexpression promotes recovery of cognitive function by increasing mitochondrial biogenesis in a rat model of stroke. MCT2
33  2021 Medioresinol as a novel PGC-1α activator prevents pyroptosis of endothelial cells in ischemic stroke through PPARα-GOT1 axis. BBB, BMVECs, MDN, mtROS, OGD
34  2021 Metformin prevents stroke damage in non-diabetic female mice with chronic kidney disease. AMPK, CKD
35  2021 Microglia exosomal miRNA-137 attenuates ischemic brain injury through targeting Notch1. OGD
36  2021 MicroRNA-376b-5p targets SOX7 to alleviate ischemic brain injury in a mouse model through activating Wnt/β-catenin signaling pathway. Hb, miR, SOX7
37  2021 Model-free leakage index estimation of the blood-brain barrier using dual dynamic susceptibility contrast MRI acquisition. BBB, DSC
38  2021 Mucosal-Associated Invariant T Cells Are Involved in Acute Ischemic Stroke by Regulating Neuroinflammation. MAIT
39  2021 Natural Killer Cells Are Present in Rag1-/- Mice and Promote Tissue Damage During the Acute Phase of Ischemic Stroke. NK, WT
40  2021 Neonatal stroke enhances interaction of microglia-derived extracellular vesicles with microglial cells. EVs, MEV, nSMase2
41  2021 Neuroprotective effects of four different fluids on cerebral ischaemia/reperfusion injury in rats through stabilization of the blood-brain barrier. BBB, CI/RI, HTS, MN, NS, SD
42  2021 Neuroprotective effects of Scallop-derived plasmalogen in a mouse model of ischemic stroke. NVU, sPlas
43  2021 Neutrophil extracellular traps contribute to tissue plasminogen activator resistance in acute ischemic stroke. AIS, APC, ECs, NETs, PAI-1, PCA, PLTs, PS, tPA, vWF
44  2021 Normalisation of glucose metabolism by exendin-4 in the chronic phase after stroke promotes functional recovery in male diabetic mice. GLP-1, T2D
45  2021 OTULIN is a new target of EA treatment in the alleviation of brain injury and glial cell activation via suppression of the NF-κB signalling pathway in acute ischaemic stroke rats. EA, IL-1beta, IL-6, NF-kappaB, OTULIN, SD, TNF-alpha
46  2021 Paeoniflorin improves functional recovery through repressing neuroinflammation and facilitating neurogenesis in rat stroke model. ---
47  2021 Phthalide derivative CD21 attenuates tissue plasminogen activator-induced hemorrhagic transformation in ischemic stroke by enhancing macrophage scavenger receptor 1-mediated DAMP (peroxiredoxin 1) clearance. DAMP, HT, NF-kappaB, Prx1, TLR4, tPA, WT
48  2021 Platelet endothelial cell adhesion molecule-1 is a gatekeeper of neutrophil transendothelial migration in ischemic stroke. PECAM-1
49  2021 Preferential Targeting Cerebral Ischemic Lesions with Cancer Cell-Inspired Nanovehicle for Ischemic Stroke Treatment. BBB
50  2021 Protective effects of Dimethyl malonate on neuroinflammation and blood-brain barrier after ischemic stroke. BBB, DMM
51  2021 Pseudoginsenoside-F11 promotes functional recovery after transient cerebral ischemia by regulating the microglia/macrophage polarization in rats. JMJD3, PF11
52  2021 Quercetin attenuates ischemia reperfusion injury by protecting the blood-brain barrier through Sirt1 in MCAO rats. BBB
53  2021 Receptor for Advanced Glycation End Products Is Involved in LPA5-Mediated Brain Damage after a Transient Ischemic Stroke. LPA5, RAGE
54  2021 Repurposing FDA Approved Drugs as JNK3 Inhibitor for Prevention of Neuroinflammation Induced by MCAO in Rats. JNK
55  2021 RNA-Seq analysis of knocking out the neuroprotective proton-sensitive GPR68 on basal and acute ischemia-induced transcriptome changes and signaling in mouse brain. GO, LTP, WT
56  2021 Sigma-1 Receptor Agonist TS-157 Improves Motor Functional Recovery by Promoting Neurite Outgrowth and pERK in Rats with Focal Cerebral Ischemia. ---
57  2021 Supplemental N-3 Polyunsaturated Fatty Acids Limit A1-Specific Astrocyte Polarization via Attenuating Mitochondrial Dysfunction in Ischemic Stroke in Mice. n-3 PUFAs
58  2021 The hypoxia sensitive metal transcription factor MTF-1 activates NCX1 brain promoter and participates in remote postconditioning neuroprotection in stroke. FAO, MRE, MTF-1, NCX1, RLIP
59  2021 The Key Regulator of Necroptosis, RIP1 Kinase, Contributes to the Formation of Astrogliosis and Glial Scar in Ischemic Stroke. RIP1K, VEGF-D
60  2021 The Mitochondrial mitoNEET Ligand NL-1 Is Protective in a Murine Model of Transient Cerebral Ischemic Stroke. ---
61  2021 The selective alpha7 nicotinic acetylcholine receptor agonist AR-R17779 does not affect ischemia-reperfusion brain injury in mice. alpha7nAChR, ddPCR
62  2021 Thymus quinquecostatus Celak. ameliorates cerebral ischemia-reperfusion injury via dual antioxidant actions: Activating Keap1/Nrf2/HO-1 signaling pathway and directly scavenging ROS. CIRI, HO-1, HPE, Nrf2, OS, PRF, ROS
63  2021 Time-dependent progression of hemorrhagic transformation after transient ischemia and its association with GPR68-dependent protection. HT, WT
64  2021 TNF-α antagonism rescues the effect of ageing on stroke: Perspectives for targeting inflamm-ageing. old
65  2021 Upregulated Long Non-coding RNA ALMS1-IT1 Promotes Neuroinflammation by Activating NF-κB Signaling in Ischemic Cerebral Injury. HBM, mNSS, OGD
66  2021 Verapamil as an Adjunct Therapy to Reduce tPA Toxicity in Hyperglycemic Stroke: Implication of TXNIP/NLRP3 Inflammasome. BBB, HMGB-1, I/R, MMP-9, NF-kappaB, NLRP3, tPA, TXNIP
67  2021 β2 glycoprotein I participates in phagocytosis of apoptotic neurons and in vascular injury in experimental brain stroke. aPL, beta2GPI, ihBMEC
68  2020 A novel compound DBZ ameliorates neuroinflammation in LPS-stimulated microglia and ischemic stroke rats: Role of Akt(Ser473)/GSK3β(Ser9)-mediated Nrf2 activation. ---
69  2020 A Polyphenolic Complex Attenuates Inflammatory Response and Blood- Brain Barrier Disruption. BBB, i.p, Iba1, MCP-1, TNF-alpha
70  2020 A preclinical randomized controlled study of ischemia treated with Ginkgo biloba extracts: Are complex components beneficial for treating acute stroke? GBEs, pdMCAO, PRCT
71  2020 A sphingosine kinase 2-mimicking TAT-peptide protects neurons against ischemia-reperfusion injury by activating BNIP3-mediated mitophagy. SPK2
72  2020 Ability of Post-treatment Glycyrrhizic Acid to Mitigate Cerebral Ischemia/Reperfusion Injury in Diabetic Mice. GA, I/R, IF
73  2020 Adiponectin peptide alleviates oxidative stress and NLRP3 inflammasome activation after cerebral ischemia-reperfusion injury by regulating AMPK/GSK-3β. APN, APNp, I/R, OGD-R
74  2020 Antioxidant nanomedicine with cytoplasmic distribution in neuronal cells shows superior neurovascular protection properties. BBB, ROS
75  2020 Antioxidative effects of a novel dietary supplement Neumentix in a mouse stroke model. RA
76  2020 B cells migrate into remote brain areas and support neurogenesis and functional recovery after focal stroke in mice. STPT, WT
77  2020 BMS-986020, a Specific LPA1 Antagonist, Provides Neuroprotection against Ischemic Stroke in Mice. BMS, LPA1
78  2020 Bone Marrow Stromal Cell Transplantation Drives Molecular Switch from Autophagy to the Ubiquitin-Proteasome System in Ischemic Stroke Mice. BMSC, UPS
79  2020 Celecoxib-Dependent Neuroprotection in a Rat Model of Transient Middle Cerebral Artery Occlusion (tMCAO) Involves Modifications in Unfolded Protein Response (UPR) and Proteasome. ER, GRP78, IRE1, PERK, UPR, UPS
80  2020 Cepharanthine attenuates cerebral ischemia/reperfusion injury by reducing NLRP3 inflammasome-induced inflammation and oxidative stress via inhibiting 12/15-LOX signaling. ALOX15, CEP, I/R, NLRP3, OGD/R
81  2020 Characterization of the inflammatory post-ischemic tissue by full volumetric analysis of a multimodal imaging dataset. MMPs, MRI, PET, TSPO, VOI
82  2020 CircRNA_0001449 disturbs phosphatidylinositol homeostasis and AKT activity by enhancing Osbpl5 translation in transient cerebral ischemia. ER, PIs, PM, PS
83  2020 Cofilin Inhibition by Limk1 Reduces Rod Formation and Cell Apoptosis after Ischemic Stroke. ATP-D, MAP2, NeuN, TTC, TUNEL
84  2020 Compound AD110 Acts as Therapeutic Management for Alzheimer's Disease and Stroke in Mouse and Rat Models. AD, IL-10, LPS
85  2020 Donepezil attenuates injury following ischaemic stroke by stimulation of neurogenesis, angiogenesis, and inhibition of inflammation and apoptosis. BDNF, i.p, PGC-1alpha
86  2020 Early Reperfusion Following Ischemic Stroke Provides Beneficial Effects, Even After Lethal Ischemia with Mature Neural Cell Death. CNS, pMCAO
87  2020 Effect of fluoxetine on HIF-1α- Netrin/VEGF cascade, angiogenesis and neuroprotection in a rat model of transient middle cerebral artery occlusion. ---
88  2020 Effects of RO27-3225 on neurogenesis, PDGFRβ+ cells and neuroinflammation after cerebral infarction. SVZ
89  2020 Effects of Thymoquinone on Small-Molecule Metabolites in a Rat Model of Cerebral Ischemia Reperfusion Injury Assessed using MALDI-MSI. MALDI-MSI
90  2020 Estrogen and progesterone attenuate glutamate neurotoxicity via regulation of EAAT3 and GLT-1 in a rat model of ischemic stroke. EAATs
91  2020 Exosomes Derived From CircAkap7-Modified Adipose-Derived Mesenchymal Stem Cells Protect Against Cerebral Ischemic Injury. ADSCs, exo-circAkap7, OGD-R
92  2020 Farnesoid X receptor knockout protects brain against ischemic injury through reducing neuronal apoptosis in mice. FXR, KO
93  2020 Fingolimod Inhibits Inflammation but Exacerbates Brain Edema in the Acute Phases of Cerebral Ischemia in Diabetic Mice. BBB
94  2020 FKBP5 Exacerbates Impairments in Cerebral Ischemic Stroke by Inducing Autophagy via the AKT/FOXO3 Pathway. AIS, FKBP5, I/R, OGD/R
95  2020 Gene Expression Dynamics at the Neurovascular Unit During Early Regeneration After Cerebral Ischemia/Reperfusion Injury in Mice. BBB
96  2020 Gonadal Hormones E2 and P Mitigate Cerebral Ischemia-Induced Upregulation of the AIM2 and NLRC4 Inflammasomes in Rats. AIS, OGD
97  2020 HDAC3 inhibition ameliorates ischemia/reperfusion-induced brain injury by regulating the microglial cGAS-STING pathway. cGAS, cGAS-STING, ELISA, HDAC3, I/R, PCR
98  2020 HIF‑1alpha attenuates neuronal apoptosis by upregulating EPO expression following cerebral ischemia‑reperfusion injury in a rat MCAO model. EMP9, EPO
99  2020 High-Density Lipoprotein Therapy in Stroke: Evaluation of Endothelial SR-BI-Dependent Neuroprotective Effects. BBB, HDLs, OGD
100  2020 High-Frequency rTMS Improves Cognitive Function by Regulating Synaptic Plasticity in Cerebral Ischemic Rats. DEGs, GO, KEGG, mNSS, MWM, PPI, PSCI, rTMS