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Abbreviation : TfR
Long Form : transferrin receptor
No. Year Title Co-occurring Abbreviation
1984 Target structure for natural killer cells: evidence against a unique role for transferrin receptor. NK
1984 The structural gene for transferrin (TF) maps to 3q21----3qter. A2HS, Cp, Tf
1985 A rapid and efficient microtechnique for the analysis of functional transferrin receptors on tumor cells. ---
1985 Intracellular movement of cell surface receptors after endocytosis: resialylation of asialo-transferrin receptor in human erythroleukemia cells. ---
1985 Modulation of transferrin receptor expression by inhibitors of nucleic acid synthesis. DFOA
1985 Segregation of the NK-sensitive phenotype in human x mouse somatic cell hybrids reveals separate genetic control of recognition and postrecognition determinants. NK, NKr, NKS
1985 Single-cell analysis of the relationship among transferrin receptors, proliferation, and cell cycle phase in K562 cells. ---
1985 Transferrin receptor bearing cells in the peripheral blood of patients with rheumatoid arthritis. NK, RA
1985 Transit of receptors for epidermal growth factor and transferrin through clathrin-coated pits. Analysis of the kinetics of receptor entry. EGF-R
10  1986 A transferrin receptor antibody represents one signal for the induction of IL 2 production by a human T cell line. IL-2, PHA, PMA
11  1986 Delineation and characterization of human B cell subpopulations at various stages of activation by using a B cell-specific monoclonal antibody. PHA-sup
12  1986 Growth fraction of tumour cells and infiltration density with natural killer-like (HNK1+) cells in non-Hodgkin lymphomas. NHL, NK
13  1986 Human natural killer cell lysis of virus-infected cells. Relationship to expression of the transferrin receptor. NK
14  1986 Immunostaining of transferrin and transferrin receptor in human seminiferous tubules. Tf
15  1986 Membrane traffic in animal cells: cellular glycoproteins return to the site of Golgi mannosidase I. ---
16  1986 Phorbol diesters and transferrin modulate lymphoblastoid cell transferrin receptor expression by two different mechanisms. ---
17  1986 Phorbol ester-induced surface transferrin receptor modulation. No correlation with decreased cell proliferation. DAG, TPA
18  1986 Sequential expression of protooncogenes during lectin-stimulated mitogenesis of normal human lymphocytes. IL-2R, PBMC, PHA
19  1986 Transferrin receptor is inversely correlated with estrogen receptor in breast cancer. ER, PgR
20  1986 Transferrin receptors and natural killer cell lysis. A study using Colo 205 cells exposed to 60 Hz electromagnetic fields. NK
21  1986 Transferrin receptors on tumor and bone marrow cells: lack of involvement as target structure for natural killer cells. mAbs, NK
22  1986 Transferrin receptors recycle to cis and middle as well as trans Golgi cisternae in Ig-secreting myeloma cells. anti-TFR
23  1986 [Interrelation between transferrin receptor expression and intracellular ferritin concentration in leukemia cells and normal marrow cells]. FER
24  1987 A c-myc antisense oligodeoxynucleotide inhibits entry into S phase but not progress from G0 to G1. IL-2R
25  1987 Altered expression of beta-globin, transferrin receptor, and ornithine decarboxylase in Friend murine erythroleukemia cells inhibited by alpha-difluoromethylornithine. DFMO, ODC
26  1987 Disparity between expression of transferrin receptor ligand binding and non-ligand binding domains on human lymphocytes. L-PHA, PBL, PMA
27  1987 Heterogeneity of the human transferrin receptor and use of anti-transferrin receptor antibodies to detect tumours in vivo. ---
28  1987 Immunotoxins to the murine transferrin receptor: intracavitary therapy of mice bearing syngeneic peritoneal tumors. rRTA
29  1987 Increased expression of the B lymphocyte receptor for transferrin is stimulated by in vivo crosslinking of cell surface IgD. ---
30  1987 Natural killer cells in peripheral blood and the mixed lymphocyte response: interaction with the transferrin receptor. MLR, NK
31  1987 Regulation of lymphokine production and human T lymphocyte activation by 1,25-dihydroxyvitamin D3. Specific inhibition at the level of messenger RNA. IL-2, mRNA
32  1987 Transferrin receptor expression by human bladder transitional cell carcinomas. ---
33  1987 Transferrin receptor expression in normal skin and in various cutaneous tumors. ---
34  1987 Transferrin receptor expression in the leukaemias and lymphoproliferative disorders. APAAP
35  1987 [Expression of a cross-reactive antigen on the surface of human epidermoid carcinomas overproducing EGF-receptor shared with RSV-induced tumors]. CDC, EGFR, ELISA, MoAb, RSV, TASA
36  1988 A cellular deficiency in the rheumatoid one-way mixed lymphocyte reaction. ---
37  1988 A model for the structure and functions of iron-responsive elements. IRE, UTR
38  1988 A pH-dependent reversible conformational transition of the human transferrin receptor leads to self-association. ---
39  1988 Binding properties of monoclonal antibody to the cytoplasmic domain of transferrin receptor. Tf
40  1988 Cisplatin-induced erythroid differentiation in K562 cells: modulation of transferrin receptor. ---
41  1988 Comparison of phorbol ester/calcium ionophore and phytohemagglutinin-induced signaling in human T lymphocytes. Demonstration of interleukin 2-independent transferrin receptor gene expression. IL-2, PDB
42  1988 Differential expression of c-myc and the transferrin receptor in G1 synchronized M1 myeloid leukemia cells. ---
43  1988 Experimental studies on the treatment of hepatocellular carcinoma with cis-platin.transferrin complex. cis-platin, PKC
44  1988 Expression of membrane activation antigens on murine B lymphocytes stimulated with lipopolysaccharide. LPS
45  1988 Identification of transferrin receptor in cervical and endometrial tissues. ---
46  1988 Increase in surface expression of transferrin receptors on cultured hepatocytes of adult rats in response to iron deficiency. ---
47  1988 Iron-responsive elements: regulatory RNA sequences that control mRNA levels and translation. IRE, mRNA
48  1988 Membrane transferrin receptor (TfR) and nuclear proliferation-associated Ki-67 expression in hemopoietic malignancies. TfRs
49  1988 Quantification of rat hepatocyte transferrin receptors with poly- and monoclonal antibodies and protein A. ---
50  1988 The pathways of endocytosed transferrin and secretory protein are connected in the trans-Golgi reticulum. AT
51  1988 Trace metals, surface receptors and growth of human normal and leukemic lymphocytes. IL-2R, Me, Me, Me, TU
52  1988 Transferrin receptor and 4F2 expression by NK-sensitive and NK-resistant tumour cell lines. NK, TPA
53  1988 Transferrin receptor expression of AML blasts is related to their proliferative potential. AML, FACS
54  1989 A cytosolic protein binds to structural elements within the iron regulatory region of the transferrin receptor mRNA. IRE, UTR
55  1989 An epitope of the transferrin receptor is exposed on the cell surface of high-grade but not low-grade human lymphomas. FSC, IgG2a, IL
56  1989 Antitumor activity in mice of an immunotoxin made with anti-transferrin receptor and a recombinant form of Pseudomonas exotoxin. ---
57  1989 Chromosomal localization of nucleic acid-binding proteins by affinity mapping: assignment of the IRE-binding protein gene to human chromosome 9. IREs
58  1989 Concentration of transferrin receptor in human placental coated vesicles. ---
59  1989 Expression of epidermal growth factor receptor and transferrin receptor by human trophoblast populations. EGF, EGFR
60  1989 In situ localization of melanotransferrin (melanoma-associated antigen P97) in human liver. A light- and electronmicroscopic immunohistochemical study. Tf
61  1989 Neonatal hemochromatosis. The regulation of transferrin-receptor and ferritin synthesis by iron in cultured fibroblastic-line cells. AH, NH
62  1989 Prostaglandins from human T suppressor/cytotoxic cells modulate natural killer antibacterial activity. ---
63  1989 Receptor-mediated transport of heme by hemopexin regulates gene expression in mammalian cells. Hepa, HO, HPX
64  1989 Relations between the intracellular pathways of the receptors for transferrin, asialoglycoprotein, and mannose 6-phosphate in human hepatoma cells. ASGPR, DAB, MPR
65  1989 Selective suppressive effects of Trypanosoma cruzi on activated human lymphocytes. IL-2R
66  1989 T lymphocyte activation antigens in Guillain-Barre syndrome and chronic idiopathic demyelinating polyradiculoneuropathy. CIDP, GBS, HLA, IL-2R
67  1989 The inhibitory effect of human interferon alpha on the generation of lymphokine-activated killer activity. IL-2, LAK, NK, PBMC
68  1989 The role of T cell phenotypes in decreased lymphoproliferation of the elderly. IL-2R
69  1989 Transcriptional regulation of transferrin receptor expression by cultured lymphoblastoid T cells treated with phorbol diesters. ---
70  1989 Transferrin receptor expression in normal, iron-deficient and iron-overloaded rats. ---
71  1989 Transferrin receptor synthesis is an early event in B cell activation. ---
72  1989 Transferrin receptors and cation-independent mannose-6-phosphate receptors deliver their ligands to two distinct subpopulations of multivesicular endosomes. M6PR, Tf, Tf-Au
73  1989 Transforming growth factors beta slow down cell-cycle progression in a murine interleukin-2 dependent T-cell line. IL-2, IL-2R, pTGF-beta 1 and 2, TGF-beta
74  1990 1,25-Dihydroxyvitamin D3 modulates the effects of interleukin 2 independent of IL-2 receptor binding. IFN-gamma
75  1990 A common mechanism may be involved in the selective loss of plasma membrane functions during reticulocyte maturation. ---
76  1990 Activation antigens in patients with Sjogren's syndrome. IL-2, MC, PB, SS
77  1990 An immunohistochemical assessment of cellular proliferation markers in head and neck squamous cell cancers. EGFR, SCCs
78  1990 Avian inflammatory macrophage function: shifts in arachidonic acid metabolism, respiratory burst, and cell-surface phenotype during the response to Sephadex. i.p, PECs
79  1990 Coordinate post-transcriptional regulation of ferritin and transferrin receptor expression: the role of regulated RNA-protein interaction. 5'UTR, IRE-BP, IREs
80  1990 Defective expression of IL-2 receptors on peripheral blood lymphocytes from patients with cluster headache. CH, IL-2, mAb, PBL
81  1990 Effect of erythroid differentiation factor on erythroid differentiation and proliferation of K-562 cells. EDF
82  1990 Elevated transferrin receptor content in human prostate cancer cell lines assessed in vitro and in vivo. BPH
83  1990 Epidermal growth factor and transferrin receptor expression in human embryonic and fetal epidermal cells. EGFR
84  1990 Growth factor-dependent regulation of transferrin receptor in proliferating and quiescent macrophages. BMM, CSF-1
85  1990 Head injury: an immunologic deficit in T-cell activation. IL-2R
86  1990 Induction of T cell activation by monoclonal antibodies specific for the transferrin receptor. IL, mAb
87  1990 Intracellular interactions of transferrin and its receptor during biosynthesis. Tf, TGR
88  1990 Isolation of fetal DNA from nucleated erythrocytes in maternal blood. bp
89  1990 Neonatal hemochromatosis. Genetic analysis of transferrin-receptor, H-apoferritin, and L-apoferritin loci and of the human leukocyte antigen class I region. HH, HLA, NH
90  1990 Phenotypic analysis of a large number of normal human bone marrow sample by flow cytometry. Ld BMC
91  1990 Relationships between the cell cycle and the expression of c-myc and transferrin receptor genes during induced myeloid differentiation. ---
92  1990 Release of hydrogen peroxide and expression of HLA-DR and transferrin receptors by monocytes and peritoneal macrophages from patients undergoing continuous ambulatory peritoneal dialysis and normal controls. CAPD
93  1990 Response of rat mammary gland transferrin receptors to maternal dietary iron during pregnancy and lactation. ---
94  1990 Selective immunosuppression of prodigiosin 25-C and FK506 in the murine immune system. Con A, CTL, IL-2, IL-2R, PHA, SRBC, TD, TI
95  1990 Selective suppression of lymphokine production by human hybridoma suppressor factor (HSF). HSF
96  1990 Structural requirements of iron-responsive elements for binding of the protein involved in both transferrin receptor and ferritin mRNA post-transcriptional regulation. IRE-BP, IREs
97  1990 The biosynthetic pathway of MHC class II but not class I molecules intersects the endocytic route. ---
98  1990 The transferrin receptor system is not involved in the pathogenesis of hematological disorders with 3q inversion. RAEB
99  1990 Transferrin receptor in normal and neoplastic brain tissue: implications for brain-tumor immunotherapy. GBM's
100  1990 Transferrin receptors in injured brain. ---
101  1990 Two mechanisms of transferrin receptor induction by anti-Ig in B cells. IgG
102  1990 Ultrastructural localization and internalization of proteoglycan epitopes in a human non-Hodgkin (B) lymphoma. HS, PG, PG
103  1990 Up-regulation of transferrin receptor gene expression by granulocyte colony-stimulating factor in human myeloid leukemia cells. G-CSF, Tf
104  1991 Blunted erythropoietin production and decreased erythropoiesis in early pregnancy. EPO
105  1991 Differential regulation of iron regulatory element-binding protein(s) in cell extracts of activated lymphocytes versus monocytes-macrophages. IRE-BP, PHA
106  1991 Expression of transferrin receptors by monocytes and peritoneal macrophages from renal failure patients treated by continuous ambulatory peritoneal dialysis (CAPD). CAPD
107  1991 Immune dysfunction in mice with plasmacytomas. I. Evidence that transforming growth factor-beta contributes to the altered expression of activation receptors on host B lymphocytes. PC-mice, sIgM, TGF-beta1
108  1991 Intracellular heme coordinately modulates globin chain synthesis, transferrin receptor number, and ferritin content in differentiating Friend erythroleukemia cells. FLC, Hb, SA
109  1991 Intracellular localization of newly synthesized transferrin receptors in the peripheral sheep reticulocyte. ---
110  1991 Non-sequence-specific inhibition of transferrin receptor expression in HL-60 leukemia cells by phosphorothioate oligodeoxynucleotides. ---
111  1991 Proliferative responses of B cells from elderly humans: abnormalities in early responsiveness are related to alterations in B cell activation molecules. SAC, SpA
112  1991 Resistance of myeloid leukaemia cell lines to ricin A-chain immunotoxins. ---
113  1991 Selective loss of pertussis toxin-sensitive G-proteins from the plasma membrane after antibody-induced internalization of T-cell surface molecules. CTX, PTX, TCR
114  1991 Specific binding sites for H-ferritin on human lymphocytes: modulation during cellular proliferation and potential implication in cell growth control. IL-2, PHA
115  1991 The ontogeny of transferrin receptors in the embryonic chick retina: an immunohistochemical study. ---
116  1991 The role of the transferrin receptor for the activation of human lymphocytes. PBMC, Tf
117  1991 Transferrin receptor activity as a marker in transitional cell carcinoma of the bladder. ---
118  1991 Transferrin receptors and selective iron deposition in pancreatic B cells of iron-overloaded rats. Ft, Tf
119  1991 Translation and the stability of mRNAs encoding the transferrin receptor and c-fos. ---
120  1991 [An improved purification of human placental transferrin receptor and biochemical properties of the receptor]. ---
121  1991 [Expression and extracellular release of transferrin receptors on erythropoiesis]. EPO, IRE, Tf
122  1992 Activation of protein kinase C accelerates internalization of transferrin receptor but not of major histocompatibility complex class I, independent of their phosphorylation status. IEF, MHC, PKC
123  1992 An iron-sulfur cluster plays a novel regulatory role in the iron-responsive element binding protein. IRE-BP, IREs
124  1992 Assessment of neonatal avian inflammatory macrophage function following embryonic cyclophosphamide exposure. CP, fMLP, i.p, PECs
125  1992 Characterization of early and late endocytic compartments of the transferrin cycle. Transferrin receptor antibody blocks erythroid differentiation by trapping the receptor in the early endosome. AEV, PLC
126  1992 Characterization of the defect in a variant of HL-60 promyelocytic leukemia cells with reduced transferrin receptor expression. Tf-Gel
127  1992 Coordination of cellular iron metabolism by post-transcriptional gene regulation. eALAS, IRE, IRE-BP, UTRs
128  1992 Detection of fetal cells with 47,XY,+21 karyotype in maternal peripheral blood. ---
129  1992 Effects of tautomycin, a protein phosphatase inhibitor, on recycling of mammalian cell surface molecules. PDBu
130  1992 Erythropoiesis in multiple myeloma: defective red cell production due to inappropriate erythropoietin production. EPO
131  1992 Evaluation of erythroid marrow response to recombinant human erythropoietin in patients with cancer anaemia. rHuEPO
132  1992 Expression of the proliferation-associated Ki-67 antigen of transferrin receptors and of DNA polymerase alpha in human tumour lines: implications for in vitro chemoresistance. ---
133  1992 Inhibition of heme synthesis decreases transferrin receptor expression in mouse erythroleukemia cells. DFO, HMBA, MEL, SA
134  1992 Internalization efficiency of the transferrin receptor. ---
135  1992 Nonopsonic uptake of Mycobacterium avium complex by human monocytes and alveolar macrophages. AMs, FcR, MAC, PBMs
136  1992 Presence of O-linked oligosaccharide on a threonine residue in the human transferrin receptor. sTfR
137  1992 Recycling of transferrin receptors and heparan sulfate proteoglycans in a rat parathyroid cell line. HS
138  1992 Regulation of transferrin receptors by iron in human erythroblasts. ---
139  1992 Regulation of transferrin, transferrin receptor, and ferritin genes in human duodenum. mRNAs, Tf
140  1992 Relationship between gallium 67 citrate scanning and transferrin receptor expression in lung diseases. 67Ga, 67Ga scan, IPF
141  1992 Role of vesicular traffic in the transport of surface transferrin receptor to the Golgi complex in cultured human cells. ---
142  1992 Soluble factors levels in the initial staging of high-grade non-Hodgkin's lymphomas. B2M, ESR, IL-2, IL-2R, IL-6, IL-8, NHL
143  1992 Studies on the susceptibility to NK-mediated lysis and the simultaneous expression of various surface molecules in anthracyclin-treated K562 cells and in four K562 cell clones. EA, GPA
144  1992 The hamster transferrin receptor contains Ser/Thr-linked oligosaccharides: use of a lectin-resistant CHO cell line to identify glycoproteins containing these linkages. CHO, HPA
145  1992 Therapeutic effect of ansamitocin targeted to tumor by a bispecific monoclonal antibody. mAb
146  1992 Transferrin receptor mediates uptake and presentation of hepatitis B envelope antigen by T lymphocytes. HBenvAg, HBV
147  1992 Transforming growth factor-beta inhibits human T-cell proliferation through multiple targets. TGF-beta
148  1992 Two mechanisms of iron uptake from transferrin by melanoma cells. The effect of desferrioxamine and ferric ammonium citrate. DFO, FAC, Tf
149  1992 [Changes in T cell subsets and the expression of receptors of transferrin and interleukin-2 in chronic active hepatitis]. ACH, CSH
150  1992 [Human mammary carcinoma. A model for the relationship between tumor proliferation, tumor-associate macrophages, and prognostic factors]. mAb, MPS, TAL, TAM
151  1992 [Immunohistochemical study of transferrin receptor expression in hepatocellular carcinoma]. HCC
152  1992 [Preparation of human placenta microvillous membrane and the study of its transferrin receptor]. PMM
153  1992 [Study of the infiltrating lymphocyte subsets and transferrin receptor in gastric and colorectal carcinomas]. MNC
154  1992 [Study on cell proliferation of oral malignant tumor with transferrin receptor]. ---
155  1993 Antigen entry into early endosomes is insufficient for MHC class II processing. Tf
156  1993 Dynamics of erythropoietic recovery following bone marrow transplantation: role of marrow proliferative capacity and erythropoietin production in autologous versus allogeneic transplants. ---
157  1993 Early prediction of response to recombinant human erythropoietin in patients with the anemia of renal failure by serum transferrin receptor and fibrinogen. Hct, rHuEPO
158  1993 Expression and loss of the transferrin receptor in growing and differentiating HD3 cells. ---
159  1993 Expression of endothelial cell activation antigens in microvessels from patients with multiple sclerosis. Ags, ICAM-1, uPAR, VCAM-1
160  1993 Ferrochelatase, glutathione peroxidase and transferrin receptor mRNA synthesis and levels in mouse erythroleukemia cells. Fe-PIH, GSH-Px, HMBA, INH, PA, PIH, SA
161  1993 Interleukin-2-dependent transcriptional and post-transcriptional regulation of transferrin receptor mRNA. IL-2, IRF
162  1993 Iron regulatory factor expressed from recombinant baculovirus: conversion between the RNA-binding apoprotein and Fe-S cluster containing aconitase. IRE, IRF, UTR
163  1993 Macropinosome maturation and fusion with tubular lysosomes in macrophages. CI-MPR, lgp-A, rM-CSF
164  1993 Modulation of transferrin receptor mRNA by transferrin-gallium in human myeloid HL60 and lymphoid CCRF-CEM leukaemic cells. Tf, Tf-Ga
165  1993 Origin of a soluble truncated transferrin receptor. ---
166  1993 Quantitative assessment of erythropoiesis and functional classification of anemia based on measurements of serum transferrin receptor and erythropoietin. EPO, ETU, Hct, RBC, RCM
167  1993 Role of microtubules in transferrin receptor transport from the cell surface to endosomes and the Golgi complex. ---
168  1993 Serum transferrin receptor for assessment of iron status in healthy prepubertal and early pubertal boys. ---
169  1993 Subcutaneous recombinant human erythropoietin for the treatment of anemia in myelodysplastic syndromes. EPO, MDS, rhEPO
170  1993 The clinical significance of serum transferrin receptor levels in sickle cell disease. SC
171  1993 The in vitro response of human tumour cells to desferrioxamine is growth medium dependent. FBS
172  1993 The IRE (iron regulatory element) family: structures which regulate mRNA translation or stability. eALAS, FL, IRE, IREs
173  1993 The transferrin receptor. IRE, IRE-BP
174  1993 Tumor necrosis factor alpha cooperates with interleukin 3 in the recruitment of a primitive subset of human CD34+ progenitors. HPC, IL-3, TNF-alpha
175  1994 Antigen targeting to antigen-presenting cells enhances presentation to class II-restricted T lymphocytes. HBenvAg, HIV, mAb
176  1994 Antisense oligodeoxynucleotides for IL-2, c-myc and transferrin receptor synchronize mitogen-activated lymphocytes in the G1 phase. IL-2
177  1994 Cell membrane fluidity in K562 cells and its relation to receptor expression. CMF, IFN-gamma
178  1994 Early rise in serum concentration of transferrin receptor induced by recombinant human erythropoietin in very-low-birth-weight infants. rHuEPO
179  1994 Elimination of the O-linked glycosylation site at Thr 104 results in the generation of a soluble human-transferrin receptor. ---
180  1994 Estimation of effective and total erythropoiesis in myelodysplasia using serum transferrin receptor and erythropoietin concentrations, with automated reticulocyte parameters. EPO, MCH, MCV, MDS
181  1994 Evidence that the pathway of transferrin receptor mRNA degradation involves an endonucleolytic cleavage within the 3' UTR and does not involve poly(A) tail shortening. ---
182  1994 Fetal hemoglobin and potassium in isolated transferrin receptor-positive dense sickle reticulocytes. RBCs
183  1994 Generation of the soluble transferrin receptor requires cycling through an endosomal compartment. CHO
184  1994 Induced redistribution of cell surface receptors by alternating current electric fields. LDLR
185  1994 Iron-deficiency anemia is associated with high concentrations of transferrin receptor in serum. ---
186  1994 Is serum transferrin receptor useful for detecting iron-deficiency in anaemic patients with chronic inflammatory diseases? ---
187  1994 Molecular regulation of iron proteins. eALAS
188  1994 Nef 27, but not the Nef 25 isoform of human immunodeficiency virus-type 1 pNL4.3 down-regulates surface CD4 and IL-2R expression in peripheral blood mononuclear cells and transformed T cells. PHA
189  1994 Psychoimmune investigation in obsessive-compulsive disorder: assays of plasma transferrin, IL-2 and IL-6 receptor, and IL-1 beta and IL-6 concentrations. IL, OCD, sIL-6R
190  1994 Regulation of transferrin receptor mRNA expression. Distinct regulatory features in erythroid cells. IRE, IRE-BP, MEL
191  1994 Rev of human immunodeficiency virus and Rex of the human T-cell leukemia virus type I can counteract an mRNA downregulatory element of the transferrin receptor mRNA. HIV-1, HTLV-I
192  1994 Serum transferrin receptor and erythropoiesis in children with newly diagnosed acute lymphoblastic leukemia. ---
193  1994 Soluble transferrin mediates targeting of hepatitis B envelope antigen to transferrin receptor and its presentation by activated T cells. HBenvAg, HBV
194  1994 T lymphocytes infiltrating renal cell carcinoma have a reduced expression of transferrin receptor. RCC, RT-PCR
195  1994 The establishment of polarity and enhanced transcytosis of transferrin receptors in enterocyte-like Caco-2 cells. BFA, HRP, TEER
196  1994 Transferrin receptor gene expression during rat liver regeneration. Evidence for post-transcriptional regulation by iron regulatory factorB, a second iron-responsive element-binding protein. IRE, IRFB
197  1994 Transferrin receptor in oral tumors. ---
198  1994 Transforming growth factor beta 1 inhibits cytokine-induced CNS endothelial cell activation. Ags
199  1994 Up-regulation of c-myc induces the gene expression of the murine homologues of p34cdc2 and cyclin-dependent kinase-2 in T lymphocytes. CDK
200  1994 [A study of relationship between proliferative activity and expressed transferrin receptor content in cancer cells]. ---
201  1994 [An analysis of the iron related proteins during erythroid differentiation in K562 cells]. IRE, IRE-BP, UTR
202  1994 [Characterization of cell lines from metastatic maxillary cancer]. EGFR, LAK
203  1995 A tyrosine-containing motif mediates ER retention of CD3-epsilon and adopts a helix-turn structure. ER
204  1995 Characterization of the intracellular GLUT-4 compartment. MPR
205  1995 Distinct association of transferrin receptor with HLA class I molecules on HUT-102B and JY cells. FCET
206  1995 Effect of transcription inhibitors on the iron-dependent degradation of transferrin receptor mRNA. IRP
207  1995 Effects of protein kinase modulators on transferrin receptor expression in human leukaemic HL-60 cells. dbcAMP, PKA, PKC, PMA
208  1995 Effects of Viscum album L. on cyclophosphamide-treated peripheral blood mononuclear cells in vitro: sister chromatid exchanges and activation/proliferation marker expression. CP, PBMC
209  1995 Expression of a constitutive mutant of iron regulatory protein 1 abolishes iron homeostasis in mammalian cells. IREs, IRPs
210  1995 Flow cytometric reticulocyte maturity index: a useful laboratory parameter of erythropoietic activity in anemia. EPO, RMI
211  1995 Hsp-70 is closely associated with the transferrin receptor in exosomes from maturing reticulocytes. ---
212  1995 IFN-beta selectively down-regulates transferrin receptor expression in human peripheral blood macrophages by a post-translational mechanism. Tf
213  1995 Increased plasma concentrations of interleukin-6, soluble interleukin-6, soluble interleukin-2 and transferrin receptor in major depression. IL, sIL-6R
214  1995 Interleukin-2 and interleukin-6 in schizophrenia and mania: effects of neuroleptics and mood stabilizers. CMI, IL-6, sIL-6R
215  1995 Iron availability is transiently improved by intravenous iron medication in patients on chronic hemodialysis. CRP, IL-1b, rHuEPO, TNF-alpha
216  1995 Iron-responsive element-binding protein mRNA levels during erythroid differentiation of murine erythroleukemia cells. HMBA, IRE-BP I, MEL
217  1995 LPS inhibits the intracellular growth of Legionella pneumophila in thioglycolate elicited murine peritoneal macrophages by iron-dependent, tryptophan-independent, oxygen-independent, and arginine-independent mechanisms. LPS, RNI, ROI, Trp
218  1995 Nitric-oxide-mediated activation of iron-regulatory protein controls hepatic iron metabolism during acute inflammation. IRP, NO
219  1995 Oligomerized transferrin receptors are selectively retained by a lumenal sorting signal in a long-lived endocytic recycling compartment. Tf
220  1995 Plasma-soluble interleukin-2 and transferrin receptor in schizophrenia and major depression. IL-1beta, sIL-2R
221  1995 Quantitative assessment of erythropoiesis in haemodialysis patients demonstrates gradual expansion of erythroblasts during constant treatment with recombinant human erythropoietin. rHuEPO
222  1995 Rapid responses to oxidative stress mediated by iron regulatory protein. IREs, IRP, ROIs
223  1995 Selective reentry of recycling cell surface glycoproteins to the biosynthetic pathway in human hepatocarcinoma HepG2 cells. dMM, DPP-IV, TGN
224  1995 Sister chromatid exchange-inducing DNA lesions and depression of activation markers on the surface of cultured peripheral blood mononuclear cells after the addition of streptococcal pyrogenic exotoxins A and C. IL-2R alpha chain, PBMC, SCE, SPE, WBCC
225  1995 The critical glycosylation site of human transferrin receptor contains a high-mannose oligosaccharide. endo H, HPAE-PAD, RP-HPLC
226  1995 The determination of plasma transferrin receptor (TfR) in patients with heart valve prosthesis: a useful evaluation of bone-marrow response to traumatic haemolysis. ---
227  1995 The effect of redox-related species of nitrogen monoxide on transferrin and iron uptake and cellular proliferation of erythroleukemia (K562) cells. IRE-BP, IREs, NO, SNAP, SNP
228  1995 Transferrin receptor distribution and iron deposition in the hepatic lobule of iron-overloaded rats. Ft, iron, Tf
229  1995 Transferrin receptor induces tyrosine phosphorylation in T cells and is physically associated with the TCR zeta-chain. ---
230  1995 Transport from late endosomes to lysosomes, but not sorting of integral membrane proteins in endosomes, depends on the vacuolar proton pump. MPR, Tf
231  1995 [Transferrin receptor and iron deposition pattern in the hepatic lobules of the iron-deficient and iron-overloaded rats]. Tf
232  1996 A single-chain bispecific Fv2 molecule produced in mammalian cells redirects lysis by activated CTL. Ab, Abs, sFv
233  1996 Binding characteristics and antitumor properties of 1A10 bispecific antibody recognizing gp40 and human transferrin receptor. mAb
234  1996 Characterisation of bovine transferrin receptor on normal activated and Theileria parva-transformed lymphocytes by a new monoclonal antibody. Con A, mAb, PWM, Tf
235  1996 Circulating transferrin receptor during erythropoietin medication of anemic patients with rheumatoid arthritis. RA, rHuEPO
236  1996 Cleavage of the transferrin receptor by human granulocytes: differential proteolysis of the exosome-bound TFR. ---
237  1996 Cleavage of the transferrin receptor is influenced by the composition of the O-linked carbohydrate at position 104. ---
238  1996 Compartment ablation analysis of the insulin-responsive glucose transporter (GLUT4) in 3T3-L1 adipocytes. Tf-HRP
239  1996 Day-to-day variation of transferrin receptor and ferritin in healthy men and women. CV
240  1996 Differential regulation of IRP1 and IRP2 by nitric oxide in rat hepatoma cells. IREs, LPS, NO, SNAP, UTRs
241  1996 Effect of modulation of the transferrin receptor on gallium-67 uptake and cytotoxicity in lymphoma cell lines. ara-C
242  1996 Expression of genes involved in iron metabolism in mouse intestine. ---
243  1996 Indicators of immune activation in major depression. AGP, CRP, IL-6, sIL-2R, sIL-6R
244  1996 Multivesicular endosomes containing internalized EGF-EGF receptor complexes mature and then fuse directly with lysosomes. EGFR, LAMP1, M6PR, MVB
245  1996 Nitric oxide alters the expression of gamma-globin, H-ferritin, and transferrin receptor in human K562 cells at the posttranscriptional level. NO
246  1996 Regulation of transferrin receptor synthesis by human cytotrophoblast cells in culture. DFO, FAC
247  1996 Soluble transferrin receptor-transferrin complex in serum: measurement by latex agglutination nephelometric immunoassay. LA, Tf, TRC
248  1996 The determination of plasma transferrin receptor as good index of erythropoietic activity in renal anemia and after renal transplantation. CRF, EPO, RDT
249  1996 The glucose transporter (GLUT-4) and vesicle-associated membrane protein-2 (VAMP-2) are segregated from recycling endosomes in insulin-sensitive cells. VAMP, VAMP-2
250  1996 Transcellular delivery of an insulin-transferrin conjugate in enterocyte-like Caco-2 cells. BFA, Tf
251  1996 Transcriptional regulation of transferrin receptor expression during phorbol-ester-induced HL-60 cell differentiation. Evidence for a negative regulatory role of the phorbol-ester-responsive element-like sequence. PMA, TRE
252  1996 Transcytosis of protein through the mammalian cerebral epithelium and endothelium. III. Receptor-mediated transcytosis through the blood-brain barrier of blood-borne transferrin and antibody against the transferrin receptor. BBB
253  1996 Transferrin dependence of Ga (NO3)3 inhibition of growth in human-derived small cell lung cancer cells. SCLC, Tf
254  1996 [Analysis of the iron-related proteins during proliferation and differentiational change of human hepatoblastoma cells (HepG2)]. IRE, IRE-BP, UTR
255  1997 Anemia associated with advanced prostatic adenocarcinoma: effects of recombinant human erythropoietin. Hb, rHuEPO
256  1997 Characterization of the Chlamydia trachomatis vacuole and its interaction with the host endocytic pathway in HeLa cells. CI-M6PR, FITC, hpi, TGN
257  1997 Components of biological variation in serum soluble transferrin receptor: relationships to serum iron, transferrin and ferritin concentrations, and immune and haematological variables. Hb, Ht, MCH, MCV, RDW, sIL-2R, Tf
258  1997 Erythroblastic inclusions in dominantly inherited beta thalassemias. ---
259  1997 Expression of transferrin receptors in endothelial cells transfected by electroporation. EC, HRP
260  1997 Flow cytometric evaluation of transferrin receptor in transitional cell carcinoma. FCM, TCC
261  1997 High doses of recombinant human erythropoietin fail to accelerate platelet reconstitution in allogeneic bone marrow transplantation. Results of a pilot study. BMT, PLT, RBC, rhEPO
262  1997 Identification and characterization of two distinct intracellular GLUT4 pools in rat skeletal muscle: evidence for an endosomal and an insulin-sensitive GLUT4 compartment. ---
263  1997 In vivo immunomodulatory effects of clozapine in schizophrenia. IL-1Ra, IL-6, sIL-2
264  1997 Increased N-glycosylation and reduced transferrin-binding capacity of transferrin receptor isolated from placentae of diabetic women. PNG-F
265  1997 Iron regulatory protein 1 is not required for the modulation of ferritin and transferrin receptor expression by iron in a murine pro-B lymphocyte cell line. IREs, IRPs
266  1997 Isolation of the transferrin receptor from human placenta. ---
267  1997 Markers of masked iron deficiency and effectiveness of EPO therapy in chronic renal failure. ---
268  1997 Modulation of doxorubicin resistance in a doxorubicin-resistant human leukaemia cell by an immunoliposome targeting transferring receptor. DOX
269  1997 Non-transferrin-bound iron induced by myeloablative chemotherapy. NTBI
270  1997 Nuclear domains in skeletal myotubes: the localization of transferrin receptor mRNA is independent of its half-life and restricted by binding to ribosomes. RER
271  1997 Overexpression of manganese superoxide dismutase gene changes the metastasis associated-character of the mouse fibrosarcoma, FSa-II. FSa-II, MnSOD
272  1997 Overproduction of fungal ribotoxin alpha-sarcin in Escherichia coli: generation of an active immunotoxin. OmpA
273  1997 Pathways for the regulation of macrophage iron metabolism by the anti-inflammatory cytokines IL-4 and IL-13. IRP1, NO
274  1997 Percentile estimates for transferrin receptor in normal infants 9-15 mo of age. ---
275  1997 Saturation of the endocytic pathway for the transferrin receptor does not affect the endocytosis of the epidermal growth factor receptor. ---
276  1997 Selection of highly metastatic rat MTLn2 mammary adenocarcinoma cell variants using in vitro growth response to transferrin. ---
277  1997 Serum transferrin receptor and its ratio to serum ferritin in the diagnosis of iron deficiency. ACD, IDA
278  1997 Soluble and cell-associated transferrin receptor in lung cancer. BAL, COPD, ELISA, NSE, sTfR
279  1997 Structure of human transferrin receptor oligosaccharides: conservation of site-specific processing. ---
280  1997 Transferrin receptor recycling in rat hepatocytes is regulated by protein phosphatase 2A, possibly through effects on microtubule-dependent transport. MCYST, NOC, OKA, PP, PP2A, Tf
281  1997 [Effects of iron deficiency on expression of transferrin receptor in human lymphocytes]. ---
282  1997 [Preliminary study on the inhibition of hepatitis B viral expression in vitro via specific receptors mediated ribozyme transfer]. ASGPR
283  1998 Analysis of GLUT4 distribution in whole skeletal muscle fibers: identification of distinct storage compartments that are recruited by insulin and muscle contractions. ---
284  1998 Control of hemoglobin synthesis in erythroid differentiating K562 cells. II. Studies of iron mobilization in erythroid cells by high-performance liquid chromatography-electrochemical detection. ALA, ALAS, Hb, HPLC-ED
285  1998 Crystal structure of the hemochromatosis protein HFE and characterization of its interaction with transferrin receptor. ---
286  1998 Decay-accelerating factor (CD55) and membrane inhibitor of reactive lysis (CD59) are released within exosomes during In vitro maturation of reticulocytes. AChE, DAF, GPI, LFA-3, MIRL, PNH
287  1998 Diagnostic utility of serum transferrin receptors measurement in assessing iron status. ---
288  1998 Disparity of serum transferrin receptor measurements among different assay methods. ---
289  1998 Distinct saturable pathways for the endocytosis of different tyrosine motifs. ---
290  1998 Effect of androgen therapy and anemia on serum erythropoietin levels in patients with aplastic anemia and myelodysplastic syndromes. AA, ARC, EPO, MDS
291  1998 Effect of reactive oxygen species on iron regulatory protein activity. IRE, IRPs, ROS
292  1998 Evaluation of the potential of transferrin-adriamycin conjugates in the treatment of bladder cancer. CHO, Tf-ADR
293  1998 GLUT4 and transferrin receptor are differentially sorted along the endocytic pathway in CHO cells. GSVs
294  1998 Immunohistochemical localization of the murine transferrin receptor (TfR) on blood-tissue barriers using a novel anti-TfR monoclonal antibody. BBB, mAb
295  1998 Increased intracellular sequestration of the insulin-regulated aminopeptidase upon differentiation of 3T3-L1 cells. IRAP
296  1998 Iron status in pregnant women: which measurements are valid? MCV, TIBC, ZPP
297  1998 Lack of coordinate control of ferritin and transferrin receptor expression during rat liver regeneration. IRE
298  1998 Meat intake and iron status in late infancy: an intervention study. Hb, HMG, LMG, SF
299  1998 Molecular genetics and control of iron metabolism in hemochromatosis. beta2m, C282Y, HC
300  1998 Naturally processed peptides from HLA-DQ7 (alpha1*0501-beta1*0301): influence of both alpha and beta chain polymorphism in the HLA-DQ peptide binding specificity. ---
301  1998 New DNA polymorphisms define ethnically distinct haplotypes in the human transferrin receptor gene. ---
302  1998 Oxidative stress leads to a rapid alteration of transferrin receptor intravesicular trafficking. LDLR
303  1998 Plasma transferrin receptor levels and indices of erythropoiesis and iron status in healthy term infants. EPO, Hb, TIBC
304  1998 Regulation of transferrin function and expression: review and update. ---
305  1998 Structural model of phospholipid-reconstituted human transferrin receptor derived by electron microscopy. ---
306  1998 The hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand binding. beta2m, C282Y
307  1998 The neural cell adhesion molecule L1 interacts with the AP-2 adaptor and is endocytosed via the clathrin-mediated pathway. CAMs
308  1998 The transferrin receptor cytoplasmic domain determines its rate of transport through the biosynthetic pathway and its susceptibility to cleavage early in the pathway. ---
309  1998 Transferrin and transferrin receptor gene expression and iron uptake in hepatocellular carcinoma in the rat. HCC, mRNA
310  1998 Transferrin and transferrin receptor in human hypophysis and pituitary adenomas. Tf
311  1998 Transferrin receptor assay and zinc protoporphyrin as markers of iron-deficient erythropoiesis in end-stage renal disease patients. ESRD, TS, ZPP
312  1998 Transferrin receptor functions as a signal-transduction molecule for its own recycling via increases in the internal Ca2+ concentration. ---
313  1998 Transferrin receptor in T cell activation and transplantation. CTL, IFN-gamma, IL-2, mAb, MLR
314  1998 Transferrin receptor mutation analysis in hereditary hemochromatosis patients. HH
315  1998 [Gene delivery into human cancer cells via transferrin receptor]. ---
316  1999 Association of HFE protein with transferrin receptor in crypt enterocytes of human duodenum. HH
317  1999 Beta 2-adrenergic receptor endocytic pathway is controlled by a saturable mechanism distinct from that of transferrin receptor. beta2AR
318  1999 Characterization of insulin-responsive GLUT4 storage vesicles isolated from 3T3-L1 adipocytes. Tf, TGN
319  1999 Characterization of the translation-dependent step during iron-regulated decay of transferrin receptor mRNA. IRPs, TK
320  1999 Control of transferrin receptor expression via nitric oxide-mediated modulation of iron-regulatory protein 2. IREs, NO, SNP
321  1999 Coxiella burnetii infection increases transferrin receptors on J774A. 1 cells. ---
322  1999 Crystal structure of the ectodomain of human transferrin receptor. Tf
323  1999 Differential effects of transferrin receptor blockade on the cellular mechanisms involved in graft rejection. IL, mAb, MHC, TCR
324  1999 Enhanced allograft survival via simultaneous blockade of transferrin receptor and interleukin-2 receptor. IL-2R, mAbs, Th
325  1999 Evaluation of an ELISA test for determination of the serum transferrin receptor. Demonstration of discordance between results obtained with two methods. ---
326  1999 Evaluation of iron status of Finnish blood donors using serum transferrin receptor. ---
327  1999 HIF-1-mediated activation of transferrin receptor gene transcription by iron chelation. DFO, HRE
328  1999 Higher concentrations of serum transferrin receptor in children than in adults. ---
329  1999 Increased placental iron regulatory protein-1 expression in diabetic pregnancies complicated by fetal iron deficiency. IREs
330  1999 Insulin regulation of protein traffic in rat adipose cells. GLUT-4, MPR
331  1999 Interaction between haemochromatosis and transferrin receptor genes in different neoplastic disorders. TF
332  1999 Iron-regulatory proteins, iron-responsive elements and ferritin mRNA translation. IREs, IRPs
333  1999 Mechanism involved in gallium-67 (Ga-67) uptake by human lymphoid cell lines. Ga-67, MoAb
334  1999 Mechanism of increased iron absorption in murine model of hereditary hemochromatosis: increased duodenal expression of the iron transporter DMT1. HH, IRE
335  1999 Molecular cloning of transferrin receptor 2. A new member of the transferrin receptor-like family. Tf
336  1999 Platelet activating factor receptor (PAF-R) is found in a large endosomal compartment in human umbilical vein endothelial cells. ER, HUVECs, PAFR, TH-R
337  1999 Post-transcriptional control via iron-responsive elements: the impact of aberrations in hereditary disease. IREs, IRPs, UTRs
338  1999 Regulation of iron metabolism in murine J774 macrophages: role of nitric oxide-dependent and -independent pathways following activation with gamma interferon and lipopolysaccharide. IFN-gamma, IRE, LPS, NMMA, NO, Tf
339  1999 Soluble transferrin receptor as a potential determinant of iron loading in congenital anaemias due to ineffective erythropoiesis. CDA II, XLSA
340  1999 Structure, function and clinical significance of transferrin receptors. sTfR
341  1999 The effect of intracellular iron concentration and nitrogen monoxide on Nramp2 expression and non-transferrin-bound iron uptake. DFO, FAC, IRE, IRPs, RT-PCR, SNAP, Tf, UTR
342  1999 The extracellular regions of PSMA and the transferrin receptor contain an aminopeptidase domain: implications for drug design. AMP, CPG2, PSMA, SGAP
343  1999 The hemochromatosis protein HFE competes with transferrin for binding to the transferrin receptor. Fe-Tf, MHC
344  1999 The hereditary hemochromatosis protein, HFE, specifically regulates transferrin-mediated iron uptake in HeLa cells. Tf
345  1999 The impact of malarial infection and diet on the anaemia status of rural pregnant Malawian women. ID, IDRC, OMNI
346  1999 The serum transferrin receptor concentration in seven fetuses with hemolytic disease. ---
347  1999 The transferrin receptor binding site on HFE, the class I MHC-related protein mutated in hereditary hemochromatosis. MHC
348  1999 Transferrin receptor induction by hypoxia. HIF-1-mediated transcriptional activation and cell-specific post-transcriptional regulation. ---
349  1999 Transferrin receptor is negatively modulated by the hemochromatosis protein HFE: implications for cellular iron homeostasis. ---
350  2000 Anemia and deficiencies of folate and vitamin B-6 are common and vary with season in Chinese women of childbearing age. Hb
351  2000 Characterization of MHC class II-presented peptides generated from an antigen targeted to different endocytic compartments. LAMP1, OVA
352  2000 Cholera toxin is found in detergent-insoluble rafts/domains at the cell surface of hippocampal neurons but is internalized via a raft-independent mechanism. CT
353  2000 Comparison of the interactions of transferrin receptor and transferrin receptor 2 with transferrin and the hereditary hemochromatosis protein HFE. Tf
354  2000 Crystal structure of the hereditary haemochromatosis protein HFE complexed with transferrin receptor. MHC
355  2000 Effects of interferon-gamma and lipopolysaccharide on macrophage iron metabolism are mediated by nitric oxide-induced degradation of iron regulatory protein 2. IFN-gamma, LPS
356  2000 Gene expression of divalent metal transporter 1 and transferrin receptor in duodenum of Belgrade rats. ---
357  2000 Identification and localization of divalent metal transporter-1 (DMT-1) in term human placenta. DMT1
358  2000 Identification of an erythroid active element in the transferrin receptor gene. ---
359  2000 Impact of acute malaria on plasma concentrations of transferrin receptors. ACT, AGP, CRP
360  2000 Inclusion of a furin-sensitive spacer enhances the cytotoxicity of ribotoxin restrictocin containing recombinant single-chain immunotoxins. scFv
361  2000 Interaction between haemochromatosis and transferrin receptor genes in hepatocellular carcinoma. HCC, HH
362  2000 Interferon-gamma and lipopolysaccharide regulate the expression of Nramp2 and increase the uptake of iron from low relative molecular mass complexes by macrophages. IFN-gamma, IRP, LPS, Nramp2, Tf
363  2000 Interleukin 15 mediates epithelial changes in celiac disease. IFN, IL, TNF
364  2000 Iron, ferritin, transferrin, and transferrin receptor in the adult rat retina. EM, IS, ISH, OS, PIXE, RPE, RT-PCR, Tf
365  2000 Iron-overload and genotypic expression of HFE mutations H63D/C282Y and transferrin receptor Hin6I and BanI polymorphism in german patients with hereditary haemochromatosis. HH
366  2000 Limited synergistic effect of antisense oligonucleotides against bcr-abl and transferrin receptor mRNA in leukemic cells in culture. ASOs, CML
367  2000 Malaria, hookworms and recent fever are related to anemia and iron status indicators in 0- to 5-y old Zanzibari children and these relationships change with age. EP, SF
368  2000 Mechanisms of differential transferrin receptor expression in normal hematopoiesis. EPO, HPCs, IRP, IRP1, IRP2
369  2000 Modulation of transferrin synthesis, transferrin receptor expression, iNOS expression and NO production in mouse macrophages by cytokines, either alone or in combination. iNOS, Tf
370  2000 Oligodendroglial cell differentiation in rat brain is accelerated by the intracranial injection of apotransferrin. OLGc
371  2000 Postpartum iron status in nonlactating participants and nonparticipants in the special supplemental nutrition program for women, infants, and children. Hb, WIC
372  2000 Rab11 regulates the compartmentalization of early endosomes required for efficient transport from early endosomes to the trans-golgi network. Cb, Rab11wt, STxB, TGN
373  2000 Serum transferrin receptor in children and adolescents with inflammatory bowel disease. ACD, IBD, IDA, MCV
374  2000 Site-specific expression of transferrin receptor by human colon cancer cells directly correlates with eradication by antitransferrin recombinant immunotoxin. PE
375  2000 The mouse SKD1, a homologue of yeast Vps4p, is required for normal endosomal trafficking and morphology in mammalian cells. ---
376  2000 The nutritional assessment of iron status. ACD, IDA, IDE
377  2000 The role of selective transport in neuronal protein sorting. ---
378  2000 The role of the membrane-bound tumour antigen, melanotransferrin (p97), in iron uptake by the human malignant melanoma cell. DFO, FAC, MTf, PtdIns-PLC, Tf
379  2000 The structure and function of HFE. HH, MHC
380  2000 Transferrin receptor 2: continued expression in mouse liver in the face of iron overload and in hereditary hemochromatosis. HH
381  2000 Transferrin receptor activity and localisation in the rat duodenum. ---
382  2000 Transferrin-bound and transferrin free iron uptake by cultured rat astrocytes. Fe II
383  2000 Transport and function of syntaxin 3 in human epithelial intestinal cells. SI, Syn
384  2000 Tyrosine phosphorylation of Eps15 is required for ligand-regulated, but not constitutive, endocytosis. EGFR
385  2000 Usefulness of serum transferrin receptor and serum ferritin in diagnosis of iron deficiency in infancy. ---
386  2000 Variations in dietary iron alter brain iron metabolism in developing rats. ID, PND, SU, Tf
387  2001 Binding to the transferrin receptor is required for endocytosis of HFE and regulation of iron homeostasis. LDLR
388  2001 Characteristics of the interaction between Hsc70 and the transferrin receptor in exosomes released during reticulocyte maturation. Hsc70
389  2001 Characterization and intracellular trafficking pattern of vacuoles containing Chlamydia pneumoniae in human epithelial cells. AO, BafA1, CI-M6PR, Cpn, LyT, TR
390  2001 Characterization of the iron transporter DMT1 (NRAMP2/DCT1) in red blood cells of normal and anemic mk/mk mice. DMT1, EPO, PHZ
391  2001 Differential cytotoxicity of Mn(II) and Mn(III): special reference to mitochondrial [Fe-S] containing enzymes. Mn, mtDNA
392  2001 Discriminating between iron deficiency anemia and anemia of chronic disease using traditional indices of iron status vs transferrin receptor concentration. ACD, IDA, MCV, RDW, SIC, TIBC
393  2001 Disturbance of cellular iron uptake and utilisation by aluminium. Al
394  2001 Duodenal expression of a putative stimulator of Fe transport and transferrin receptor in anemia and hemochromatosis. SFT
395  2001 Effect of intravenous iron supplementation on erythropoiesis in erythropoietin-treated premature infants. EPO, Hb, Hct, IPC, MDA, rHuEPO, VLBW
396  2001 Endothelial cell activation following moderate traumatic brain injury. EC, ICAM-1, MHC, PI, TBI
397  2001 Human cytomegalovirus protein US2 interferes with the expression of human HFE, a nonclassical class I major histocompatibility complex molecule that regulates iron homeostasis. HCMV, hHFE, MHC
398  2001 Iron overload following manganese exposure in cultured neuronal, but not neuroglial cells. Mn
399  2001 Iron transport in a lymphoid cell line with the hemochromatosis C282Y mutation. Tf
400  2001 Iron-fortified and unfortified cow's milk: effects on iron intakes and iron status in young children. CI
401  2001 Is Parkinson's disease the heterozygote form of Wilson's disease: PD = 1/2 WD? IBP-1, PD, WD
402  2001 MHC class II presentation of endogenously expressed antigens by transfected dendritic cells. DC, OVA, PEI
403  2001 Modulation of cellular iron metabolism by hydrogen peroxide. Effects of H2O2 on the expression and function of iron-responsive element-containing mRNAs in B6 fibroblasts. IREs, IRP
404  2001 Molecular aspects of iron absorption and HFE expression. ---
405  2001 Phage derived peptides for targeting of doxorubicin conjugates to solid tumours. SPR
406  2001 Pumping iron: the strange partnership of the hemochromatosis protein, a class I MHC homolog, with the transferrin receptor. HH, MHC
407  2001 Randomized intervention study comparing several regimens for the treatment of moderate anemia among refugee children in Kigoma Region, Tanzania. SP, VAC
408  2001 Regulation of vascular endothelial growth factor transcription by endothelial PAS domain protein 1 (EPAS1) and possible involvement of EPAS1 in the angiogenesis of renal cell carcinoma. EPAS1, HIF-1alpha, RCC, RT-PCR, VEGF
409  2001 Reticulocyte transferrin receptor (TfR) expression and contribution to soluble TfR levels. EPO, sTfR
410  2001 Sorting and directed transport of membrane proteins during development of hippocampal neurons in culture. ---
411  2001 Structural and functional stability of the mature transferrin receptor from human placenta. ---
412  2001 The effects of iron deficiency on lymphocyte cytokine production and activation: preservation of hepatic iron but not at all cost. LRA
413  2001 Tyrphostin-8 enhances transferrin receptor-mediated transcytosis in Caco-2- cells and inreases hypoglycemic effect of orally administered insulin-transferrin conjugate in diabetic rats. BFA, GI, In-HSA, In-Tf, STZ, TEER
414  2001 Variable phenotypic presentation of iron overload in H63D homozygotes: are genetic modifiers the cause? HH, IO
415  2001 [Expression of transferrin receptor and ferrochelatase mRNAs in MEL cells]. McAb
416  2001 [The relationship between the expression of transferrin receptors (TfR) on leukemia cells and the cell proliferation and iron metabolism status in childhood acute leukemias]. ---
417  2002 A single viral protein HCMV US2 affects antigen presentation and intracellular iron homeostasis by degradation of classical HLA class I and HFE molecules. beta2m, CTL, HCMV, MHC
418  2002 Association of human transferrin receptor with GABARAP. ---
419  2002 Developmental changes in the expression of iron regulatory proteins and iron transport proteins in the perinatal rat brain. DMT1, IRPs, PND
420  2002 Effect of different durations of exercise on transferrin-bound iron uptake by rat erythroblast. ---
421  2002 Erythroblast iron metabolism in sideroblastic and sideropenic states. ACD, IDA, IREs, IRPs, sTfR
422  2002 Erythroid differentiation and protoporphyrin IX down-regulate frataxin expression in Friend cells: characterization of frataxin expression compared to molecules involved in iron metabolism and hemoglobinization. DMSO, FA, mRNA
423  2002 Establishment and characterization of an immortalized Z310 choroidal epithelial cell line from murine choroid plexus. BCB, TTR
424  2002 Expected value of serum soluble transferrin receptor, erythropoietin and ferritin and their correlation among healthy non-anemic Thai children. EPO
425  2002 Fractionation analysis of the endosomal compartment during rat reticulocyte maturation. 3-MA
426  2002 Fully automated proteomic detection of cervical dysplasia. EGFR, HPV, HSIL
427  2002 Heterotypic interactions between transferrin receptor and transferrin receptor 2. Tf, TfR2
428  2002 Imaging gene expression in the brain in vivo in a transgenic mouse model of Huntington's disease with an antisense radiopharmaceutical and drug-targeting technology. HD, mAb, PNA
429  2002 Impaired retinal iron homeostasis associated with defective phagocytosis in Royal College of Surgeons rats. ELISA, EM, ISH, OS, PIXE, PN, RCS, RPE, RT-PCR, Tf
430  2002 Iodination significantly influences the binding of human transferrin to the transferrin receptor. ---
431  2002 Iron deficiency can upregulate expression of transferrin receptor at both the mRNA and protein level. DFO, IREs, IRPs, TfR2, UTR
432  2002 Isolation and characterization of the two major intracellular Glut4 storage compartments. IRAP
433  2002 Molecular mechanisms involved in the actions of apotransferrin upon the central nervous system: Role of the cytoskeleton and of second messengers. aTf, Ca-CaMK, cAMP, CNPase, CREB, MBP, OLGc, PLP
434  2002 Mutational analysis of the transferrin receptor reveals overlapping HFE and transferrin binding sites. Tf
435  2002 Processing of the human transferrin receptor at distinct positions within the stalk region by neutrophil elastase and cathepsin G. ---
436  2002 Proteomic analysis and molecular characterization of tissue ferritin light chain in hepatocellular carcinoma. HCC, MALDI-MS, mRNA, PCR, T-FLC
437  2002 Role of Ets-1 in transcriptional regulation of transferrin receptor and erythroid differentiation. FLC
438  2002 Sex differences in iron status during infancy. Hb, MCV, ZPP
439  2002 Shedding of the transferrin receptor is mediated constitutively by an integral membrane metalloprotease sensitive to tumor necrosis factor alpha protease inhibitor-2. sTfR, TAPI-2
440  2002 Systemic tumor-targeted gene delivery by anti-transferrin receptor scFv-immunoliposomes. scFv
441  2002 Targeting cancer cells with transferrin conjugates containing the non-toxic type 2 ribosome-inactivating proteins nigrin b or ebulin l. RIPs
442  2002 The Advia 120 red blood cells and reticulocyte indices are useful in diagnosis of iron-deficiency anemia. RBC
443  2002 The diagnostic criteria for iron deficiency in infants should be reevaluated. Hb, ID, IDA, MCV, ZPP
444  2002 The epithelial-specific adaptor AP1B mediates post-endocytic recycling to the basolateral membrane. LDLR, TGN
445  2002 The exosome pathway in K562 cells is regulated by Rab11. MVBs
446  2002 The expression level determines the surface distribution of the transferrin receptor in Trypanosoma brucei. GPI
447  2002 The physiological significance of transferrin receptor variations in Trypanosoma brucei. ESAG, VSG
448  2002 Transferrin receptor gene expression and transferrin-bound iron uptake are increased during postischemic rat liver reperfusion. I/R, IRP, mRNA
449  2002 Transferrin receptor hyperexpression in primary erythroblasts is lost on transformation by avian erythroblastosis virus. IRP1, mRNA, SCF
450  2002 Transferrin receptor-dependent iron uptake is responsible for doxorubicin-mediated apoptosis in endothelial cells: role of oxidant-induced iron signaling in apoptosis. DOX, ROS
451  2002 Transferrin toxin but not transferrin receptor immunotoxin is influenced by free transferrin and iron saturation. Tf
452  2002 Up-regulation of transferrin receptor expression in hepatocytes by habitual alcohol drinking is implicated in hepatic iron overload in alcoholic liver disease. ALD
453  2002 Whole blood collected on filter paper provides a minimally invasive method for assessing human transferrin receptor level. ---
454  2002 Widespread expression of an exogenous gene in the eye after intravenous administration. GFAP, mAb, PIL, SV
455  2002 [Effects of the chemokine MIP-1alpha on anemia and inflammation in rheumatoid arthritis]. EPO, MIP-1alpha, RA, SAA
456  2003 1-Methyl-4-phenylpyridinium (MPP+)-induced apoptosis and mitochondrial oxidant generation: role of transferrin-receptor-dependent iron and hydrogen peroxide. CGNs, FeTBAP, ROS, TUNEL
457  2003 A neutralizing monoclonal antibody (mAb A24) directed against the transferrin receptor induces apoptosis of tumor T lymphocytes from ATL patients. ATL, HTLV-1, IL-2Ralpha
458  2003 A novel method for monitoring surface membrane trafficking on hippocampal acute slice preparation. GluR A
459  2003 Absence of toxicity of chronic weekly intravenous gene therapy with pegylated immunoliposomes. mAb, PIL, TH
460  2003 Alterations in cellular IRP-dependent iron regulation by in vitro manganese exposure in undifferentiated PC12 cells. IRPs, Mn
461  2003 CD81 engineered with endocytotic signals mediates HCV cell entry: implications for receptor usage by HCV in vivo. LDLR
462  2003 Combinations of two capsid regions controlling canine host range determine canine transferrin receptor binding by canine and feline parvoviruses. CPV, FPV
463  2003 Cytokine-mediated regulation of iron transport in human monocytic cells. IFN-gamma, IL-10, LPS, NTBI
464  2003 Effects of iron regulatory protein regulation on iron homeostasis during hypoxia. DMT1, Ft, IREs, mAco, UTR
465  2003 Evidence for the interaction of the hereditary haemochromatosis protein, HFE, with the transferrin receptor in endocytic compartments. LAMP1, Tf
466  2003 Expression of the hemochromatosis (HFE) gene modulates the cellular uptake of 67Ga. fHFE, Tf
467  2003 Extra-renal erythropoietin secretion after bilateral nephrectomy. ---
468  2003 Gene expression of transferrin and transferrin receptor in brains of control vs. iron-deficient rats. Tf
469  2003 Growth factor receptor expression varies among high-grade gliomas and normal brain: epidermal growth factor receptor has excellent properties for interstitial fusion protein therapy. EGFR, IL-13R, IL-4R
470  2003 Immunohistochemical study of transferrin receptor expression in the placenta of pre-eclamptic pregnancy. hCG
471  2003 In vivo knockdown of gene expression in brain cancer with intravenous RNAi in adult rats. mAb, PILs, RNAi, shRNA
472  2003 Intracellular Ca(2+) regulates the cellular iron uptake in K562 cells. PKC, PMA, Tf, TG
473  2003 Intracellular transport of a heterologous membrane protein, the human transferrin receptor, in Saccharomyces cerevisiae. ER, PM
474  2003 Intravenous nonviral gene therapy causes normalization of striatal tyrosine hydroxylase and reversal of motor impairment in experimental parkinsonism. BBB, mAb, PIL, TH
475  2003 Iron deficiency alters iron regulatory protein and iron transport protein expression in the perinatal rat brain. DMT1, ID
476  2003 Mechanisms of HFE-induced regulation of iron homeostasis: Insights from the W81A HFE mutation. Tf
477  2003 Molecular and biochemical events during differentiation of the HD3 chicken erythroblastic cell line. G6PDH, GAD, Hb
478  2003 Molecular evidence for transferrin receptor 2 expression in all FAB subtypes of acute myeloid leukemia. AML
479  2003 Mutational suppression of transferrin receptor shedding can be compensated by distinct metalloproteases acting on alternative sites. ---
480  2003 Nitric oxide inhibits H2O2-induced transferrin receptor-dependent apoptosis in endothelial cells: Role of ubiquitin-proteasome pathway. ---
481  2003 Nitric oxide-mediated modulation of iron regulatory proteins: implication for cellular iron homeostasis. IFN-gamma, IREs, LPS, UTR
482  2003 Oxidative stress-induced iron signaling is responsible for peroxide-dependent oxidation of dichlorodihydrofluorescein in endothelial cells: role of transferrin receptor-dependent iron uptake in apoptosis. DCF, DCFH
483  2003 Phagosomal maturation and intracellular survival of Mycobacterium avium subspecies paratuberculosis in J774 cells. M. a. ptb
484  2003 Plasma levels of soluble transferrin receptors and Clara cell protein (CC16) during bipolar mania and subsequent remission. YMRS
485  2003 Post-transcriptional expression of DMT1 in the heart of rat. DMT1, IRE, NTBI, PND
486  2003 Push/pull mechanisms of GLUT4 traffic in muscle cells. GLUT4
487  2003 Regular consumption of NaFeEDTA-fortified fish sauce improves iron status and reduces the prevalence of anemia in anemic Vietnamese women. SF
488  2003 Role of nitric oxide in cellular iron metabolism. IFN-gamma, IREs, LPS, UTR
489  2003 Soluble transferrin receptor for the evaluation of erythropoiesis and iron status. CLL, sTfR
490  2003 Structures of host range-controlling regions of the capsids of canine and feline parvoviruses and mutants. CPV, FPV
491  2003 The dopamine transporter constitutively internalizes and recycles in a protein kinase C-regulated manner in stably transfected PC12 cell lines. DAT, PKC
492  2003 The natural host range shift and subsequent evolution of canine parvovirus resulted from virus-specific binding to the canine transferrin receptor. CPV
493  2003 Thrombin preconditioning attenuates brain edema induced by erythrocytes and iron. HIF-1alpha, Tf, TPC
494  2003 Transcytosis of GCSF-transferrin across rat alveolar epithelial cell monolayers. A-to-B, BFA
495  2003 Transferrin receptor 1 is differentially required in lymphocyte development. ---
496  2003 Transferrin receptor in children and its correlation with iron status and types of milk consumption. MCV
497  2003 Variable tissue expression of transferrin receptors: relevance to acute respiratory distress syndrome. ARDS, LPS, mRNA
498  2003 [Clinical significance of determining the soluble transferrin receptor]. HP
499  2003 [Effect of nitric oxide on iron metabolism in rats with anemia of chronic disease]. ACD, NO, TIBC, TS
500  2003 [Effect of T3 on the expression of transferrin receptor and ferritin in K562 cells and its possible mechanism]. Fn, IRE, IRP
501  2003 [The effect of erythropoitin and thyroid hormone on K562 iron metabolism]. rhEPO
502  2004 1-Methyl-4-phenylpyridinium-induced apoptosis in cerebellar granule neurons is mediated by transferrin receptor iron-dependent depletion of tetrahydrobiopterin and neuronal nitric-oxide synthase-derived superoxide. nNOS
503  2004 Alpha-synuclein up-regulation and aggregation during MPP+-induced apoptosis in neuroblastoma cells: intermediacy of transferrin receptor iron and hydrogen peroxide. ---
504  2004 Apotransferrin is internalized and distributed in the same way as holotransferrin in K562 cells. apoTf, FCA, LSCM, Tf
505  2004 Ceramide-induced intracellular oxidant formation, iron signaling, and apoptosis in endothelial cells: protective role of endogenous nitric oxide. BAECs, l-NAME, ROS
506  2004 Characterization and modulation of the transferrin receptor on brain capillary endothelial cells. 125I-Tf, BCECs, DFO, LPS, NAC
507  2004 Decreased transferrin receptor expression by neuromelanin cells in restless legs syndrome. RLS, SN
508  2004 Defective regulation of iron transporters leading to iron excess in the polymorphonuclear leukocytes of patients on maintenance hemodialysis. HD, LF, mRNA, PMNLs
509  2004 Degradation of AP2 during reticulocyte maturation enhances binding of hsc70 and Alix to a common site on TFR for sorting into exosomes. HSC70
510  2004 Differential expression and function of IgA receptors (CD89 and CD71) during maturation of dendritic cells. DC, FcRs, IgA, IgA-R, IL, MHC, MoDC
511  2004 Duodenal HFE expression and hepcidin levels determine body iron homeostasis: modulation by genetic diversity and dietary iron availability. ---
512  2004 Effect of intravenous ascorbic acid medication on serum levels of soluble transferrin receptor in hemodialysis patients. HD, IVAA, rHuEPO, TSAT
513  2004 Effects of AZT on cellular iron homeostasis. AZT, Tf
514  2004 Effects of sham air and cigarette smoke on A549 lung cells: implications for iron-mediated oxidative damage. ---
515  2004 Enhancement of cytotoxicity of artemisinins toward cancer cells by ferrous iron. ---
516  2004 Factors affecting the level and localization of the transferrin receptor in Trypanosoma brucei. ---
517  2004 Folate deficiency does not alter the usefulness of the serum transferrin receptor concentration as an index for the detection of iron deficiency in mexican women during early lactation. ROC
518  2004 Glycosylation and size of IgA1 are essential for interaction with mesangial transferrin receptor in IgA nephropathy. HMC, IgAN
519  2004 HFE and transferrin directly compete for transferrin receptor in solution and at the cell surface. ---
520  2004 Imaging endogenous gene expression in brain cancer in vivo with 111In-peptide nucleic acid antisense radiopharmaceuticals and brain drug-targeting technology. BBB, CAV, GFAP, mRNA, PNA, SA
521  2004 In patients who have stainable iron in the bone marrow an elevated plasma transferrin receptor value may reflect functional iron deficiency. ---
522  2004 Iron accumulation and iron-regulatory protein activity in human hepatoma (HepG2) cells. DFO, IRP, IRPs, NTBI
523  2004 Iron accumulation, iron-mediated toxicity and altered levels of ferritin and transferrin receptor in cultured astrocytes during incubation with ferric ammonium citrate. CHX, DFX, FAC, ROS
524  2004 Low vitamin a intake affects milk iron level and iron transporters in rat mammary gland and liver. DMT1, FPN, Ft
525  2004 Mutually exclusive interactions of EHD1 with GS32 and syndapin II. ---
526  2004 Nef-induced alteration of the early/recycling endosomal compartment correlates with enhancement of HIV-1 infectivity. HIV-1
527  2004 Normalization of striatal tyrosine hydroxylase and reversal of motor impairment in experimental parkinsonism with intravenous nonviral gene therapy and a brain-specific promoter. BBB, GFAP, mAb, NeuN, PILs, TH
528  2004 Organ-specific expression of the lacZ gene controlled by the opsin promoter after intravenous gene administration in adult mice. mAb, PIL
529  2004 Preconception hemoglobin and ferritin concentrations are associated with pregnancy outcome in a prospective cohort of Chinese women. FGR, Hb, LBW, OR, OR
530  2004 Serum transferrin receptor levels in beta-thalassemia trait. beta-TT, IDA, sTfR, sTfR
531  2004 Soluble transferrin receptor and its ratio to erythroblasts in bone marrow may be a new diagnostic tool to distinguish between aplastic and refractory anemia. AA, BM, MDS, RA, sTfRs
532  2004 Structure of the human transferrin receptor-transferrin complex. Tf
533  2004 Supplementation of endothelial cells with mitochondria-targeted antioxidants inhibit peroxide-induced mitochondrial iron uptake, oxidative damage, and apoptosis. BAEC, Mito-Q, MitoVit-E
534  2004 The transepithelial transport of a G-CSF-transferrin conjugate in Caco-2 cells and its myelopoietic effect in BDF1 mice. G-CSF, Tf
535  2004 The transferrin receptor: a potential molecular imaging marker for human cancer. MRI
536  2004 Thrombin preconditioning upregulates transferrin and transferrin receptor and reduces brain edema induced by lysed red blood cells. ICH, RBCs, Tf, TPC
537  2004 Transferrin receptor induction in Toxoplasma gondii-infected HFF is associated with increased iron-responsive protein 1 activity and is mediated by secreted factors. ---
538  2004 Transferrin [corrected] receptor association and endosomal localization of soluble HFE are not sufficient for regulation of cellular iron homeostasis. ---
539  2004 Transferrin-oligomers as potential carriers in anticancer drug delivery. CHO, Mono-Tf-MTX, MTX
540  2004 Transport across a polarized monolayer of Caco-2 cells by transferrin receptor-mediated adenovirus transcytosis. BFA, sCAR
541  2004 Use of combined measures from capillary blood to assess iron deficiency in rural Kenyan children. CRP, Hb, ID, ZPP
542  2004 [Evolution and host variation of the canine parvovirus: molecular basis for the development of a new virus]. CPV, FPV
543  2004 [Serum transferrin receptor in healthy children. Diagnostic yield in ferropenic and infectious anemia]. TfR-F
544  2004 [Transferrin receptor expression of human mesenchymal stem cells and in vitro tracking by autoradiography after transplantation in spinal cord]. hMSCs, MSCs
545  2005 A human biotin acceptor domain allows site-specific conjugation of an enzyme to an antibody-avidin fusion protein for targeted drug delivery. ADEPT, Av
546  2005 A role for transferrin receptor in triggering apoptosis when targeted with gambogic acid. GA
547  2005 Abi1 regulates the activity of N-WASP and WAVE in distinct actin-based processes. EGFR, N-WASP
548  2005 Accelerated recycling of transferrin receptor in Theileria-transformed B cells. EEA1, GDP, PI3K
549  2005 Activation of the epidermal growth factor (EGF) receptor induces formation of EGF receptor- and Grb2-containing clathrin-coated pits. AP-2, EGF, EGFR, MAPK, PI3K, siRNA
550  2005 Addition of calcite reduces iron's bioavailability in the Pennsylvania coals--potential use of calcite for the prevention of coal workers' lung diseases. AMs, BAI, LMW, RT-PCR
551  2005 Alteration at translational but not transcriptional level of transferrin receptor expression following manganese exposure at the blood-CSF barrier in vitro. CSF, hnRNA, IRPs
552  2005 Altered expression of iron transport proteins in streptozotocin-induced diabetic rat kidney. ROS
553  2005 Assessing transferrin modification of liposomes by atomic force microscopy and transmission electron microscopy. AFM, TEM, Tf
554  2005 CART: an Hrs/actinin-4/BERP/myosin V protein complex required for efficient receptor recycling. CART, EGFR
555  2005 Changes in erythropoiesis in hereditary hemochromatosis are not mediated by HFE expression in nucleated red cells. ---
556  2005 Comparison of monomeric and oligomeric transferrin as potential carrier in oral delivery of protein drugs. STZ, Tf
557  2005 Comparison of the efficacy of wheat-based snacks fortified with ferrous sulfate, electrolytic iron, or hydrogen-reduced elemental iron: randomized, double-blind, controlled trial in Thai women. SF
558  2005 Construction of single chain Fv antibody against transferrin receptor and its protein fusion with alkaline phosphatase. AP, IFA, SDS-PAGE, SOE-PCR
559  2005 Delivery of beta-galactosidase to mouse brain via the blood-brain barrier transferrin receptor. BBB, mAb
560  2005 Development and brain delivery of chitosan-PEG nanoparticles functionalized with the monoclonal antibody OX26. BBB, CS, NPs, PEG
561  2005 Do cancer cells selectively mutate HFE to increase their intracellular iron? C282Y, NSCLC, PCR-SSCP
562  2005 Engagement of transferrin receptor by polymeric IgA1: evidence for a positive feedback loop involving increased receptor expression and mesangial cell proliferation in IgA nephropathy. HMC, IgAN, pIgA1
563  2005 Evidence for an association between compound heterozygosity for germ line mutations in the hemochromatosis (HFE) gene and increased risk of colorectal cancer. HFE
564  2005 Extracellular H2O2 and not superoxide determines the compartment-specific activation of transferrin receptor by iron regulatory protein 1. IRP1
565  2005 Fatty acid-mediated intracellular iron translocation: a synergistic mechanism of oxidative injury. PA, ROS
566  2005 Glucose-induced regulation of novel iron transporters in vascular endothelial cell dysfunction. DMT1, IREG-1
567  2005 Hemoglobin and ferritin are currently the most efficient indicators of population response to iron interventions: an analysis of nine randomized controlled trials. Hb, MCV, SDU, TS, ZPP
568  2005 Imaging gene expression in regional brain ischemia in vivo with a targeted [111in]-antisense radiopharmaceutical. GFAP, mAb, MCAO, PNA
569  2005 Immunological study of complex formation between soluble transferrin receptor and transferrin. sTfR, Tf
570  2005 Increased divalent metal transporter 1 expression might be associated with the neurotoxicity of L-DOPA. DMT1
571  2005 Increased manganese uptake by primary astrocyte cultures with altered iron status is mediated primarily by divalent metal transporter. AGM, CN, ID, Mn
572  2005 Increased transferrin receptor expression following 11q23 deletion as a mechanism of malignant progression in chronic lymphocytic leukemia. CLL
573  2005 Iron regulates T-lymphocyte sensitivity to the IFN-gamma/STAT1 signaling pathway in vitro and in vivo. DFO, IFN-gamma, SCID, STAT1
574  2005 Manganese oxidation state mediates toxicity in PC12 cells. CuZnSOD, LDH, Mn, MnSOD
575  2005 Microcytic anemia, erythropoietic protoporphyria, and neurodegeneration in mice with targeted deletion of iron-regulatory protein 2. ALAS2, IRPs
576  2005 Mitochondria superoxide dismutase mimetic inhibits peroxide-induced oxidative damage and apoptosis: role of mitochondrial superoxide. BAEC, CP, EPR, Mito-CP
577  2005 Nickel decreases cellular iron level and converts cytosolic aconitase to iron-regulatory protein 1 in A549 cells. DMT1, HEK, HIF-1alpha, Ni
578  2005 Phosphorylation of ACAP1 by Akt regulates the stimulation-dependent recycling of integrin beta1 to control cell migration. ---
579  2005 Prevalence of iron deficiency and anemia among strenuously trained adolescents. Hb
580  2005 Regulatory networks for the control of body iron homeostasis and their dysregulation in HFE mediated hemochromatosis. DMT1, IRP
581  2005 Release of the soluble transferrin receptor is directly regulated by binding of its ligand ferritransferrin. ---
582  2005 Serum transferrin receptor and zinc protoporphyrin as indicators of iron status in African children. CRP, IDA, ROC, SF, ZnPP
583  2005 Single particle reconstruction of the human apo-transferrin-transferrin receptor complex. apoTf, dTf, Tf
584  2005 Sodium ascorbate (vitamin C) induces apoptosis in melanoma cells via the down-regulation of transferrin receptor dependent iron uptake. DFO, FAC
585  2005 The anemia of familial Mediterranean fever disease. ESR, FMF, Hb, sTfR
586  2005 The influence of high iron diet on rat lung manganese absorption. BALT, DMT1
587  2005 Trans-Golgi network syntaxin 10 functions distinctly from syntaxins 6 and 16. siRNA, SNARE, TGN
588  2005 Transferrin receptor-1 and 2 expression in chronic lymphocytic leukemia. ---
589  2005 Treatment with nerve growth factor decreases expression of divalent metal transporter 1 and transferrin receptor in PC12 cells. DMT1, NGF, NTBI
590  2005 TTP specifically regulates the internalization of the transferrin receptor. CCP
591  2005 Tumor necrosis factor-alpha-induced iron sequestration and oxidative stress in human endothelial cells. DMT1, FP1, TNF
592  2005 Two mink parvoviruses use different cellular receptors for entry into CRFK cells. ADV, CRFK, MEV, RNAi, shRNAs
593  2005 Tyrosine hydroxylase replacement in experimental Parkinson's disease with transvascular gene therapy. BBB, mAb, PD, PEG, TH
594  2005 Upregulation of transferrin receptor 2 and ferroportin 1 mRNA in the liver of patients with chronic hepatitis C. CH, FP, mRNA, THIS
595  2005 [Soluble expression and target study to brain of anti-TfR ScFv]. Trx
596  2006 A chemical genetics approach for the discovery of apoptosis inducers: from phenotypic cell based HTS assay and structure-activity relationship studies, to identification of potential anticancer agents and molecular targets. IGF-II, Tf, TIP47
597  2006 A manganese-enhanced diet alters brain metals and transporters in the developing rat. DMT1, GABA, Hb, Mn, Tf
598  2006 Altered iron homeostasis involvement in arsenite-mediated cell transformation. CAPE, HOS, IRP
599  2006 Effect of transferrin receptor-targeted liposomal doxorubicin in P-glycoprotein-mediated drug resistant tumor cells. DXR, MDR, P-gp
600  2006 Effects of transferrin receptor blockade on cancer cell proliferation and hypoxia-inducible factor function and their differential regulation by ascorbate. HIF-alpha, mAb, PHD
601  2006 Efficacy of iron fortification compared to iron supplementation among Vietnamese schoolchildren. CRP, SF
602  2006 Efficient delivery of a Bcl-2-specific antisense oligodeoxyribonucleotide (G3139) via transferrin receptor-targeted liposomes. ODN
603  2006 Enhanced expression of transferrin receptor confers UV-resistance in human and monkey cells. ---
604  2006 Evidence for non-HFE linked hemochromatosis in Asian Indians. HFE1
605  2006 Expression and polarized localization of the hemochromatosis gene product HFE in retinal pigment epithelium. beta2m
606  2006 Expression of iron transport proteins divalent metal transporter-1, Ferroportin-1, HFE and transferrin receptor-1 in human monocyte-derived dendritic cells. DCs, DMT1
607  2006 Fortifying milk with ferrous gluconate and zinc oxide in a public nutrition program reduced the prevalence of anemia in toddlers. FM, NFM
608  2006 Functional interaction between nitric oxide-induced iron homeostasis and heme oxygenase-1 in immortalized and malignant oral keratinocytes. FC, HO-1, IRP, SNP
609  2006 Gallium-induced cell death in lymphoma: role of transferrin receptor cycling, involvement of Bax and the mitochondria, and effects of proteasome inhibition. ---
610  2006 Induction of the transferrin receptor gene by benzo[a]pyrene in breast cancer MCF-7 cells: potential as a biomarker of PAH exposure. AhR, ANF, B2M, PAHs, PAX3
611  2006 Insulin-regulated aminopeptidase marks an antigen-stimulated recycling compartment in mast cells. IgE, IRAP
612  2006 Intracellular survival and replication of Neisseria meningitidis in human brain microvascular endothelial cells. B-CSF, HBMEC, MC, NCV
613  2006 Iron chelators reduce chromosomal breaks in ataxia-telangiectasia cells. AT, rATM
614  2006 Iron regulatory protein-independent regulation of ferritin synthesis by nitrogen monoxide. IREs, SNP
615  2006 Iron status of inner-city African-American infants. FEP
616  2006 Issues in confocal microscopy for quantitative FRET analysis. Tfn
617  2006 Manganese and iron transport across pulmonary epithelium. BALT, Tf
618  2006 Measurement of reticulocyte hemoglobin content to diagnose iron deficiency in Saudi children. Hb, MCH
619  2006 Molecular mechanism of distorted iron regulation in the blood-CSF barrier and regional blood-brain barrier following in vivo subchronic manganese exposure. BBB, CSF, Ft, IRPs, Mn
620  2006 NADPH oxidase inhibitor diphenyliodonium abolishes lipopolysaccharide-induced down-regulation of transferrin receptor expression in N2a and BV-2 cells. AG, DPI, iNOS, LPS, NAC, NO, ROS, TLR4
621  2006 Neonatal erythropoiesis and subsequent anemia in HIV-positive and HIV-negative Zimbabwean babies during the first year of life: a longitudinal study. EPO
622  2006 Properties regulating the nature of the plasmacytoid dendritic cell response to Toll-like receptor 9 activation. IFN, LAMP, pDCs, TLR
623  2006 Purified feline and canine transferrin receptors reveal complex interactions with the capsids of canine and feline parvoviruses that correspond to their host ranges. CPV, FPV
624  2006 Radioprotective effect of transferrin targeted citicoline liposomes. BBB, DPPC, DSPC, HUVEC
625  2006 Reduction of iron-regulated amyloid precursor protein and beta-amyloid peptide by (-)-epigallocatechin-3-gallate in cell cultures: implications for iron chelation in Alzheimer's disease. AD, APP, EGCG
626  2006 Role of HIF-1 in iron regulation: potential therapeutic strategy for neurodegenerative disorders. HIF, HO-1, HREs, IREs, IRPs
627  2006 Salt dual-fortified with iodine and micronized ground ferric pyrophosphate affects iron status but not hemoglobin in children in Cote d'Ivoire. DFS, FePP, IS, SF
628  2006 The high-affinity immunoglobulin-E receptor (FcepsilonRI) is endocytosed by an AP-2/clathrin-independent, dynamin-dependent mechanism. AP-2, DNP-HSA, IgE
629  2006 The transferrin receptor part I: Biology and targeting with cytotoxic antibodies for the treatment of cancer. Tf
630  2006 The transferrin receptor part II: targeted delivery of therapeutic agents into cancer cells. Tf
631  2006 [Expression, purification and activity analysis of anti-human transferrin receptor scFv]. ---
632  2006 [Immunoglobulin A (IgA) and its cellular receptors: Recent advances and new pathogenetical hypothesis]. IgA
633  2006 [Screening and identification of antibodies against transferrin receptor]. ---
634  2007 A 18F-FDG-positive, 67Ga-negative, and transferrin receptor expression-negative patient with diffuse large B-cell lymphoma. DLBCL
635  2007 Accumulation of transferrin in Caco-2 cells: a possible mechanism of intestinal transferrin absorption. 125I-Tf
636  2007 Anemia and intestinal parasite infection in school children in rural Vietnam. CRP, Hb, IgE, SF
637  2007 Angiotensin II-induced regulation of the expression and localization of iron metabolism-related genes in the rat kidney. DMT1, PCR
638  2007 Antibody to AP1B adaptor blocks biosynthetic and recycling routes of basolateral proteins at recycling endosomes. FRT, GFP, LDLR, PM, RE, TGN, VSV-G
639  2007 AP1B sorts basolateral proteins in recycling and biosynthetic routes of MDCK cells. MDCK, mu1B
640  2007 Brain targeting using novel lipid nanovectors. LNC, OX26 MAb
641  2007 Chloroquine is therapeutic in murine experimental model of paracoccidioidomycosis. IL, TNF-alpha
642  2007 Chronic brain cytochrome oxidase inhibition selectively alters hippocampal cholinergic innervation and impairs memory: prevention by ladostigil. AD, ChAT, COX, VAChT
643  2007 Colocalization of ferroportin-1 with hephaestin on the basolateral membrane of human intestinal absorptive cells. FPN1, Heph
644  2007 Design of targeted lipid nanocapsules by conjugation of whole antibodies and antibody Fab' fragments. LNC, OX26 MAb
645  2007 Development of gallium compounds for treatment of lymphoma: gallium maltolate, a novel hydroxypyrone gallium compound, induces apoptosis and circumvents lymphoma cell resistance to gallium nitrate. MoAb, ROS
646  2007 Dietary inulin affects the expression of intestinal enterocyte iron transporters, receptors and storage protein and alters the microbiota in the pig intestine. DMT1
647  2007 Different mechanisms of antibody-mediated neutralization of parvoviruses revealed using the Fab fragments of monoclonal antibodies. ---
648  2007 Downregulation of transferrin receptor surface expression by intracellular antibody. ER
649  2007 Elevated serum erythropoietin concentration is associated with coordinated changes in red blood cell and reticulocyte indices of pregnant women at term. CHm, EPO
650  2007 Evolution of the iron-responsive element. DMT1, eALAS, IRE, IRPs, mAco, sea anemone
651  2007 Hypoxia: dual effect on the expression of transferrin receptor in human melanoma A375 cell line. ---
652  2007 Identification and characterization of tumor antigens by using antibody phage display and intrabody strategies. CD9P-1
653  2007 Interpreting tests for iron deficiency among adults in a high HIV prevalence African setting: routine tests may lead to misdiagnosis. LR
654  2007 Intravenous glial-derived neurotrophic factor gene therapy of experimental Parkinson's disease with Trojan horse liposomes and a tyrosine hydroxylase promoter. GDNF, mAb, PD, Pro, TH, THLs
655  2007 Iron/IRP-1-dependent regulation of mRNA expression for transferrin receptor, DMT1 and ferritin during human erythroid differentiation. DMT1, EMSA, EPO, IGF-I, IREs, IRP, SCF
656  2007 Myosin VI and its interacting protein LMTK2 regulate tubule formation and transport to the endocytic recycling compartment. LMTK2
657  2007 Prevention of mantle lymphoma tumor establishment by routing transferrin receptor toward lysosomal compartments. MCL
658  2007 Putative proteins involved in manganese transport across the blood-brain barrier. BBB, DMT1, Mn
659  2007 Quantitative flow cytometric analysis of transferrin receptor expression on reticulocytes. ABC, FCM, FID
660  2007 Quantum rod bioconjugates as targeted probes for confocal and two-photon fluorescence imaging of cancer cells. MUA, QRs, Tf
661  2007 Receptor complexes cotransported via polarized endocytic pathways form clusters with distinct organizations. pIgA-R
662  2007 Role of transferrin receptor and the ABC transporters ABCB6 and ABCB7 for resistance and differentiation of tumor cells towards artesunate. ABC, MEL, NCI
663  2007 Roles of hormone replacement therapy and iron in proliferation of breast epithelial cells with different estrogen and progesterone receptor status. PR
664  2007 The effect of iron fortification and de-worming on anaemia and iron status of Vietnamese schoolchildren. CRP, SF
665  2007 The JNK/AP-1 pathway upregulates expression of the recycling endosome rab11a gene in B cells transformed by Theileria. JNK
666  2007 The relationship between red blood cell and reticulocyte indices and serum markers of iron status in the cord blood of newborns. TfSat
667  2007 The transferrin receptor and the tetraspanin web molecules CD9, CD81, and CD9P-1 are differentially sorted into exosomes after TPA treatment of K562 cells. ---
668  2007 Transferrin receptor engagement by polymeric IgA1 induces receptor expression and mesangial cell proliferation: role in IgA nephropathy. HMC, IgAN, pIgA1
669  2007 Transferrin receptor in proliferation of T lymphocytes in infants with iron deficiency. IDA, LID, PHA
670  2007 Tumor cell targeting of transferrin-PEG-TNF-alpha conjugate via a receptor-mediated delivery system: design, synthesis, and biological evaluation. PEG-TNF-alpha, Tf, TPT4
671  2007 Ultravlolet-B induced expression of hypoxia-inducible factor 1alpha, transferrin receptor through EGFR/PI3K/AKT/DEC1 pathway. EGFR, HIF-1alpha, UVB
672  2007 Use of advanced red blood cell and reticulocyte indices improves the accuracy in diagnosing iron deficiency in pregnant women at term. AUC, CHr, Hb, MCV, ROC, TfSat
673  2008 Altered iron metabolism in lymphocytes from subjects with restless legs syndrome. DMT1, RLS
674  2008 An anti-transferrin receptor antibody enhanced the growth inhibitory effects of chemotherapeutic drugs on human non-hematopoietic tumor cells. ---
675  2008 Cell-death-inducing monoclonal antibodies raised against DT40 tumor cells: identification of chicken transferrin receptor as a novel cell-death receptor. mAbs, Tf
676  2008 Comparison of plasma ferritin concentration with the ratio of plasma transferrin receptor to ferritin in estimating body iron stores: results of 4 intervention trials. BI
677  2008 Dihydroartemisinin induces apoptosis in human leukemia cells HL60 via downregulation of transferrin receptor expression. DHA
678  2008 Diminished iron concentrations increase adenosine A(2A) receptor levels in mouse striatum and cultured human neuroblastoma cells. ---
679  2008 Dysregulation of systemic iron metabolism in alcoholic liver diseases. ALD, NASH, Tf
680  2008 Efflux of iron from the cerebrospinal fluid to the blood at the blood-CSF barrier: effect of manganese exposure. CSF, DMT1, Mn
681  2008 Elevated iron stores are associated with HIV disease severity and mortality among postpartum women in Zimbabwe. SF, VL
682  2008 Engineering and expression of a chimeric transferrin receptor monoclonal antibody for blood-brain barrier delivery in the mouse. BBB, HIR, mAb
683  2008 Evaluation of iron deficiency as a nutritional adaptation to infectious disease: an evolutionary medicine perspective. OR, TSF, ZPP
684  2008 Foot-shock stress-induced regional iron accumulation and altered iron homeostatic mechanisms in rat brain. IRP1, LF
685  2008 High concentrations of ascorbic acid induces apoptosis of human gastric cancer cell by p38-MAP kinase-dependent up-regulation of transferrin receptor. AA, MAPK
686  2008 Incorporation of 5-hydroxytryptophan into transferrin and its receptor allows assignment of the pH induced changes in intrinsic fluorescence when iron is released. hTF
687  2008 Influence of inflammation as measured by alpha-1-acid glycoprotein on iron status indicators among HIV-positive postpartum Zimbabwean women. AGP, APR, EPO, Hb, SF
688  2008 Insulin induces the low density lipoprotein receptor-related protein 1 (LRP1) degradation by the proteasomal system in J774 macrophage-derived cells. LRP1
689  2008 Intracellular localization and subsequent redistribution of metal transporters in a rat choroid plexus model following exposure to manganese or iron. CSF, DMT1, Mn, MTP1
690  2008 Iron chelator-based amplification strategy for improved targeting of transferrin receptor with SPIO. DFO, MR, SPIO
691  2008 Isolation of rafts from mouse brain tissue by a detergent-free method. Flot1
692  2008 Molecular mimicry and immunomodulation by the HRES-1 endogenous retrovirus in SLE. ERV, IS, SLE, TCR-zeta
693  2008 Molecular scintigraphic imaging using 99mTc-transferrin is useful for early detection of synovial inflammation of collagen-induced arthritis mouse. 99mTc-MDP, 99mTc-Tf, CIA
694  2008 Near complete rescue of experimental Parkinson's disease with intravenous, non-viral GDNF gene therapy. GDNF, mAb, PD, TH, THLs
695  2008 Protein components of the blood-brain barrier (BBB) in the mediobasal hypothalamus. AgRP, BBB, CVO, DARPP-32, EBA, GFAP, GLUT1, RECA-1, SMA, ZO-1
696  2008 Protein kinase d regulates trafficking of dendritic membrane proteins in developing neurons. LRP, PKD, TGN
697  2008 Selective regulation of the perinuclear distribution of glucose transporter 4 (GLUT4) by insulin signals in muscle cells. AS160, GLUT4, VAMP2
698  2008 Simultaneous induction of apoptotic, autophagic, and necrosis-like cell death by monoclonal antibodies recognizing chicken transferrin receptor. PCD
699  2008 Structure of the membrane proximal oxidoreductase domain of human Steap3, the dominant ferrireductase of the erythroid transferrin cycle. Tf
700  2008 Synthesis and evaluation of novel polyaminocarboxylate-based antitumor agents. C-NE3TA and N-NE3TA, RR
701  2008 Targeting hypoxia-inducible factor-1alpha with Tf-PEI-shRNA complex via transferrin receptor-mediated endocytosis inhibits melanoma growth. HIF-1alpha, MM, siRNA, Tf-PEI-HIF-1alpha-shRNA
702  2008 Targeting of the CNS in MPS-IH using a nonviral transferrin-alpha-L-iduronidase fusion gene product. CNS, GAG, IDUA, MPS I, Tf
703  2008 Targeting of the CNS in MPS-IH Using a Nonviral Transferrin-α-l-iduronidase Fusion Gene Product. CNS, GAG, IDUA, MPS I, Tf
704  2008 The glomerular response to IgA deposition in IgA nephropathy. ---
705  2008 The role of Hfe in transferrin-bound iron uptake by hepatocytes. mRNA
706  2008 The role of iron dysregulation in the pathogenesis of multiple sclerosis: an Egyptian study. MS, PP, RR-A, SP, SP-A, SP-S, sTfR
707  2008 Transferrin receptor-dependent cytotoxicity of artemisinin-transferrin conjugates on prostate cancer cells and induction of apoptosis. ART-Tf, Tf
708  2008 Transferrin-receptor-mediated iron accumulation controls proliferation and glutamate release in glioma cells. ---
709  2008 Use of red blood cell indices for the identification of iron deficiency among blood donors. RBC
710  2008 Visualizing head and neck tumors in vivo using near-infrared fluorescent transferrin conjugate. HNSCCs, TfNIR
711  2008 [Dihydroartemisinin down-regulates the expression of transferrin receptor in myeloid leukemia cells]. DHA
712  2009 Abnormal brain iron homeostasis in human and animal prion disorders. sCJD, Tf
713  2009 Adjusting for the acute phase response is essential to interpret iron status indicators among young Zanzibari children prone to chronic malaria and helminth infections. AGP, APP, APR, CRP, EPO, Hb, ZPP
714  2009 Chlamydia trachomatis alters iron-regulatory protein-1 binding capacity and modulates cellular iron homeostasis in HeLa-229 cells. CT, IREs, IRP
715  2009 Cu loading alters expression of non-IRE regulated, but not IRE regulated, Fe dependent proteins in HepG2 cells. Cp, Tf
716  2009 Cytoplasmic phospholipase A2 antagonists inhibit multiple endocytic membrane trafficking pathways. EGF, ERC, LDLR, ONO, SEs, Tf
717  2009 Delivery of antisense oligodeoxyribonucleotide lipopolyplex nanoparticles assembled by microfluidic hydrodynamic focusing. BM, cryo-TEM, DLS, LP, MF, zeta
718  2009 Early steps in cell infection by parvoviruses: host-specific differences in cell receptor binding but similar endosomal trafficking. CPV, FPV
719  2009 Efficacy of different iron fortificants in wheat flour in controlling iron deficiency. Hb, SF
720  2009 Engineering and characterization of a baculovirus-expressed mouse/human chimeric antibody against transferrin receptor. ADCC, CDC, mAb, MAGIC
721  2009 Entry of Porphyromonas gingivalis outer membrane vesicles into epithelial cells causes cellular functional impairment. FAK, IHGE, MVs
722  2009 Human serum transferrin: a tale of two lobes. Urea gel and steady state fluorescence analysis of recombinant transferrins as a function of pH, time, and the soluble portion of the transferrin receptor. hTF, sTFR
723  2009 Loss of myosin VI no insert isoform (NoI) induces a defect in clathrin-mediated endocytosis and leads to caveolar endocytosis of transferrin receptor. ---
724  2009 Maternal pro-hepcidin at term correlates with cord blood pro-hepcidin at birth. TfSat
725  2009 MR reporter gene imaging of endostatin expression and therapy. ES, MR, Tf-USPIO
726  2009 mRNA expression of proteins involved in iron homeostasis in brain regions is altered by age and by iron overloading in the neonatal period. ---
727  2009 Pharmacokinetics and brain uptake of a genetically engineered bifunctional fusion antibody targeting the mouse transferrin receptor. BBB, ID, mAbs, scFv
728  2009 Prion protein modulates cellular iron uptake: a novel function with implications for prion disease pathogenesis. LIP, Tf
729  2009 Procyanidins and butanol extract of Cinnamomi Cortex inhibit SARS-CoV infection. wtSARS-CoV
730  2009 Protein components of the blood-brain barrier (BBB) in the brainstem area postrema-nucleus tractus solitarius region. alpha-MSH, AP, BBB, CVOs, DARPP-32, EBA, GFAP, GLUT1, NPY, NTS, RECA-1, SMA, ZO-1
731  2009 Rab4b is a small GTPase involved in the control of the glucose transporter GLUT4 localization in adipocyte. ---
732  2009 Targeted delivery of doxorubicin using stealth liposomes modified with transferrin. Tf, Tf-SL
733  2009 The first targeted delivery of siRNA in humans via a self-assembling, cyclodextrin polymer-based nanoparticle: from concept to clinic. CDP, PEG, RNAi, siRNA, Tf
734  2009 The role of transferrin receptor 1 and 2 in transferrin-bound iron uptake in human hepatoma cells. TBI, Tf
735  2009 The soluble transferrin receptor (TfR)-F-Index is not applicable as a test for iron status in patients with chronic lymphocytic leukemia. CLL, CRP, ID, sTfR
736  2009 The unique kinetics of iron release from transferrin: the role of receptor, lobe-lobe interactions, and salt at endosomal pH. hTF
737  2009 Transferrin receptor-targeted lipid nanoparticles for delivery of an antisense oligodeoxyribonucleotide against Bcl-2. ---
738  2009 TTP at Ser245 phosphorylation by AKT is required for binding to 14-3-3. TTP
739  2009 [Secreting expression and characterization of canine parvovirus VP2 protein in eukaryotic cells]. SP
740  2010 1-Cinnamoyl-3,11-dihydroxymeliacarpin delays glycoprotein transport restraining virus multiplication without cytotoxicity. CDM
741  2010 A transferrin receptor-targeted liposomal formulation for docetaxel. Chol, DSPE, HSPC, mPEG, PC
742  2010 Acetaldehyde/alcohol dehydrogenase-2 (EhADH2) and clathrin are involved in internalization of human transferrin by Entamoeba histolytica. EhADH2, EhTfbp, holo-Tf, Tf
743  2010 Additive controlled synthesis of gold nanorods (GNRs) for two-photon luminescence imaging of cancer cells. CTAB, GNRs, GNRs, Tf
744  2010 Altered manganese homeostasis and manganese toxicity in a Huntington's disease striatal cell model are not explained by defects in the iron transport system. DMT1, Fe, HD, HTT, Mn
745  2010 Andrographolide regulates epidermal growth factor receptor and transferrin receptor trafficking in epidermoid carcinoma (A-431) cells. EGFR
746  2010 Antibody library screens using detergent-solubilized mammalian cell lysates as antigen sources. ---
747  2010 Brain-penetrating tumor necrosis factor decoy receptor in the mouse. BBB, mAb, TNFis, TNFRs
748  2010 Cloning and tissue expression of the equine transferrin receptor. aa, eTfR, IHC
749  2010 Development of human single-chain antibodies to the transferrin receptor that effectively antagonize the growth of leukemias and lymphomas. scFv
750  2010 Effect of artemisinin derivatives on apoptosis and cell cycle in prostate cancer cells. PCa
751  2010 Evaluation of two internalizing carcinoembryonic antigen reporter genes for molecular imaging. CEA, IHC, PET
752  2010 Evidence that His349 acts as a pH-inducible switch to accelerate receptor-mediated iron release from the C-lobe of human transferrin. hTf
753  2010 Extrusion of Na,K-ATPase and transferrin receptor with lipid raft-associated proteins in different populations of exosomes during reticulocyte maturation in dogs. Hsc70
754  2010 Human MRCKalpha is regulated by cellular iron levels and interferes with transferrin iron uptake. IRE, Tf, UTR
755  2010 Identification of a kinetically significant anion binding (KISAB) site in the N-lobe of human serum transferrin. hTF, KISAB
756  2010 Impact of maternal and neonatal iron status on placental transferrin receptor expression in pregnant adolescents. ---
757  2010 Impairment of protein trafficking upon overexpression and mutation of optineurin. L157A, RGCs, RPE, Tf
758  2010 Improvement in lipid and protein trafficking in Niemann-Pick C1 cells by correction of a secondary enzyme defect. BMP, NPC1, SMase
759  2010 In vitro and initial in vivo evaluation of (68)Ga-labeled transferrin receptor (TfR) binding peptides as potential carriers for enhanced drug transport into TfR expressing cells. BBB
760  2010 Intravenous treatment of experimental Parkinson's disease in the mouse with an IgG-GDNF fusion protein that penetrates the blood-brain barrier. BBB, GDNF, mAb, PD, TH
761  2010 Iron uptake from plasma transferrin by a transferrin receptor 2 mutant mouse model of haemochromatosis. ---
762  2010 Mechanisms of gambogic acid-induced apoptosis in non-small cell lung cancer cells in relation to transferrin receptors. GA
763  2010 Monoclonal antibody-glial-derived neurotrophic factor fusion protein penetrates the blood-brain barrier in the mouse. BBB, GDNF, mAb
764  2010 Myocardial iron metabolism in the regulation of cardiovascular diseases in rats. DM, DMT1, MDA, MI, MTP1, SOD, STZ
765  2010 Neuroprotection in stroke in the mouse with intravenous erythropoietin-Trojan horse fusion protein. BBB, EPO, mAb, MCAO
766  2010 Noncanonical interactions between serum transferrin and transferrin receptor evaluated with electrospray ionization mass spectrometry. ESI-MS, Tf
767  2010 Overcoming cisplatin resistance of ovarian cancer cells by targeted liposomes in vitro. ---
768  2010 Peptide-conjugated PAMAM for targeted doxorubicin delivery to transferrin receptor overexpressed tumors. DOX, NPs, PAMAM, PEG, Tf
769  2010 Re-engineering erythropoietin as an IgG fusion protein that penetrates the blood-brain barrier in the mouse. BBB, EPO, EPOR, mAb
770  2010 Receptor-mediated abeta amyloid antibody targeting to Alzheimer's disease mouse brain. AAA, AD, BBB, mAb, scFv
771  2010 Systemic combinatorial peptide selection yields a non-canonical iron-mimicry mechanism for targeting tumors in a mouse model of human glioblastoma. BBB
772  2010 Temozolomide delivery to tumor cells by a multifunctional nano vehicle based on poly(beta-L-malic acid). TMZ
773  2010 Transferrin receptor expression on reticulocytes as a marker of iron status in dialyzed patients. ABC, CHr, CRF, FID, Hb
774  2010 Transient expression of iron transport proteins in the capillary of the developing rat brain. BBB
775  2010 [Research advance on transferrin receptor in hematological malignant tumor treatment]. ---
776  2011 A novel transferrin receptor-targeted hybrid peptide disintegrates cancer cell membrane to induce rapid killing of cancer cells. ---
777  2011 An anti-transferrin receptor antibody enhanced the growth inhibitory effects of chemotherapeutic drugs on human glioma cells. FCM, mAb, PI
778  2011 Association study between four polymorphisms in the HFE, TF and TFR genes and Parkinson's disease in southern Italy. PD, Tf
779  2011 Boosting brain uptake of a therapeutic antibody by reducing its affinity for a transcytosis target. BBB
780  2011 Brain iron dysregulation and the risk of ageing white matter lesions. Cp, IHC, ROS, WML
781  2011 Brain penetrating IgG-erythropoietin fusion protein is neuroprotective following intravenous treatment in Parkinson's disease in the mouse. BBB, EPO, mAb, PD, TH
782  2011 Brain-penetrating IgG-iduronate 2-sulfatase fusion protein for the mouse. IDS, mAb, MPS
783  2011 Chronic dosing of mice with a transferrin receptor monoclonal antibody-glial-derived neurotrophic factor fusion protein. BBB, GDNF, mAb
784  2011 Correcting for inflammation changes estimates of iron deficiency among rural Kenyan preschool children. AGP, APP, CF, CRP, Hb, ZP
785  2011 Delivery of a peptide radiopharmaceutical to brain with an IgG-avidin fusion protein. AD, Av, BBB, ID, mAb
786  2011 Differential expression of transferrin receptor (TfR) in a spectrum of normal to malignant breast tissues: implications for in situ and invasive carcinoma. DCIS
787  2011 Enhanced transferrin receptor expression by proinflammatory cytokines in enterocytes as a means for local delivery of drugs to inflamed gut mucosa. IBDs
788  2011 Fermented soyabean and vitamin C-rich fruit: a possibility to circumvent the further decrease of iron status among iron-deficient pregnant women in Indonesia. ID
789  2011 Glioma growth inhibition in vitro and in vivo by single chain variable fragments of the transferrin receptor conjugated to survivin small interfering RNA. scFv, siRNA
790  2011 How the binding of human transferrin primes the transferrin receptor potentiating iron release at endosomal pH. hTf
791  2011 In vivo labeling of brain capillary endothelial cells after intravenous injection of monoclonal antibodies targeting the transferrin receptor. AF, mAbs
792  2011 Iron and iron regulatory proteins in amoeboid microglial cells are linked to oligodendrocyte death in hypoxic neonatal rat periventricular white matter through production of proinflammatory cytokines and reactive oxygen/nitrogen species. AMCs, IRPs, PWM
793  2011 Kinetics of iron release from transferrin bound to the transferrin receptor at endosomal pH. hTF
794  2011 Neuroprotection with a brain-penetrating biologic tumor necrosis factor inhibitor. BBB, mAb, TH, TNF, TNFR
795  2011 Novel molecular targets of the neuroprotective/neurorescue multimodal iron chelating drug M30 in the mouse brain. BDNF, EPO, GDNF, GLUT, GPx, GSK-3beta, HIF, HO-1, iNOS, MAPK, PKC, SOD, VEGF
796  2011 Proteome of ubiquitin/MVB pathway: possible involvement of iron-induced ubiquitylation of transferrin receptor in lysosomal degradation. MVBs
797  2011 Receptor-mediated activation of a proinsulin-transferrin fusion protein in hepatoma cells. INS, irINS-Tf, ProINS, ProINS-Tf, RIA, Tf, TGN
798  2011 Regulation of brain iron and copper homeostasis by brain barrier systems: implication in neurodegenerative diseases. BBB, BCB, CSF, FPN
799  2011 Reversal of lysosomal storage in brain of adult MPS-I mice with intravenous Trojan horse-iduronidase fusion protein. IDUA, mAb, MPS
800  2011 Small GTPase Rab12 regulates constitutive degradation of transferrin receptor. EGFR, siRNA
801  2011 The effect of soy food intake on mineral status in premenopausal women. TSH
802  2011 The Nicastrin ectodomain adopts a highly thermostable structure. APH-1, CD, Pen-2, SGAP
803  2011 The thermodynamic and binding properties of the transferrins as studied by isothermal titration calorimetry. Tf
804  2011 The transferrin receptor and the targeted delivery of therapeutic agents against cancer. ---
805  2011 Vitamin A deficiency aggravates iron deficiency by upregulating the expression of iron regulatory protein-2. Fn, IRP2
806  2011 [Regulating action of iron regulatory protein-2 in iron metabolism of lung cancer]. ASODN group, Fn, IRP2, RT-PCR, Tf
807  2012 3D single molecule tracking with multifocal plane microscopy reveals rapid intercellular transferrin transport at epithelial cell barriers. ---
808  2012 A reverse complementary multimodal imaging system to visualize microRNA9-involved neurogenesis using peptide targeting transferrin receptor-conjugated magnetic fluorescence nanoparticles. MF
809  2012 Antibody affinity maturation using yeast display with detergent-solubilized membrane proteins as antigen sources. MPs
810  2012 Biochemical and structural characterization of recombinant human serum transferrin from rice (Oryza sativa L.). hTF
811  2012 Brain protection from stroke with intravenous TNFalpha decoy receptor-Trojan horse fusion protein. BBB, mAb, TNF, TNFis, TNFR
812  2012 Ceruloplasmin alters intracellular iron regulated proteins and pathways: ferritin, transferrin receptor, glutamate and hypoxia-inducible factor-1alpha. Cp, HIF1, IRP, LEC, LIP, RPE
813  2012 Characterization of transferrin receptor-mediated endocytosis and cellular iron delivery of recombinant human serum transferrin from rice (Oryza sativa L.). hTF, rhTF, Tf
814  2012 Comparative binding, endocytosis, and biodistribution of antibodies and antibody-coated carriers for targeted delivery of lysosomal enzymes to ICAM-1 versus transferrin receptor. ASM, ERTs, ICAM-1
815  2012 Delivery system for the enhanced efficiency of immunostimulatory nucleic acids. INAs, PLL, Tf, TLRs
816  2012 Early life iron deficiency impairs spatial cognition in neonatal piglets. CON, MID, SID
817  2012 Evaluation of diagnostic efficacy of serum sTfR assay in iron-deficiency anemia and Beta-thalassemia trait in Shafa hospital, Ahvaz, Iran 2010. beta-TT, CBC, IDA, sTfR
818  2012 Evolutionary reconstructions of the transferrin receptor of Caniforms supports canine parvovirus being a re-emerged and not a novel pathogen in dogs. ---
819  2012 Expression and function of ferroportin 1 in O-2A progenitor cells. FPN1, Ft
820  2012 Generation and functional characterization of the anti-transferrin receptor single-chain antibody-GAL4 (TfRscFv-GAL4) fusion protein. FCM, GFP, scFv, TMA
821  2012 Interleukin-6 and lipopolysaccharide modulate hepcidin mRNA expression by HepG2 cells. Hpc
822  2012 Iron supplementation is positively associated with increased serum ferritin levels in 9-month-old Danish infants. ---
823  2012 Ischemic preconditioning attenuates brain edema after experimental intracerebral hemorrhage. HO-1, ICH, IPC, MAPKs, Tf
824  2012 Limited transferrin receptor clustering allows rapid diffusion of canine parvovirus into clathrin endocytic structures. CPV
825  2012 Mass spectrometry study of a transferrin-based protein drug reveals the key role of protein aggregation for successful oral delivery. GHT
826  2012 Mechanistic analysis of iron accumulation by endothelial cells of the BBB. BBB, EC, HBMVEC, NTBI, TBI
827  2012 Multi-micronutrient-fortified biscuits decreased the prevalence of anaemia and improved iron status, whereas weekly iron supplementation only improved iron status in Vietnamese school children. FB, PF, SUP
828  2012 Nanobiopolymer for direct targeting and inhibition of EGFR expression in triple negative breast cancer. AON, EGFR, mAb, PMLA, TNBC
829  2012 Overweight impairs efficacy of iron supplementation in iron-deficient South African children: a randomized controlled intervention. BAZ, CRP, ID, OR, OW, SF, ZnPP
830  2012 Ovine uterine space restriction alters placental transferrin receptor and fetal iron status during late pregnancy. eNOS, GD, NO, NSR, USR
831  2012 Rab10 and myosin-Va mediate insulin-stimulated GLUT4 storage vesicle translocation in adipocytes. IRAP, PM, TIRF
832  2012 Rationally designed aberrant kinase-targeted endogenous protein nanomedicine against oncogene mutated/amplified refractory chronic myeloid leukemia. CML, HSA, IM, SMI, Tf, Tf-nAlb-Soraf
833  2012 Recent advances in receptor-targeted fluorescent probes for in vivo cancer imaging. EGF, ER, FR, GRP, HER2, LDL, NIR, SSTRs, TSPO, uPA, VEGF, VIP
834  2012 Recycling endosomes contribute to autophagosome formation. RE, TBC, Tf
835  2012 Reengineering biopharmaceuticals for targeted delivery across the blood-brain barrier. BBB, HIR, mAb, MTH, PK
836  2012 Selective plasma pharmacokinetics and brain uptake in the mouse of enzyme fusion proteins derived from species-specific receptor-targeted antibodies. BBB, HIR, IDS, mAb
837  2012 Sinomenine hydrochloride enhancement of the inhibitory effects of anti-transferrin receptor antibody-dependent on the COX-2 pathway in human hepatoma cells. mAb
838  2012 Small GTPase Rab12 regulates transferrin receptor degradation: Implications for a novel membrane trafficking pathway from recycling endosomes to lysosomes. ---
839  2012 Structure and dynamics of drug carriers and their interaction with cellular receptors: focus on serum transferrin. ---
840  2012 The PICALM protein plays a key role in iron homeostasis and cell proliferation. MEFs, PICALM
841  2012 Transferrin receptor specific nanocarriers conjugated with functional 7peptide for oral drug delivery. ---
842  2012 Transferrin-mediated cellular iron delivery. hTF
843  2012 Transport of a caspase inhibitor across the blood-brain barrier by chitosan nanoparticles. BBB
844  2012 [Construction and validation of dual fusion reporter gene expression vector for molecular imaging study]. EGFP, MR
845  2013 Addressing safety liabilities of TfR bispecific antibodies that cross the blood-brain barrier. ---
846  2013 Arf6, Rab11 and transferrin receptor define distinct populations of recycling endosomes. ---
847  2013 Brain uptake of a fluorescent vector targeting the transferrin receptor: a novel application of in situ brain perfusion. AF750, BBB, mAbs
848  2013 Canine and feline parvoviruses preferentially recognize the non-human cell surface sialic acid N-glycolylneuraminic acid. CPV, FPV
849  2013 Combination stroke therapy in the mouse with blood-brain barrier penetrating IgG-GDNF and IgG-TNF decoy receptor fusion proteins. BBB, GDNF, mAb, MCAO, TNFR
850  2013 Construction and identification of the adenoviral vector with dual reporter gene for multimodality molecular imaging. Ad, MR, pAdeno, PCR, TFRC
851  2013 Disaggregation of amyloid plaque in brain of Alzheimer's disease transgenic mice with daily subcutaneous administration of a tetravalent bispecific antibody that targets the transferrin receptor and the Abeta amyloid peptide. AAA, AD, APP, BBB, mAb, PS, s.c, scFv
852  2013 Evaluation and comparison of soluble transferrin receptor in thalassemia carriers and iron deficient patients. Hb, SPSS, sTfR, sTfR-F index
853  2013 Expression of curcin-transferrin receptor binding peptide fusion protein and its anti-tumor activity. ---
854  2013 Fabrication of transferrin functionalized gold nanoclusters/graphene oxide nanocomposite for turn-on near-infrared fluorescent bioimaging of cancer cells and small animals. GO, NIR, Tf
855  2013 Immunogenicity and toxicity of transferrin receptor-targeted hybrid peptide as a potent anticancer agent. ---
856  2013 In vivo performance of polymer nanocarriers dually-targeted to epitopes of the same or different receptors. ICAM-1
857  2013 Increasing dietary protein acutely augments intestinal iron transporter expression and significantly increases iron absorption in rats. DMT1
858  2013 Iron accumulates in Huntington's disease neurons: protection by deferoxamine. FPN, HD
859  2013 Iron-metabolic function and potential antibacterial role of Hepcidin and its correlated genes (Ferroportin 1 and Transferrin Receptor) in turbot (Scophthalmus maximus). FPN1
860  2013 Ligand-mediated endocytosis of nanoparticles in neural stem cells: implications for cellular magnetic resonance imaging. NSCs, Tf, TfR-NSC, USPIOs
861  2013 Mechanism of poly-l-lysine-modified iron oxide nanoparticles uptake into cells. ---
862  2013 Membrane-associated RING-CH (MARCH) 8 mediates the ubiquitination and lysosomal degradation of the transferrin receptor. MARCH, Tf
863  2013 Methods of analysis of the membrane trafficking pathway from recycling endosomes to lysosomes. ---
864  2013 Oral administration of Bifidobacterium longum CECT 7347 ameliorates gliadin-induced alterations in liver iron mobilisation. IFN
865  2013 Pharmacokinetics and brain uptake of an IgG-TNF decoy receptor fusion protein following intravenous, intraperitoneal, and subcutaneous administration in mice. BBB, i.p, mAb, TNF, TNFR
866  2013 Phase I study of a systemically delivered p53 nanoparticle in advanced solid tumors. SGT-53
867  2013 Quantitative subcellular study of transferrin receptor-targeted doxorubicin and its metabolite in human breast cancer cells. DOX, DOX-TRF, DOXol
868  2013 Receptor recognition of transferrin bound to lanthanides and actinides: a discriminating step in cellular acquisition of f-block metals. Ln, Tf
869  2013 Soluble form of canine transferrin receptor inhibits canine parvovirus infection in vitro and in vivo. CPV, sTfR
870  2013 Study of the transcytosis of an anti-transferrin receptor antibody with a Fab' cargo across the blood-brain barrier in mice. BBB, FRET, ICs
871  2013 Synergistic targeted delivery of payload into tumor cells by dual-ligand liposomes co-modified with cholesterol anchored transferrin and TAT. PEG, Tf
872  2013 Targeted transferrin-modified polymeric micelles: enhanced efficacy in vitro and in vivo in ovarian carcinoma. CDK, Tf
873  2013 The kinesin KIF16B mediates apical transcytosis of transferrin receptor in AP-1B-deficient epithelia. ARE, CRE, PM
874  2013 The secreted oligomeric form of alpha-synuclein affects multiple steps of membrane trafficking. alpha-syn
875  2013 Transferrin serves as a mediator to deliver organometallic ruthenium(II) anticancer complexes into cells. hTf
876  2013 [Effects of different zinc nutritional status on iron metabolism in rats]. Fn, IRP2, PF group, RT-PCR, ZE group
877  2014 A human blood-brain barrier transcytosis assay reveals antibody transcytosis influenced by pH-dependent receptor binding. IGF1R
878  2014 A liquid chromatography-tandem mass spectrometry-based targeted proteomics approach for the assessment of transferrin receptor levels in breast cancer. ---
879  2014 A novel antibiotic-delivery system by using ovotransferrin as targeting molecule. DHFR, FabI, OTf, TCS
880  2014 Anthropometric and micronutrient status of school-children in an urban West Africa setting: a cross-sectional study in Dakar (Senegal). FER, RBP
881  2014 Blood-brain barrier drug delivery of IgG fusion proteins with a transferrin receptor monoclonal antibody. BBB
882  2014 Changes in soluble transferrin receptor and hemoglobin concentrations in Malawian mothers are associated with those values in their exclusively breastfed, HIV-exposed infants. LNS
883  2014 Dual single-scission event analysis of constitutive transferrin receptor (TfR) endocytosis and ligand-triggered beta2-adrenergic receptor (beta2AR) or Mu-opioid receptor (MOR) endocytosis. beta2AR, CCSs, GPCRs, MOR, TIRFM
884  2014 Enterohaemorrhagic Escherichia coli inhibits recycling endosome function and trafficking of surface receptors. EGFR
885  2014 From fast fluorescence imaging to molecular diffusion law on live cell membranes in a commercial microscope. PPE
886  2014 Galectin-4-mediated transcytosis of transferrin receptor. KPT, RPE
887  2014 Host-specific parvovirus evolution in nature is recapitulated by in vitro adaptation to different carnivore species. CPV, FPV
888  2014 Hypoxia induced changes in expression of proteins involved in iron uptake and storage in cultured lens epithelial cells. HIF, HRE, IREs, IRP, LEC, ROS
889  2014 Immunohistochemical demonstration of transferrin receptor 1 and 2 in human hepatocellular carcinoma tissue. HCC
890  2014 In vivo molecular mapping of the tumor microenvironment in an azoxymethane-treated mouse model of colon carcinogenesis. AOM, EGFR, LIF, OCT, TGF-beta1
891  2014 Increased brain penetration and potency of a therapeutic antibody using a monovalent molecular shuttle. BBB
892  2014 Inhibition of monocyte adhesion to brain-derived endothelial cells by dual functional RNA chimeras. ICAM-1, OGD/R
893  2014 Iron stores of breastfed infants during the first year of life. PF
894  2014 Iron supplementation in young iron-deficient females causes gastrointestinal redox imbalance: protective effect of a fermented nutraceutical. GPx, MDA, SOD
895  2014 KLRG1 activity is regulated by association with the transferrin receptor. KLRG1
896  2014 Lentiviral Nef suppresses iron uptake in a strain specific manner through inhibition of Transferrin endocytosis. ---
897  2014 Micronutrient deficiencies are common in 6- to 8-year-old children of rural Nepal, with prevalence estimates modestly affected by inflammation. PLP
898  2014 MicroRNA miR-320a and miR-140 inhibit mink enteritis virus infection by repression of its receptor, feline transferrin receptor. MEV, miRNAs, nt, UTR
899  2014 Permeability of PEGylated immunoarsonoliposomes through in vitro blood brain barrier-medulloblastoma co-culture models for brain tumor therapy. ARL, BBB
900  2014 pH-controllable drug carrier with SERS activity for targeting cancer cells. DOX, SERS, Tf
901  2014 Phagolysosomal Trafficking Assay. BCG, MFI, Mtb, Rab5
902  2014 Preclinical evaluation of ⁸⁹Zr-labeled human antitransferrin receptor monoclonal antibody as a PET probe using a pancreatic cancer mouse model. ---
903  2014 Rab17-mediated recycling endosomes contribute to autophagosome formation in response to Group A Streptococcus invasion. GAS, GcAVs, REs
904  2014 Rab5 activity regulates GLUT4 sorting into insulin-responsive and non-insulin-responsive endosomal compartments: a potential mechanism for development of insulin resistance. CHI, GLUT4
905  2014 Regulatory effect of iron regulatory protein-2 on iron metabolism in lung cancer. ASODN, Fn, IRP2, Tf
906  2014 Role of ARF6, Rab11 and external Hsp90 in the trafficking and recycling of recombinant-soluble Neisseria meningitidis adhesin A (rNadA) in human epithelial cells. NadA, rNadA, rNadA
907  2014 Specific recycling receptors are targeted to the immune synapse by the intraflagellar transport system. APC, IFT, IFT20KD, MHC, TCR
908  2014 The Megalobrama amblycephala transferrin and transferrin receptor genes: molecular cloning, characterization and expression during early development and after Aeromonas hydrophila infection. Tf
909  2014 Therapeutic bispecific antibodies cross the blood-brain barrier in nonhuman primates. BBB
910  2014 Transferrin conjugated poly (gamma-glutamic acid-maleimide-co-L-lactide)-1,2-dipalmitoylsn-glycero-3-phosphoethanolamine copolymer nanoparticles for targeting drug delivery. HeLa, NPs, PTX, Tf
911  2014 Transferrin receptor (TfR) trafficking determines brain uptake of TfR antibody affinity variants. BBB
912  2014 Transferrin receptor-targeted theranostic gold nanoparticles for photosensitizer delivery in brain tumors. BBB
913  2014 Transferrin' activation: bonding with transferrin receptors tunes KLRG1 function. ITIM
914  2014 Trypanosoma brucei gambiense adaptation to different mammalian sera is associated with VSG expression site plasticity. ACLs, ESAGs, Tf, VSGs
915  2015 Antiretroviral Treatment Is Associated With Iron Deficiency in HIV-Infected Malawian Women That Is Mitigated With Supplementation, but Is Not Associated With Infant Iron Deficiency During 24 Weeks of Exclusive Breastfeeding. ARV, Hb, LNS
916  2015 Assessing potential peptide targeting ligands by quantification of cellular adhesion of model nanoparticles under flow conditions. ---
917  2015 Bionano interactions of mcf-7 breast tumor cells with a transferrin receptor targeted nanoparticle. ---
918  2015 Cellular localization of iron(II) polypyridyl complexes determines their anticancer action mechanisms. ---
919  2015 Characterisation of hepcidin response to holotransferrin treatment in CHO TRVb-1 cells. ---
920  2015 Combination of sequence-defined oligoaminoamides with transferrin-polycation conjugates for receptor-targeted gene delivery. Tf
921  2015 Development of synthetic of peptide-functionalized liposome for enhanced targeted ovarian carcinoma therapy. ---
922  2015 Development of synthetic of peptide-functionalized liposome for enhanced targeted ovarian carcinoma therapy. ---
923  2015 Dihydroartemisinin and transferrin dual-dressed nano-graphene oxide for a pH-triggered chemotherapy. DHA, GO, ROS, Tf
924  2015 Discovery and characterization of a novel non-competitive inhibitor of the divalent metal transporter DMT1/SLC11A2. hDMT1
925  2015 Effect of daily supplementation with iron and zinc on iron status of childbearing age women. Hb, IDA, SF, Zn
926  2015 Effects of developmental exposure to manganese and/or low iron diet: Changes to metal transporters, sucrose preference, elevated zero-maze, open-field, and locomotion in response to fenfluramine, amphetamine, and MK-801. DMT1, MnOE, Tf, VEH
927  2015 Endocytosis of a functionally enhanced GFP-tagged transferrin receptor in CHO cells. EGFP
928  2015 Endosomal Na+/H+ exchanger NHE5 influences MET recycling and cell migration. ---
929  2015 Engineering an Anti-Transferrin Receptor ScFv for pH-Sensitive Binding Leads to Increased Intracellular Accumulation. ---
930  2015 Enhanced anti-ischemic stroke of ZL006 by T7-conjugated PEGylated liposomes drug delivery system. BBB, BCECs, T7-P-LPs
931  2015 Enhancing Glioblastoma-Specific Penetration by Functionalization of Nanoparticles with an Iron-Mimic Peptide Targeting Transferrin/Transferrin Receptor Complex. BBB, DDS, GBM, Tf, Tf-NP
932  2015 Evaluation of Efficacy of Radioimmunotherapy with 90Y-Labeled Fully Human Anti-Transferrin Receptor Monoclonal Antibody in Pancreatic Cancer Mouse Models. RIT
933  2015 Expression of RNAs Coding for Metal Transporters in Blood of Patients with Huntington's Disease. Cd, DMT1, HD, Mn, Tf
934  2015 Expression of transferrin in hematoma brain tissue at different stages after intra cerebral hemorrhage in rats. ICH, Tf
935  2015 H-Ferritin Is Preferentially Incorporated by Human Erythroid Cells through Transferrin Receptor 1 in a Threshold-Dependent Manner. ---
936  2015 IGFBP-3/transferrin/transferrin receptor 1 complexes as principal mediators of IGFBP-3 delivery to colon cells in non-cancer and cancer tissues. CRC
937  2015 Intracellular Uropathogenic E. coli Exploits Host Rab35 for Iron Acquisition and Survival within Urinary Bladder Cells. BEC, UCV, UPEC, UTIs
938  2015 Intranasal deferoxamine attenuates synapse loss via up-regulating the P38/HIF-1alpha pathway on the brain of APP/PS1 transgenic mice. BDNF, DFO, DMT1, HIF-1alpha, MAPK, ROS
939  2015 Involvement of SARA in Axon and Dendrite Growth. SARA
940  2015 Iron homeostasis and its disruption in mouse lung in iron deficiency and overload. DMT1, FPN, ZIP14
941  2015 Iron Status Is Associated with Performance on Executive Functioning Tasks in Nonanemic Young Women. EF, ID, RT, TBI, TSAT, WRA
942  2015 Key role of phosphodiesterase 4A (PDE4A) in autophagy triggered by yessotoxin. LC3B, mTOR, PDE4A, YTX
943  2015 PEG-b-AGE Polymer Coated Magnetic Nanoparticle Probes with Facile Functionalization and Anti-fouling Properties for Reducing Non-specific Uptake and Improving Biomarker Targeting. IONPs, MPS, MRI, RES, Tf
944  2015 Retargeting of microcell fusion towards recipient cell-oriented transfer of human artificial chromosome. HAC, MMCT, MV, PEG
945  2015 Ruthenium polypyridyl complex inhibits growth and metastasis of breast cancer cells by suppressing FAK signaling with enhancement of TRAIL-induced apoptosis. ---
946  2015 Single Mutations in the VP2 300 Loop Region of the Three-Fold Spike of the Carnivore Parvovirus Capsid Can Determine Host Range. CPV
947  2015 The Effect of Baicalin as A PPAR Activator on Erythroid Differentiation of CD133(+)Hematopoietic Stem Cells in Umbilical Cord Blood. GPA, HSCs, PPARs
948  2015 Trafficking of Gold Nanoparticles Coated with the 8D3 Anti-Transferrin Receptor Antibody at the Mouse Blood-Brain Barrier. AuNPs, BBB
949  2015 [Testing the influence of lipid laden and iron-overloading on ceruloplasmin expression in RAW 264.7 cells]. Cp, DFO, FAC, FPN1, Ft, LPS, ox-LDL
950  2016 Alpha-synuclein modulates retinal iron homeostasis by facilitating the uptake of transferrin-bound iron: Implications for visual manifestations of Parkinson's disease. CREs, NTBI, PD, RPE, Tf
951  2016 An epirubicin-peptide conjugate with anticancer activity is dependent upon the expression level of the surface transferrin receptor. EPI, Tf
952  2016 Biodegradable Eri silk nanoparticles as a delivery vehicle for bovine lactoferrin against MDA-MB-231 and MCF-7 breast cancer cells. Apo-bLf, EGFR, NPs
953  2016 Combination of Curcumin with an Anti-Transferrin Receptor Antibody Suppressed the Growth of Malignant Gliomas In vitro. mAb
954  2016 Cross-sectional study of expression of divalent metal transporter-1, transferrin, and hepcidin in blood of smelters who are occupationally exposed to manganese. DMT1, Mn, Tf
955  2016 Deferoxamine-mediated up-regulation of HIF-1alpha prevents dopaminergic neuronal death via the activation of MAPK family proteins in MPTP-treated mice. DFO, ERK, GAP43, JNK, MAPK, MPTP, PD, SN, TH, VEGF
956  2016 Development of Core-Shell Nanostructures by In Situ Assembly of Pyridine-Grafted Diblock Copolymer and Transferrin for Drug Delivery Applications. CSNPs, DOX, P4VP, Tf
957  2016 DNA-based probes for flow cytometry analysis of endocytosis and recycling. SHIP, Tf
958  2016 Dual Functional Peptide-Driven Nanoparticles for Highly Efficient Glioma-Targeting and Drug Codelivery. BBB, DOX, RNAi
959  2016 Dual-targeting hybrid peptide-conjugated doxorubicin for drug resistance reversal in breast cancer. ABC, DOX, ERK, P-gp
960  2016 Energetics of ligand-receptor binding affinity on endothelial cells: An in vitro model. BBB, HUVEC, ITC, Tf
961  2016 Identification and Characterization of MicroRNAs in the Liver of Blunt Snout Bream (Megalobrama amblycephala) Infected by Aeromonas hydrophila. GO, KEGG, miRNAs, poi, Tf
962  2016 Improving sensitivity and specificity of capturing and detecting targeted cancer cells with anti-biofouling polymer coated magnetic iron oxide nanoparticles. CTCs, IONPs, PEG-b-AGE, Tf
963  2016 Inhibition of cerebral vascular inflammation by brain endothelium-targeted oligodeoxynucleotide complex. i.v, ICAM-1, LPS, TNF-alpha
964  2016 Magnetic Resonance Imaging Revealed Splenic Targeting of Canine Parvovirus Capsid Protein VP2. CPV, GQD
965  2016 Mathematical PKPD and safety model of bispecific TfR/BACE1 antibodies for the optimization of antibody uptake in brain. BACE1, BBB, PK-PD
966  2016 Post-Transcriptional Regulation of the GASC1 Oncogene with Active Tumor-Targeted siRNA-Nanoparticles. BLBC, LMW-PEI, Tf
967  2016 Prospective Design of Anti-Transferrin Receptor Bispecific Antibodies for Optimal Delivery into the Human Brain. BBB, PD, PK-PD
968  2016 Rational Design of a Transferrin-Binding Peptide Sequence Tailored to Targeted Nanoparticle Internalization. QSAR
969  2016 Real-Time Specific Light-Up Sensing of Transferrin Receptor: Image-Guided Photodynamic Ablation of Cancer Cells through Controlled Cytomembrane Disintegration. AIE, CLSM
970  2016 Targeted Delivery of siRNA to Transferrin Receptor Overexpressing Tumor Cells via Peptide Modified Polyethylenimine. BPEI, EGFP, GAPDH, siRNA
971  2016 Targeted siRNA Delivery Using a Lipo-Oligoaminoamide Nanocore with an Influenza Peptide and Transferrin Shell. siRNA, Tf
972  2016 Tf-PEG-PLL-PLGA nanoparticles enhanced chemosensitivity for hypoxia-responsive tumor cells. DNR, HIF-1alpha, IC50, NPs, PEG, Tf
973  2016 The Next Generation Non-competitive Active Polyester Nanosystems for Transferrin Receptor-mediated Peroral Transport Utilizing Gambogic Acid as a Ligand. CsA, GA, NS, PLGA
974  2016 Theranostic Polyaminocarboxylate-Cyanine-Transferrin Conjugate for Anticancer Therapy and Near-Infrared Optical Imaging. NIR, Tf
975  2016 Transferrin Receptor Controls AMPA Receptor Trafficking Efficiency and Synaptic Plasticity. CNS, KO, LTP
976  2016 Ultrasound Microbubble Treatment Enhances Clathrin-Mediated Endocytosis and Fluid-Phase Uptake through Distinct Mechanisms. CME, USMB
977  2017 A bispecific Tribody PET radioligand for visualization of amyloid-beta protofibrils - a new concept for neuroimaging. BBB, PET, scFv, WT
978  2017 Aggregation-Induced Emission Probe for Specific Turn-On Quantification of Soluble Transferrin Receptor: An Important Disease Marker for Iron Deficiency Anemia and Kidney Diseases. AIE, HSPN, IDA, sTfR, TPE
979  2017 An extended model of vesicle fusion at the plasma membrane to estimate protein lateral diffusion from TIRF microscopy images. TIRFM
980  2017 Ankaferd Influences mRNA Expression of Iron-Regulated Genes During Iron-Deficiency Anemia. ABS, Ankrd37, FAC, IDA
981  2017 Bidirectional apical-basal traffic of the cation-independent mannose-6-phosphate receptor in brain endothelial cells. BECs
982  2017 Bivalent Brain Shuttle Increases Antibody Uptake by Monovalent Binding to the Transferrin Receptor. AD, BBB, scFv
983  2017 Blocking transferrin receptor inhibits the growth of lung adenocarcinoma cells in vitro. LAC
984  2017 Blood-Brain Barrier Penetrating Biologic TNF-alpha Inhibitor for Alzheimer's Disease. AD, BBB, mAb, TNF-alpha, TNFIs, TNFR
985  2017 Controlling transferrin receptor trafficking with GPI-valence in bloodstream stage African trypanosomes. GPI, VSG
986  2017 Development of antibody-modified chitosan nanoparticles for the targeted delivery of siRNA across the blood-brain barrier as a strategy for inhibiting HIV replication in astrocytes. Ab-CS-NPs, B2R, BBB, CSNPs, HIV, RNAi, siRNA
987  2017 Diurnal variations in iron concentrations and expression of genes involved in iron absorption and metabolism in pigs. DMT1
988  2017 Dual-modified liposome codelivery of doxorubicin and vincristine improve targeting and therapeutic efficacy of glioma. BBB, BTB, DOX, VCR, VEGFR2
989  2017 Fattigation-platform nanoparticles using apo-transferrin stearic acid as a core for receptor-oriented cancer targeting. DOX, FTIR, MALDI-TOF, NPs, SEM, TEM, Tf, TfS, TNBS
990  2017 In vivo evaluation of microglia activation by intracranial iron overload in central pain after spinal cord injury. CP, DFX, Fn, IRP, NF, SCI
991  2017 In Vivo MR Imaging of Dual MRI Reporter Genes and Deltex-1 Gene-modified Human Mesenchymal Stem Cells in the Treatment of Closed Penile Fracture. CPF, DTX1, Fth, hMSC, MRI, SMCs
992  2017 Iron Homeostasis in Tissues Is Affected during Persistent Chlamydia pneumoniae Infection in Mice. C. pneumoniae, FPN1, Zn
993  2017 Mitochondrial VDAC1-based peptides: Attacking oncogenic properties in glioblastoma. BBB, GBM, VDAC1
994  2017 Na+/H+ Exchanger 9 Regulates Iron Mobilization at the Blood-Brain Barrier in Response to Iron Starvation. BBB, HBMVECs
995  2017 Next Generation Precision-Polyesters Enabling Optimization of Ligand-Receptor Stoichiometry for Modular Drug Delivery. GA, P2Ns, PEG, PLA, PLGA, Tf
996  2017 Noninvasive 89Zr-Transferrin PET Shows Improved Tumor Targeting Compared with 18F-FDG PET in MYC-Overexpressing Human Triple-Negative Breast Cancer. BRD4, TNBC
997  2017 One-Step Facile Synthesis of Highly Magnetic and Surface Functionalized Iron Oxide Nanorods for Biomarker-Targeted Applications. IONPs, MRI, Tf
998  2017 Pharmacokinetics, biodistribution and brain retention of a bispecific antibody-based PET radioligand for imaging of amyloid-beta. BBB, mAbs, PET
999  2017 Pica is prevalent and strongly associated with iron deficiency among Hispanic pregnant women living in the United States. AGP
1000  2017 PLGA nanoparticles modified with a BBB-penetrating peptide co-delivering Abeta generation inhibitor and curcumin attenuate memory deficits and neuropathology in Alzheimer's disease mice. AD, BBB, PLGA, ROS, SOD
1001  2017 Prevalence of Iron Deficiency and Iron Deficiency Anemia in the Northern and Southern Provinces of Rwanda. CI, DHS, ID, IDA, SF
1002  2017 Reduction in Brain Heparan Sulfate with Systemic Administration of an IgG Trojan Horse-Sulfamidase Fusion Protein in the Mucopolysaccharidosis Type IIIA Mouse. BBB, GAGs, HS, mAb, MPS-IIIA, SGSH
1003  2017 Regulation of iron metabolism by hypoxia-inducible factors. DMT1, FPN1, HIFs, IRPs
1004  2017 Selective regulation of clathrin-mediated epidermal growth factor receptor signaling and endocytosis by phospholipase C and calcium. CCPs, EGFR, PKC, PLC-gamma1
1005  2017 Transferrin receptor-targeted pH-sensitive micellar system for diminution of drug resistance and targetable delivery in multidrug-resistant breast cancer. DOX, DSPE-PEG2000, MDR, PHIS-PEG2000
1006  2017 Transferrin-Copper Nanocluster-Doxorubicin Nanoparticles as Targeted Theranostic Cancer Nanodrug. CI, DLA, DOX, FRET, Tf, Tf-Cu NC-Dox NPs
1007  2017 Uptake of 111In-labeled fully human monoclonal antibody TSP-A18 reflects transferrin receptor expression in normal organs and tissues of mice. ---
1008  2017 Zebrafish: A Visual Model To Evaluate the Biofate of Transferrin Receptor-Targeted 7Peptide-Decorated Coumarin 6 Micelles. 7pep
1009  2017 [The Establishment and Identification of Stable CHO Cell Line with Canine Transferrin Receptor Expression]. CHO
1010  2018 A PET Imaging Strategy for Interrogating Target Engagement and Oncogene Status in Pancreatic Cancer. ERK, PDAC
1011  2018 A stabilized retro-inverso peptide ligand of transferrin receptor for enhanced liposome-based hepatocellular carcinoma-targeted drug delivery. SPR, Tf
1012  2018 Antibody affinity and valency impact brain uptake of transferrin receptor-targeted gold nanoparticles. BBB
1013  2018 Blood-Brain Barrier Transport, Plasma Pharmacokinetics, and Neuropathology Following Chronic Treatment of the Rhesus Monkey with a Brain Penetrating Humanized Monoclonal Antibody Against the Human Transferrin Receptor. BBB, CSF, mAb, TfR1
1014  2018 Brain Shuttle Antibody for Alzheimer's Disease with Attenuated Peripheral Effector Function due to an Inverted Binding Mode. BS-mAb, FcgammaR, FIRs, IgG1, mAbs
1015  2018 Cargo regulates clathrin-coated pit invagination via clathrin light chain phosphorylation. CCPs, CLCs, GPCRs
1016  2018 Cognitive Performance in Indian School-Going Adolescents Is Positively Affected by Consumption of Iron-Biofortified Pearl Millet: A 6-Month Randomized Controlled Efficacy Trial. ANT, BI, CFE, CRT, GNG, ppm, SRT
1017  2018 Continuous Change in Membrane and Membrane-Skeleton Organization During Development From Proerythroblast to Senescent Red Blood Cell. MVE, RBCs
1018  2018 Deregulated iron metabolism in bone marrow from adenine-induced mouse model of chronic kidney disease. BM, CKD, EPO
1019  2018 Dual-modified natural high density lipoprotein particles for systemic glioma-targeting drug delivery. BBB, BBTB, HCPT, HDL, VEGFR2
1020  2018 Dual-targeting biomimetic delivery for anti-glioma activity via remodeling the tumor microenvironment and directing macrophage-mediated immunotherapy. TAMs, TME
1021  2018 Effect of the volatile anesthetic agent isoflurane on lateral diffusion of cell membrane proteins. GPI, ISO
1022  2018 Efficient clearance of Abeta protofibrils in AbetaPP-transgenic mice treated with a brain-penetrating bifunctional antibody. AbetaPP, AD, ELISA, PET, RmAb158
1023  2018 Emerging Technologies for Delivery of Biotherapeutics and Gene Therapy Across the Blood-Brain Barrier. BBB, CNS, IR, RMT
1024  2018 Engineering oncolytic vaccinia virus with functional peptides through mild and universal strategy. azide-OVV, DBCO, OV, OVV
1025  2018 Enhanced blood-brain barrier penetration and glioma therapy mediated by T7 peptide-modified low-density lipoprotein particles. BBB, LDL, LDLR, VCR
1026  2018 Enhanced Delivery of Galanin Conjugates to the Brain through Bioengineering of the Anti-Transferrin Receptor Antibody OX26. BBB, CSF
1027  2018 Fabrication and evaluation of a γ-PGA-based self-assembly transferrin receptor-targeting anticancer drug carrier. CDDP, DLS, KM, PAMCP, PGA, TEM
1028  2018 High detection sensitivity with antibody-based PET radioligand for amyloid beta in brain. BBB
1029  2018 Intracellular sorting and transcytosis of the rat transferrin receptor antibody OX26 across the blood-brain barrier invitro is dependent on its binding affinity. BBB
1030  2018 Iron-mimic peptide converts transferrin from foe to friend for orally targeting insulin delivery. NPs, Tf
1031  2018 Lactoferrin ameliorates dopaminergic neurodegeneration and motor deficits in MPTP-treated mice. BDNF, CREB, ERK, HIF-1alpha, JNK, LF, MAPK, MPTP, PD
1032  2018 Mutant huntingtin induces iron overload via up-regulating IRP1 in Huntington's disease. HD, IRP1, Tf
1033  2018 Oral deferiprone administration ameliorates cisplatin-induced nephrotoxicity in rats. ---
1034  2018 Peptide T7-modified polypeptide with disulfide bonds for targeted delivery of plasmid DNA for gene therapy of prostate cancer. PCa, pDNA
1035  2018 Piezoelectric barium titanate nanostimulators for the treatment of glioblastoma multiforme. BTNPs
1036  2018 Polydopamine-based functional composite particles for tumor cell targeting and dual-mode cellular imaging. BSA, FL, GA, MB, PDA, SERS, Tf
1037  2018 Rab11 mediates selective recycling and endocytic trafficking in Trypanosoma brucei. GPI, VSG
1038  2018 Receptor mediated transcytosis in biological barrier: The influence of receptor character and their ligand density on the transmembrane pathway of active-targeting nanocarriers. ARE, CRE
1039  2018 Six-Transmembrane Epithelial Antigen of Prostate 3 Predicts Poor Prognosis and Promotes Glioblastoma Growth and Invasion. OS, Steap3
1040  2018 Subclinical inflammation affects iron and vitamin A but not zinc status assessment in Senegalese children and Cambodian children and women. APR, CF, FER, RBP
1041  2018 Transcytosis of payloads that are non-covalently complexed to bispecific antibodies across the hCMEC/D3 blood-brain barrier model. BBB, BsAbs
1042  2018 Transferrin-Modified Vitamin-E/Lipid Based Polymeric Micelles for Improved Tumor Targeting and Anticancer Effect of Curcumin. PEG
1043  2019 A Method for Targeted Nonviral siRNA Delivery in Cancer and Inflammatory Diseases. PEI, RNAi, siRNA, Tf
1044  2019 A new technology for increasing therapeutic protein levels in the brain over extended periods. BBB, MOG, RMT
1045  2019 Accurate measurement of fast endocytic recycling kinetics in real time. ---
1046  2019 Actively priming autophagic cell death with novel transferrin receptor-targeted nanomedicine for synergistic chemotherapy against breast cancer. ACD, PTX, RAP
1047  2019 Alterations in the Iron Homeostasis Network of Hepatocytes Caused by Hepatitis B Virus. ALT, CHB, HBV, HCs, SI, sTfR, TIBC, TRF, TS, UIBC
1048  2019 Bacterial magnetosomes loaded with doxorubicin and transferrin improve targeted therapy of hepatocellular carcinoma. DOX, Tf
1049  2019 Design, synthesis, and in vitro antitumor activity of a transferrin receptor-targeted peptide-doxorubicin conjugate. DOX, SMP
1050  2019 Development of Novel antimiRzymes for Targeted Inhibition of miR-21 Expression in Solid Cancer Cells. miR-21, miRNAs
1051  2019 Dihydroartemisinin and its anticancer activity against endometrial carcinoma and cervical cancer: involvement of apoptosis, autophagy and transferrin receptor. DHA, LC3
1052  2019 Discovery of An Orally Effective Factor IX-Transferrin Fusion Protein for Hemophilia B. FIX, Tf
1053  2019 Dynamic Imaging of Transferrin Receptor Molecules on Single Live Cell with Bridge Gaps-Enhanced Raman Tags. BGERTs, PEG, SERS, Tf
1054  2019 Effect of locally produced complementary foods on fat-free mass, linear growth, and iron status among Kenyan infants: A randomized controlled trial. FFM, WFC, WFL
1055  2019 Fabrication and evaluation a transferrin receptor targeting nano-drug carrier for cerebral infarction treatment. BBB, TEM
1056  2019 Holo-Lactoferrin Modified Liposome for Relieving Tumor Hypoxia and Enhancing Radiochemotherapy of Cancer. DOX, holo-Lf
1057  2019 Intestinal permeability and inflammation mediate the association between nutrient density of complementary foods and biochemical measures of micronutrient status in young children: results from the MAL-ED study. AAT, EED, LMZ, MPO, NEO
1058  2019 Iron Exposure and the Cellular Mechanisms Linked to Neuron Degeneration in Adult Mice. AD, DMT1, FPN, HDI, ROS, WT
1059  2019 Lesion of the Locus Coeruleus Damages Learning and Memory Performance in Paraquat and Maneb-induced Mouse Parkinson's Disease Model. FPN1, GPX4, LC, NE, PD
1060  2019 Local synthesis of hepcidin in the anterior segment of the eye: A novel observation with physiological and pathological implications. AH, CB, CE, Cp, FPN, LE, RT-PCR, TM
1061  2019 Low-toxicity transferrin-guided polymersomal doxorubicin for potent chemotherapy of orthotopic hepatocellular carcinoma in vivo. HCC, Lipo-Dox, Lipo-Dox, Tf, Tf-Ps-Dox, Tf-Ps-Dox
1062  2019 Meta-analysis of efficacy of iron and iodine fortified salt in improving iron nutrition status. CI, DFS, Hb, ID, IDA, IS
1063  2019 Metal bashing: iron deficiency and manganese overexposure impact on peripheral nerves. CNS, DMT1, MBP, Mn, PMP22, PNS
1064  2019 Method of establishing breast cancer brain metastases affects brain uptake and efficacy of targeted, therapeutic nanoparticles. IC, ICD
1065  2019 Modulating the antibody density changes the uptake and transport at the blood-brain barrier of both transferrin receptor-targeted gold nanoparticles and liposomal cargo. AuNPs, BBB, BCECs
1066  2019 Molecularly Distinct Clathrin-Coated Pits Differentially Impact EGFR Fate and Signaling. AP-2, CCPs, CME, EGFR
1067  2019 Nanoparticle-Modified Apoferritin Nanotransfer for Targeted Cytostatic Transport. APO, DOX, SDS-PAGE
1068  2019 Next-Generation Noncompetitive Nanosystems Based on Gambogic Acid: In silico Identification of Transferrin Receptor Binding Sites, Regulatory Shelf Stability, and Their Preliminary Safety in Healthy Rodents. GA
1069  2019 Nutritional status of Tajik children and women: Transition towards a double burden of malnutrition. Hb, RBP, SF
1070  2019 Prenatal Ethanol Exposure Misregulates Genes Involved in Iron Homeostasis Promoting a Maladaptation of Iron Dependent Hippocampal Synaptic Transmission and Plasticity. Ft, LTP, mRNA, PAE, PFC
1071  2019 Retrospective study of small pet tumors treated with Artemisia annua and iron. ---
1072  2019 Role of TfR2-Y250X and TfR1- rs3817672 Single Nucleotide Polymorphism on Pathophysiology of Iron Deficiency Anemia. TfR1, TfR2
1073  2019 Secretory IgA accumulated in the airspaces of idiopathic pulmonary fibrosis and promoted VEGF, TGF-beta and IL-8 production by A549 cells. IL, IPF, sIgA, TGF, VEGF
1074  2019 Targeting the transferrin receptor for brain drug delivery. BBB
1075  2019 The Impact of Perinatal Cobalt Chloride Exposure on Extramedullary Erythropoiesis, Tissue Iron Levels, and Transferrin Receptor Expression in Mice. MCH, MCV, TIBC
1076  2019 The Trypanosomal Transferrin Receptor of Trypanosoma Brucei-A Review. AT, HAT, Tf
1077  2019 Therapeutic Bispecific T-Cell Engager Antibody Targeting the Transferrin Receptor. BiTE
1078  2019 Transferrin receptor 1 overexpression is associated with tumour de-differentiation and acts as a potential prognostic indicator of hepatocellular carcinoma. AFP, FPN1, HCC
1079  2019 Transferrin receptor binds virus capsid with dynamic motion. CPV
1080  2019 Transferrin Receptor-Mediated Uptake at the Blood-Brain Barrier Is Not Impaired by Alzheimer's Disease Neuropathology. AD, BBB, BCECs
1081  2019 Transferrin-decorated thymoquinone-loaded PEG-PLGA nanoparticles exhibit anticarcinogenic effect in non-small cell lung carcinoma via the modulation of miR-34a and miR-16. miRNA, NSCLC, Tf, TQ-Np
1082  2019 Transport of the Ruthenium Complex [Ru(GA)(dppe)2]PF6 into Triple-Negative Breast Cancer Cells Is Facilitated by Transferrin Receptors. GA, Ru, TNBC
1083  2020 A TfR-Binding Cystine-Dense Peptide Promotes Blood-Brain Barrier Penetration of Bioactive Molecules. BBB, CDPs, CNS
1084  2020 An Affibody Molecule Is Actively Transported into the Cerebrospinal Fluid via Binding to the Transferrin Receptor. CNS
1085  2020 Association of transferrin G258A and transferrin receptor A82G polymorphisms with the risk of Parkinson disease in certain area. ORs, PD, Tf
1086  2020 BBB-penetrating codelivery liposomes treat brain metastasis of non-small cell lung cancer with EGFRT790M mutation. BBB, BMs, NSCLC, TAM
1087  2020 Brain-targeted delivery of obidoxime, using aptamer-modified liposomes, for detoxification of organophosphorus compounds. AChE, Apt-LP, BBB, dT, OPs, POX
1088  2020 Chronic inflammation was a major predictor and determinant factor of anemia in lactating women in Sidama zone southern Ethiopia: A cross-sectional study. AGP, Hb
1089  2020 Complex Rab4-Mediated Regulation of Endosomal Size and EGFR Activation. EGFR-p1068
1090  2020 Differential expression of receptors mediating receptor-mediated transcytosis (RMT) in brain microvessels, brain parenchyma and peripheral tissues of the mouse and the human. BBB, IGF1R, INSR, LEPR, RMT
1091  2020 Dual-Effect of Magnetic Resonance Imaging Reporter Gene in Diagnosis and Treatment of Hepatocellular Carcinoma. AFP, FTH, HCC, T2WI, Tf-LP
1092  2020 Enhanced in Vivo Blood-Brain Barrier Penetration by Circular Tau-Transferrin Receptor Bifunctional Aptamer for Tauopathy Therapy. BBB, TBI
1093  2020 Establishment of a hTfR mAb-functionalized HPPS theranostic nanoplatform. mAb
1094  2020 Fluorine-18-Labeled Antibody Ligands for PET Imaging of Amyloid-beta in Brain. BBB, TCO
1095  2020 Human induced pluripotent stem cells (BIONi010-C) generate tight cell monolayers with blood-brain barrier traits and functional expression of large neutral amino acid transporter 1 (SLC7A5). BBB, BCEC, hiPSC, LRP1, SLC's, TEER
1096  2020 Impact of early-onset persistent stunting on cognitive development at 5 years of age: Results from a multi-country cohort study. LMICs, WPPSI
1097  2020 Interactions between iron and manganese in neurotoxicity. Mn
1098  2020 Iron Chelation Properties of Green Tea Epigallocatechin-3-Gallate (EGCG) in Colorectal Cancer Cells: Analysis on Tfr/Fth Regulations and Molecular Docking. CRC, EGCG, FtH
1099  2020 Iron transport across the human placenta is regulated by hepcidin. ---
1100  2020 Muscone/RI7217 co-modified upward messenger DTX liposomes enhanced permeability of blood-brain barrier and targeting glioma. BBB, CLSM, DTX, TCM
1101  2020 NIR Photodynamic Destruction of PDAC and HNSCC Nodules Using Triple-Receptor-Targeted Photoimmuno-Nanoconjugates: Targeting Heterogeneity in Cancer. Cet-PINs, EGFR, HER2, PDAC, PDT, TR-PIN
1102  2020 Novel nanopolymer RNA therapeutics normalize human diabetic corneal wound healing and epithelial stem cells. AON, LECs
1103  2020 Potential Mechanisms Underlying the Hepatic-Protective Effects of Danshensu on Iron Overload Mice. DMT1, GSH-Px, IL-6, SOD, TGF-beta
1104  2020 Probing and Enhancing Ligand-Mediated Active Targeting of Tumors Using Sub-5 nm Ultrafine Iron Oxide Nanoparticles. EPR, NP, Tf, uIONPs
1105  2020 Quantitative label-free imaging of iron-bound transferrin in breast cancer cells and tumors. Tf
1106  2020 Regulation of the Transferrin Receptor Recycling in Hepatitis C Virus-Replicating Cells. HCV
1107  2020 Selection for Anti-transferrin Receptor Bispecific T-cell Engager in Different Molecular Formats. BiTE, BsAb, scFvs
1108  2020 Smart Strategies for Therapeutic Agent Delivery into Brain across the Blood-Brain Barrier Using Receptor-Mediated Transcytosis. BBB, CNS, CPPs, INSR, LDLR, mAbs, RMT
1109  2020 Steric constraints control processing of glycosylphosphatidylinositol anchors in Trypanosoma brucei. BSF, ESAG6 or E6, GPI, TL
1110  2020 Tetravalent Bispecific Tandem Antibodies Improve Brain Exposure and Efficacy in an Amyloid Transgenic Mouse Model. APP, BBB, IgGs, Tg
1111  2020 The development of lentil derived protein-iron complexes and their effects on iron deficiency anemia in vitro. ANKRD37, DMT1, GI, IDA
1112  2020 The Prevalence of Insomnia and the Link between Iron Metabolism Genes Polymorphisms, TF rs1049296 C>T, TF rs3811647 G>A, TFR rs7385804 A>C, HAMP rs10421768 A>G and Sleep Disorders in Polish Individuals with ASD. AIS, ASD, HAMP, SNPs, TF
1113  2020 The Role of Insulin Regulated Aminopeptidase in Endocytic Trafficking and Receptor Signaling in Immune Cells. IRAP
1114  2020 Transferrin-binding peptide functionalized polymersomes mediate targeted doxorubicin delivery to colorectal cancer in vivo. DOX, Tf
1115  2020 Variability in the cleavage of exosome-associated transferrin receptor questions the utility of clinically useful soluble transferrin receptor assays for dogs, cats, and horses. sTfR
1116  2020 Zoledronic Acid Abrogates Restraint Stress-Induced Macrophage Infiltration, PDGF-AA Expression, and Ovarian Cancer Growth. GM-CSF, IL-5, MIF, PDGF-AA, VEGF
1117  2021 A DNA Aptameric Ligand of Human Transferrin Receptor Generated by Cell-SELEX. ---
1118  2021 A Multifunctional AIE Nanoprobe as a Drug Delivery Bioimaging and Cancer Treatment System. AIE, BBB, BTB
1119  2021 Activation of vitamin D receptor inhibits Tau phosphorylation is associated with reduction of iron accumulation in APP/PS1 transgenic mice. AD, BACE1, IRP2, PAL, VDR
1120  2021 Brain pharmacokinetics of anti-transferrin receptor antibody affinity variants in rats determined using microdialysis. BCECs, bISF, CNS, mAb, PK, RMT
1121  2021 Brain-targeting delivery of MMB4 DMS using carrier-free nanomedicine CRT-MMB4@MDZ. CRT, MDZ, MMB4 DMS, MMB4-NC, Tf
1122  2021 Chitosan-based nanoparticle co-delivery of docetaxel and curcumin ameliorates anti-tumor chemoimmunotherapy in lung cancer. CBT-DC, CMCS, CUR, DTX, ROS
1123  2021 Clofazimine functionalized polymeric nanoparticles for brain delivery in the tuberculosis treatment. BBB, CFZ, CNS TB, NPs, PEG, PLGA
1124  2021 Comparison of polypeptides that bind the transferrin receptor for targeting gold nanocarriers. ---
1125  2021 Comparison of three synthetic transferrin mimetic small peptides to promote the blood-brain barrier penetration of vincristine liposomes for improved glioma targeted therapy. BBB, T7-LS, VCR
1126  2021 Effect of atrazine on accumulation of iron via the iron transport proteins in the midbrain of SD rats. ATR, DMT1, FPN1, Heph, TH
1127  2021 Embryotoxicity of silver nanomaterials (Ag NM300k) in the soil invertebrate Enchytraeus crypticus - Functional assay detects Ca channels shutdown. Ca, FLC, LTCC, NM
1128  2021 Evaluating the single-molecule interactions between targeted peptides and the receptors on living cell membrane. AFM, DDSs, EGFR, Kon, SMFS
1129  2021 Experimental modulation of Interleukin 1 shows its key role in chronic kidney disease progression and anemia. CKD, EPO, EPOR, HIF2, IL-1, RaKO
1130  2021 Ferrostatin-1 alleviates lipopolysaccharide-induced cardiac dysfunction. Fer-1, FTL, GPX4, IkappaBalpha, IL-6, LPS, NF-kappaB, PTGS2, TLR4
1131  2021 Immunochemical analysis of iron transporters and M2 macrophages in ovarian endometrioma and clear cell adenocarcinoma. CCC, DMT1, EAOC, FPN, OE, TAMs
1132  2021 Iron induces two distinct Ca2+ signalling cascades in astrocytes. DMT1, Tf
1133  2021 Mathematical Models of Blood-Brain Barrier Transport of Monoclonal Antibodies Targeting the Transferrin Receptor and the Insulin Receptor. BBB, IR, mAb, RMT, Tf
1134  2021 Multifunctional PLGA nanoparticles combining transferrin-targetability and pH-stimuli sensitivity enhanced doxorubicin intracellular delivery and in vitro antineoplastic activity in MDR tumor cells. MDR
1135  2021 Nonclinical safety evaluation of pabinafusp alfa, an anti-human transferrin receptor antibody and iduronate-2-sulfatase fusion protein, for the treatment of neuronopathic mucopolysaccharidosis type II. ---
1136  2021 Peptide-Functionalized Nanoparticles-Encapsulated Cyclin-Dependent Kinases Inhibitor Seliciclib in Transferrin Receptor Overexpressed Cancer Cells. CDKs, NPs, PLGA
1137  2021 Phosphorylation of REPS1 at Ser709 by RSK attenuates the recycling of transferrin receptor. EGF, EGFR, KO, MEK, REPS1, REPS1
1138  2021 Piperine-Loaded Glycyrrhizic Acid- and PLGA-Based Nanoparticles Modified with Transferrin for Antitumor : Piperine-Loaded Glycyrrhizic Acid- and PLGA-Based Nanoparticles. GL
1139  2021 Rab7-harboring vesicles are carriers of the transferrin receptor through the biosynthetic secretory pathway. RUSH
1140  2021 Revealing the Dynamic Mechanism by Which Transferrin Promotes the Cellular Uptake of HAIYPRH Peptide-Conjugated Nanostructures by Force Tracing. AFM, Tf
1141  2021 The iron chelator, PBT434, modulates transcellular iron trafficking in brain microvascular endothelial cells. Cp, HBMVEC
1142  2021 The Transferrin Receptor-Directed CAR for the Therapy of Hematologic Malignancies. CAR
1143  2022 2D-ultrathin MXene/DOXjade platform for iron chelation chemo-photothermal therapy. DOX
1144  2022 A Brain-Targeting Bispecific-Multivalent Antibody Clears Soluble Amyloid-Beta Aggregates in Alzheimer's Disease Mice. AD, scFv
1145  2022 Altered blood-brain barrier transport of nanotherapeutics in lysosomal storage diseases. BBB, CAM, LSDs, NCs, NPD
1146  2022 Brain Cancer Chemotherapy through a Delivery System across the Blood-Brain Barrier into the Brain Based on Receptor-Mediated Transcytosis Using Monoclonal Antibody Conjugates. Ab, ADCs, BBB, CNS, INSR, MDR1, RMT
1147  2022 Brain microvascular endothelial cells derived from human induced pluripotent stem cells as in vitro model for assessing blood-brain barrier transferrin receptor-mediated transcytosis. BBB, BMEC, HBEC, hiPS-BMEC, RMT
1148  2022 Development of a three-dimensional blood-brain barrier network with opening capillary structures for drug transport screening assays. BBB, BMEC, Pe
1149  2022 Discovery and engineering of an anti-TREM2 antibody to promote amyloid plaque clearance by microglia in 5XFAD mice. AD, oAbeta, TREM2, TVD-Ig
1150  2022 Enhanced anti-angiogenetic effect of transferrin receptor-mediated delivery of VEGF-trap in a glioblastoma mouse model. BBB, GBM, Tf, VEGF
1151  2022 G-Quadruplex-Proximized Aptamers (G4PA) Efficiently Targeting Cell-Surface Transferrin Receptors for Targeted Cargo Delivery. ---
1152  2022 Hepatic TGFβr1 Deficiency Attenuates Lipopolysaccharide/D-Galactosamine-Induced Acute Liver Failure Through Inhibiting GSK3β-Nrf2-Mediated Hepatocyte Apoptosis and Ferroptosis. ALF, CHAC1, D-GalN, DFOM, Fer-1, FSP1, GPX4, LPS
1153  2022 Hepcidin regulates neuronal ferroptosis: A mechanism for postoperative cognitive dysfunction. GPX4, HEPC, MD-2, MDA, POCD, SOD, Tg, TLR4, WT
1154  2022 Human Immortalized Cell-Based Blood-Brain Barrier Spheroid Models Offer an Evaluation Tool for the Brain Penetration Properties of Macromolecules. BBB, RMT
1155  2022 IgG Fusion Proteins for Brain Delivery of Biologics via Blood-Brain Barrier Receptor-Mediated Transport. BBB, HIR, mAb
1156  2022 In vivo imaging of alpha-synuclein with antibody-based PET. alpha-Syn, MSA, PD, PET
1157  2022 Intraductal administration of transferrin receptor-targeted immunotoxin clears ductal carcinoma in situ in mouse models of breast cancer-a preclinical study. DCIS, i.duc, IT, IVIS, MIND, PE
1158  2022 Iron overload in alcoholic liver disease: underlying mechanisms, detrimental effects, and potential therapeutic targets. ALD, EPO, HSCs, KCs
1159  2022 Kinetics of Blood-Brain Barrier Transport of Monoclonal Antibodies Targeting the Insulin Receptor and the Transferrin Receptor. BBB, IR, mAb
1160  2022 Local iron deficiency in the substantia nigra directly contributes to hyperlocomotion phenotypes. DFP, SN
1161  2022 Molecular architecture determines brain delivery of a transferrin receptor-targeted lysosomal enzyme. BBB, ETV, IDS, MPS II
1162  2022 Passive and receptor mediated brain delivery of an anti-GFAP nanobody. GFAP, scFv8D3, WT
1163  2022 Roots of Astragalus propinquus Schischkin Regulate Transmembrane Iron Transport and Ferroptosis to Improve Cerebral Ischemia-Reperfusion Injury. CIRI, DMT1, FHC, FLC, Fn, FPN1, GPX4, HO-1, IHC, IREB2, LTCC, MCAO, Nrf2, RAP, Tf, TRPC6, TTC
1164  2022 Signature Effects of Vector-Guided Systemic Nano Bioconjugate Delivery Across Blood-Brain Barrier of Normal, Alzheimer's, and Tumor Mouse Models. AD, AP2, BBB, CNS, LRP-1
1165  2022 Strategies for Targeted Delivery of Exosomes to the Brain: Advantages and Challenges. BBB, CNS, INSR, LDLR, RMT
1166  2022 Targeted Delivery of Doxorubicin Using Transferrin-Conjugated Carbon Dots for Cancer Therapy. CHO, GCD
1167  2022 TfR Aptamer Enhanced Blood-Brain Barrier Penetration of Biomimetic Nanocomplexes for Intracellular Transglutaminase 2 Imaging and Silencing in Glioma. BBB, GBM, TG2
1168  2022 The effect of iron dextran on vitamin D3 metabolism in SD rats. DFe, Hb, IDA, RBC, SI, Tf, TIBC, VD
1169  2022 The Immune-Specific E3 Ubiquitin Ligase MARCH1 Is Upregulated during Human Cytomegalovirus Infection to Regulate Iron Levels. HCMV
1170  2022 Towards a translational physiologically-based pharmacokinetic (PBPK) model for receptor-mediated transcytosis of anti-transferrin receptor monoclonal antibodies in the central nervous system. CNS, CSF, ISF, mAbs, PBPK, RMT
1171  2022 Transferrin receptor-mediated liposomal drug delivery: recent trends in targeted therapy of cancer. ---
1172  2022 Transferrin Receptor-Targeted Nanocarriers: Overcoming Barriers to Treat Glioblastoma. BBB, DDS, GBM, NPs, Tf
1173  2022 Transferrin/folate dual-targeting Pluronic F127/poly(lactic acid) polymersomes for effective anticancer drug delivery. FR, Ps, PTX
1174  2022 α-Lipoic Acid-Plus Ameliorates Endothelial Injury by Inhibiting the Apoptosis Pathway Mediated by Intralysosomal Cathepsins in an In Vivo and In Vitro Endothelial Injury Model. AO, CAII, DFO, HUVECs, LAP, oxyHb