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Abbreviation: 4-HNE
Appearance Frequency: 1515 time(s)
Long forms: 16

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Long Form No. Long Form Research Area Co-occurring Abbreviation PubMed/MEDLINE Info. (Year, Title)
4-hydroxynonenal
(1449 times)
Biochemistry
(266 times)
MDA (299 times)
ROS (203 times)
SOD (89 times)
1986 4-Hydroxynonenal and other aldehydes produced in the liver in vivo after bromobenzene intoxication.
4-hydroxy-trans-2-nonenal
(28 times)
Biochemistry
(7 times)
MDA (5 times)
ROS (5 times)
ALDH2 (4 times)
1990 The levels of quinone reductases, superoxide dismutase and glutathione-related enzymatic activities in diethylstilbestrol-induced carcinogenesis in the kidney of male Syrian golden hamsters.
4-hydroxynon-2-enal
(17 times)
Biochemistry
(7 times)
4ONE (4 times)
GST (4 times)
1HNO (2 times)
1999 Crystal structure of a murine glutathione S-transferase in complex with a glutathione conjugate of 4-hydroxynon-2-enal in one subunit and glutathione in the other: evidence of signaling across the dimer interface.
4 hydroxy-2-nonenal adducts
(4 times)
Geriatrics
(2 times)
BDL (1 time)
BMI (1 time)
Cer (1 time)
2006 Heat shock protein 60 response to exercise in diabetes: effects of alpha-lipoic acid supplementation.
4-hydroxy-trans-2,3-nonenal
(3 times)
Biochemistry
(2 times)
4-HHE (1 time)
ERRgamma (1 time)
HNE-SG (1 time)
1999 Glutathione conjugation of 4-hydroxy-trans-2,3-nonenal in the rat in vivo, the isolated perfused liver and erythrocytes.
4-hydroxynonenal protein adducts
(3 times)
Diabetes Mellitus
(1 time)
8-IsoP (1 time)
Bcl-2 (1 time)
G6PDH (1 time)
2008 Involvement of oxidative stress and caspase 2-mediated intrinsic pathway signaling in age-related increase in muscle cell apoptosis in mice.
4-hydroxy-nonenal-histidine
(2 times)
Geriatrics
(1 time)
3-NT (2 times)
4-AP (1 time)
ACh (1 time)
2013 Age- and diabetes-induced regulation of oxidative protein modification in rat brain and peripheral tissues: consequences of treatment with antioxidant pyridoindole.
4-HNE-protein
(1 time)
--- 2022 Oxidative Stress and 4-hydroxy-2-nonenal (4-HNE): Implications in the Pathogenesis and Treatment of Aging-related Diseases.
4-HNE100S
(1 time)
Biology
(1 time)
APD (1 time)
GPVMs (1 time)
hERG (1 time)
2018 Suppression of hERG K+ current and cardiac action potential prolongation by 4-hydroxynonenal via dual mechanisms.
10  4-HNE10L
(1 time)
Biology
(1 time)
APD (1 time)
GPVMs (1 time)
hERG (1 time)
2018 Suppression of hERG K+ current and cardiac action potential prolongation by 4-hydroxynonenal via dual mechanisms.
11  4-hydroxy-2-nonenal histidine adduct
(1 time)
Urology
(1 time)
--- 2011 Antioxidant therapy alleviates oxidative stress by androgen deprivation and prevents conversion from androgen dependent to castration resistant prostate cancer.
12  4-hydroxy-2-nonenal-modified protein
(1 time)
Neurology
(1 time)
MyD (1 time)
NFT (1 time)
2006 Neurofibrillary tangles and deposition of oxidative products in the brain in cases of myotonic dystrophy.
13  4-hydroxynonenoic acid
(1 time)
General Surgery
(1 time)
CAT (1 time)
ELISA (1 time)
GSH-Px (1 time)
2023 Naringenin attenuates cerebral ischemia/reperfusion injury by inhibiting oxidative stress and inflammatory response via the activation of SIRT1/FOXO1 signaling pathway in vitro.
14  hematoxylin-eosin (H&E) staining, 4-hydroxynonenal
(1 time)
Toxicology
(1 time)
ATF3 (1 time)
ATF4 (1 time)
eIF2alpha (1 time)
2023 Toosendanin induced hepatotoxicity via triggering PERK-eIF2α-ATF4 mediated ferroptosis.
15  high expression of 4-hydroxynonenal
(1 time)
Medicine
(1 time)
GFAP (1 time)
2020 Lipid Peroxidation Induces Reactive Astrogliosis by Activating WNT/beta-Catenin Pathway in Hydrocephalus.
16  hippocampal expression of 4-hydroneonenal
(1 time)
Pharmacology
(1 time)
HO-1 (1 time)
iNOS (1 time)
PTZ (1 time)
2018 Neuroprotective mechanisms of sildenafil and selenium in PTZ-kindling model: Implications in epilepsy.