| 1 |
AMP-activated protein kinase
(8489 times)
|
Biochemistry
(1540 times)
|
mTOR (562 times)
AICAR (518 times)
ACC (508 times)
|
1992 Insulin activation of acetyl-CoA carboxylase accompanied by inhibition of the 5'-AMP-activated protein kinase.
|
| 2 |
adenosine monophosphate-activated protein kinase
(2100 times)
|
Biochemistry
(221 times)
|
mTOR (222 times)
ROS (129 times)
ACC (88 times)
|
1997 Insulin inhibition of 5' adenosine monophosphate-activated protein kinase in the heart results in activation of acetyl coenzyme A carboxylase and inhibition of fatty acid oxidation.
|
| 3 |
AMP-activated kinase
(380 times)
|
Biochemistry
(67 times)
|
AICAR (27 times)
mTOR (22 times)
ROS (17 times)
|
1999 AMP-activated kinase reciprocally regulates triacylglycerol synthesis and fatty acid oxidation in liver and muscle: evidence that sn-glycerol-3-phosphate acyltransferase is a novel target.
|
| 4 |
AMP kinase
(160 times)
|
Biochemistry
(28 times)
|
AICAR (15 times)
mTOR (11 times)
NO (8 times)
|
2001 Activation of AMP kinase enhances sensitivity of muscle glucose transport to insulin.
|
| 5 |
AMP-dependent protein kinase
(113 times)
|
Cell Biology
(21 times)
|
mTOR (7 times)
ROS (7 times)
AICAR (5 times)
|
1996 Increased cardiac fatty acid uptake with dobutamine infusion in swine is accompanied by a decrease in malonyl CoA levels.
|
| 6 |
AMP-dependent kinase
(63 times)
|
Cell Biology
(9 times)
|
ROS (8 times)
mTOR (7 times)
AICAR (5 times)
|
2004 Mechanisms underlying the impaired regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in aged rat liver.
|
| 7 |
adenosine monophosphate kinase
(57 times)
|
Biochemistry
(10 times)
|
mTOR (8 times)
LKB1 (4 times)
ACC (3 times)
|
2004 Adiponectin, obesity, and cardiovascular disease.
|
| 8 |
AMP protein kinase
(23 times)
|
Biochemistry
(5 times)
|
AICAR (3 times)
ROS (3 times)
eNOS (2 times)
|
2000 Increased expression of GLUT-4 and hexokinase in rat epitrochlearis muscles exposed to AICAR in vitro.
|
| 9 |
monophosphate-activated kinase
(10 times)
|
Cell Biology
(2 times)
|
LKB1 (2 times)
ADT (1 time)
CAIA (1 time)
|
2010 Palmitate induces C-reactive protein expression in human aortic endothelial cells. Relevance to fatty acid-induced endothelial dysfunction.
|
| 10 |
AMP-activated serine/threonine protein kinase
(5 times)
|
Physiology
(3 times)
|
mTOR (2 times)
LKB1 (1 time)
OHC (1 time)
|
2009 LKB1 and AMP-activated protein kinase control of mTOR signalling and growth.
|
| 11 |
adenosine monophosphate-activated serine/threonine protein kinase
(3 times)
|
Nephrology
(1 time)
|
DN (1 time)
GFR (1 time)
mTOR (1 time)
|
2010 Resveratrol attenuates renal hypertrophy in early-stage diabetes by activating AMPK.
|
| 12 |
AMP-activated PK
(3 times)
|
Pharmacology
(3 times)
|
GLUT4 (1 time)
IRS-1 (1 time)
NTS (1 time)
|
2013 Opposite effects of genistein on the regulation of insulin-mediated glucose homeostasis in adipose tissue.
|
| 13 |
5'AMP-kinase
(2 times)
|
Biochemistry
(1 time)
|
CaMKI (1 time)
CaMKIV (1 time)
CaMKK (1 time)
|
2017 Epigallocatechin-3-gallate (EGCG) activates AMPK through the inhibition of glutamate dehydrogenase in muscle and pancreatic ss-cells: A potential beneficial effect in the pre-diabetic state?
|
| 14 |
AMP-activated kinase protein
(2 times)
|
Complementary Therapies
(1 time)
|
AC (1 time)
ACC (1 time)
DN (1 time)
|
2011 Long-term high-fat diet-induced obesity decreases the cardiac leptin receptor without apparent lipotoxicity.
|
| 15 |
AMP-dependent/activated protein kinase
(2 times)
|
Otolaryngology
(1 time)
|
HFC (1 time)
|
2014 [Metformin inhibits the proliferation of hypopharyngeal carcinoma Fadu cells and enhances the chemotherapeutic sensitivity of cells].
|
| 16 |
AMP-induced protein kinase
(2 times)
|
Drug Therapy
(2 times)
|
---
|
2022 Melatonin ameliorates lung cell inflammation and apoptosis caused by Klebsiella pneumoniae via AMP-activated protein kinase.
|
| 17 |
AMPKalpha
(2 times)
|
Biochemistry
(2 times)
|
AICAR (1 time)
P-AMPKalpha (1 time)
pNPP (1 time)
|
2007 Aging impairs insulin-stimulated glucose uptake in rat skeletal muscle via suppressing AMPKalpha.
|
| 18 |
associated with 5'adenosine monophosphateactivated protein kinase
(2 times)
|
Molecular Biology
(2 times)
|
LC3 (1 time)
mTOR (1 time)
PD (1 time)
|
2017 Overexpression of miR‑185 inhibits autophagy and apoptosis of dopaminergic neurons by regulating the AMPK/mTOR signaling pathway in Parkinson's disease.
|
| 19 |
p-Adenosine 5'-monophosphate-activated protein activated protein kinase
(2 times)
|
Biotechnology
(1 time)
|
DUSP14 (2 times)
ACLT (1 time)
IkappaB (1 time)
|
2019 [Research progress of Adenosine 5'-monophosphate-activated protein kinase in the regulation of glycolipid metabolism].
|
| 20 |
phospho-AMP-activated kinase
(2 times)
|
Cell Biology
(1 time)
|
DSS (1 time)
ELISA (1 time)
hMSCs (1 time)
|
2018 mTOR and ROS regulation by anethole on adipogenic differentiation in human mesenchymal stem cells.
|
| 21 |
5'-AMP-activated protein kinase catalytic subunit
(1 time)
|
Reproductive Medicine
(1 time)
|
CS (1 time)
|
2015 Cigarette smoke exposure triggers the autophagic cascade via activation of the AMPK pathway in mice.
|
| 22 |
activated phosphoAMPactivated protein kinase
(1 time)
|
Molecular Biology
(1 time)
|
ATG (1 time)
mTOR (1 time)
RCC (1 time)
|
2017 Resveratrol-mediated apoptosis in renal cell carcinoma via the p53/AMP‑activated protein kinase/mammalian target of rapamycin autophagy signaling pathway.
|
| 23 |
activates multiple downstream kinases including CaMKI, CaMKIV, 5'AMP-activated protein kinase
(1 time)
|
Biochemistry
(1 time)
|
CaMKKbeta (1 time)
OA (1 time)
PKA (1 time)
|
2020 Phosphorylation and dephosphorylation of Ca2+/calmodulin-dependent protein kinase kinase beta at Thr144 in HeLa cells.
|
| 24 |
Activating Monophosphate-Activated Protein Kinase
(1 time)
|
Medicine
(1 time)
|
LKB1 (1 time)
NF-kappaB (1 time)
NR4A1 (1 time)
|
2020 Interaction of Nuclear Receptor Subfamily 4 Group A Member 1 (Nr4a1) and Liver Linase B1 (LKB1) Mitigates Type 2 Diabetes Mellitus by Activating Monophosphate-Activated Protein Kinase (AMPK)/Sirtuin 1 (SIRT1) Axis and Inhibiting Nuclear Factor-kappa B (NF-kappaB) Activation.
|
| 25 |
activation of hypothalamic monophosphate-dependent kinase
(1 time)
|
Psychiatry
(1 time)
|
ALA (1 time)
|
2013 An open-label pilot trial of alpha-lipoic acid for weight loss in patients with schizophrenia without diabetes.
|
| 26 |
activity by upregulating the intracellular level of 5'AMP-activated kinase
(1 time)
|
Biological Science Disciplines
(1 time)
|
GC-MS (1 time)
RPPA (1 time)
|
2019 Mauritian Endemic Medicinal Plant Extracts Induce G2/M Phase Cell Cycle Arrest and Growth Inhibition of Oesophageal Squamous Cell Carcinoma in Vitro.
|
| 27 |
activity of cAMP-dependent protein kinase
(1 time)
|
Zoology
(1 time)
|
LTs (1 time)
SCP (1 time)
|
2021 Expanded Supercooling Capacity With No Cryoprotectant Accumulation Underlies Cold Tolerance of the European Grapevine Moth.
|
| 28 |
Ad-AMPK-DN
(1 time)
|
Cardiology
(1 time)
|
NO (1 time)
|
2006 Statins activate AMP-activated protein kinase in vitro and in vivo.
|
| 29 |
Additionally, 5'AMPactivated protein kinase
(1 time)
|
Genetics, Medical
(1 time)
|
Bcl (1 time)
BECN1 (1 time)
mTOR (1 time)
|
2018 Autophagy regulates the degeneration of the auditory cortex through the AMPK-mTOR-ULK1 signaling pathway.
|
| 30 |
adenosine monophosphate-activated kinase signaling pathways
(1 time)
|
Diabetes Mellitus
(1 time)
|
DN (1 time)
EMT (1 time)
mTOR (1 time)
|
2017 Research Progress on Mechanism of Podocyte Depletion in Diabetic Nephropathy.
|
| 31 |
adenylate monophosphate mediated-protein kinase
(1 time)
|
Metabolism
(1 time)
|
CAC (1 time)
|
2006 Anaplerotic diet therapy in inherited metabolic disease: therapeutic potential.
|
| 32 |
alpha2-AMP-activated kinase
(1 time)
|
Endocrinology
(1 time)
|
TBC1D4 (1 time)
|
2010 Impaired insulin-induced site-specific phosphorylation of TBC1 domain family, member 4 (TBC1D4) in skeletal muscle of type 2 diabetes patients is restored by endurance exercise-training.
|
| 33 |
alpha2beta2gamma3-AMP-activated protein kinase
(1 time)
|
Endocrinology
(1 time)
|
AS160 (1 time)
|
2006 AS160 phosphorylation is associated with activation of alpha2beta2gamma1- but not alpha2beta2gamma3-AMPK trimeric complex in skeletal muscle during exercise in humans.
|
| 34 |
also demonstrated that 5'AMPactivated protein kinase
(1 time)
|
Molecular Biology
(1 time)
|
EMMPRINs (1 time)
MAPK (1 time)
MMPs (1 time)
|
2018 P2X7 receptor regulates EMMPRIN and MMP‑9 expression through AMPK/MAPK signaling in PMA‑induced macrophages.
|
| 35 |
also significantly increased the expression levels of phosphorylatedAMPactivated protein kinase
(1 time)
|
Molecular Biology
(1 time)
|
IMD (1 time)
MI (1 time)
MMVECs (1 time)
|
2017 Intermedin1‑53 enhances angiogenesis and attenuates adverse remodeling following myocardial infarction by activating AMP‑activated protein kinase.
|
| 36 |
Among these transcripts, serine/threonine-protein kinase
(1 time)
|
Veterinary Medicine
(1 time)
|
HSP70 (1 time)
ND1 (1 time)
qRT-PCR (1 time)
|
2015 Transcriptome profiling of the hypothalamus during prelaying and laying periods in Sichuan white geese (Anser cygnoides).
|
| 37 |
AMP protein activated kinase
(1 time)
|
Biochemistry
(1 time)
|
BDNF (1 time)
CREB (1 time)
FAS (1 time)
|
2017 Effect of brain-derived neurotrophic factor (BDNF) on hepatocyte metabolism.
|
| 38 |
AMP sensor kinase
(1 time)
|
Cell Biology
(1 time)
|
LUAD (1 time)
|
2020 Cytosolic serine hydroxymethyltransferase controls lung adenocarcinoma cells migratory ability by modulating AMP kinase activity.
|
| 39 |
AMP-activated kinase activity
(1 time)
|
Physiology
(1 time)
|
AICAR (1 time)
FA (1 time)
TAG (1 time)
|
2005 AMP kinase activation with AICAR further increases fatty acid oxidation and blunts triacylglycerol hydrolysis in contracting rat soleus muscle.
|
| 40 |
AMP-activated kinase complex
(1 time)
|
Cell Biology
(1 time)
|
CWI (1 time)
|
2017 Cell wall synthesis and central carbohydrate metabolism are interconnected by the SNF1/Mig1 pathway in Kluyveromyces lactis.
|
| 41 |
AMP-activated protein kinase inducing apoptosis
(1 time)
|
Pharmacology
(1 time)
|
---
|
2013 Doxorubicin: an update on anticancer molecular action, toxicity and novel drug delivery systems.
|
| 42 |
AMP-activated protein kinase phosphorylation
(1 time)
|
Cell Biology
(1 time)
|
DSS (1 time)
ESRRA (1 time)
LDA (1 time)
|
2020 ESRRA (estrogen related receptor alpha) is a critical regulator of intestinal homeostasis through activation of autophagic flux via gut microbiota.
|
| 43 |
AMP-activated protein kinase subunit beta-1
(1 time)
|
Food
(1 time)
|
3-MA (1 time)
3DC2ME (1 time)
mTOR (1 time)
|
2020 Unique Triterpenoid of Jujube Root Protects Cisplatin-induced Damage in Kidney Epithelial LLC-PK1 Cells via Autophagy Regulation.
|
| 44 |
AMP-activated protein kinase with energy detection
(1 time)
|
Chemistry
(1 time)
|
TKI (1 time)
|
2019 Phenformin as an Anticancer Agent: Challenges and Prospects.
|
| 45 |
AMP-activated protein kinase/acetyl-CoA carboxylase
(1 time)
|
Endocrinology
(1 time)
|
ACC (1 time)
i.c.v (1 time)
IR (1 time)
|
2008 Intracerebroventricular injection of citrate inhibits hypothalamic AMPK and modulates feeding behavior and peripheral insulin signaling.
|
| 46 |
AMP-dependent kinase serine
(1 time)
|
Chemistry, Pharmaceutical
(1 time)
|
CD36 (1 time)
G6Pase (1 time)
HFD (1 time)
|
2021 High-Efficacy alpha,beta-Dehydromonacolin S Improves Hepatic Steatosis and Suppresses Gluconeogenesis Pathway in High-Fat Diet-Induced Obese Rats.
|
| 47 |
AMP-responsive protein kinase
(1 time)
|
Cell Biology
(1 time)
|
---
|
2008 p53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signaling.
|
| 48 |
AMP-ribose activating kinase
(1 time)
|
Biology
(1 time)
|
JNK (1 time)
TXM (1 time)
ZDF (1 time)
|
2014 Thioredoxin-mimetic peptide CB3 lowers MAPKinase activity in the Zucker rat brain.
|
| 49 |
AMP-sensitive protein kinase
(1 time)
|
Complementary Therapies
(1 time)
|
AS-IV (1 time)
mTOR (1 time)
TUNEL (1 time)
|
2022 Astragaloside IV pre-treatment attenuates PM2.5-induced lung injury in rats: Impact on autophagy, apoptosis and inflammation.
|
| 50 |
AMPK-ASKO mice
(1 time)
|
Cell Biology
(1 time)
|
FA (1 time)
HSL (1 time)
TAG (1 time)
|
2016 AMPK Phosphorylates Desnutrin/ATGL and Hormone-Sensitive Lipase To Regulate Lipolysis and Fatty Acid Oxidation within Adipose Tissue.
|
| 51 |
AMPK-deficient HSCs
(1 time)
|
Science
(1 time)
|
HSC (1 time)
|
2010 Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells.
|
| 52 |
AMPKalpha, beta, and gamma
(1 time)
|
Biochemistry
(1 time)
|
---
|
2021 Cloning and characterization of AMP-activated protein kinase genes in Daphnia pulex: Modulation of AMPK gene expression in response to polystyrene nanoparticles.
|
| 53 |
another CaMKK2 target, 5'AMP-dependent protein kinase
(1 time)
|
Cells
(1 time)
|
CaM (1 time)
EGF (1 time)
PFKP (1 time)
|
2022 Calcium/calmodulin-dependent protein kinase kinase 2 mediates pleiotropic effects of epidermal growth factor in cancer cells.
|
| 54 |
associated with 5'AMP-dependent protein kinase
(1 time)
|
Neurology
(1 time)
|
GIRKs (1 time)
|
2007 Phospho-dependent functional modulation of GABA(B) receptors by the metabolic sensor AMP-dependent protein kinase.
|
| 55 |
auditory system protection by activating adenylate activated kinase
(1 time)
|
Synapses
(1 time)
|
ABR (1 time)
NE (1 time)
SC (1 time)
|
2022 Killer or helper? The mechanism underlying the role of adenylate activated kinase in sound conditioning.
|
| 56 |
autophagy and 5'AMPactivated protein kinase
(1 time)
|
Molecular Biology
(1 time)
|
circSAMD4A (1 time)
miR (1 time)
PD (1 time)
|
2021 circSAMD4A participates in the apoptosis and autophagy of dopaminergic neurons via the miR‑29c‑3p‑mediated AMPK/mTOR pathway in Parkinson's disease.
|
| 57 |
investigatedAMP-activated protein kinase
(1 time)
|
Medicine
(1 time)
|
ALS (1 time)
PP2A (1 time)
SOD1 (1 time)
|
2014 Mutant TDP-43 deregulates AMPK activation by PP2A in ALS models.
|
| 58 |
metformin, an adenosine monophosphate-activated kinase
(1 time)
|
Clinical Medicine
(1 time)
|
OPTN (1 time)
|
2022 Metformin promotes histone deacetylation of optineurin and suppresses tumour growth through autophagy inhibition in ocular melanoma.
|
| 59 |
miR-34a/SIRT1:AMP-activated protein kinase
(1 time)
|
Genetics, Medical
(1 time)
|
Mfn2 (1 time)
miRs (1 time)
NAFLD (1 time)
|
2019 Skeletal muscle miR-34a/SIRT1:AMPK axis is activated in experimental and human non-alcoholic steatohepatitis.
|
| 60 |
mitogen-activated protein kinase
(1 time)
|
|
DEGs (1 time)
GO (1 time)
PCK2 (1 time)
|
2021 Identification of Differentially Expressed Genes and Lipid Metabolism Signaling Pathways between Muscle and Fat Tissues in Broiler Chickens.
|
| 61 |
p-AMPK meaning that the adenosine-activated protein kinase
(1 time)
|
Environmental Health
(1 time)
|
mTOR (1 time)
|
2019 Mesoporous silica induces hippocampal neurons cell autophagy through AMPK/mTOR/P70S6K signaling pathway.
|
| 62 |
phosphorylated-adenosine monophosphate kinase
(1 time)
|
Biochemistry
(1 time)
|
BTHS (1 time)
TAG (1 time)
|
2017 Glucose Uptake and Triacylglycerol Synthesis Are Increased in Barth Syndrome Lymphoblasts.
|
| 63 |
potent-AMP-kinase
(1 time)
|
Biochemistry
(1 time)
|
LD (1 time)
|
2008 Preparative enantiomeric separation of potent AMP-activated protein kinase activator by HPLC on amylose-based chiral stationary phase. Determination of enantiomeric purity and assignment of absolute configuration.
|
A Search Service for Abbreviation / Long Form