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Abbreviation: BPDE
Appearance Frequency: 545 time(s)
Long forms: 47

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Long Form No. Long Form Research Area Co-occurring Abbreviation PubMed/MEDLINE Info. (Year, Title)
benzo(a)pyrene diol epoxide
(258 times)
Neoplasms
(85 times)
NER (20 times)
PAH (15 times)
OR (12 times)
1982 Effects of benzo[a]pyrene diol epoxide adducts on DNA synthesis in mammalian cells.
benzo(a)pyrene-7,8-diol-9,10-epoxide
(126 times)
Neoplasms
(30 times)
BaP (20 times)
BP (12 times)
PAHs (11 times)
1980 Genetic factors in Escherichia coli that affect cell killing and mutagenesis induced by benzo(a)pyrene-7,8-dihydrodiol 9,10-oxide.
B(a)P-7,8-dihydrodiol-9,10-epoxide
(35 times)
Toxicology
(14 times)
BaP (13 times)
BP (5 times)
PAH (5 times)
1989 Transport of DNA-adducting metabolites in mouse serum following benzo[a]pyrene administration.
beta,8 alpha-dihydroxy-9 alpha,10 alpha-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene
(31 times)
Neoplasms
(10 times)
PAH (5 times)
1-NOP (4 times)
ACIS (3 times)
1983 Carcinogenic activity of benzo[a]pyrene and some of its synthetic derivatives by direct injection into the mouse fetus.
B(a)P diol epoxide
(22 times)
Toxicology
(6 times)
BaP (11 times)
BP (5 times)
PAH (2 times)
1985 Benzo(a)pyrene diolepoxide-DNA adducts detected by synchronous fluorescence spectrophotometry.
benzo(a)pyrene, to trans-7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene
(15 times)
Biochemistry
(4 times)
me (2 times)
NER (2 times)
PAH (2 times)
1982 Mechanism for the loss of preferential benzo [a] pyrene binding to the linker DNA of chromatin.
benzo(a)pyrene dihydrodiol epoxide
(10 times)
Cell Biology
(3 times)
5AzC (1 time)
DSBs (1 time)
IR (1 time)
1988 Anti-tumor surveillance of non-contact-inhibited transformed cell lines.
beta-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene
(3 times)
Biochemistry
(1 time)
BP (1 time)
CDNB (1 time)
EA (1 time)
1979 Benzo(a)pyrene-7,8-dihydrodiol 9,10-oxide adenosine and deoxyadenosine adducts: structure and stereochemistry.
alpha-epoxy-7,8,9,10-tetrahydro-BP
(2 times)
Toxicology
(1 time)
BP (2 times)
2-AAF (1 time)
BPD (1 time)
1988 Benzo[a]pyrene metabolism and induction of enzyme-altered foci in regenerating rat liver.
10  anti-BP diol epoxide
(2 times)
Toxicology
(1 time)
BP (1 time)
HPV (1 time)
HRP (1 time)
1996 Expanded analysis of benzo[a]pyrene-DNA adducts formed in vitro and in mouse skin: their significance in tumor initiation.
11  B(a)P metabolite 7r, 8t-dihydroxy-9t,10t-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene
(2 times)
Neoplasms
(2 times)
TCDD (2 times)
AhR (1 time)
ER (1 time)
1999 Inhibition of BRCA-1 expression by benzo[a]pyrene and its diol epoxide.
12  BaP trans-7,8-diol-anti-9,10-epoxide
(2 times)
Food Analysis
(1 time)
BaP (2 times)
BaP t-7,8-diol (1 time)
PAH (1 time)
2013 UVA photoirradiation of benzo[a]pyrene metabolites: induction of cytotoxicity, reactive oxygen species, and lipid peroxidation.
13  benzo(a)pyrene-7,8-9,10-diol epoxide
(2 times)
Neoplasms
(1 time)
AC (1 time)
AGVA (1 time)
ANOVA (1 time)
2008 Single Nucleotide Polymorphisms in Selected Apoptotic Genes and BPDE-Induced Apoptotic Capacity in Apparently Normal Primary Lymphocytes: A Genotype-Phenotype Correlation Analysis.
14  beta-dihydroxy-9 beta,10 beta-epoxy-7,8,9,10 tetrahydrobenzo(a)pyrene
(2 times)
Science
(1 time)
BP (1 time)
1980 The binding of benzo(a)pyrene to DNA components of differing sequence complexity.
15  10-tetrahydro-BP
(1 time)
Toxicology
(1 time)
BA (1 time)
BADE (1 time)
BP (1 time)
1996 Influence of Na+ on DNA reactions with aromatic epoxides and diol epoxides: evidence that DNA catalyzes the formation of benzo[a]pyrene and benz[a]anthracene adducts at intercalation sites.
16  7,8,9,10-tetrahydro-benzo(a)pyrenes
(1 time)
Neoplasms
(1 time)
BP (1 time)
1987 Sulfite-dependent mutagenicity of benzo[a]pyrene derivatives.
17  7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydro-B(a)P
(1 time)
Pharmacology
(1 time)
--- 1992 Generation of 7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene by murine splenic macrophages.
18  alpha-benzo(a)pyrene epoxide
(1 time)
Neoplasms
(1 time)
BP (1 time)
1985 Detection of benzo(a)pyrene:DNA adducts in human white blood cells.
19  B(a)P metabolises to diol epoxide
(1 time)
Biomedical Engineering
(1 time)
BPDE-dG (1 time)
HRMS (1 time)
PAH (1 time)
2020 DNA as an in vitro trapping agent for detection of bulky genotoxic metabolites.
20  B(a)P-diol to the carcinogen (+)-benzo(a)pyrene-7,8-dihydroxy-9,10-epoxide
(1 time)
Neoplasms
(1 time)
HMEC (1 time)
1991 Metabolism of benzo[a]pyrene and benzo[a]pyrene-7,8-dihydrodiol in human mammary epithelial cells: feedback inhibition by 7-hydroxybenzo[a]pyrene.
21  BaP diol epoxide deoxyguanosine
(1 time)
Pharmacology
(1 time)
BaP (1 time)
1989 Effects of adsorption of benzo[a]pyrene onto carbon black particles on levels of DNA adducts in lungs of rats exposed by inhalation.
22  BaP diol-epoxidation
(1 time)
Medicine
(1 time)
BaP (1 time)
ROS (1 time)
VE (1 time)
2014 Curcumin and vitamin E protect against adverse effects of benzo[a]pyrene in lung epithelial cells.
23  BaP, its diol epoxide metabolite
(1 time)
Biochemistry
(1 time)
BaP (1 time)
Type II (1 time)
2008 Genotoxicity of combined exposure to polycyclic aromatic hydrocarbons and UVA--a mechanistic study.
24  BaP-7,8-9,10-diol epoxide
(1 time)
Pharmacology
(1 time)
ANF (1 time)
BaP (1 time)
PAHs (1 time)
1998 Apoptosis in Daudi human B cells in response to benzo[a]pyrene and benzo[a]pyrene-7,8-dihydrodiol.
25  bay region PAH derivative, trans-7,8-dihydroxy-anti-9,10-epoxy-7,8,9, 10-tetrahydroxybenzo(a)pyrene
(1 time)
Neoplasms
(1 time)
CHO (1 time)
dA (1 time)
DHFR (1 time)
1995 Mutagenic specificity of syn-benzo[g]chrysene 11,12-dihydrodiol 13,14-epoxide in the dihydrofolate reductase gene of Chinese hamster ovary cells.
26  bay-region diol epoxide of BP
(1 time)
Toxicology
(1 time)
BP (1 time)
BP-6-C8Gua (1 time)
BP-6-N7Gua (1 time)
1992 Identification and quantitation of benzo[a]pyrene-DNA adducts formed by rat liver microsomes in vitro.
27  Bayesian phase difference estimation
(1 time)
Biophysics
(1 time)
BPE (1 time)
full-CI (1 time)
IQPE (1 time)
2021 Bayesian phase difference estimation: a general quantum algorithm for the direct calculation of energy gaps.
28  been ascribed in part to the formation of anti-trans-7,8-dihydroxy-7,8-dihydroB(a)P-9,10-epoxide
(1 time)
Biochemistry
(1 time)
BPQ (1 time)
2010 Lack of contribution of covalent benzo[a]pyrene-7,8-quinone-DNA adducts in benzo[a]pyrene-induced mouse lung tumorigenesis.
29  been shown to block the ability of the carcinogen 7-r,8-t-dihydroxy-9-t,10-t-oxy-7,8,9,10-tetrahydrobenzo(a)pyrene
(1 time)
Toxicology
(1 time)
--- 1993 Reaction of nontoxic, potentially chemopreventive purinethiols with a direct-acting, electrophilic carcinogen, benzo[a]pyrene-7,8-diol 9,10-epoxide.
30  benzo(a)pyrene epoxide(trans)
(1 time)
Cell Biology
(1 time)
--- 1988 Cytoplasmic suppression of tumor progression in reconstituted cells.
31  benzo(a)pyrene that yields the highly mutagenic (+)-anti-7,8-diol-9,10 epoxide
(1 time)
Neoplasms
(1 time)
CI (1 time)
mEH (1 time)
OR (1 time)
2001 Lung cancer susceptibility in relation to combined polymorphisms of microsomal epoxide hydrolase and glutathione S-transferase P1.
32  benzo(a)pyrene-7,8,9,10-tetrahydro-7,8-dihydrodiol-9,10-epoxide
(1 time)
Chemistry Techniques, Analytical
(1 time)
CZE (1 time)
ds (1 time)
MS (1 time)
2007 Application of pressure assisted electrokinetic injection technique in the measurements of DNA oligonucleotides and their adducts using capillary electrophoresis-mass spectrometry.
33  beta,8 alpha-dihydroxy-9 alpha, 10 alpha-epoxybenzo(a)pyrene
(1 time)
Biochemistry
(1 time)
--- 1985 Enhancement of stability of 7 beta,8 alpha-dihyroxy-9 alpha epoxybenzo(a)pyrene by complex formation with serum albumin.
34  between 7r, 8t-dihydroxy-9t,10t-epoxy-7,8,9,10-tetrahydrobenzo(alpha) pyrene
(1 time)
Toxicology
(1 time)
--- 1998 Role of hydrophobic effects in the reaction of a polynuclear aromatic diol epoxide with oligodeoxynucleotides in aqueous solutions.
35  between deoxyguanosine and (+)-anti-BP diol epoxide
(1 time)
Neoplasms
(1 time)
BP (1 time)
1987 Covalent binding of benzo[a]pyrene to macromolecules in lung and liver of rats following intratracheal instillation.
36  between its diol epoxide metabolite, (+)-anti-7r,8t-dihydroxy-c9,10-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene
(1 time)
Biochemistry
(1 time)
LM-PCR (1 time)
2002 Formation of benzo[a]pyrene diol epoxide-DNA adducts at specific guanines within K-ras and p53 gene sequences: stable isotope-labeling mass spectrometry approach.
37  binding of fluorescent (+)-anti-BP-7,8-diol-9,10-epoxide
(1 time)
Pathology
(1 time)
--- 1984 Fluorescence measurements of DNA-bound metabolites of benzo(a)pyrene derivatives with different carcinogenic effects.
38  binding of the carcinogen, 7r,8t-dihydroxy-9t,10t-oxy-7,8,9,10-tetrahydrobenzo(a)pyrene
(1 time)
Neoplasms
(1 time)
--- 1995 Binding of the transcription factor, Sp1, to non-target sites in DNA modified by benzo[a]pyrene diol epoxide.
39  biphenylene diacid
(1 time)
Polymers
(1 time)
Calc'd Mw (1 time)
PEPE (1 time)
Tg (1 time)
2022 Improved Melt Processabilities of Thermosetting Polyimide Matrix Resins for High Temperature Carbon Fiber Composite Applications.
40  bovine serum albumin complex of DNA modified with (+/-)trans-7,8-dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo(a)pyre ne
(1 time)
Neoplasms
(1 time)
ELISA (1 time)
roGuo-8-AF (1 time)
1988 Binding efficiency of antibodies to DNA modified with aromatic amines and polycyclic aromatic hydrocarbons: implications for quantification of carcinogen-DNA adducts in vivo.
41  BP derivatives, among which the ultimate carcinogen (+)-anti-BP-7,8-diol-9,10-epoxide
(1 time)
Toxicology
(1 time)
BP (1 time)
PAH (1 time)
2012 Metabolically competent human skin models: activation and genotoxicity of benzo[a]pyrene.
42  BP tetrols derived from syn- and anti-7,8-dihydroxy-9,10-oxy-7,8,9,10-tetrahydroxybenzo(a)pyrene
(1 time)
Biochemistry
(1 time)
BP (1 time)
PAH (1 time)
1988 Stereoselective aspects of the metabolic activation of benzo[a]pyrene by human skin in vitro.
43  BP-DNA adducts: An HPLC/fluorimetry assay suitable for measuring (+)-anti-BP-diol-epoxide
(1 time)
Genetics
(1 time)
3-alkAde (1 time)
BP (1 time)
WBC (1 time)
1996 DNA adducts in human carcinogenesis: etiological relevance and structure-activity relationship.
44  BP-metabolite, that is, (+)-anti-BP-7,8-diol-9,10-epoxide
(1 time)
Cell Biology
(1 time)
AhR (1 time)
BP (1 time)
2012 Activation of the aryl hydrocarbon receptor sensitises human keratinocytes for CD95L- and TRAIL-induced apoptosis.
45  bromo diphenyl ether
(1 time)
Biology
(1 time)
AChE (1 time)
BPA (1 time)
DPA (1 time)
2008 Multixenobiotic resistance, acetyl-choline esterase activity and total oxyradical scavenging capacity of the Arctic spider crab, Hyasaraneus, following exposure to bisphenol A, tetra bromo diphenyl ether and diallyl phthalate.
46  trans-7,8-dihydrobenzo(alpha)pyrene-7,8-diol-9,10-epoxide
(1 time)
Biochemistry
(1 time)
--- 1983 The binding of a carcinogen to the nucleosomal and non-nucleosomal regions of the simian virus 40 chromosome in vivo.
47  trans-7,8-diol-anti-9,10-epoxy-benzo(a)pyrene
(1 time)
Neoplasms
(1 time)
--- 1989 Identification of conformationally different binding sites in benzo[a]pyrene diol epoxide--DNA adducts by low-temperature fluorescence spectroscopy.