| 1 |
CXC chemokine receptor 4
(1266 times)
|
Neoplasms
(207 times)
|
SDF-1 (174 times)
SDF-1alpha (79 times)
CXCL12 (69 times)
|
1996 The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry.
|
| 2 |
CXC receptor 4
(64 times)
|
Neoplasms
(13 times)
|
SDF-1 (15 times)
CXCL12 (7 times)
AML (3 times)
|
2002 Stromal cell-derived factor 1 (CXCL12) induces monocyte migration into human synovium transplanted onto SCID Mice.
|
| 3 |
C-X-C motif receptor 4
(39 times)
|
Neurology
(8 times)
|
CXCL12 (12 times)
SDF-1 (5 times)
SDF1 (3 times)
|
2005 G-CSF potently inhibits osteoblast activity and CXCL12 mRNA expression in the bone marrow.
|
| 4 |
C-X-C receptor type 4
(9 times)
|
Histocytochemistry
(2 times)
|
SDF-1alpha (5 times)
HCC (3 times)
GSCs (2 times)
|
2013 Differential effects of sorafenib on liver versus tumor fibrosis mediated by stromal-derived factor 1 alpha/C-X-C receptor type 4 axis and myeloid differentiation antigen-positive myeloid cell infiltration in mice.
|
| 5 |
cysteine-X-cysteine chemokine receptor 4
(4 times)
|
Cell Transformation, Neoplastic
(1 time)
|
AIS (1 time)
APP (1 time)
HPV (1 time)
|
2018 Adaptive Immunodeficiency in WHIM Syndrome.
|
| 6 |
CXCR4WT
(3 times)
|
Molecular Biology
(1 time)
|
CTD (1 time)
EMT (1 time)
ERK (1 time)
|
2000 beta-arrestin differentially regulates the chemokine receptor CXCR4-mediated signaling and receptor internalization, and this implicates multiple interaction sites between beta-arrestin and CXCR4.
|
| 7 |
cell surface expression of chemokine receptor 4
(2 times)
|
Natural Science Disciplines
(1 time)
|
EPCs (1 time)
T1D (1 time)
|
2021 Type 1 diabetes patients increase CXCR4+ and CXCR7+ haematopoietic and endothelial progenitor cells with exercise, but the response is attenuated.
|
| 8 |
chemokine (CXC motif) receptor4
(2 times)
|
Molecular Biology
(2 times)
|
bFGF (1 time)
CCK (1 time)
CNV (1 time)
|
2016 CXCL12/CXCR4 axis regulates neovascularization and lymphangiogenesis in sutured corneas in mice.
|
| 9 |
CXC-type receptor 4
(2 times)
|
Science
(1 time)
|
ABMT (1 time)
GPCR (1 time)
GPCRs (1 time)
|
2010 Discovery of a CXCR4 agonist pepducin that mobilizes bone marrow hematopoietic cells.
|
| 10 |
CXCL12 and its receptor chemokine receptor 4
(2 times)
|
Neoplasms
(1 time)
|
OC (1 time)
|
2012 A review on CXCR4/CXCL12 axis in oncology: no place to hide.
|
| 11 |
CXCR4 siRNA
(2 times)
|
Medicine
(1 time)
|
alpha-SMA (1 time)
AP-1 (1 time)
CTGF (1 time)
|
2014 CXCL12 induces connective tissue growth factor expression in human lung fibroblasts through the Rac1/ERK, JNK, and AP-1 pathways.
|
| 12 |
CXCR4-B16
(2 times)
|
Neoplasms
(2 times)
|
CCR (1 time)
CXCR (1 time)
LSEC (1 time)
|
2002 Expression of CXC chemokine receptor-4 enhances the pulmonary metastatic potential of murine B16 melanoma cells.
|
| 13 |
CXCR4-DeltaCTD
(2 times)
|
Neoplasms
(1 time)
|
CTD (1 time)
EMT (1 time)
ERK (1 time)
|
2006 Deletion of the COOH-terminal domain of CXC chemokine receptor 4 leads to the down-regulation of cell-to-cell contact, enhanced motility and proliferation in breast carcinoma cells.
|
| 14 |
CXCR4-MSCs
(2 times)
|
Biophysics
(1 time)
|
MSCs (2 times)
BM (1 time)
HSCs (1 time)
|
2008 Targeted migration of mesenchymal stem cells modified with CXCR4 gene to infarcted myocardium improves cardiac performance.
|
| 15 |
cysteine-X-cysteine receptor 4
(2 times)
|
Gastroenterology
(1 time)
|
CCR5 (1 time)
GFP (1 time)
HCV (1 time)
|
2010 Human immunodeficiency virus (HIV)-1 infects human hepatic stellate cells and promotes collagen I and monocyte chemoattractant protein-1 expression: implications for the pathogenesis of HIV/hepatitis C virus-induced liver fibrosis.
|
| 16 |
C-X-C chemokine GPCR type 4
(1 time)
|
Biotechnology
(1 time)
|
GPCRs (1 time)
|
2016 Chaperonin-enhanced Escherichia coli cell-free expression of functional CXCR4.
|
| 17 |
C-X-C chemokine ligand 12 receptor 4
(1 time)
|
Cell Biology
(1 time)
|
ACR (1 time)
COX-2 (1 time)
iNOS (1 time)
|
2018 Troxerutin Protects Kidney Tissue against BDE-47-Induced Inflammatory Damage through CXCR4-TXNIP/NLRP3 Signaling.
|
| 18 |
C-X-C chemokine motif receptor 4
(1 time)
|
Molecular Biology
(1 time)
|
ACKR3 (1 time)
CXCL12 (1 time)
|
2022 Effects of Small Molecule Ligands on ACKR3 Receptors.
|
| 19 |
C-X-C motif chemokine ligand receptor-4
(1 time)
|
Vascular Diseases
(1 time)
|
SDF (1 time)
VEGF (1 time)
|
2020 Loss of Down Syndrome Critical Region-1 Mediated-Hypercholesterolemia Accelerates Corneal Opacity Via Pathological Neovessel Formation.
|
| 20 |
cell-surface CXC chemokine receptor-4
(1 time)
|
General Surgery
(1 time)
|
IVC (1 time)
WT (1 time)
|
2012 Vein graft neointimal hyperplasia is exacerbated by CXCR4 signaling in vein graft-extrinsic cells.
|
| 21 |
cells demonstrated an increased expression of CD184
(1 time)
|
Stem Cells
(1 time)
|
BMSCs (1 time)
SP (1 time)
|
2010 Bone marrow stromal cells from myeloma patients support the growth of myeloma stem cells.
|
| 22 |
cells overexpress chemokine receptor type 4
(1 time)
|
Cell Biology
(1 time)
|
ECM (1 time)
MMPs (1 time)
MT2-MMP (1 time)
|
2020 Arg kinase mediates CXCL12/CXCR4-induced invadopodia formation and invasion of glioma cells.
|
| 23 |
cells with membranous overexpression of the chemokine receptor 4
(1 time)
|
Natural Science Disciplines
(1 time)
|
Ad (1 time)
CD (1 time)
|
2017 Obtaining control of cell surface functionalizations via Pre-targeting and Supramolecular host guest interactions.
|
| 24 |
chemokine CXC receptor4
(1 time)
|
Genetics, Medical
(1 time)
|
Cdc42 (1 time)
CRC (1 time)
CXCL12 (1 time)
|
2021 MTSS1 inhibits colorectal cancer metastasis by regulating the CXCR4/CXCL12 signaling axis.
|
| 25 |
chemotaxis cytokines receptor 4
(1 time)
|
Complementary Therapies
(1 time)
|
CCK-8 (1 time)
EMT (1 time)
MMP-2 (1 time)
|
2014 Fibroblasts weaken the anti-tumor effect of gefitinib on co-cultured non-small cell lung cancer cells.
|
| 26 |
clinical relevance of expression of chemokine receptor 4
(1 time)
|
Pathology
(1 time)
|
CIs (1 time)
CRC (1 time)
HRs (1 time)
|
2014 The association of CXCR4 expression with prognosis and clinicopathological indicators in colorectal carcinoma patients: a meta-analysis.
|
| 27 |
comprise largely of astrocytic progenitors expressing chemokine receptor 4
(1 time)
|
Neoplasms
(1 time)
|
NSCs (1 time)
|
2004 Glioma tropic neural stem cells consist of astrocytic precursors and their migratory capacity is mediated by CXCR4.
|
| 28 |
confirmed overexpression of the chemokine receptor 4
(1 time)
|
Nuclear Medicine
(1 time)
|
ACC (1 time)
|
2016 Investigating the Chemokine Receptor 4 as Potential Theranostic Target in Adrenocortical Cancer Patients.
|
| 29 |
Contrary to our expectations, CD184
(1 time)
|
Hematology
(1 time)
|
PBSCs (1 time)
|
2013 CD31 expression on peripheral blood stem cells predicts both early neutrophil and platelet engraftments.
|
| 30 |
Cxc Chemokin Receptor 4
(1 time)
|
Biochemistry
(1 time)
|
mNSS (1 time)
NSPCs (1 time)
SD (1 time)
|
2015 Effect of integrin combined laminin on peripheral blood vessel of cerebral infarction and endogenous nerve regeneration.
|
| 31 |
CXC chemokine-binding receptor 4
(1 time)
|
Vascular Diseases
(1 time)
|
CCR3 (1 time)
|
2008 CCR3- and CXCR4-mediated interactions regulate migration of CD34+ human bone marrow progenitors to ischemic myocardium and subsequent tissue repair.
|
| 32 |
CXC chemotaxis factor receptor 4
(1 time)
|
Complementary Therapies
(1 time)
|
BMMNC (1 time)
HS (1 time)
LT (1 time)
|
2003 [Effect of ligustrazine on bone marrow hematopoiesis in mice after bone marrow transplantation].
|
| 33 |
CXC subfamily receptor 4
(1 time)
|
Dentistry
(1 time)
|
ALP (1 time)
BMSC (1 time)
MMP (1 time)
|
2018 [(*)AG490 could suppress bone marrow mesenchymal stem cells migration, mineralization and bone defect healing via inhibiting Jak2-STAT3 pathway].
|
| 34 |
CXCL11, CXC receptor 4
(1 time)
|
Clinical Laboratory Techniques
(1 time)
|
CXC (1 time)
FOXP3 (1 time)
HCC (1 time)
|
2019 Forkhead box P3 gene silencing inhibits the expression of chemokines and chemokine receptors associated with cell growth, migration, and apoptosis in hepatocellular carcinoma cells.
|
| 35 |
CXCR4-ED
(1 time)
|
Chemistry
(1 time)
|
ECL1 and 2 (1 time)
HIV-1 (1 time)
NT (1 time)
|
2013 Anti-HIV-1 peptide derivatives based on the HIV-1 Co-receptor CXCR4.
|
| 36 |
CXCR4-tropic
(1 time)
|
Chemistry
(1 time)
|
CCR5 (1 time)
|
2005 CCR5 antagonists: host-targeted antivirals for the treatment of HIV infection.
|
| 37 |
CXCR4Mut
(1 time)
|
Hematology
(1 time)
|
WM (1 time)
|
2021 Phase 1 study of ibrutinib and the CXCR4 antagonist ulocuplumab in CXCR4-mutated Waldenstrom macroglobulinemia.
|
| 38 |
CXCR4null
(1 time)
|
Science
(1 time)
|
---
|
2001 Mechanism of human stem cell migration and repopulation of NOD/SCID and B2mnull NOD/SCID mice. The role of SDF-1/CXCR4 interactions.
|
| 39 |
CXCR4R334X
(1 time)
|
Immune System Diseases
(1 time)
|
BM (1 time)
GOF (1 time)
NK (1 time)
|
2019 Enhanced Bone Marrow Homing of Natural Killer Cells Following mRNA Transfection With Gain-of-Function Variant CXCR4R334X.
|
| 40 |
cysteine-X-cysteine receptor 4, octamer-4
(1 time)
|
Gastroenterology
(1 time)
|
CD44 (1 time)
HCC (1 time)
|
2011 Matrix stiffness modulates proliferation, chemotherapeutic response, and dormancy in hepatocellular carcinoma cells.
|
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