| 1 |
epithelial sodium channel
(2197 times)
|
Physiology
(658 times)
|
CFTR (158 times)
CF (126 times)
NCC (82 times)
|
1994 Membrane topology of the amiloride-sensitive epithelial sodium channel.
|
| 2 |
expression and activity of the epithelial sodium channel
(9 times)
|
Nephrology
(3 times)
|
AT1R (1 time)
BPD (1 time)
CFTR (1 time)
|
1998 Salt and water transport across the alveolar epithelium in the developing lung: correlations between function and recent molecular biology advances (Review).
|
| 3 |
epithelial amiloride-sensitive sodium channel
(8 times)
|
Molecular Biology
(3 times)
|
AGT (1 time)
alphaENaC (1 time)
AMPK (1 time)
|
1996 Cell surface expression of the epithelial Na channel and a mutant causing Liddle syndrome: a quantitative approach.
|
| 4 |
enhanced epithelial sodium channel
(5 times)
|
Endocrinology
(2 times)
|
ACTH (1 time)
ADH (1 time)
ALI/ARDS (1 time)
|
2010 Hyperaldosteronism in Klotho-deficient mice.
|
| 5 |
epithelial sodium channel activity
(5 times)
|
Physiology
(1 time)
|
AM (1 time)
ARDS (1 time)
ATP (1 time)
|
1999 Mutational analysis of cysteine-rich domains of the epithelium sodium channel (ENaC). Identification of cysteines essential for channel expression at the cell surface.
|
| 6 |
epithelial Na(+)-selective channel
(2 times)
|
Physiology
(1 time)
|
CCD (1 time)
CF (1 time)
DCT (1 time)
|
1996 Cell-specific expression of amiloride-sensitive, Na(+)-conducting ion channels in the kidney.
|
| 7 |
excessive Na(+) absorption through the epithelial sodium channel
(2 times)
|
Biochemistry
(2 times)
|
CF (2 times)
ASL (1 time)
CFTR (1 time)
|
2006 Airway surface liquid volume regulates ENaC by altering the serine protease-protease inhibitor balance: a mechanism for sodium hyperabsorption in cystic fibrosis.
|
| 8 |
expression of Na-K ATPase and epithelial sodium channel
(2 times)
|
Medicine
(1 time)
|
ALI (1 time)
AQP1 (1 time)
BAL (1 time)
|
2007 [Effect of aldosterone on aquaporin and ionophorous protein expressions in guinea pig cochlea].
|
| 9 |
extrarenal epithelial sodium channel
(2 times)
|
Physiology
(1 time)
|
ECs (1 time)
EnNaC (1 time)
PROBE (1 time)
|
2011 Body fluid expansion in acromegaly is related to enhanced epithelial sodium channel (ENaC) activity.
|
| 10 |
alpha,beta,gamma-epithelial sodium channels
(1 time)
|
Biochemistry
(1 time)
|
CAP3 (1 time)
MAPs (1 time)
|
2012 Energetic and structural basis for activation of the epithelial sodium channel by matriptase.
|
| 11 |
alphabetagamma-epithelial Na+ channel
(1 time)
|
Pulmonary Medicine
(1 time)
|
---
|
2004 cAMP-stimulated Na+ transport in H441 distal lung epithelial cells: role of PKA, phosphatidylinositol 3-kinase, and sgk1.
|
| 12 |
ear function and that epithelial sodium channels
(1 time)
|
Genetic Phenomena
(1 time)
|
AF-SSNHL (1 time)
HF-SSNHL (1 time)
LF-SSNHL (1 time)
|
2022 Association of alphaENaC p. Ala663Thr Gene Polymorphism With Sudden Sensorineural Hearing Loss.
|
| 13 |
early aldosterone action on epithelial sodium channel
(1 time)
|
Molecular Biology
(1 time)
|
PI3Ks (1 time)
|
2014 Phosphoinositide 3-kinase pathway mediates early aldosterone action on morphology and epithelial sodium channel in mammalian renal epithelia.
|
| 14 |
EET-A inhibits epithelial sodium channel
(1 time)
|
Medicine
(1 time)
|
EET-A (2 times)
Ang II (1 time)
EETs (1 time)
|
2014 Epoxyeicosatrienoic acid analogue lowers blood pressure through vasodilation and sodium channel inhibition.
|
| 15 |
effect on Na(+) channel
(1 time)
|
Physiology
(1 time)
|
---
|
2002 Segmental variability of ENaC subunit expression in rat colon during dietary sodium depletion.
|
| 16 |
effects against epithelial sodium channels
(1 time)
|
Chemistry
(1 time)
|
HMA (1 time)
uPA (1 time)
|
2018 6-Substituted Hexamethylene Amiloride (HMA) Derivatives as Potent and Selective Inhibitors of the Human Urokinase Plasminogen Activator for Use in Cancer.
|
| 17 |
electrogenic Na+ transport by the epithelial sodium channel
(1 time)
|
Biomedical Research
(1 time)
|
---
|
2019 Potassium acts through mTOR to regulate its own secretion.
|
| 18 |
electrogenic, amiloride-sensitive, epithelial sodium channel
(1 time)
|
Nephrology
(1 time)
|
---
|
2010 Vasopressin-dependent coupling between sodium transport and water flow in a mouse cortical collecting duct cell line.
|
| 19 |
Electroporation-mediated gene delivery of epithelial sodium channel
(1 time)
|
Cardiology
(1 time)
|
ARDS (1 time)
|
2014 Electroporation-mediated gene delivery of Na+,K+ -ATPase, and ENaC subunits to the lung attenuates acute respiratory distress syndrome in a two-hit porcine model.
|
| 20 |
elegans and subunits of the mammalian epithelial sodium channel
(1 time)
|
Physiology
(1 time)
|
ASICs (1 time)
DEG (1 time)
|
2022 The diverse functions of the DEG/ENaC family: linking genetic and physiological insights.
|
| 21 |
ENaC/degenerin family of ion channels include the epithelial sodium channel
(1 time)
|
Physiology
(1 time)
|
ASICs (2 times)
|
2002 An external site controls closing of the epithelial Na+ channel ENaC.
|
| 22 |
ENaC/degenerin ion channel superfamily includes the amiloride-sensitive epithelial sodium channel
(1 time)
|
Biomedical Research
(1 time)
|
ASIC (1 time)
|
2016 Potential Roles of Amiloride-Sensitive Sodium Channels in Cancer Development.
|
| 23 |
encode alpha, beta or gamma subunit of epithelial sodium channels
(1 time)
|
Biochemistry
(1 time)
|
PHA (1 time)
PRA (1 time)
|
2008 Renin-aldosterone response, urinary Na/K ratio and growth in pseudohypoaldosteronism patients with mutations in epithelial sodium channel (ENaC) subunit genes.
|
| 24 |
encoding for a Na+ channel protein
(1 time)
|
Nephrology
(1 time)
|
---
|
2011 Proteomics and tubulopathies.
|
| 25 |
Endiandrin A acts as co-stimulator of colonic epithelial sodium channels
(1 time)
|
Medicine
(1 time)
|
End A (1 time)
GR (1 time)
JNK (1 time)
|
2012 The plant-derived glucocorticoid receptor agonist Endiandrin A acts as co-stimulator of colonic epithelial sodium channels (ENaC) via SGK-1 and MAPKs.
|
| 26 |
endoluminal activation of the epithelial sodium channel
(1 time)
|
Physiology
(1 time)
|
---
|
2019 Proteasuria-The impact of active urinary proteases on sodium retention in nephrotic syndrome.
|
| 27 |
Endothelial Dysfunction via Inflammatory Factor-Mediated Activation of Epithelial Sodium Channel
(1 time)
|
|
COX-2 (1 time)
EDR (1 time)
HHcy (1 time)
|
2021 Homocysteine Causes Endothelial Dysfunction via Inflammatory Factor-Mediated Activation of Epithelial Sodium Channel (ENaC).
|
| 28 |
enhanced amiloride sensitive Na+ conductance
(1 time)
|
Biochemistry
(1 time)
|
cAMP (1 time)
CFTR (1 time)
IBMX (1 time)
|
1997 Inhibition of epithelial Na+ currents by intracellular domains of the cystic fibrosis transmembrane conductance regulator.
|
| 29 |
enhanced plasma aldosterone, ileal activation of epithelial sodium channel
(1 time)
|
Gastroenterology
(1 time)
|
SGLT1 (1 time)
|
2005 Comparative study of epithelial gene expression in the small intestine among total proctocolectomized, dietary sodium-depleted, and aldosterone-infused rats.
|
| 30 |
enters through apical sodium channels
(1 time)
|
Allergy and Immunology
(1 time)
|
AECII (1 time)
ALI (1 time)
LPS (1 time)
|
2012 Sevoflurane reduces severity of acute lung injury possibly by impairing formation of alveolar oedema.
|
| 31 |
entry mechanism: the amiloride-sensitive Na(+) channel
(1 time)
|
Nephrology
(1 time)
|
---
|
2006 A hypothesis linking sodium and lithium reabsorption in the distal nephron.
|
| 32 |
enzyme Na-K-ATPase or inhibit the epithelial sodium channel
(1 time)
|
Endocrine System Diseases
(1 time)
|
IR (1 time)
MS (1 time)
OLF (1 time)
|
2015 Identification of Putative Natriuretic Hormones Isolated from Human Urine.
|
| 33 |
enzyme; stimulation of the epithelial sodium channel
(1 time)
|
Nephrology
(1 time)
|
Ang I (1 time)
Ang II (1 time)
AT1R (1 time)
|
2021 The evolving complexity of the collecting duct renin-angiotensin system in hypertension.
|
| 34 |
epithelia express specific Na(+) channels
(1 time)
|
Biochemistry
(1 time)
|
CFTR (1 time)
|
2002 Where have all the Na+ channels gone? In search of functional ENaC in exocrine pancreas.
|
| 35 |
epithelial Na(+) channel subunit
(1 time)
|
Nephrology
(1 time)
|
Dot (1 time)
NAD (1 time)
|
2013 Epigenetics and the control of the collecting duct epithelial sodium channel.
|
| 36 |
epithelial Na+ channel complex
(1 time)
|
Physiology
(1 time)
|
RPA (1 time)
|
1998 Developmental regulation of epithelial sodium channel subunit mRNA expression in rat colon and lung.
|
| 37 |
epithelial sodium channel alpha-subunit
(1 time)
|
Neoplasms
(1 time)
|
ALI (1 time)
ASK1 (1 time)
HALI (1 time)
|
2016 SOCS-1 rescues IL-1beta-mediated suppression of epithelial sodium channel in mouse lung epithelial cells via ASK-1.
|
| 38 |
epithelial sodium channel sensitive to amiloride
(1 time)
|
Embryology
(1 time)
|
---
|
2012 Expression of the epithelial sodium channel sensitive to amiloride (ENaC) in normal and preeclamptic human placenta.
|
| 39 |
epithelial type of Na(+) channel
(1 time)
|
Biochemistry
(1 time)
|
RVI (1 time)
|
2000 The hypertonicity-induced Na(+) conductance of rat hepatocytes: physiological significance and molecular correlate.
|
| 40 |
epithelium and the activity of alveolar Na(+) channel
(1 time)
|
Cell Biology
(1 time)
|
Ca (1 time)
|
2003 Large conductance Ca2+-activated K+ channels sense acute changes in oxygen tension in alveolar epithelial cells.
|
| 41 |
epithelium, we investigated the role of CFTR in regulating g
(1 time)
|
Physiology
(1 time)
|
CF (1 time)
CFTR (1 time)
|
2003 Functional interaction of CFTR and ENaC in sweat glands.
|
| 42 |
epithelium; and epithelial sodium channel
(1 time)
|
Natural Science Disciplines
(1 time)
|
AQPs (1 time)
|
2019 Distribution of aquaporins and sodium transporters in the gastrointestinal tract of a desert hare, Lepus yarkandensis.
|
| 43 |
ERRalpha, Na/K-ATPase and epithelial sodium channel
(1 time)
|
Chemistry
(1 time)
|
ChIP (1 time)
DS (1 time)
ERRalpha (1 time)
|
2016 High Salt Diet Affects Renal Sodium Excretion and ERRalpha Expression.
|
| 44 |
essential for epithelial sodium channel
(1 time)
|
Physiology
(1 time)
|
PLG (1 time)
uPA (1 time)
|
2019 Urokinase-type plasminogen activator (uPA) is not essential for epithelial sodium channel (ENaC)-mediated sodium retention in experimental nephrotic syndrome.
|
| 45 |
Estrogen negatively regulates the renal epithelial sodium channel
(1 time)
|
Biochemistry
(1 time)
|
---
|
2019 Estrogen negatively regulates the renal epithelial sodium channel (ENaC) by promoting Derlin-1 expression and AMPK activation.
|
| 46 |
ethanol affects epithelial sodium channels
(1 time)
|
Cell Biology
(1 time)
|
ROS (1 time)
TEMPOL (1 time)
|
2012 Ethanol stimulates epithelial sodium channels by elevating reactive oxygen species.
|
| 47 |
examined activation of the human epithelial sodium channel
(1 time)
|
Biochemistry
(1 time)
|
microS (1 time)
|
2009 Alternative mechanism of activation of the epithelial na+ channel by cleavage.
|
| 48 |
examined the mechanism of amiloride-sensitive Na(+) channels
(1 time)
|
Endocrinology
(1 time)
|
---
|
2006 Frog ANP increases the amiloride-sensitive Na(+) channel activity in urinary bladder cells of Japanese tree frog, Hyla japonica.
|
| 49 |
examines whether serine proteases can activate the amiloride-sensitive sodium channel
(1 time)
|
Nephrology
(1 time)
|
---
|
2000 Activation of the amiloride-sensitive epithelial sodium channel by the serine protease mCAP1 expressed in a mouse cortical collecting duct cell line.
|
| 50 |
exchange, and both alveolar epithelial sodium channel
(1 time)
|
Cell Biology
(1 time)
|
AFC (1 time)
OA (1 time)
|
2013 Lipoxin A(4) activates alveolar epithelial sodium channel, Na,K-ATPase, and increases alveolar fluid clearance.
|
| 51 |
exchangers
(1 time)
|
Sexual Dysfunction, Physiological
(1 time)
|
CC (1 time)
EFS (1 time)
ICP (1 time)
|
2019 Amiloride Relaxes Rat Corpus Cavernosum Relaxation InVitro and Increases Intracavernous Pressure InVivo.
|
| 52 |
excretion and renal epithelial sodium channel
(1 time)
|
Vascular Diseases
(1 time)
|
HS (1 time)
TRPV1 (1 time)
WT (1 time)
|
2014 Transient receptor potential vanilloid 1 activation by dietary capsaicin promotes urinary sodium excretion by inhibiting epithelial sodium channel alpha subunit-mediated sodium reabsorption.
|
| 53 |
excretion by altering the activity of epithelial sodium channels
(1 time)
|
Receptors, Purinergic
(1 time)
|
BP (1 time)
RAAS (1 time)
|
2009 ENaC, renal sodium excretion and extracellular ATP.
|
| 54 |
explanation is that alcohol regulates epithelial sodium channels
(1 time)
|
Medicine
(1 time)
|
ARDS (1 time)
EtOH (1 time)
NOX (1 time)
|
2013 Ethanol alters alveolar fluid balance via Nadph oxidase (NOX) signaling to epithelial sodium channels (ENaC) in the lung.
|
| 55 |
expressed low-conductance amiloride sensitive sodium channels
(1 time)
|
Molecular Biology
(1 time)
|
---
|
1998 Environmental KCl causes an upregulation of apical membrane maxi K and ENaC channels in everted Ambystoma collecting tubule.
|
| 56 |
expressed the amiloride-sensitive Na(+) channel
(1 time)
|
Nephrology
(1 time)
|
DCT (1 time)
mDCT (1 time)
NCC (1 time)
|
2004 In vitro characterization of aldosterone and cAMP effects in mouse distal convoluted tubule cells.
|
| 57 |
expression and cellular localization of epithelial sodium channel
(1 time)
|
Biochemistry
(1 time)
|
gamma2MSH (1 time)
MC3R (1 time)
|
2013 Gamma-melanocyte stimulating hormone regulates the expression and cellular localization of epithelial sodium channel in inner medullary collecting duct cells.
|
| 58 |
expression and increased activity of vascular epithelial sodium channel
(1 time)
|
Vascular Diseases
(1 time)
|
IMA (1 time)
|
2022 Epithelial Sodium Channel delta Subunit Is Expressed in Human Arteries and Has Potential Association With Hypertension.
|
| 59 |
expression and modulation of the amiloride-sensitive epithelial sodium channel
(1 time)
|
Pulmonary Medicine
(1 time)
|
---
|
2004 Spectrum of ion channels in alveolar epithelial cells: implications for alveolar fluid balance.
|
| 60 |
expression of amiloride sensitive sodium channels
(1 time)
|
Biochemistry
(1 time)
|
---
|
2011 ENaC channels in oocytes from Xenopus laevis and their regulation by xShroom1 protein.
|
| 61 |
expression of apical Na+ channels
(1 time)
|
Pathology
(1 time)
|
UC (1 time)
|
2004 Decreased expression of apical Na+ channels and basolateral Na+, K+-ATPase in ulcerative colitis.
|
| 62 |
expression of AQP, Na+,K(+)-ATPase and the amiloride-sensitive Na+ channel
(1 time)
|
Physiology
(1 time)
|
AQP (1 time)
|
1997 Perinatal changes in expression of aquaporin-4 and other water and ion transporters in rat lung.
|
| 63 |
expression of epithelial sodium channel
(1 time)
|
Cardiology
(1 time)
|
ET-1 (1 time)
|
2006 Endothelin ETA receptor blockade with darusentan increases sodium and potassium excretion in aging rats.
|
| 64 |
expression of mucin and sodium channel
(1 time)
|
Pulmonary Medicine
(1 time)
|
CD (1 time)
COPD (1 time)
scRNA-seq (1 time)
|
2022 Smoking induces shifts in cellular composition and transcriptome within the bronchial mucus barrier.
|
| 65 |
expression of Na(+) channel
(1 time)
|
Cell Biology
(1 time)
|
HME (1 time)
|
2007 P2Y receptor regulation of sodium transport in human mammary epithelial cells.
|
| 66 |
number (N) and open probability (P(o)) of epithelial sodium channels
(1 time)
|
Biochemistry
(1 time)
|
GST (1 time)
S1A (1 time)
|
2004 Syntaxin 1A regulates ENaC channel activity.
|
| 67 |
well-established amiloride-sensitive Na(+) channel
(1 time)
|
Physiology
(1 time)
|
CNG (1 time)
PsTx (1 time)
|
2011 Alveolar epithelial CNGA1 channels mediate cGMP-stimulated, amiloride-insensitive, lung liquid absorption.
|
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